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Mammalian in Medical News

International team cracks mammalian gene control code

An international consortium of scientists, including researchers from The University of Queensland (UQ), have probed further into the human genome than ever before. They have discovered how genes are controlled in mammals, as well as the tiniest genetic element ever found. Their discoverie...

CSHL neuroscientists propose project to comprehensively map mammalian brain circuits

Cold Spring Harbor, NY -- Thirty-seven scientists from Cold Spring Harbor Laboratory (CSHL) and 20 other major research institutions in the U.S. and Europe have issued a major challenge to the neuroscience community. At long last, the time has come, they argue in a just-published paper, to assemb...

Crystallography reveals the 3-D structure of mammalian sperm receptor

Scientists at the Swedish medical university Karolinska Institutet have determined the first 3D structure of ZP3, a protein essential for the interaction between the mammalian egg coat and sperm. The findings, presented in Nature , gives a first glimpse into the molecular architecture of animal e...

Medical College of Wisconsin researchers identify proteins that help develop mammalian hearts

The absence of two proteins in mammalian embryos prevents the development of a healthy heart, a new study by researchers at the Medical College of Wisconsin, Milwaukee, has found. The study, which appears in the May 15 issue of Developmental Biology, was led by Stephen Duncan, Ph.D., professor ...

Cannibalistic Signals Help Mammalian Embryos Develop Normally

A process called autophagy spurs dying embryonic stem cells to send cannibalistic signals to have their corpses purged, a last gasp that paves the way for normal mammalian// development. Autophagy is the way cells devour their own unwanted or damaged parts. It was known to be active in cell d...

Filling a Niche -- Role of Rb in Mammalian Stem Cells

Drs. Gustavo Leone and Michael Robinson (Ohio State University) and colleagues uncover a stem-cell specific role for the well-known tumor suppressor gene// , Rb, in the developing mammalian embryo. Researchers had previously shown that mice deficient in Rb die as embryos. Using a combination...
Mammalian in Medical Technology

DSM Announces Yield Boosts of 5-10 Fold With XD(R) Technology for Mammalian Manufacturing Platforms

PARSIPPANY, N.J., May 18 /PRNewswire/ -- DSM announced today that its proprietary XD(R) Technology boosts bioreactor productivity and titers of mammalian cell culture processes by 5-10 fold for the production of proteins and antibodies. Recent studies completed at the R&D labs of DSM Biol...

First High-Res 3-D Structures of Mammalian HSP90 Protein Solved, Key to Better Targets for AIDS, Sepsis, Cancer Drugs

HWI Scientist Dr. Dan Gewirth's Groundbreaking Research Makes Cover of Molecular Cell BUFFALO, N.Y., Oct. 19 /PRNewswire/ -- Dr. Dan Gewirth, Hauptman-Woodward senior research scientist, has just solved the structure of the first mammalian GRP94 protein implicated ...

St. Jude Settles Century-Old Debate on Origin of Mammalian Network of Lymphatic Vessels

Embryonic veins are the source of cells that multiply and migrate in the embryo to give rise to the entire network of lymphatic vessels, a finding that suggests that these cells might one day be used to grow new vessels MEMPHIS, Tenn., Oct. 3 /PRNewswire-USNewswire/ -- Investigators at St. ...

Juvenile Diabetes Research Foundation, The Genomics Institute of the Novartis Research Foundation Announce Innovative Diabetes Drug Discovery and Development Partnership

... and proteomics tools, medicinal chemistry, cell-based ultra high throughput screening of genes or compounds, structural genomics, and forward/reverse mammalian genetics. The mission of the Institute is to exploit these technologies to identify new biological processes and understand the underlying mech...

Researchers Create First Targeted Knockout Rats Using Zinc Finger Nuclease Technology

...lls and zebrafish embryos and are now in human clinical trials for the treatment of HIV/AIDS. This is the first example of successful gene editing in mammalian embryos using this technology. "Our ZFN technology is widely applicable across species," stated Philip Gregory, D.Phil., Sangamo's vice presi...

Sangamo BioSciences Announces Achievement of Key Milestone in Cell Engineering Agreement With Genentech

...acteristics of biologic drugs, such as antibodies, that are manufactured in mammalian cells." "Our ZFNs provide the gold standard technology for specifically editing target genes in mammalian cells," stated Philip Gregory, D. Phil., Sangamo's vice president of resear...
Mammalian in Medical Products

Gentamicin Sulfate: Liquid

Description:...ial protein synthesis by binding to the 30S subunit of ribosomes. Its suggested working concentration of 50 mg/L is generally non-toxic to viruses and mammalian cells, thereby making a gentler alternative to penicillin and steptomycin. While it is useful for treating persistent contaminants, it is also benefic...
Company:CellGro by Mediatech

Gentamycin Sulfate: Powder

Description:...ial protein synthesis by binding to the 30S subunit of ribosomes. Its suggested working concentration of 50 mg/L is generally non-toxic to viruses and mammalian cells, thereby making a gentler alternative to penicillin and steptomycin. While it is useful for treating persistent contaminants, it is also benefic...
Company:CellGro by Mediatech
Mammalian in Medical Dictionary

Vitamin C

... Vitamin C or L-ascorbic acid is an essential nutrient for humans, a large number of higher primate species, a small number of other mammalian species, a few species of birds, and some fish. Linus Pauling Institute at Oregon State University ... Vitamin C is required for the synthesis...

Scotoma

...nic simple glaucoma a sickle-shaped scotoma appearing ... A form of Bjerrum's scotoma (arcuate scotoma seen in glaucoma) ... Every normal mammalian eye has a scotoma in its field of vision, usually termed its blind spot. ... presence of the scotoma can be demonstrated subjectively ... Ho...

Prostate

... The prostate is a compound tubuloalveolar exocrine gland of the male mammalian reproductive system. Females also have prostate glands, previously called paraurethral or Skene's glands, connected to the distal third of the...

Oxytocin

... Oxytocin (pronounced /ˌɒksɨˈtoʊsɪn/) is a mammalian hormone that also acts as a ... One international unit (IU) of oxytocin..... Oxytocic— Oxytocin ; ... Oxytocin (Greek: "quick birth", OXT) is a mammalian hormone that is secreted ... During lactation, oxytocin is secreted in ...

Moles

...s causes, treatment, including how to get rid of skin moles . ... Large moles present at birth. ... Moles are not rodents but belong to the mammalian Order Insectivora. Insectivora means insect eater, and this group includes moles , shrews, and hedgehogs. ... The medical term for a mole is a ...

Lice

...er 3,000 species of wingless insects; three of which are classified as human disease agents. They are obligate ectoparasites of every avian and most mammalian orders. They are... The head louse is an obligate ectoparasite of humans. Head lice are wingless insects spending their entire life on human sca...
Mammalian in Biological News

ExcellGene and Khner achieved milestone in development of novel 250 Liter mammalian cell culture bioreactors

May 12, 2009 / b3c newswire / - ExcellGene SA, Monthey and Adolf Kühner AG, Birsfelden announce today that they achieved an important milestone in the development of a revolutionary cell culture technology for scale up and manufacturing from suspension cultured mammalian cells. As part of a...

Atomic structure of the mammalian 'fatty acid factory' determined

Mammalian fatty acid synthase is one of the most complex molecular synthetic machines in human cells. It is also a promising target for the development of anti-cancer and anti-obesity drugs and the treatment of metabolic disorders. Now researchers at ETH Zurich have determined the atomic structure...

Adult stem cells activated in mammalian brain

Irvine, Calif., July 24, 2008 Adult stem cells originate in a different part of the brain than is commonly believed, and with proper stimulation they can produce new brain cells to replace those lost to disease or injury, a study by UC Irvine scientists has shown. Evidence strongly shows that ...

A mammalian clock protein responds directly to light

We all know that light effects the growth and development of plants, but what effect does light have on humans and animals? A new paper by Nathalie Hoang et al., published in PLoS Biology this week, explores this question by examining cryptochromes in flies, mice, and humans. In plants, cryptoch...

First high-res 3D structures of mammalian HSP90 protein solved

Dr. Dan Gewirth, Hauptman-Woodward senior research scientist, has just solved the structure of the first mammalian GRP94 protein implicated in immune diseases such as sepsis, AIDS and certain cancers. His work is being published today in a cover article in a top scientific journal - Molecular Cel...

St. Jude settles century-old debate on origin of mammalian network of lymphatic vessels

Investigators at St. Jude Children's Research Hospital settled a century-old debate on the origin of the mammalian lymphatic vasculaturethe network of vessels and capillaries critical to various essential housekeeping functions in the body. The finding holds the promise for the development of new ...

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Mammalian in Biological Technology

Med Discovery and Laborium Biopharma Extend Their Development Partnership to Include Mammalian Cell Culture Processes and Clinical Manufacturing for All Products in Med Discovery's Portfolio

Med Discovery SA, a specialized protein-based therapeutics oncology company, is proud to announce that they have extended their global partnership agreement with Laborium Biopharma, a subsidiary of Validapro BioSciences Inc. to encompass the cell culture process development and clinical manufactu...

New Study Finds Growth Factor Boosts Productivity in Mammalian Cell Culture

Leading researchers in academia and industry reveal powerful effects of recombinant lactoferrin (tradename: Lacromin) in mammalian cell culture leading to a significant boost in productivity. FORT COLLINS, Colo., Oct. 10 /PRNewswire/ -- A recently published study in the scientific...

InVitria's Cellastim Delivers Superior Results in Mammalian Cell Culture

FORT COLLINS, Colo., Sept. 25 /PRNewswire/ -- Steve Pettit, Director of the company's Cell Culture Group, presented results of InVitria's ( http://www.InVitria.com ) Cellastim in mammalian cell culture at the 2008 BioProcess International Conference in Anaheim, California this week. "Cellast...

KGI Offers Mammalian Cell Culture Program for Biotech Industry Professionals

CLAREMONT, Calif., Sept. 18 /PRNewswire/ -- Keck Graduate Institute (KGI) today announced that it will conduct a five-day program for industry professionals to learn the latest developments in mammalian cell culture, from November 2-7, 2008. "Mammalian cell biotechnology has undergone explos...

Rentschler Biotechnologie Extends Capacities for Mammalian Cell Culture Manufacturing

Laupheim, Germany – June 20, 2008 / b3c newswire /  - Rentschler Biotechnologie, a leading full-service contract manufacturing organization (CMO) for the development and production of biopharmaceuticals in mammalian cells, started operation of a 2,500 L multi-process production suite....

Seth Dobin heading up Marshfield's Mammalian Genotyping Service

Marshfield, Wis. -- Research scientist Seth Dobrin, Ph.D., has been named the new head of the Center for Human Genetics' Mammalian Genotyping Service of the Marshfield Clinic Research Foundation. He plans to apply his experience in genetics and genomics research to problems of mental health an...

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Mammalian in Biological Products

CheckMate Mammalian Two-Hybrid System from Promega

Description: ...
Company:Promega

PhosphoSafe Extraction Buffer from Novagen

Description:... PhosphoSafe Extraction Reagent extracts cytosolic proteins from mammalian and insect cells while preserving their phosphorylation state. The reagent, an enhancement of the CytoBuster Protein Extraction reagent, includes four...
Company:Novagen

GenoStat Inducible Expression System from Upstate

Description:...n System provides tightly regulated control of exogenous gene expression in mammalian cells and is capable of repeated on/off expression kinetics. This degree of...tilizing the GenoStat Inducible Expression System is unmatched by any other mammalian expression system on the market. Applications: RNAi/siRNA/Gene Kno...
Company:Upstate

mirVana™ qRT-PCR Primer Set for Normalization (5S) from Ambion

Description:...c 2005 Quantitative results in less than 3 hours Detection from as little as 25 pg of total RNA Specific primers available for hundreds of mammalian miRNAs Suitable for either real-time or end-point RT-PCR Ideal for validating expression profiling data and high-throughput applications ...
Company:Ambion

SelectFX Alexa Fluor 488 Cytochrome c Apoptosis Detection Kit - for fixed cells from Molecular Probes (Invitrogen)

Description:...ilters and instrument settings appropriate for fluorescein. The kit also includes cell fixative and permeabilization reagents as well as protocols for mammalian cell preparation and staining....
Company:Molecular Probes (Invitrogen)

Anti-GLP-1 (7-36) (Glucagon-like peptide-1), C-terminus amide-reactive Polyclonal Antibody, Unconjugated from CHEMICON

Description:...ptides such as hGLP-2, glucagon, hGIP and VIP. SPECIES REACTIVITIES: Most mammalian species. GLP-1 is identical in all mammalian species studied except guinea pig and presumably its South American rodent ...
Company:CHEMICON
Mammalian in Biological Definition

Adaptive radiation

...created by the environmental change. An example of adaptive radiation as the result of an environmental change is the rapid spread and development of mammalian species after the extinction of the dinosaurs. Archipelagoes . Isolated ecosystems , such as islands and mountain areas, can be colonized by a...

Anaphase

...lls on astral microtubules that have attached to the cell cortex. The contributions of anaphase A and anaphase B to anaphase vary with cell type. In mammalian cells anaphase B follows shortly after anaphase A and extends the spindle to around twice its metaphase length; in contrast yeast and certain pro...

Antibiotic

...the cellular and molecular physiology of the bacterial cell and that of the mammalian cell. In contrast, despite the seemingly huge differences between fungi and humans, the basic biochemistries of the fungal cell and the mammalian cell are much more similar; so much so that there are few therapeutic oppor...

Apoptosis

...tream from TNF-R1 and Fas activation - at least in mammalian cells - a balance between pro- (like BAX, BID, or ...not, actually, a single gene but a whole family of mammalian genes). Indeed, around four years before, in landm...king in Horvitz's laboratory identified ICE as the mammalian counterpart of CED-3 (that is, the product of the ...

Barr body

... remain active and expressed in some species. These genes are generally those which are present on the other sex chromosome (Y or W). Mechanism mammalian X-chromosome inactivation is initiated from the X inactivation centre or Xic , usually found near the centromere . The centre contains twelve genes,...

Biotechnology

... of substances like insulin or antibiotics . It can also refer to transgenic animals or transgenic plants , such as Bt corn. Genetically altered mammalian cells, such as Chinese Hamster ovarian cells, are also widely used to manufacture pharmaceuticals. Another promising new biotechnology application is...
Mammalian in Biological Dictionary

Zona pellucida

..., solid, transparent outer membrane of a developed mammalian ovum. ... Zona pellucida domain proteins" ... zona pellucida thick membrane around the mammalian ovum; can be penetrated by one sperm in the fer...trix is known as the zona pellucida ... The mammalian zona pellucida is an extracellular matrix that...

Y chromosome

...osome DNA haplogroups. Single-origin hypothesis ... But the human Y chromosome , at the same time, plays a central role in human ... Thus, mammalian embryos with a Y chromosome develop testes, while those without ... Cheer up, guys. Your favorite chromosome is turning out to be not just an...

Viral oncogene

...ukosis , ... If the viral LTRs are close enough to that oncogene , they will upregulate ... This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, ... Kidney Gene DataBase. Name. v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog ... Human Kidney Gene DataBase. Name....

Transient transfection

...eering & Biotechnology News - Biotechnology from Bench ... MAX transfection reagent, which was ... Scalable Transient Protein Production In mammalian Cells - This course ... culture medium for transient transfection . cell culture analysis and monitoring ... Transient transfection in...

Transfection

...ssion, Gene Silencing,RNA interference, primary cell culture, and sample ... Transfection . Contact Us. Catalog. All Products. All Technical ... mammalian Transfection System. This calcium phosphate-mediated transfection system contains ... Some cells exhibit similar transfection efficiencies w...

Transcriptome

... and Comparison Database. Searchable ... Recent large-scale transcript mapping experiments suggest that many more ... The structures of typical mammalian genes, consisting of many small coding ... Compare our book prices. Bioinformatics In The Post-Genomic Era: Genome, Transcriptome , Proteome, And ...
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