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ANTIGEN in Medical News

PharmAthene, Inc. Announces $19.3 Million Private Placement of Convertible Notes and Common Stock Warrants

... - a second generation recombinant protective antigen (rPA) anthrax vaccine Third generation rPA ... agents RypVax(TM) - a recombinant dual antigen vaccine for plague For more ... Proposals for an Anthrax Recombinant Protective antigen (rPA) Vaccine for the Strategic National ...

CEL-SCI Expands Testing of Its Vaccine to Determine Efficacy Against More Virulent Strain of H1N1 Swine and Other Influenza Viruses

... proprietary L.E.A.P.S. technology (Ligand Epitope antigen Presentation System) to determine its efficacy ... to induce and elicit protective immunity and antigen specific antibody production in animal models. ... constructs are chimeric peptides which combine antigen specificity with immune response modulation. ...

Early Detection of Melanoma Plus Regular Skin Exams is Vital For Beating Disease

... targeted antibody known as MART-1 (Melanoma antigen Recognized by T cells), which improves the speed ... to test a vaccine known as the MAGE-A (melanoma antigen - family A) vaccine that would be used as an ... types of stage III and IV melanoma. MAGE is an antigen that exists in every cell in the body, but it is ...

PharmAthene Reports Year End 2008 Financial Results

... novel second generation recombinant protective antigen vaccine candidate, has been selected by the ... of 25 million doses of a recombinant protective antigen vaccine for the Strategic National Stockpile. ... - a second generation recombinant protective antigen (rPA) anthrax vaccine Valortim(R) - a ...

American Urological Association Statement in Support of Prostate-Specific Antigen Testing

... Journal of Medicine about prostate-specific antigen (PSA) testing. The American Urological ... the two studies about prostate-specific antigen (PSA) testing recently published in the New ... Best Practice Statement about prostate-specific antigen testing that will be unveiled during our upcoming ...

Polymedco Introduces Point of Care Test for Recurrent Bladder Cancer Detection

... BTA stat(R) Test Detects Bladder Tumor Associated antigen in Urine CORTLANDT MANOR, N.Y., Jan. 29 ... detect the presence of bladder tumor associated antigen in urine. It is a single-step, rapid immunochromatographic assay for bladder tumor-associated antigen in voided urine. The specificity of the BTA ...

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ANTIGEN in Medical Technology

PharmAthene Submits Proposal to BARDA in Response to Broad Agency Announcement for Advanced Research and Development for Valortim(R)

... protein component known as the anthrax Protective antigen (PA) of the lethal and edema toxin complexes ... - a second generation recombinant protective antigen (rPA) anthrax vaccine Valortim(R) - a ... agents RypVax(TM) - a recombinant dual antigen vaccine for plague A third generation rPA ...

PharmAthene Submits SparVax(TM) Regulatory Strategy to FDA

... a next generation recombinant protective antigen anthrax vaccine. The FDA submission is in ... - a second generation recombinant protective antigen (rPA) anthrax vaccine Third generation ... agents RypVax(TM) - a recombinant dual antigen vaccine for plague For more ...

Human Genome Sciences Submits Biologics License Application to FDA for ABthrax(TM)

... infection at the cellular level. After protective antigen and the anthrax toxins are produced by the bacteria, protective antigen binds to the anthrax toxin receptor on cell ... Raxibacumab blocks the binding of protective antigen to cell surfaces and prevents the anthrax toxins ...

Novel Valortim(R) Mechanism of Action Data Presented at the Keystone Symposia on Molecular and Cellular Biology

... protein component known as the anthrax Protective antigen (PA) of the lethal toxin complex produced by the ... - a second generation recombinant protective antigen (rPA) anthrax vaccine Valortim(R) - a ... agents RypVax(TM) - a recombinant dual antigen vaccine for plague A third generation rPA ...

Human Genome Sciences Begins Delivery of First-in-Class Anthrax Treatment to U.S. Strategic National Stockpile

... antibody to Bacillus anthracis protective antigen that was discovered and developed by HGS, using ... Technology. Research has shown that protective antigen is the key facilitator in the progression of ... at the cellular level. After protective antigen and the anthrax toxins are produced by the ...

PharmAthene Presents Data for Protexia(R) and Valortim(R) at 2008 BARDA Industry Conference / PHEMCE Stakeholders Workshop

... to assess anthrax bacteremia and protective antigen in blood. Samples were analyzed for protective ... protein component known as the anthrax protective antigen of the lethal toxin complex produced by the ... is designed to target anthrax protective antigen and protect the cells from damage by the anthrax ...

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ANTIGEN in Medical Products

ImmunoWELL EBV VCA IgG Test

Description:... IgG antibody to Epstein-Barr Virus viral capsid antigen (VCA) in human serum. When the VCA IgG test is ... with other testing such as the EBV nuclear antigen (EBNA-1), VCA IgM, and EBV early antigen tests and/or heterophile tests, the results can ...
Company:GenBio

ImmunoWELL EBV VCA IgM Test

Description:... IgM antibody to Epstein-Barr Virus viral capsid antigen (VCA) in human serum. When the VCA IgM test is ... with other testing such as the EBV nuclear antigen (EBNA-1), VCA IgG, and EBV early antigen tests and/or heterophile tests, the results can ...
Company:GenBio

Epstein-Barr virus (EBV) ELISA

Description:... Virus, and includes tests for Viral Capsid antigen (VCA), Early antigen (EA), and Nuclear antigen (EBNA). Most Wampole EBV assays utilize ...
Company:Wampole Laboratories

Antigen-Antibody Pen For Hamster Primary antibodies

Description:... antigen-bonded colored dyes helps to see antigen being written on the membrane. One can mark the ... Unlike the situation in Fig.1C, the use of antigen pens allows the markings to be visible at the ... if one is using rabbit primary antibody and the antigen pens specific for rabbit, then the secondary ...
Company:Alpha Diagnostic International, Inc.

Antigen-Antibody Pen For Rabbit Primary antibodies

Description:... antigen-bonded colored dyes helps to see antigen being written on the membrane. One can mark the ... Unlike the situation in Fig.1C, the use of antigen pens allows the markings to be visible at the ... if one is using rabbit primary antibody and the antigen pens specific for rabbit, then the secondary ...
Company:Alpha Diagnostic International, Inc.

Antigen-Antibody Pen For Sheep Primary antibodies

Description:... antigen-bonded colored dyes helps to see antigen being written on the membrane. One can mark the ... Unlike the situation in Fig.1C, the use of antigen pens allows the markings to be visible at the ... if one is using rabbit primary antibody and the antigen pens specific for rabbit, then the secondary ...
Company:Alpha Diagnostic International, Inc.

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ANTIGEN in Medical Definition

Central tolerance

... expression within the organ and importation of antigen due to circulation from peripheral sites. In the ... T cell central tolerance, additional sources of antigen are made available in the thymus by the action of ... ( Monoclonal antibodies , Autoantibody ) • antigen • APC • MHC Immunity • Autoimmunity ...

Artificial induction of immunity

... the immune response of simpler immunogenic molecules (known as antigens ) is to conjugate the antigens. Conjugation is the attachment to the antigen of another substance which also generates an immune response, thus amplifying the overall response and causing a more robust immune memory to the ...

Thymocyte

... chemokine receptors. J Immunol. 2007 Feb 15;178(4):2008-17. http://www.jimmunol.org/cgi/content/full/178/4/2008 ] ^ Sleckman BP, Lymphocyte antigen receptor gene assembly: multiple layers of regulation. Immunol Res 32:153-8, 2005. full text ^ Baldwin TA, Hogquist KA, Jameson SC, The ...
ANTIGEN in Medical Dictionary

Anaphylaxis

... introduction of a foreign protein or other antigen into the body tissue s. Anaphylaxis : ... reaction to a previously encountered antigen . Antibody An immune system protein made to fight infection . antigen A foreign substance detected that provokes an ...

Antibody

... cells ( plasma cells) as a reaction to an antigen (foreign substance) for the purpose of host ... of the body's past experience or exposure to an antigen , or something that the body does not recognize ... a weapon against foreign invaders in the body. antigen The chemical that stimulates an immune response ....

Antigen

... antigen ic drift: A mechanism for variation by virus es ... previous strains making it easier for ... antigen - A foreign substance, bacteria , or virus ... possible by a generous donation from: ... The antigen tests are used if the person has a medical ...

B virus

... outer capsule contains the hepatitis B surface antigen (HBsAg). The inner core contains HBV core antigen (HBcAg) and hepatitis B e- antigen (HBeAg). Hepatitis B virus (HBV) causes a ...

Complement

... process and serve as the primary mediator in antigen - antibody reactions of the B cell mediated ... can be started in several ways, especially by antigen - antibody complexes. Alternative or ... sequence of events, usually triggered by an antigen - antibody complex, in which each component of ...

Delta

... (THC), ... T-cells, the antigen peptides must be presented on Class II MHC, and in the case of killer T-cells , the antigen peptides must be presented on Class I MHC. The T- cell antigen receptor consists of either an alpha / beta ...

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ANTIGEN in Biological News

New evidence explains poor infant immune response to certain vaccines, says MU researcher

... reacted when they were repeatedly exposed to an antigen that simulates a virus. Zaghouani found that while the antigen would prompt a response of the immune system, it ... to help destroy the foreign microbes. When an antigen from a vaccine enters a body with a mature immune ...

From foe to friend: Researchers use salmonella as a way to administer vaccines in the body

... organism that can effectively deliver an antigen in the body. The researchers report that they ... and effective means of biological containment for antigen delivery. The method not only effectively delivers the antigen in the body, but does so in a way that does not ...

A protein sequence associated with Huntington’s disease may become life-saving vaccine component

... The major component of every vaccine is an antigen that elicits specific immunity to a particular ... test if attachment of a long polyQ "tail" to an antigen can enhance immune response to vaccination". First, he noticed that small aggregates formed by an antigen fused to a polyQ tail resembled the droplets that ...

New technology for boosting vaccine efficiency

... of two major elements. First, each vaccine antigen should be made in two forms. One is easily ... to the chopping. Thus both these forms of an antigen would be used in combination to elicit a much ... presented by the cell to our immune system. This antigen presentation process is very complex and remains ...

Arbor Vita rapid H5N1 flu diagnostic presented at ICEID meeting

... Research Center (NHRC) suggests that a rapid antigen assay test developed by Arbor Vita Corporation ... protein, as opposed to the nucleoprotein (NP). antigen capture is mediated through a PDZ protein, which ... assay is the familiar lateral-flow rapid antigen assay. However, the role of the capture antibody ...

Gene therapy protocol at UCSD activates immune system in patients with leukemia

... antibodies reactive with a leukemia-associated antigen a protein made by leukemia cells that can ... system to produce antibodies called ROR1. This antigen appears to be found only on the cell surface of ... said. He also noted that because the ROR1 antigen is found only on leukemia cells, it could be ...

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ANTIGEN in Biological Technology

PharmAthene, Inc. Closes on $19.3 Million Private Placement of Convertible Notes and Common Stock Warrants

... - a second generation recombinant protective antigen (rPA) anthrax vaccine Third ... RypVax(TM) - a recombinant dual antigen vaccine for plague For more ... Proposals for an Anthrax Recombinant Protective antigen (rPA) Vaccine for the Strategic National ...

Abbott HIV Test Demonstrates Earlier Disease Detection

... immunoassay test designed to detect HIV p24 antigen and antibodies to HIV type 1 (HIV-1 Group M and ... ARCHITECT HIV Combo (Ag/Ab) incorporates HIV p24 antigen detection which enables laboratories to diagnose ... before HIV antibodies are detectable. HIV p24 antigen is a viral protein of the HIV antigen. ...

Human Genome Sciences Announces New Order for Raxibacumab (ABthrax(TM)) from U.S. Government

... infection at the cellular level. After protective antigen and the anthrax toxins are produced by the bacteria, protective antigen binds to the anthrax toxin receptor on cell ... Raxibacumab blocks the binding of protective antigen to cell surfaces and prevents the anthrax toxins ...

Significant Milestone Marks the Beginning of FDA-Authorized Breast Cancer Trial

... use of dendritic cell therapy using the oncofetal antigen ("OFA"), or iLRP -- immature Laminin Receptor Protein, as a cancer antigen (a protein found on cancer cells that can be ... normal, healthy tissue. QI believes that the OFA antigen can serve as a unique, valuable and ...

PharmAthene's 2nd Generation rPA Anthrax Vaccine, SparVax(TM), Completes FDA Regulatory Strategy Review

... next generation recombinant protective antigen (rPA) anthrax vaccine. In response to ... - a second generation recombinant protective antigen (rPA) anthrax vaccine Third generation ... agents RypVax(TM) - a recombinant dual antigen vaccine for plague For more ...

Data Published in The New England Journal of Medicine Support Use of Raxibacumab (ABthrax(TM)) for the Treatment of Inhalation Anthrax

... infection at the cellular level. After protective antigen and the anthrax toxins are produced by the bacteria, protective antigen binds to the anthrax toxin receptor on cell ... Raxibacumab blocks the binding of protective antigen to cell surfaces and prevents the anthrax toxins ...

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ANTIGEN in Biological Products

Phospho-peptide Antibody from Proteintech Group, Inc.

Description:... Peptide antigen Design Customer Peptide Synthesis ... x1/each Purification of antiserum over antigen (30 ml) Conjugation of antigen peptide to Sepharose, 3 ml column Written ...
Company:Proteintech Group, Inc.

Polyclonal Antibody Production from Agro-Bio

Description:... protocol optimized in time, quantity of antigen and quality of the antibodies obtained. We ... (pre-immune serum) Immunize with antigen in Complete Freund's Adjuvant (CFA) Day 14 : Immunize with antigen in Incomplete Freund's Adjuvant (IFA) Day 28 : ...
Company:Agro-Bio

Mouse Anti-Salmonella typhimurium Monoclonal Antibody, Unconjugated, Clone 6331 from GeneTex

Description:... possess 3 major antigens; the "H" or flagellar antigen (phase 1 & 2), the "O" or somatic antigen (part of the LPS moiety) and the "Vi" or capsular antigen (referred to as "K" in other Enterobacteriaceae). ...
Company:GeneTex

Mouse GM CSF ELISA construction Kit from Antigenix America Inc.

Description:... Mouse GM CSF Construction Kit provides antigen affinity purified polyclonal capture and tracer antibodies, and antigen standard for development of approximately ten microplate ....
Company:Antigenix America Inc.

Human BMP 2 ELISA construction Kit from Antigenix America Inc.

Description:... Human BMP 2 Construction Kit provides antigen affinity purified polyclonal capture and tracer antibodies, and antigen standard for development of approximately ten microplate ....
Company:Antigenix America Inc.

EZ-Retriever System from BioGenex

Description:... temperature-controlled microwave oven for use in DeWax, Rehydration and antigen Retrieval of formalin-fixed, paraffin-embedded tissue sections. It offers ... conjunction with the EZ-AR Solutions, it offers standardized protocols for antigen ....
Company:BioGenex

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ANTIGEN in Biological Definition

Antibody

... viruses . Each antibody recognizes a specific antigen unique to its target. Contents ... and the light chain, which together shape the antigen binding site at the amino terminal end of the ... to note that to produce such a diversity of antigen binding sites with a separate gene for each ...

Antigen

... An antigen is any molecule that is recognized by antibodies . Usually, an antigen is a protein or a polysaccharide , but it can ... amino acids in a protein). Tolerogen - An antigen that invokes a specific immune unresponsiveness ...

Apoptosis

... say, from a malignant mutation) or with foreign antigen produced as a consequence of a viral infection. ... shapes of their receptors do not engage any antigen of significance), or dangerous to their own ... and those that show high affinity to healthy self antigen are killed via apoptosis. Be aware that the ...

Immune system

... most important examples are the mechanisms of antigen presentation. After they leave the thymus, T ... T cells (CTLs). Activation is provided by antigen presenting cells (APCs). A major category of APCs ... a DC simulatenously binds to a T "helper" cell's antigen receptor and to its CD28 receptor, which ...

Monoclonal antibody

... Production If a foreign substance (an antigen ) is injected into a vertebrate such as a ... are then tested for their ability to bind to the antigen (for example with a test such as ELISA ), and ... the small variation (if any) in recognizing the antigen helps to reduce side effects. However, there are ...

Blood type

... with type A blood have red blood cells with antigen A on their surface and produce antibodies against antigen B in their blood serum. Using the blood ... type B blood have the opposite arrangement, antigen B on the cell and produce antibodies to substance ...

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ANTIGEN in Biological Dictionary

Rhesus factor

... Rh factor are equivalent and refer to the Rh D antigen only. The Rhesus Factor . GENOTYPING ... ... online ... rhesus factor - a blood group antigen possessed by Rh-positive people; if an Rh ... ... discovered in the ... Landsteiner called this antigen the Rh ( Rhesus ) factor . ... The rhesus ...

Humoral immunity

... by antibodies. ... For humoral immunity , an antigen is anything an antibody can bind to, though ...... involves the recognition of extracellular antigen by B ... Textbook Reference - Figure 18.17, ... ... PASSIVE AND ACTIVE HUMORAL IMMUNITY . antigen DEPENDENT B CELL DEVELOPMENT ... Humoral ...

Dendritic cell

... cell migration. Cytokines & Receptors. antigen presentation. Cancer research ... 17/04/2009 ... foreign in ... Dendritic cells specialize in antigen presentation and are thought to be more ... ... therapeutic tunes. ... A mature dendritic antigen presenting cell , produced from a processed ... ...

Antigens

... A antibody generator or antigen (Ag) is a substance that prompts the generation ... that can ... The human leukocyte antigen system (HLA) is the name of the major ... and more. Second merozoite surface antigen unrelated to MSP-1. ... These antigens were ...

Antigen

... A antibody generator or antigen (Ag) is a substance that prompts the generation ... encompasses all substances that can ... antigen also antigene ( ) n. A substance that when introduced into the body stimulates the ... antigen -antibody reactions serve as host defenses ...

Somatic hypermutation

... Somatic Hypermutation Assay - Gel Detection. Rearrangements of the antigen receptor genes occur during ontogeny in B and T lymphocytes. ... ... ... Evolution and the molecular basis of somatic hypermutation of antigen receptor genes. ... to evolution immune somatic - hypermutation by ...

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