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Antibody in Medical News

Micromet, Inc. Reports Second Quarter 2009 Financial Results

... BiTE antibodies as well as Micromet's BiTE antibody MT110, which targets EpCAM, at the American ... data at the AACR meeting indicating that its BiTE antibody MT110 can direct T cells to eliminate ... an update to investors and analysts on its BiTE antibody pipeline and to review key AACR presentations. ...

PDL BioPharma Elects Barry Selick to Its Board of Directors

... as we seek to maximize the value of our antibody humanization patents and related assets and ... underlying the creation of fully humanized antibody therapeutics and applied this technology to PDL's ... PDL is focused on maximizing the value of its antibody humanization patents and related assets. The ...

PDL BioPharma Announces Second Quarter 2009 Financial Results

... PDL is focused on maximizing the value of its antibody humanization patents and related assets. The ... royalties on sales of a number of humanized antibody products marketed today and also may receive royalty payments on additional humanized antibody products launched before patent expiry in late ...

Immune responses to flu vaccine are diminished in lupus patients

... safe and do not increase disease activity. Both antibody and cell-mediated responses are involved in the immune response to influenza; in SLE, antibody responses to the vaccine are diminished, but it ... vaccination. Previous studies have shown that antibody production following flu vaccination is lower in ...

PDL BioPharma to Announce Second Quarter 2009 Financial Results and Hold Conference Call July 30, 2009

... PDL is focused on maximizing the value of its antibody humanization patents and related assets. The ... royalties on sales of a number of humanized antibody products marketed today and also may receive royalty payments on additional humanized antibody products launched before patent expiry in late ...

Amgen Announces KRAS Safety Update to U.S. Prescribing Information for Vectibix(R) (Panitumumab)

... colorectal cancer (mCRC) treated with anti-EGFr antibody was discussed. "We are pleased that the ... of KRAS as a predictive biomarker for anti-EGFr antibody therapy," said Sean Harper, M.D., chief medical ... respond to monotherapy with an EGFr-inhibiting antibody (the Vectibix "408" trial). "With this ...

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Antibody in Medical Technology

Vectibix(R) in Combination With Chemotherapy Significantly Improved Progression-Free Survival in First-Line Metastatic Colorectal Cancer

... event profile was as anticipated for an anti-EGFR antibody in combination with oxaliplatin-based ... oxaliplatin-based chemotherapy and an anti-EGFR antibody are combined. "Our study underscores the ... leading to cancer progression. Anti-EGFR antibody therapies work by blocking the activation of ...

Researchers Create First Targeted Knockout Rats Using Zinc Finger Nuclease Technology

... company developing a new rat-based human antibody platform, used Sangamo's ZFNs to knock out the ... immunoglobulin M (IgM), an important gene for rat antibody production. Inactivation of rat IgM expression ... of the paper. "Inactivation of endogenous rat antibody expression is essential for ...

AlphaVax Announces Results from Initial Testing of Its H1N1 (Swine) Influenza Vaccine

... of an adjuvant, and they raise not only strong antibody responses but robust cellular responses, both of ... dose-dependent hemagglutination inhibition ("HI") antibody responses. After just a single dose of the H1N1 vaccine, all vaccinated animals developed HI antibody levels considered to be protective. These ...

MacroGenics and Lilly Achieve Targeted Patient Enrollment in PROTEGE, a Global Phase 2/3 Clinical Trial of Teplizumab in Type 1 Diabetes

... type 1 diabetes, is a humanized monoclonal antibody engineered to alter the function of the T ... set of capabilities in monoclonal antibody product development. The company's product ... lead program, teplizumab, is an anti-CD3 antibody being developed for the treatment of autoimmune ...

Tolerx Presents Data at 69th Scientific Sessions of the American Diabetes Association

... entitled "Dose Ranging Studies of an Anti-CD3 antibody in NOD mice to Determine Minimum Effective Dose," ... dosing regimens of the anti-CD3 monoclonal antibody in a commonly used non-obese diabetic (NOD) mouse ... Otelixizumab is a novel monoclonal antibody being developed for the treatment of type 1 ...

Micromet's Blinatumomab Achieves Primary Endpoint in Phase 2 Study with Acute Lymphoblastic Leukemia Patients

... presented phase 2 clinical data of the BiTE(R) antibody blinatumomab (MT103) at the 14th Congress of the ... (MRD)(1). Blinatumomab is a novel therapeutic antibody that activates a patient's T cells to seek out ... antibodies generated with its proprietary BiTE(R) antibody platform, as well as conventional monoclonal ...

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Antibody in Medical Products

Testosterone EIA kit

Description:... from binding proteins, making it available for antibody binding. Testosterone then equilibrates with an anti-Testosterone antibody linked to fluorescein isothiocyanate (FITC) and ... phosphatase labelled Testosterone. An anti-FITC antibody bound to magnetic particles then separates the ...
Company:Immunometrics

Antigen-Antibody Pen For Hamster Primary antibodies

Description:... are processed as usual with the appropriate 2-ab antibody conjugates, and ECL: results recorded on films or ... Therefore, if one is using rabbit primary antibody and the antigen pens specific for rabbit, then the secondary antibody must be anti-rabbit for the Antigen-antibody pens ...
Company:Alpha Diagnostic International, Inc.

Antigen-Antibody Pen For Rabbit Primary antibodies

Description:... are processed as usual with the appropriate 2-ab antibody conjugates, and ECL: results recorded on films or ... Therefore, if one is using rabbit primary antibody and the antigen pens specific for rabbit, then the secondary antibody must be anti-rabbit for the Antigen-antibody pens ...
Company:Alpha Diagnostic International, Inc.

Antigen-Antibody Pen For Sheep Primary antibodies

Description:... are processed as usual with the appropriate 2-ab antibody conjugates, and ECL: results recorded on films or ... Therefore, if one is using rabbit primary antibody and the antigen pens specific for rabbit, then the secondary antibody must be anti-rabbit for the Antigen-antibody pens ...
Company:Alpha Diagnostic International, Inc.

Antigen-Antibody Pen For Mouse Primary antibodies

Description:... are processed as usual with the appropriate 2-ab antibody conjugates, and ECL: results recorded on films or ... Therefore, if one is using rabbit primary antibody and the antigen pens specific for rabbit, then the secondary antibody must be anti-rabbit for the Antigen-antibody pens ...
Company:Alpha Diagnostic International, Inc.

Antigen-Antibody Pen For G. Pig Primary antibodies

Description:... are processed as usual with the appropriate 2-ab antibody conjugates, and ECL: results recorded on films or ... Therefore, if one is using rabbit primary antibody and the antigen pens specific for rabbit, then the secondary antibody must be anti-rabbit for the Antigen-antibody pens ...
Company:Alpha Diagnostic International, Inc.

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Antibody in Medical Definition

Medical procedure

... Insulin potentiation therapy Low-dose chemotherapy Monoclonal antibody therapy Photodynamic therapy Radiation therapy Targeted ... Pressure Wound Therapy Nicotine replacement therapy Monoclonal antibody therapy Oral rehydration therapy Insulin potentiation therapy ...

Central tolerance

... system • Inflammation • Complement system ( Classical , Alternative , Lectin , Anaphylatoxins ) • Cytokines • White blood cells • antibody ( Monoclonal antibodies , Autoantibody ) • Antigen • APC • MHC Immunity • Autoimmunity • Tolerance ( Central ) • ...

Pre-conditioning

... when and if the stimulus is encountered in the future. For example, a human may be exposed to artificially weakened virus in order to stimulate an antibody production in the body against that virus, so that later when the live 'wild-type' virus is countered, the body is immune or at least mounts an ...
Antibody in Medical Dictionary

Antibody

... antibody -dependent cell -mediated cytotoxicity: An immune response in which antibody , by coating target cells, makes them vulnerable to attack by immune cells. antibody -dependent cell -mediated cytotoxicity is ...

Antibody titer

... antibody titer Occasionally, the body makes an error and ... cell , or substance that is part of the body. antibody Titer The antibody level in the blood is a reflection of the ...

Antigen

... the accumulation of mutation s within the antibody -binding sites so that the resulting virus es ... some throbbing. Antigen leukocyte cellular antibody test (ALCAT). The practitioner draws samples of ... or hepatitis A virus test) and a positive antibody test (called an IgM anti -HAV ...

Ataxia

... ATTENUATED: Weakened or decreased. AUTO antibody : 1. An antibody that is active against some of the tissue s of the organ ism that produced it. 2. An antibody directed against the body's own tissue . ...

Complement

... and serve as the primary mediator in antigen - antibody reactions of the B cell mediated immune ... started in several ways, especially by antigen - antibody complexes. Alternative or Complement ary ... of events, usually triggered by an antigen - antibody complex, in which each component of the ...

ELISA

... ELISA Definition: A rapid test where an antibody or antigen is linked to an enzyme as a means of detecting a match between the antibody and antigen . ELISA tests are utilized to ... HIV infection by using two different types of antibody tests, ELISA and Western Blot. The first ...

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Antibody in Biological News

First human gets new antibody aimed at hepatitis C virus

... the safety and activity of a human monoclonal antibody they developed that can neutralize the Hepatitis ... virus (HCV). The first volunteer received the antibody known as MBL-HCV1 on July 28, 2009, and the study ... School. "This trial will test the safety of the antibody and measure its activity in the subjects. This ...

Antibody targeting of glioblastoma shows promise in preclinical tests, say Lombardi researchers

... have successfully tested a small, engineered antibody they say shuts down growth of human glioblastoma ... Oncogene, the researchers demonstrate how this antibody latches onto a receptor that studs the outside of ... metastasis of those cancers, suggesting that antibody treatment may be additionally useful in those ...

In vitro antibody production enables HIV infection detection in window period -- key to safer blood

... can be overcome, by in-vitro enhancement of antibody production (termed- Stimmunology). The results, ... Institute of Technology, ran the same HIV antibody tests using both regular plasma and SMART-plasma ... than HIV" In summary, in-vitro enhancement of antibody production, made simple by the SMARTube, has been ...

A quicker, cheaper SARS virus detector -- one easily customizable for other targets

... epidemics. It consists of a piece of synthetic antibody attached to a nanowire that's attached to an ... base, immersed in liquid. If the protein the antibody binds to is present in the liquid, it will bind ... containing residues randomly distributed over the antibody surface." The Zhou lab, which has specialized ...

Princeton team's analysis of flu virus could lead to better vaccines

... this multi-stage interactive process -- known as antibody interference -- to advantage, the scientists ... Academy of Sciences . "We have proposed that antibody interference plays a major role in determining the effectiveness of the antibody response to a viral infection," said Ned ...

Novel antibody prevents infection by hepatitis C virus

... School (UMMS) has developed a human monoclonal antibody that neutralizes the Hepatitis C virus (HCV). The new antibody effectively neutralized the virus in culture, and ... of pediatrics at the Medical School. "This antibody shows significant efficacy against the virus." ...

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Antibody in Biological Technology

Data Published in Cell Stem Cell Demonstrates Potent Anti-Cancer Activity for OncoMed Pharmaceuticals' Lead Antibody

... Inc., a clinical-stage company developing novel antibody therapeutics that target cancer stem cells, today ... and recurrence." OMP-21M18 is a monoclonal antibody that blocks DLL4 signaling to reduce tumor growth ... About OMP-21M18 OMP-21M18 is a monoclonal antibody optimized to block a key signaling pathway in ...

Micromet Closes $80.5 Million Public Offering of Common Stock

... antibodies generated with its proprietary BiTE(R) antibody platform, as well as conventional monoclonal ... are currently in clinical trials. Its BiTE antibody blinatumomab (MT103) is in a phase 2 clinical ... in many solid tumors. Micromet's human monoclonal antibody adecatumumab (MT201) also binds to EpCAM and is ...

Micromet Receives European Orphan Drug Designation for Treatment of Acute Lymphoblastic Leukemia with BiTE Antibody Blinatumomab

... the European Medicines Agency (EMEA) for BiTE antibody blinatumomab (MT103) for acute lymphoblastic leukemia (ALL). Blinatumomab is a novel therapeutic antibody that activates a patient's T cells to seek out ... antibodies generated with its proprietary BiTE(R) antibody platform, as well as conventional monoclonal ...

Micromet Announces Pricing of Public Offering of Common Stock

... antibodies generated with its proprietary BiTE(R) antibody platform, as well as conventional monoclonal ... are currently in clinical trials. Its BiTE antibody blinatumomab (MT103) is in a phase 2 clinical ... in many solid tumors. Micromet's human monoclonal antibody adecatumumab (MT201) also binds to EpCAM and is ...

Micromet Announces Public Offering of Common Stock

... antibodies generated with its proprietary BiTE(R) antibody platform, as well as conventional monoclonal ... are currently in clinical trials. Its BiTE antibody blinatumomab (MT103) is in a phase 2 clinical ... in many solid tumors. Micromet's human monoclonal antibody adecatumumab (MT201) also binds to EpCAM and is ...

PDL BioPharma to Present at BMO Capital Markets Healthcare Conference on August 5, 2009

... PDL is focused on maximizing the value of its antibody humanization patents and related assets. The ... royalties on sales of a number of humanized antibody products marketed today and also may receive royalty payments on additional humanized antibody products launched before patent expiry in late ...

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Antibody in Biological Products

Mycoplasma Testing and Decontamination from Covance Research Products, Inc

Description:... peptide synthesis and conjugation, polyclonal antibody production (rodents, guinea pigs, rabbits, ... and more), hybridoma development, monoclonal antibody production (in-vitro and in-vivo), serum, ascites, and spent media purification, antibody labeling, and custom packaging and ....
Company:Covance Research Products, Inc

Peptide Conjugation (OVA, BSA, KLH, Thyroglobulin) from Covance Research Products, Inc

Description:... peptide synthesis and conjugation, polyclonal antibody production (rodents, guinea pigs, rabbits, ... and more), hybridoma development, monoclonal antibody production (in-vitro and in-vivo), serum, ascites, and spent media purification, antibody labeling, and custom packaging and ....
Company:Covance Research Products, Inc

Embryonic Stem Cell Marker Antibody Panels from R&D Systems

Description:... R&D Systems adds two new Stem Cell antibody Panels to its expanding line of stem cell products. The Human Embryonic Stem Cell Marker antibody Panel (Catalog # SC008) contains the antibodies ... and SSEA-4. The Human Embryonic Stem Cell Marker antibody Panel Plus (Catalog # SC009) contains antibodies ...
Company:R&D Systems

Affinity Purification (antigen specific) from Covance Research Products, Inc

Description:... peptide synthesis and conjugation, polyclonal antibody production (rodents, guinea pigs, rabbits, ... and more), hybridoma development, monoclonal antibody production (in-vitro and in-vivo), serum, ascites, and spent media purification, antibody labeling, and custom packaging and ....
Company:Covance Research Products, Inc

Antibody Labeling: HRP, FITC, RITC, Biotin from Covance Research Products, Inc

Description:... peptide synthesis and conjugation, polyclonal antibody production (rodents, guinea pigs, rabbits, ... and more), hybridoma development, monoclonal antibody production (in-vitro and in-vivo), serum, ascites, and spent media purification, antibody labeling, and custom packaging and ....
Company:Covance Research Products, Inc

Isotyping from Covance Research Products, Inc

Description:... peptide synthesis and conjugation, polyclonal antibody production (rodents, guinea pigs, rabbits, ... and more), hybridoma development, monoclonal antibody production (in-vitro and in-vivo), serum, ascites, and spent media purification, antibody labeling, and custom packaging and ....
Company:Covance Research Products, Inc

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Antibody in Biological Definition

Antibody

... An antibody is a protein used by the immune system to ... objects like bacteria and viruses . Each antibody recognizes a specific antigen unique to its ... 1 Definition 2 Structure of the antibody 3 Isotypes 3.1 IgG 3.2 IgA 3.3 ...

Monoclonal antibody

... is a small piece of the antigen to which the antibody binds. Polyclonal antibodies bind to many ... capabilities are degraded. If the monoclonal antibody is susceptible to such degradation, it is ... conjugate or effector cell. In fact every intact antibody can bind to cell receptors or other proteins, ...

Immune system

... histocompatibility complex / class I MHC /class II MHC monoclonal antibody / polyclonal antibody ...

Molecular biology

... a protein are generated and are often then coupled to "beads". After the antibody has bound to the protein of interest, this antibody-protein complex can be ... proteins by centrifugation. During centrifugation, the beads, to which the antibody is coupled, will pellet (bringing the protein of interest down with it) ...

Semen

... a guinea pig with its own and foreign guinea pig sperm, finding that an antibody was produced in response; however the antibody was inactive, pointing to a suppression response by the immune system . ...

Affinity chromatography

... chromatography can be used in a number of applications, including nucleic acid purification, protein purification from cell free extracts and antibody purification from blood serum . Possibly the most common use of affinity chromatography is for the purification of recombinant proteins. ...

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Antibody in Biological Dictionary

Tubulin

... Controls >> Tubulin ... alpha Tubulin antibody - Loading Control. IHC-P, WB, ICC/IF. Rabbit ... ... microtubules. ... See below for alpha Tubulin antibody images, references, products ... Tubulin is ... (9F3) Rabbit mAb (green) ... 2148 α/β- Tubulin antibody ... 1032 β- Tubulin Blocking Peptide ... ...

Polyclonal Antibody

... of antibodies in vivo. ... Polyclonal antibody in Dictionary of Cell and Molecular Biology ... Pacific Immunology provides custom antibody production, polyclonal antibodies and immunochemistry services ... Polyclonal antibody production can be performed ... ... contract ...

Polyclonal antibodies

... epitope. Pacific Immunology provides custom antibody production, polyclonal antibodies and immunochemistry services ... Polyclonal antibody production can be performed ... Pacific Immunology provides custom antibody production, polyclonal antibodies and ...

MSH2

... as a mismatch repair protein, and ... MSH2 antibody - related products: Products for Western blot ... MSH2 (H-300) antibody sc-22771 MSH2 (H-300) antibody sc-22771 ... home " Tumor Suppressors/Apoptosis " ...

Monoclonal Antibody

... any substance, it is ... Monoclonal antibody therapy is the use of monoclonal antibodies ... is harvested from the mouse. ... Monoclonal antibody Production. A Report of the. Committee on ... a weeklong series of meetings ... Monoclonal antibody derived fragments are a nascent category of ...

Monoclonal

... is some method to ... Monoclonal antibody Production. A Report of the. Committee on Methods ... your webpage here ... There are many Monoclonal antibody treatments available ... Monoclonal antibody Therapy in Lymphoid Malignancies ... ...

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