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Affinity in Medical News

Caltech chemists say antibody surrogates are just a 'click' away

... can bind to a particular protein with very high affinity and selectivity, and that pass the following ... target protein, which means that both must have affinity for that protein; essentially, the protein itself ... molecules that bind selectively and with high affinity to particular proteins. I see no technical reason ...

Affinity VideoNet Partners With Providea Conferencing

... affinity VideoNet has teamed with Providea Conferencing, ... A/V integration, and video support services to affinity VideoNet clients and global room affiliates. ... Denver, CO and Camarillo, CA (PRWEB) July 8 -- affinity VideoNet has partnered with Providea Conferencing ...

Exclusive Marketplace for Nursing Professionals Launched by Nurses Service Organization

... June 1 /PRNewswire-FirstCall/ -- Aon affinity , a subsidiary of Aon Corporation (NYSE: ... catherine_schneider@asg.aon.com About Aon affinity Aon affinity combines the specialized knowledge ...

MMR Information Systems, Inc. Announces 250,000 Membership Milestone and Granting of International Patents

... company has an agreement to launch another major affinity membership program which is projected to bring ... have paid access through corporate benefits and affinity and membership group programs. MMR believes that ... acceptance as an employee benefit through affinity and membership groups, as a PHR through hospitals ...

MMR Information Systems, Inc. Joins With United Marketing Group to Offer Its MyMedicalRecords Personal Health Record and MyEsafeDepositBox Services to Vast Array of Nationally Recognized Partners

... fit into the direct marketing company's matrix of affinity merchandise offers and membership-based services. ... by doctors and hospitals and also through affinity and membership organizations. The company ... Group (UMG) is a leading direct marketer of affinity membership programs and merchandise products. ...

Also in the Jan. 27 JNCI

... cells. The researchers also modeled the relative affinity of ATP and imatinib for the mutant proteins using ... an isoleucine substitution had both a high enough affinity for ATP to promote cell growth and a low enough affinity for imatinib to be resistant to treatment. "We ...

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Affinity in Medical Technology

Anavex presents neuroprotective effects of Anavex 1-41 at the International Conference on Alzheimer's Disease 2008

... drug candidates demonstrate high, non-exclusive affinity for sigma receptors, which are involved in ... drug candidates exhibit high, non-exclusive affinity for sigma receptors with strong evidence for ... lead drug candidates exhibit high, non-exclusive affinity for sigma receptors with strong evidence for ...

Intra-Cellular Therapies Presents Data on Its Schizophrenia and Cognition in Schizophrenia Programs at the 14th Biennial Winter Workshop on Schizophrenia and Bipolar Disorders

... 5HT2A receptors with a 60-fold higher affinity for 5HT2A receptors over D2 receptors. In vivo, ... Additionally, ITI-007 was shown to have an affinity for the serotonin reuptake site, an activity ... histaminergic receptors and has a reduced affinity for adrenergic receptors relative to other ...

Dainippon Sumitomo Pharma Announces Lurasidone Phase III Data in Patients With Schizophrenia

... is a novel compound with a unique receptor-binding profile including high affinity for dopamine D(2), serotonin 5-HT(2A), 5-HT(7), 5-HT(1A), and noradrenalin alpha(2c) receptors. Lurasidone has low affinity for histamine H(1), and cholinergic M(1) receptors. About ...

RAPAFLO(TM) (silodosin) Provides Rapid and Sustained Benign Prostatic Hyperplasia (BPH) Symptom Relief in as Little as Three Days

... RAPAFLO(TM) maximizes target organ activity by binding with high affinity to the alpha (1A) receptors concentrated in the prostate. The antagonism ... in improved urine flow and a reduction in BPH symptoms. The binding affinity for the alpha (1B) receptors that cause smooth muscle in peripheral ...

Watson Announces United States Availability of RAPAFLO(TM) (silodosin), a Novel New Treatment in Benign Prostatic Hyperplasia (BPH)

... selective alpha-1 adrenergic receptor antagonist that binds with high affinity to the alpha 1a receptors concentrated in the prostate, bladder base and ... in improved urine flow and a reduction in BPH symptoms. The binding affinity for the alpha 1B receptors that regulate smooth muscle relaxation and ...

Access Pharmaceuticals Presents new Combination Data on the Company's Angiolix(R) Therapeutic Monoclonal Antibody

... antibody, Angiolix, which confirmed that Angiolix(R) binds with high affinity to the its target, lactadherin, resulting in anti-angiogenesis and ... which has considerable potential for the treatment of cancer through its affinity for a novel target, lactadherin. Lactadherin is an extracellular matrix ...

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Affinity in Medical Products

Affinity™ DC Pacemakers

Description:... The affinity pacemaker family offers some of today's smallest, truly automatic devices. ... the most effective combination of advanced technologies ever seen, the affinity DR pacemaker incorporates the exclusive ventricular AutoCapture Pacing ...
Company:St. Jude Medical, Inc.

Affinity™ VDR Pacemaker

Description:... The affinity pacemaker family offers some of today's smallest, truly automatic devices. ... the most effective combination of advanced technologies ever seen, the affinity DR pacemaker incorporates the exclusive ventricular AutoCapture Pacing ...
Company:St. Jude Medical, Inc.

Affinity™ SR Pacemakers

Description:... The affinity pacemaker family offers some of today's smallest, truly automatic devices. ... the most effective combination of advanced technologies ever seen, the affinity DR pacemaker incorporates the exclusive ventricular AutoCapture Pacing ...
Company:St. Jude Medical, Inc.

Affinity™ DR Pacemakers

Description:... The affinity pacemaker family offers some of today's smallest, truly automatic devices. ... the most effective combination of advanced technologies ever seen, the affinity DR pacemaker incorporates the exclusive ventricular AutoCapture Pacing ...
Company:St. Jude Medical, Inc.

Affinity DR 5330R

Description:... The affinity pacemaker family offers some of today's smallest, truly automatic devices. ... the most effective combination of advanced technologies ever seen, the affinity DR pacemaker incorporates the exclusive ventricular AutoCapture Pacing ...
Company:St. Jude Medical, Inc.

IGFBP-1, Total IRMA Test

Description:... differential phosphorylation of IGFBP-1 which may significantly alter its affinity for IGFs and, therefore, its capacity to modulate their cellular ... Non-phosphorylated IGFBP-1 has been shown to have 4- to 6-fold lower affinity for IGF-I compared with phosphorylated IGFBP-1 variants [7,9]. IGFBP-1 ...
Company:Diagnostic Systems Laboratories, Inc.

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Affinity in Medical Definition

Thymocyte

... induction of apoptosis in thymocytes with a high affinity for self peptides or MHC. This eliminates cells ... binding MHC class I or class II with even a weak affinity receive signalling through the T cell receptor. ... negative selection, all thymocytes with a high affinity for binding self peptides presented on MHC class ...
Affinity in Medical Dictionary

Leukemia

... I (HTLV-I): HTLV-I and HTLV-II, like all retrovirus es, are single-stranded RNA virus es that replicate through a DNA intermediate. HTLV-I has an affinity for T lymphocyte s; it appears to be the causative agent of certain T cell leukemia s, ... A high WBC count may indicate infection , ...

Passive

... to love them. But love doesn't work that way. To get love and keep love you have to go out and be active and learn a variety of specific skills. affinity oxygen atorOxygenator with specially treated heparin-coated Trillium bio passive surface for use in heart /lung bypass procedures. Mfg: Medtronic ...
Affinity in Biological News

Study reveals specific gene in adolescent men with delinquent peers

... statistically significant association between an affinity for antisocial peer groups and a particular ... and warmth) showed no statistically relevant affinity for antisocial friends. "Our research has ... his colleagues found no statistically significant affinity for antisocial peers, regardless of whether the ...

Hemoglobin uncovered

... knowledge of the mechanisms that regulate the affinity of hemoglobin, which is crucial to understand, ... how, against what was commonly accepted, the affinity for oxygen appears to be controlled by ... Having identified the factors that regulate the affinity of hemoglobin, alterations of its structure can ...

MIT model could improve some drugs' effectiveness

... to treat colorectal cancer, that binds to its target with 10 times greater affinity than the original molecule. The work, which will appear Sept. 23 in an ... antibody variants and conformations, and predict the molecules' binding affinity for their targets based on the interactions that occur between atoms. ...

Study explains potential failure of oral contraceptives with obese women

... "lipophilic," or tend to concentrate in fat tissue. However, the researchers in this study said they were somewhat surprised to find that the affinity of these drugs for fat tissue was not significantly different between obese and normal body weight subjects. Rather, the researchers found that ...

Biologist discovers pink-winged moth in Chiracahua Mountains

... of the noctuid family, which often are dull colored. Walsh's moth, in contrast, is bright pink. He also named it after his wife, Lee, who has an affinity for the color. Walsh discovered L. leeae while collecting one evening at Onion Saddle, at about 7,700 feet in the Chiracahuas. Collecting ...

American Society for Microbiology honors George Liu

... graduate work was the investigation of the mechanism of immunologic tolerance in a model of autoimmunity. His novel concept that the low affinity of certain autoantigenic peptides could provide a basis for the existence of autoreactive T cells in humanshad an impact on the field of ...

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Affinity in Biological Technology

ProMetic signs $35 M Long-term Supply Agreement with European Biopharmaceutical company

... provide access to one of ProMetic's proprietary affinity adsorbents for incorporation into this company's ... growth in the demand for ProMetic's proprietary affinity adsorbents," commented Dr. Steve Burton, PBL's ... Agency are now manufactured using ProMetic's affinity adsorbent products," stated Mr. Pierre Laurin, ...

Telik Presents Preclinical Data at 99th Annual Meeting of the American Association for Cancer Research

... Through the use of Telik's Target-Related affinity Profiling (TRAP(R)) screening technology, novel ... anti-tumor activity in vitro. Target-Related affinity Profiling (TRAP(R)): Efficient Cancer ... based on a unique molecular descriptor called an affinity fingerprint. An ...

Anavex appoints Dr. Dimitri Goundis to lead Clinical Development

... drug candidates demonstrate high, non-exclusive affinity for sigma receptors, which are involved in the ... The company's lead drug candidates exhibit high affinity for sigma receptors with strong evidence for ... The company's lead drug candidates exhibit high affinity for sigma receptors with strong evidence for ...

ProMetic to obtain controlling stake in Pathogen Removal and Diagnostic Technologies Inc.

... from human red blood cells with prion protein affinity ligand. Transfusion 2006; 46:1152-1161 Wroe SJ, ... and characterization of novel membrane filter affinity media for protein adsorption. Dr. Carbonell is ... in the development and manufacture of robust affinity separation materials which provide very ...

Anavex 7-1037 reduces rate of cancer tumor growth 69% in pre-clinical studies, compared to currently marketed drug Dacarbazine showing no measurable activity

... has been previously reported to exhibit high affinity for sigma-1 (nanomolar) receptors and moderate (micromolar) affinity for sigma-2 receptors and sodium channels. In ... drug candidates demonstrate high, non-exclusive affinity for sigma receptors, which are involved in the ...

MIT explains spread of 1918 flu

... Two mutations dramatically change the HA binding affinity to receptors found in the human upper airways, ... HA allow flu viruses to bind tightly or with high affinity to the umbrella-shaped glycan receptors. The affinity between the influenza virus HA and the glycan ...

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Affinity in Biological Products

ImmunoPure IgM Purification Kit from Pierce Biotechnology, Inc.

Description:... A and, until recently, no readily available affinity chromatography product existed for one- step IgM ... samples. Pierce has developed an easy-to-use affinity matrix and buffer system to purify IgM. This ... IgM can be obtained from a single pass over the affinity column. Human IgM will bind to the support and ...
Company:Pierce Biotechnology, Inc.

Polyclonal Antibody Production from Agro-Bio

Description:... test Antibody purification on protein A/G or by affinity on antigen Chickens are an excellent host for ... conjugation ELISA test Antibody purification by affinity on antigen in order to obtain specific IgY ... test Antibody purification on protein A/G or by affinity on ...
Company:Agro-Bio

Immobilized Metal affinity ProteinChip Arrays from Ciphergen

Description:... ProteinChip arrays have been developed for affinity capture of proteins from biological samples. A ... proteins directly on the chip. Immobilized metal affinity capture (IMAC) arrays bind proteins and peptides which have affinity for metals; proteins with exposed histidine, ...
Company:Ciphergen

IMPACT-CN System from New England Biolabs

Description:... IMPACT (Intein Mediated Purification with an affinity Chitin-binding Tag) utilizes the inducible ... to purify recombinant proteins by a single affinity column (1-4) (Figures 1 and 2). This system ... to separate a recombinant protein from the affinity tag without the use of a protease. The ...
Company:New England Biolabs

Multiple Affinity Removal System from Agilent Technologies

Description:... without interferences. The Agilent Multiple affinity Removal System allows you to remove unwanted, ... and MD-HPLC Go beyond the limitations of other affinity columns Expand the dynamic range of current ... and hardware/software, the Agilent Multiple affinity Removal System creates an automated, integrated ...
Company:Agilent Technologies

Custom Antibody Production Services from Aves Labs, Inc.

Description:... quantities of IgY (or tens of gram quantities of affinity purified antibodies) to meet your specifications ... fractions from eggs collected from these hens and affinity purifying the antibodies against immunosorbent materials. Labeling the affinity purified antibodies with biotin, HRP, fluorescent ...
Company:Aves Labs, Inc.

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Affinity in Biological Definition

Affinity chromatography

... affinity chromatography is a biochemical separation ... 2 Specific Uses 3 Batch verses column 4 affinity Chromatography Protocols General ... property which can be exploited during the affinity purification process. The process itself can be ...

Allostery

... to assume the R state, thereby enhancing their affinity for substrate. Sequential model The ... substrate binding causes increased substrate affinity in adjacent subunits Allosteric activation ... when the binding of one ligand decreases the affinity for substrate at other active sites. For example, ...

Allostery

... to assume the R state, thereby enhancing their affinity for substrate. Sequential model The ... substrate binding causes increased substrate affinity in adjacent subunits Allosteric activation ... when the binding of one ligand decreases the affinity for substrate at other active sites. For example, ...

Chromatography

... chromatography 7 Immobilized metal ion affinity chromatography 8 High performance liquid ... 9 Gel permeation chromatography 10 affinity chromatography 11 See also 12 External ... as stationary phase. Immobilized metal ion affinity chromatography IMAC is a popular and powerful ...

Signal transduction

... . Most extracellular chemical signals have affinity for water and are unable to penetrate the oily ... which they are able to do because of a partial affinity for oily surroundings (see hydrophobic ). ... complex, which is defined by the affinity of the hormone for the receptor, the ...

Polymerase chain reaction

... or enzymes in biological washing powders. The incorporation of an affinity tag on a recombinant protein will generate a fusion protein which can be more easily purified by affinity chromatography . Figure 5 : Cloning a gene using a plasmid. (1) ...

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Affinity in Biological Dictionary

Streptavidin

... biology through its extraordinarily strong affinity for biotin ; the dissociation constant (Kd) of ... found in Streptomyces griseus which has a high affinity for biotin and is used ... structure of a ... Home > Ig/2nd Step > Streptavidin ... affinity purified streptavidin can be supplied in batch ...

His tag

... ( His tag ) ... ... Tag Purification. affinity Tag Purificaton Columns. His Tag ... His - ... Purification ColumnSpin FormatHIS-Buster Cobalt affinity Gel is a ... ... Kits " His Tag ... " Protein Biochemistry " Protein Purification " affinity Tag ... his - tag . Dictionary terms for ...

Affinity chromatography

... affinity chromatography is a method of separating ... enzyme and substrate, or receptor and ligand. affinity ... Chromatography is the collective term ... phase, which separates the analyte ... affinity chromatography is a method that overcomes this ...

Fusion Protein

... with functional properties derived from each of ... The Tandem affinity Purification (TAP) is a technique for studying protein - protein ... (Fluc) fusion protein was transiently transfected into ... affinity purification of GST fusion proteins ... PopCulture extraction and ...

Epitope

... ... Deciphering epitope specificities within polyserum using affinity selection of ... Generation, Characterization and Epitope Mapping of ... ... Specializing in the production of polyclonal antibodies, antisera, affinity purified antibodies, fluorescein and ... Epitope Tags. Secondary ...

Band shift assay

... assay , band shift assay , or gel retardation assay , is a common affinity electrophoresis technique used ... ETH Zuerich ... by band - shift ... ... The procedure described in this chapter for the determination of affinity constants and kinetic dissociation constants by band - shift assay ...

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Other Contents
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Breaking Medicine News(10 mins):Health News:Medical Solutions Co-Founder/CFO Scott Anderson Named to Staffing Industry Analysts’ 2014 Staffing 100 2Health News:Medical Solutions Co-Founder/CFO Scott Anderson Named to Staffing Industry Analysts’ 2014 Staffing 100 3Health News:Shriners Hospitals for Children - Lexington Announces Plan to Build New $47 Million Facility 2Health News:Shriners Hospitals for Children - Lexington Announces Plan to Build New $47 Million Facility 3Health News:Best Cheap Hosting USA Has Recently Announced The Best Cheap Web Hosting Companies In 2014 2Health News:Rich Carlson and Marc Duey to Hold Workshop at CBI’s Specialty Pharmacy and Distribution Networks Conference 2Health News:Binge Drinking May Boost Blood Pressure in Young Men 2Health News:Binge Drinking May Boost Blood Pressure in Young Men 3Health News:Binge Drinking May Boost Blood Pressure in Young Men 4
(Date:10/15/2014)... Geneticist Fred Alt will be awarded the 44th Rosenstiel ... University for his pioneering research exploring the mechanisms of ... and cancer cells. Alt is the second alumnus to ... the Nobel Prize in 2003. , Alt is the ... Genetics at Harvard Medical School and an investigator at ...
(Date:10/14/2014)... new study published in Cancer Research shows ... and colon cancers—can promote the development of skin cancers ... and survival of sun-damaged skin cells. , Previously considered ... proteins called sirtuins that help regulate genomic stability and ... SIRT6 helps repair DNA damage, which can lead to ...
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Breaking Biology News(10 mins):Brandeis awards 44th Rosenstiel Award to pioneering geneticist Fred Alt 2Two-faced gene: SIRT6 prevents some cancers but promotes sun-induced skin cancer 2Building a bridge from basic botany to applied agriculture 2Building a bridge from basic botany to applied agriculture 3
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