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adenosine in Medical News

Prune juice not necessary: New research should make bowel movements easier

... present on human nerves in the gut (a type of adenosine receptor). The first group of mice had normal adenosine receptors on these nerves and normal bowel ... The second group of mice completely lacked these adenosine receptors and showed familiar signs of ...

Cordex Pharma Submits to the FDA an Amended Special Protocol Assessment for ATPace

... is an investigational stable formulation of adenosine 5'-triphosphate (ATP) administered by intravenous ... treatments for PSVT. Currently, adenosine is the only approved drug for the acute treatment ... more efficacious than the initial labeled dose of adenosine in terminating PSVT. While both ATP ...

JCI online early table of contents: Feb. 16, 2009

... METABOLIC DISEASE: adenosine signaling links alcohol and liver disease ... liver in mice. Further analysis revealed that adenosine mediated its effects in mice via two proteins, the adenosine A1 and A2B receptors. The authors therefore ...

Support cells, not neurons, lull the brain to sleep

... of compensating. Prior studies pointed to adenosine as a trigger for sleep pressure. The chemical ... the dnSNARE transgene, to block the release of adenosine and other chemicals from astrocytes. The ... used certain compounds to block the effects of adenosine on neurons. Neurons have several types of ...

Duska Therapeutics and DSM Pharmaceuticals in Manufacturing Collaboration for PSVT Drug Product

... ATPace, a stable liquid formulation of adenosine 5'-triphosphate (ATP) for intravenous injection, ... in the United States alone. Currently, adenosine is the only approved treatment for PSVT in ... adenosine in terminating PSVT. While both ATP and adenosine inhibit atrio-ventricular nodal conduction, ATP ...

Duska Therapeutics Receives Comments From FDA on Phase 3 ATPace(TM) Protocol Synopsis

... drug for the acute treatment of PSVT." ATPace, adenosine triphosphate injection, is a proposed drug for the termination of PSVT. The bradycardic effect of adenosine triphosphate, in particular its blockade of ... PSVT in the United States alone. Currently, adenosine is the only approved treatment for PSVT in ...

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adenosine in Medical Technology

Cordex Signs European Development Partnership for ATPotent(TM) Sperm Motility Drug

... proprietary technologies related to the use of adenosine 5'-triphosphate (ATP) for improving human and ... animal sperm, in which the active ingredient is adenosine 5'-triphosphate (ATP). ATP is a ubiquitous purine ... medicines based upon the emerging pharmacology of adenosine triphosphate (ATP) and nitric oxide (NO). These ...

Cordex Pharma Announces Strategic Master Services Equity Agreement With Cato BioVentures

... is an investigational stable formulation of adenosine 5'-triphosphate (ATP) administered by intravenous ... efficacious treatments for PSVT. Currently, adenosine is the only approved drug for the acute treatment ... more efficacious than the initial labeled dose of adenosine in terminating PSVT. While both ATP ...

Duska Therapeutics Applies for Phase 3 Special Protocol Assessment

... ATPace, a stable liquid formulation of adenosine 5'-triphosphate (ATP) for intravenous injection, ... treatments for PSVT. Currently, adenosine is the only approved treatment for PSVT in the ... efficacious than the initial labeled dose of adenosine in terminating PSVT. While both ATP ...

Three Independent Studies Include the ImmuKnow(R) Assay to Manage and Optimize Immunosuppression Therapy in Transplant Patients

... that assesses cellular immune status by detecting cell-mediated immunity (CMI) in adult immunosuppressed patients. It measures the concentration of adenosine triphosphate (ATP) released from CD4 cells following cell stimulation. The ImmuKnow test is a qualitative assay and does not directly quantify the ...

Living Donor Kidney Transplants Using Alemtuzumab Pre-Conditioning and Tacrolimus Monotherapy: Long-Term Safety and Efficacy

... that assesses cellular immune status by detecting cell-mediated immunity (CMI) in adult immunosuppressed patients. It measures the concentration of adenosine triphosphate (ATP) released from CD4 cells following cell stimulation. The ImmuKnow test is a qualitative assay and does not directly quantify the ...

New Analysis Evaluated Impact of Genetic Variation on Response to Prasugrel

... with acute coronary syndromes undergoing PCI. Prasugrel works by inhibiting platelet activation and subsequent aggregation by blocking the P2Y12 adenosine diphosphate (ADP) receptor on the platelet surface. Antiplatelet agents prevent platelets from clumping or sticking together, which can result in ...
adenosine in Medical Products

VACUETTE CTAD Tubes - Ridged (safety screw cap)

Description:... CTAD tubes contain theophylline, adenosine and dipyridamol. Coagulation and DTAD tubes are for examination of coagulation ....
Company:Greiner Bio-One

Autologous Platelet Gel

Description:... and functional changes involved in coagulation take place. Secreted from the platelets are a number of factors including serotonin, fibronectin, adenosine diphosphate, thromboxane A, platelet factor 4, platelet derived growth factor and platelet activating factor. Release of these factors cause a ...
Company:Blood Recovery Systems, Inc.
adenosine in Medical Dictionary

Deficiency

... Pulmonary Pertaining to the lungs . ADA deficiency is a rare genetic disease . The normal ADA gene produces an enzyme called adenosine deaminase, which is essential to the body’s immune system . Iron- deficiency anaemia is the most common form of anaemia. In the United ...

Gene Therapy

... Anderson, R. Michael Blaese and Kenneth W. Culver who infused genetic ally engineered blood cells to repair an immune deficiency disorder: adenosine deaminase (ADA) deficiency . angiogenic gene therapy treatment Investigational treatment delivers a growth factor gene to disease d ...

Intracellular

... and evaluate the response of the heart tissue s to treatment s. ^ Top ... Protein kinase A: An enzyme system that is activated by cyclic adenosine monophosphate (cAMP) and that catalyzes the activity of intracellular protein s. There are two isozymes of protein kinase A, type I and type II. ...

Myocardial Infarction

... deprivation of circulating blood . AMISTAD ( acute myocardial infarction study of adenosine) Study to determine the efficacy of intravenous adenosine in combination with either streptokinase or tPA ( tissue plasminogen activator) in limiting the size of myocardial infarct s. Myocardial ...

Protein

... cells. With kidney failure , your child will need to avoid excess protein . Protein kinase A: An enzyme system that is activated by cyclic adenosine monophosphate (cAMP) and that catalyzes the activity of intracellular protein s. There are two isozymes of protein kinase A, type I and type II. ...

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adenosine in Biological News

UT Southwestern researchers identify molecule that helps the sleep-deprived to mentally rebound

... with mice, they found that a molecule called an adenosine receptor is necessary for sleep-restricted ... at UT Southwestern. "We need to have our adenosine receptors intact to do that." adenosine receptors on nerve cells, including brain cells, ...

Jefferson receives $11.6M NIH grant to study novel mechanisms of heart failure

... Medical College, will focus on the role of adenosine receptors in the heart. While much is known about ... after injury and in heart failure. Two major adenosine receptor types in the heart appear to have ... research team wants to more closely study the adenosine receptors in the failing heart. Steven R. ...

A little java makes it easier to jive, researcher says

... Early in his research, he became aware that "caffeine works on the adenosine neuromodulatory system in the brain and spinal cord, and this system is ... in nociception and pain processing." Since Motl knew caffeine blocks adenosine from working, he speculated that it could reduce pain. A number of ...

Biosensing nanodevice to revolutionize health screenings

... living things, including photosynthesis in plants. F1-ATPase breaks down adenosine triphosphate (ATP) to adenosine diphospahte (ADP), releasing energy. Previous studies of its structure and ...

Building memories with actin

... changes. Rex et al. tackled the question by dosing slices of rat hippocampus with adenosine, a naturally occurring signal that squelches LTP. adenosine prevents phosphorylation and inactivation of cofilin, an inhibitor of actin filament assembly, the team found. Cofilin's involvement, in turn, ...

Protein regulates movement of mitochondria in brain cells

... understanding how the brain responds to a pathological state." Mitochondria are cellular power plants that generate most of the cell's supply of adenosine triphosphate (ATP), which is used as a source of chemical energy. While mitochondria are present in all of the body's cells, some cells because of ...

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adenosine in Biological Technology

PeriCor Therapeutics Reports Positive Preclinical Results of GP531 at the European Heart Failure Congress in Nice

... adenosine Regulation with GP531 Improves the Heart's ... The study entitled "Intravenous GP531, an adenosine Regulating Agent, Improves Left Ventricular ... new class of cardioprotective compounds known as adenosine regulating agents (ARAs). ARAs, including GP531, ...

Duska Therapeutics Submits Phase 3 ATPace(TM) Protocol to FDA for Comment

... terminate re-entrant PSVT involving the AV node. adenosine is the only approved competition in the U.S. ... of adenosine in terminating PSVT. While ATP and adenosine both inhibit AVN conduction, ATPace(TM) is ... based upon the emerging new pharmacology of adenosine triphosphate (ATP) and nitric oxide (NO). These ...

Astellas Launches Lexiscan(TM) (Regadenoson) Injection for Use as a Pharmacologic Stress Agent in Radionuclide Myocardial Perfusion Imaging (MPI)

... -First A2A adenosine Receptor Agonist Approved for Use in Identifying ... of Lexiscan(TM) (regadenoson) injection, an A2A adenosine receptor agonist, for use as a ... Therapeutics (Nasdaq: CVTX ), is the first A2A adenosine receptor agonist shown to be safe and effective ...

Commercial Launch of Lexiscan(TM) (Regadenoson) Injection Triggers $10 Million Milestone Payment from TPG-Axon Capital to CV Therapeutics

... Lexiscan(TM) (regadenoson) injection, an A2A adenosine receptor agonist, for use as a pharmacologic ... (regadenoson) injection Lexiscan(TM) is an A2A adenosine receptor agonist approved for use as ... coronary blood flow by activation of the A2A adenosine receptor. Lexiscan(TM) is administered as a rapid ...

CV Therapeutics Announces $185 Million Transaction with TPG-Axon Capital for Half of Royalty for Lexiscan(TM) (regadenoson) Injection

... Lexiscan(TM) (regadenoson) injection, an A2A adenosine receptor agonist, for use as a pharmacologic ... The product has been designed to target the A2A adenosine receptor, which is the adenosine receptor subtype responsible for coronary ...

CV Therapeutics and Astellas Announce FDA Approval for Lexiscan(TM) (regadenoson) Injection

... -First A2A adenosine Receptor Agonist Approved for Use as ... (regadenoson) injection, an A2A adenosine receptor agonist, for use as a pharmacologic ... exercise stress. Lexiscan is the first A2A adenosine receptor agonist shown to be safe and effective ...

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adenosine in Biological Products

Adenosine 5'-triphosphate (ATP) Luminescence Assay Kit from Thermo Scientific

Description:... The ATP Monitoring Kit measures adenosine triphosphate (ATP) concentrations with high sensitivity and a dynamic range. Based on the bioluminescence technique, the assay measures ATP in ...
Company:Thermo Scientific
adenosine in Biological Definition

Adenosine triphosphate

... ATP, see ATP (disambiguation) adenosine triphosphate ( ATP ) is the nucleotide known ... properties Chemically, ATP consists of adenosine and three phosphate groups. It has the ... hydrolysis yields free inorganic phosphate and adenosine diphosphate , which can be broken down further to ...

ATPase

... enzymes that catalyze the decomposition of adenosine triphosphate (ATP) into adenosine diphosphate (ADP) and a free phosphate ion . ... an inorganic phosphate group to a molecule of adenosine diphosphate (ADP) to form a molecule ...

Nucleoside

... Deoxynucleoside Adenine adenosine A Deoxyadenosine dA Guanine ... Examples of these include cytidine , uridine , adenosine , guanosine , thymidine and inosine . ... Nucleobase Nucleotide DNA RNA adenosine triphosphate (ATP) ...

Nucleotide

... Chemical structures Nucleotides adenosine monophosphate AMP adenosine diphosphate ADP adenosine triphosphate ATP Guanosine monophosphate ...

AMP

... AMP can refer to the following: In biology , the nucleotide adenosine monophosphate As a flavour enhancer , the nucleotide adenosine monophosphate AngryMutantPenguin, a famous fan of The Elder Scrolls ...

ATP synthase

... ( EC 3.6.3.14) is a general term for an enzyme that can synthesize adenosine triphosphate (ATP) from adenosine diphosphate (ADP) and inorganic phosphate by utilizing some form of ...

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adenosine in Biological Dictionary

RNA editing

... not listed here or ... RNA editing by adenosine (A) to inosine (I) ... RNA editing of micro ... for the continued survival of the ... adenosine (A) to inosine (I) RNA editing occurs widely ... by Combinatorial Chemistry ... An RNA - editing adenosine ... ...

Nucleotide

... triphosphate, ATP — a nucleotide derived from adenosine ... A nucleotide is a chemical compound ... in the free online English dictionary and ... adenosine triphosphate, ATP - a nucleotide derived from adenosine that occurs in ... Encyclopedia information ...

Adenosine triphosphate

... adenosine -5'- triphosphate (ATP) is a multifunctional ... transfer. In this role, ... ATP ( ) n. An adenosine -derived nucleotide, C 10 H 16 N 5 O 13 P 3 , that ... adenosine -5'- triphosphate (ATP) is a multifunctional ...

Adenosine diphosphate

... adenosine diphosphate , abbreviated ADP, is a nucleotide. ... of pyrophosphoric acid with the nucleoside adenosine . ADP consists of the pyrophosphate group, the ... the nucleobase adenine. Aspects of the topic adenosine - diphosphate are discussed in the following ...

Adenosine deaminase

... adenosine deaminase is an enzyme (EC 3.5.4.4) involved ... metabolism. It is needed for the breakdown of adenosine from food and for the turnover of nucleic acids in tissues. double-stranded RNA adenosine deaminase activity. • zinc ion binding. • ...

Adenosine

... adenosine is a nucleoside composed of a molecule of ... moiety via a β-N9-glycosidic bond. The adenosine A2A receptor, also known as ADORA2A, is an adenosine receptor, but also denotes the human gene ...

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