Navigation Links
Positive Results Prompt US National Cancer Institute to Make,Gleevec Available To Patients in Post-Surgical Gist Study

- Gleevec found to dramatically reduce the risk of cancer returning after surgery for Kit-positive gastrointestinal stromal tumors (GIST)

EAST HANOVER, N.J., April 12, 2007 /PRNewswire/ -- Investigators will begin offering Gleevec(R) (imatinib mesylate)* tablets to patients receiving placebo in a major North American clinical trial after an interim analysis showed participants with Kit-positive gastrointestinal stromal tumors treated with Gleevec following surgery were significantly less likely to experience a return of their cancer compared to those not taking this innovative therapy.

The interim analysis showed no recurrence of cancer in approximately 97% of patients given Gleevec for a year after surgery to remove tumors, compared to approximately 83% of those who underwent surgery but received a placebo. The investigators made these results public because the study had met its primary endpoint in terms of rate of recurrence-free survival.

The study involving more than 600 patients was sponsored by the National Cancer Institute (NCI), part of the US National Institutes of Health (NIH). It was conducted at multiple cancer centers in the US and Canada, and was led by the of Surgeons Oncology Group. Novartis supplied Gleevec for use in the study, and also provided partial funding under a Cooperative Research and Development Agreement with NCI to support the clinical development of Gleevec.

Gleevec has already been confirmed as an effective therapy in its approved use for patients with advanced metastatic or unresectable (inoperable) Kit- positive GIST. In a statement issued today by the NIH, the new findings were heralded as excellent news, with major implications for patients with primary disease.

"With these new data, we see that Gleevec may help patients with early GIST," said Diane Young, MD, Head of Global Medical Affairs at Novartis Oncology. "We will now work with the investig
'"/>




Page: 1 2 3 4 5 6 7

Related medicine technology :

1. Neose Announces Presentation of Positive Preclinical Data on GlycoPEGylated Factor VIIa at the XXI Congress of the International Society on Thrombosis and Haemostasis
2. Positive Aggrastat Results Featured in the Journal of the American College of Cardiology
3. Portola Pharmaceuticals Announces Positive Data from a Phase II Study of its Factor Xa Inhibitor at the XXI Congress of the International Society on Thrombosis and Haemostasis
4. Protox Announces Positive Clinical Data from Prostate Cancer Study
5. AM-Pharma Announces Positive Results of Phase IIa Clinical Trial with Alkaline Phosphatase For Ulcerative Colitis
6. Cougar Biotechnology Announces Presentation of Positive CB7630 Clinical Data at ESMO Conference
7. TransPharma Medical Announces Positive Results of Phase I Clinical Trials for Transdermal Delivery of hPTH (1-34) for Osteoporosis Treatment
8. Positive ZIO-201 Interim Phase II Sarcoma Data Presented at European Society for Medical Oncology
9. Cosmo Pharmaceuticals Reports Positive Preliminary Phase II/III Data with Rifamycin MMX in Infectious Diarrhea
10. Portola Pharmaceuticals Announces Positive Phase II EXPERT Results and Additional Oral and Poster Presentations at the XXI Congress of the International Society on Thrombosis and Haemostasis (ISTH)
11. Chi-Med Announces Positive Phase II Proof-of-Concept Data for HMPL-004 in Ulcerative Colitis
Post Your Comments:
(Date:3/30/2015)... and BRISBANE, Calif., March 30, 2015 Shareholder ... the proposed acquisition of Hyperion Therapeutics, Inc. (NASDAQ: ... HZNP ).  On March 30, 2015, the two companies ... to which Horizon will acquire Hyperion.  Under the terms ... cash for each share of Hyperion common stock. ...
(Date:3/30/2015)... Va. , March 30, 2015  Researchers ... the Marshall University Joan C. Edwards School of ... entitled, "PSEN1 Variant in a Family with Atypical ... genetically confirmed to have a known variant of ... drug Bryostatin 1. Genetically confirmed Alzheimer,s patients as ...
(Date:3/30/2015)... -- The investigational S- equol nutritional supplement may be ... as hot flashes, according to a new peer-reviewed article ... "Current data suggest that women may have ... and possibly additional benefits, such as skin health. Given ... and health care professionals may consider the use of ...
Breaking Medicine Technology:Robbins Arroyo LLP: Acquisition of Hyperion Therapeutics, Inc. (HPTX) by Horizon Pharma plc (HZNP) May Not Be in Shareholders' Best Interests 2Robbins Arroyo LLP: Acquisition of Hyperion Therapeutics, Inc. (HPTX) by Horizon Pharma plc (HZNP) May Not Be in Shareholders' Best Interests 3Severe Alzheimer's Patient Responds to Bryostatin Treatment 2Severe Alzheimer's Patient Responds to Bryostatin Treatment 3Severe Alzheimer's Patient Responds to Bryostatin Treatment 4Severe Alzheimer's Patient Responds to Bryostatin Treatment 5New Scientific Review Suggests Some Women May Benefit from Considering Use of S-equol to Ease Menopause Symptoms 2New Scientific Review Suggests Some Women May Benefit from Considering Use of S-equol to Ease Menopause Symptoms 3New Scientific Review Suggests Some Women May Benefit from Considering Use of S-equol to Ease Menopause Symptoms 4New Scientific Review Suggests Some Women May Benefit from Considering Use of S-equol to Ease Menopause Symptoms 5New Scientific Review Suggests Some Women May Benefit from Considering Use of S-equol to Ease Menopause Symptoms 6
... June 6, 2012 /PRNewswire-iReach/ -- Particle ... in contamination monitoring.  Founded by Dr. Robert Knollenberg in ... company has grown to be the global leader in ... the U.S. including direct operations in Italy, Japan, China, ...
... Research Institute Professor Richard A. Lerner, MD, has won ... for Scientific and Technical Research, according to an announcement ... shares the award with British biochemist Sir Gregory Winter, ... the Prince of Asturias Award for Scientific and Technical ...
Cached Medicine Technology:Particle Measuring Systems® Celebrates 40 Years of Leadership 2Scripps Research Institute's Richard A. Lerner Wins Prince of Asturias Award for Scientific and Technical Research 2Scripps Research Institute's Richard A. Lerner Wins Prince of Asturias Award for Scientific and Technical Research 3Scripps Research Institute's Richard A. Lerner Wins Prince of Asturias Award for Scientific and Technical Research 4Scripps Research Institute's Richard A. Lerner Wins Prince of Asturias Award for Scientific and Technical Research 5
(Date:3/30/2015)... 30, 2015 Hosted by the ... Cares free, two-day dental clinic in Sacramento provided $2 ... 27-28. , In addition to providing free dental ... barriers to care, CDA Cares educates the public and ... the need for an adequately funded dental safety net, ...
(Date:3/30/2015)... TN (PRWEB) March 30, 2015 Good Shepherd ... need. The Children’s Home in Murfreesboro provides a Christian-based home, ... love of Christ and his special plan for their life. ... of a new day begins as, one-by-one, the children begin ... day begins as the alarm continues to buzz. Sleepily, ...
(Date:3/30/2015)... GoHooper.com announces new website for Grace Pediatrics. ... to infants, children and adolescents and partners with parents ... The owner/provider Mark Hughes, MD, FAAP and a his ... expertise in the extensive range of pediatric care from ... professionals who meet the medical field's highest standards, and ...
(Date:3/30/2015)... (PRWEB) March 30, 2015 Health Fitness Revolution, ... Trainer in the World Samir Becic, has created a new ... 2015 , which recognizes the world’s fittest leaders in terms ... first and only list of its kind to detail the ... ministers. , Among the world leaders profiled on the list ...
(Date:3/30/2015)... (PRWEB) March 30, 2015 Wright & ... liability lawsuits, notes that the number of Syngenta ... litigation underway in U.S. District Court, District of Kansas, ... December 2014. "According to an update released by the ... 16th, at least 493 Syngenta lawsuits are now consolidated ...
Breaking Medicine News(10 mins):Health News:CDA Cares Sacramento Dental Clinic Provides $2 Million in Care 2Health News:Good Shepherd Children’s Home Announces 53rd Year of Providing a Safe-Haven for Children in Need 2Health News:Nashville Web Design Company Announces New Site Launch For Pediatrics Doctor 2Health News:The Top 13 Fittest Heads of State: Why Putin Might Be No. 1 in Health and Fitness 2Health News:Syngenta Corn Lawsuit Claims Continue To Be Filed By Non GMO Corn Farmers Reports Wright & Schulte LLC 2Health News:Syngenta Corn Lawsuit Claims Continue To Be Filed By Non GMO Corn Farmers Reports Wright & Schulte LLC 3
... CIMA of the University of Navarra and the Hospital Donostia ... from high blood pressure are more likely to suffer structural ... the Journal of the American College of Cardiology. ... mechanism is damaging the heart, which in turn makes possible ...
... today sought tougher laws to deal with pre-natal sex detection ... a crime than murder//. ,BJP chief Rajnath Singh also ... order to check their misuse for killing unborn female children., ... foeticide in a country where goddesses are worshipped. Such an ...
... risk for developing the tissue abnormalities, or lesions, that ... infected with multiple genotypes// of the human papillomavirus (HPV) ... the July issue of Cancer Epidemiology, Biomarkers & Prevention. ... tissue at the opening to the womb can harbor ...
... measures the acidity of stomach contents backwashed into the ... pain and throat discomfort// associated with the conventional wired ... ,However, while the new technology appears be better ... diagnosing or managing these patients, said David Mark, M.D., ...
... the Nurses' Health Study has shown that Type 2 diabetes ... common form of glaucoma//, accounting for about 60 to 70% ... issue of the journal Ophthalmology. ,Researchers at the ... School of Public Health and Harvard Medical School observed 76,3128 ...
... report has revealed that U.S. emergency medical care is ... disasters. The need of the hour is to expand ... before and after patients arrive. ,A series ... Institute of Medicine (IOM) have pointed out that overcrowded ...
Cached Medicine News:Health News:Higher Risk for Cervical Cancer Seen Among Women Infected with Multiple HPV Types 2Health News:Higher Risk for Cervical Cancer Seen Among Women Infected with Multiple HPV Types 3Health News:New Reflux Disease Technology More Comfortable, Not More Effective 2Health News:New Reflux Disease Technology More Comfortable, Not More Effective 3Health News:Type 2 Diabetes Increases the Risk of Glaucoma in Women 2Health News:US Emergency Rooms ill prepared for Disasters 2
... table is the most versatile ... was designed for both lower ... with an integrated shoulder attachment. ... purpose operating table for your ...
... Series Outpatient Surgical Table is built to ... other specialty and general purpose surgical tables, ... such as 180-degree top rotation for enhanced ... rails will accommodate a wide variety of ...
... The schaerer axis ... been specially designed for ... maximum C-arm access. The ... possibilities and the offset ...
... body set the high standard for the development ... concept of the plates and the multi-functional joints, ... the patient in an optimum manner. Unrestricted space ... utilised. The desire for safety is a basic ...
Medicine Products: