Navigation Links
Labopharm to Present Poster on Dose Titration of Once-daily,Tramadol at 3rd International Forum on Pain Medicine

- Article Discussing Pharmacokinetics and Dose Proportionality of Company's Once-Daily Tramadol to be Published in Biopharmaceutics Journal -

LAVAL, QC, June 29, 2007 /PRNewswire-FirstCall/ - Labopharm Inc. today announced that it will present a poster discussing the dose titration of its once-daily formulation of tramadol at the 3rd International Forum on Pain Medicine to be held June 28 to July 1, 2007 in Montreal, Canada.

The poster compares two different titration schedules for Labopharm's once-daily formulation of tramadol in three Phase III clinical trials: a six-day titration to a 300 mg dose (clinical trials MDT3-002 and MDT3-003) and a nine-day titration to a 300 mg dose (clinical trial MDT3-005). The comparison showed that percentage of adverse events and discontinuations due to adverse events was similar regardless of the titration schedule.

These results, in addition to the fact that Labopharm's once-daily tramadol formulation achieves steady state plasma levels after two days, suggest that a shorter titration schedule may be adequate for most patients. A previous study showed that most patients achieve pain control using Labopharm's once-daily tramadol at a dose of 200 mg. The data in this poster suggest that, for most patients, after starting with a dose of 100 mg for two days, the therapeutic dose of 200 mg could be achieved after two days without increased risk of side effects. If a patient requires a higher dose (300 mg), the therapeutic dose could be achieved after six days of titration (100 mg for 2 days; 200 mg for 3 days then 300 mg on the 6th day) without increased risk of side effects.

"The results of the comparison of titration periods reviewed in the poster suggest that patients may benefit from rapid titration to optimal analgesia without increased risk of side effects using our product," said James R. Howard-Tripp, President and Chief Executive Officer, Labopharm
'"/>




Page: 1 2 3

Related medicine technology :

1. The Past, Present and Future of HLA Typing
2. Phase 3 Results for Dabigatran Etexilate, an Investigational Oral Anticoagulant, Presented Today at the XXIst Congress of the International Society on Thrombosis and Haemostasis
3. Neose Announces Presentation of Positive Preclinical Data on GlycoPEGylated Factor VIIa at the XXI Congress of the International Society on Thrombosis and Haemostasis
4. Inspiration Biopharmaceuticals Presents Data From Hemophilia Program at International Society On Thrombosis and Haemostasis (ISTH) Annual Meeting
5. Halozyme Therapeutics Enhanze Technology Large Protein Molecule Therapeutic Clinical Trial Results Presented at the 34th Annual Meeting of the Controlled Release Society
6. Generex Biotechnology to Make Presentations At 46th Annual Meeting of the European Society of Pediatric Endocrinology
7. Auxilium Pharmaceuticals to Present at the 2007 CEUT Emerging Growth Opportunities Conference
8. ViaCell to Present at the C.E. Unterberg, Towbin Emerging Growth Opportunities Conference
9. Accelrys to Present to Investors at C.E. Unterberg Emerging Growth Opportunities Conference
10. Metabasis to Present at C.E. Unterberg, Towbin Emerging Growth Conference and Attend Pacific Growth Equities Conference
11. Inspire Announces Webcast of Presentation at C.E. Unterberg, Towbin Emerging Growth Opportunities Conference
Post Your Comments:
(Date:12/19/2014)... Dec. 18, 2014 Research and Markets ... of the "Micro Market Monitor: North American ... offering. http://photos.prnewswire.com/prnh/20130307/600769 ... progressing steadily, which has resulted in fueling the ... The main purpose of these dermatology devices is ...
(Date:12/19/2014)... 2014 Baptist Health Lexington is the first facility ... full Atrial Fibrillation with Electrophysiology Services (EPS) Accreditation status from ... fibrillation is the most common cardiac arrhythmia and has become ... lead to stroke and possible death. More than 5 million ... atrial fibrillation and the numbers are rapidly increasing as the ...
(Date:12/17/2014)... and SAN DIEGO , Dec. ... PHG ; AEX: PHIA) and Volcano Corporation (NASDAQ: ... measurement solutions for cardiovascular applications, today announced that they have ... Philips will commence a tender offer to acquire all of ... per share, or a total equity purchase price of USD ...
Breaking Medicine Technology:Micro Market Monitor: North American Dermatology Diagnostic Devices Market 2Micro Market Monitor: North American Dermatology Diagnostic Devices Market 3Baptist Health Lexington First in the Nation to Receive Atrial Fibrillation with EPS Accreditation 2Baptist Health Lexington First in the Nation to Receive Atrial Fibrillation with EPS Accreditation 3Philips to acquire Volcano to expand global leadership position in image-guided therapy market 2Philips to acquire Volcano to expand global leadership position in image-guided therapy market 3Philips to acquire Volcano to expand global leadership position in image-guided therapy market 4Philips to acquire Volcano to expand global leadership position in image-guided therapy market 5Philips to acquire Volcano to expand global leadership position in image-guided therapy market 6Philips to acquire Volcano to expand global leadership position in image-guided therapy market 7Philips to acquire Volcano to expand global leadership position in image-guided therapy market 8
... Actavis Group, an international generic pharmaceuticals company, today announced ... & Drug Administration to market Valacyclovir Hydrochloride Tablets.   ... gram, the generic equivalent of Valtrex® by GlaxoSmithKline, had ... months ending December 31, 2010, according to IMS Health. ...
... Air Products (NYSE: APD ) announced today ... Imaging, Inc., one of the United States, largest independent ... Illinois. Under the agreement, Air Products will supply its ... currently installed by Genesis for MRI scans at medical ...
Cached Medicine Technology:Actavis Receives Approval of Valacyclovir Hydrochloride Tablets in the U.S. 2Air Products Lands Contract with Genesis for KeepCOLD® Cryogenic Services 2Air Products Lands Contract with Genesis for KeepCOLD® Cryogenic Services 3
(Date:12/19/2014)... HealthDay Reporter THURSDAY, Dec. 18, ... leg for at least 20 seconds you may be at ... on one leg may indicate that small strokes or tiny ... serious strokes is high, the investigators reported online Dec. 18 ... while standing on one leg, as well as problems walking, ...
(Date:12/17/2014)... Mass. (PRWEB) December 17, 2014 ... of Osteopathic Medicine (ACOM), which welcomed its inaugural ... Desktop Infrastructure (VDI) to seamlessly support bring your ... – and teaching – experience. The solution, comprised ... NetScaler , Dell server and storage infrastructure ...
(Date:12/17/2014)... 17, 2014 A group of 127 scientists ... today, in reaction to a recent statement by the center ... training and derogated the efficacy of all brain exercises. , ... the parts of the center’s statement critical of brain exercise ... had also overstated its case, in a document it had ...
(Date:12/17/2014)... 17, 2014 Now in its second ... best of the best in senior living and home ... given to communities and agencies that have received outstanding ... Of the nearly 100,000 providers currently listed on SeniorAdvisor.com, ... the SeniorAdvisor.com Best of 2015 Awards are located all ...
(Date:12/17/2014)... HealthDay Reporter , TUESDAY, Dec. 16, 2014 (HealthDay ... phenomenon is when an illness that originated in animals jumps ... -- is not uncommon and keeps researchers on their toes ... make inroads into the human population. A new report ... in this case were guinea pigs. More specifically, they were ...
Breaking Medicine News(10 mins):Health News:Can You Balance on One Leg? You May Have Lower Stroke Risk 2Health News:Alabama College of Osteopathic Medicine Deploys Desktop Virtualization Solution from Citrix, Dell and Unidesk 2Health News:Alabama College of Osteopathic Medicine Deploys Desktop Virtualization Solution from Citrix, Dell and Unidesk 3Health News:Scientists to Stanford: Research Shows Brain Exercises Can Work 2Health News:Scientists to Stanford: Research Shows Brain Exercises Can Work 3Health News:Scientists to Stanford: Research Shows Brain Exercises Can Work 4Health News:The Inn at Willow Falls - Crest Hill, IL Wins 2015 Best of Assisted Living Award from SeniorAdvisor.com 2Health News:The Inn at Willow Falls - Crest Hill, IL Wins 2015 Best of Assisted Living Award from SeniorAdvisor.com 3Health News:Guinea Pigs Can Be Source of Serious Strep Infection 2Health News:Guinea Pigs Can Be Source of Serious Strep Infection 3
... diseases. The correlation states that intake of beta-carotene //shows ... ,The association between the risk and beta-carotene intake ... to the authors of the study. ,The finding ... raises the risk of cancer in smokers, or carotene ...
... revealed that mental processes can change across the ... has been implicated in the representation of emotional ... association learning, motivation, and socio-emotional control. ... early edition of the Proceedings of the National ...
... of childhood obesity, The Alliance for a Healthier Generation, ... and the American Heart Association, has announced that it ... Just Play pro-social campaign. ,The three organisations are ... campaign, encouraging young people to inculcate better and healthier ...
... oldest and largest museum in India situated in National ... collection of 100,000 mosquitoes, plague-hit rats, guinea worms and ... the oldest and largest such collection in South and ... used in fighting killer disease outbreaks. Scientists and researchers ...
... regarded as nutritionally good compounds. Lot of research is ... found in herbs, fruits, and vegetables, slowed the growth ... study. ,Previous studies already found flavonoids (found in ... a number of cancers. ,The current study was ...
... major development in Germany since the 2003,ruling by the ... introduction of crossover transplantation, German surgeons have performed a cross ... a court ruling making the procedure legal in certain circumstances. ... one couple donates his or her kidney to the ill ...
Cached Medicine News:Health News:MRI Shows Emotional Changes During Menstrual Cycle 2Health News:A New Initiative To Fight Childhood Obesity 2Health News:India Has The Oldest And Largest Collection Of Preserved Mosquitoes – Mosquito Museu 2Health News:Prostate tumour growth suppressed by flavonoids 2Health News:First Crossover Kidney Transplantation In Germany 2Health News:First Crossover Kidney Transplantation In Germany 3
... The new DeVilbiss PulmoAide Compact Compressor provides ... small size allows for therapy at home or ... a 5-year warranty, and the same reliable operation ... ,The PulmoAide Compact Compressor is the perfect ...
... an important part of managing the disease ... products mean delivering the aerosolized medication to ... minimizing medication waste. Aerosol delivery with the ... Nebulizers, including the new NebuTech® HDN®, helps ...
The 16 liter Laparoscopy Insufflator combines high safety and precise pressure control with simple operation....
The ACMI TurboFlow 18 L and 10 L Insufflators provide rapid distention for all laparoscopic procedures. Eleven built-in safety features make insufflation reliable and dependable....
Medicine Products: