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Hypertension Vaccine CYT006-AngQb Achieves Strong Blood Pressure,Reduction During Important Early Morning Period When Most Adverse,Cardiovascular Events Occur

d responds to a certain interaction partner such as hormones, immune mediators or other
Renin: enzyme that catalyzes the formation of angiotensin I (Ang I) from its precursor angiotensinogen and thus initiates the reninangiotensin
system cascade.
Run-in period: time window during which blood pressure monitoring devices are placed at the participants by specialized staff and first
measurements begin. During this time window blood pressure values can be influenced by the general handling and the contact with the
doctor (so called “white coat effect”).
SBP: systolic blood pressure.
Small molecule drugs: low molecular weight chemical compounds. Many pharmaceutical drugs are small molecules.
Stroke: a sudden interruption in the blood supply of the brain. Most strokes are caused by an abrupt blockage of arteries leading to the
brain; others are caused by bleeding into brain tissue when a blood vessel bursts (see also intracerebral hemorrhage).
Systolic blood pressure: the highest pressure within the arterial blood stream occurring during each heart beat. “Systolic” refers to the
contraction of the heart muscle.
Therapeutic vaccine: a preparation of disease-related molecules (antigens) of foreign or self origin that is capable of activating the
immune system against such antigens with the goal to modulate disease processes.
This foregoing press release may contain forward-looking statements that include words or phrases such as “potentially”, “may”, “would”, “suggest”,
“should”, “might”, “designed”, “intend” or other similar expressions. These forward-looking statements are subject to a variety of significant
uncertainties, including scientific, business, economic and financial factors, and therefore actual results may differ significantly fro

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