Navigation Links
Hypertension Vaccine CYT006-AngQb Achieves Strong Blood Pressure,Reduction During Important Early Morning Period When Most Adverse,Cardiovascular Events Occur

- Blood pressure reduction achieved at 8 am versus placebo: - 25 / - 13 mm Hg (systolic / diastolic, p<0.0001 / p=0.0035)
- Blood pressure reduction dependent on vaccine dose and induced antiangiotensin II antibody levels
- Detailed results presented today at the Seventeenth European Meeting on Hypertension in Milan, Italy

SCHLIEREN (Zurich), Switzerland and MILAN, Italy, June 17, 2007 - Cytos Biotechnology AG (SWX:CYTN) presented today new clinical data on its hypertension vaccine CYT006-AngQb at the Seventeenth European Meeting on Hypertension in Milan, Italy. The vaccine candidate was tested in a placebocontrolled, double-blind phase IIa clinical trial in 72 patients with mild to moderate hypertension.

On January 26, 2007, Cytos Biotechnology reported top-line data from this study, which showed that the 300 ?g dose of the vaccine was safe, very well tolerated and efficacious in lowering day-time ambulatory blood pressure. The new data presented today show a particularly strong efficacy of the vaccine in early morning hours, a critical time period when serious cardiovascular events frequently occur. The graph below shows the mean ambulatory blood pressure during the 24-hour measurement period 14 weeks after the first injection of the vaccine or of placebo. The early morning rise of blood pressure starting at 5 am was significantly suppressed by the vaccine, leading at 8 am to a change from baseline of the blood pressure of - 25 / - 13 mm Hg compared to placebo (SBP / DBP, p<0.0001 / p=0.0035).


*SEE ATTACHMENT FOR FIGURE*

The strong suppression of the early morning rise of blood pressure was associated with an exceptionally low increase in plasma renin concentration (PRC) from a mean renin concentration of 5.1 pg/ml at baseline to 6.3 pg/ml at week 14 (p=0.02). Inhibition of the renin-angiotensin system by small molecule drugs is known to induce a reactive rise of the plasma renin concentrati
'"/>




Page: 1 2 3 4 5 6 7 8 9

Related medicine technology :

1. Speedel Reports Successful SPP635 Phase IIa Trial in Hypertension
2. Prexige Study Shows Significantly Less Impact on Blood Pressure Than Ibuprofen in Osteoarthritis Patients with Controlled Hypertension
3. Lumiracoxib Study Showed Significantly Less Impact on Blood Pressure Than Ibuprofen in Osteoarthritis Patients with Controlled Hypertension
4. Amlodipine and Olmesartan Study Results Released;Late Breaker Presented at American Society of Hypertension Twenty-Second Annual Scientific Meeting (ASH 2007)
5. Gilead Announces Presentation of Long-Term Data for Ambrisentan, a Potential Treatment for Patients With Pulmonary Arterial Hypertension
6. Hypertension Education Foundation Survey Results Announced At American Society For Hypertension Annual Meeting Suggests Improved Control Of High Blood Pressure, But Misconceptions Still Exist
7. New Data Highlights Potential of SPP100 (Tekturna) as Gold Standard Therapy in Treatment of Hypertension
8. Amlodipine and Olmesartan Study Results Released; Late Breaker Presented at American Society of Hypertension Twenty-Second Annual Scientific Meeting (ASH 2007)
9. King Pharmaceuticals Announces Plan to Present Results from Phase III Clinical Trial Evaluating ALTACE as Monotherapy and in Combination with Hydrochlorothiazide at the American Society of Hypertension Annual Meeting
10. Landmark Findings From ECLIPSE Program Show Improved Control of Perioperative Hypertension Reduces Risk of Death In Cardiac Surgery
11. BioSante Pharmaceuticals Announces New Findings for Potential Bird Flu Vaccine
Post Your Comments:
(Date:4/24/2015)... EAST HANOVER, N.J. , April 24, 2015  Novartis ... diversity for the second year in a row on the ... the results of its 2015 Top 50 Companies for Diversity ... New York, NY . NPC also ranked second on ... on the Top 10 Companies for Employee Resource Groups list. ...
(Date:4/24/2015)... Hi-Tech Pharmaceuticals refutes the results from ... of reliable scientific principles and methods and therefore ... of adulteration. The FDA is resting its very, ... misguided hope, that Methylphenylethylamine is not found in ... multiple other studies and cannot be relied on ...
(Date:4/24/2015)... 24, 2015 /CNW/ - T-Bird Pharma Inc. (TSXV:TPI) ("T-Bird" ... premium quality medical marijuana products and a licensed producer ... Purposes Regulations ( Canada ) ("MMPR"), is ... its shareholders, has closed the transaction announced on March ... acquired (the "Escrow Transfer") a total of 20,156,790 common ...
Breaking Medicine Technology:Novartis Pharmaceuticals Corporation is first company to receive number one ranking two years in a row on DiversityInc Top 50 Companies for Diversity list 2Novartis Pharmaceuticals Corporation is first company to receive number one ranking two years in a row on DiversityInc Top 50 Companies for Diversity list 3Novartis Pharmaceuticals Corporation is first company to receive number one ranking two years in a row on DiversityInc Top 50 Companies for Diversity list 4Hi-Tech Responds to "Bullying Tactics" Issued by FDA on Acacia Rigidula 2Hi-Tech Responds to "Bullying Tactics" Issued by FDA on Acacia Rigidula 3Hi-Tech Responds to "Bullying Tactics" Issued by FDA on Acacia Rigidula 4Hi-Tech Responds to "Bullying Tactics" Issued by FDA on Acacia Rigidula 5Hi-Tech Responds to "Bullying Tactics" Issued by FDA on Acacia Rigidula 6T-Bird Pharma Inc. Announces Closing of Transaction with Medna Biosciences 2T-Bird Pharma Inc. Announces Closing of Transaction with Medna Biosciences 3
... YORK, Oct. 5 Reportlinker.com announces that a ... catalogue: Nanobiotechnologies- applications, markets and ... SummaryNanotechnology is the creation and ... control of matter on the nanometer-length scale (a ...
... The Thompson Group of Companies announced today that it ... Hamilton Sundstrand Corporation business. AIT will be organized as ... of the purchase were not disclosed. AIT ... of process analytical instruments including Analect FTIR, PIONIR Near-Infrared, ...
Cached Medicine Technology:Reportlinker Adds Nanobiotechnologies - Applications, Markets and Companies 2Reportlinker Adds Nanobiotechnologies - Applications, Markets and Companies 3Reportlinker Adds Nanobiotechnologies - Applications, Markets and Companies 4Reportlinker Adds Nanobiotechnologies - Applications, Markets and Companies 5Reportlinker Adds Nanobiotechnologies - Applications, Markets and Companies 6Reportlinker Adds Nanobiotechnologies - Applications, Markets and Companies 7Reportlinker Adds Nanobiotechnologies - Applications, Markets and Companies 8Reportlinker Adds Nanobiotechnologies - Applications, Markets and Companies 9Reportlinker Adds Nanobiotechnologies - Applications, Markets and Companies 10Reportlinker Adds Nanobiotechnologies - Applications, Markets and Companies 11Reportlinker Adds Nanobiotechnologies - Applications, Markets and Companies 12Reportlinker Adds Nanobiotechnologies - Applications, Markets and Companies 13Reportlinker Adds Nanobiotechnologies - Applications, Markets and Companies 14Reportlinker Adds Nanobiotechnologies - Applications, Markets and Companies 15Reportlinker Adds Nanobiotechnologies - Applications, Markets and Companies 16Reportlinker Adds Nanobiotechnologies - Applications, Markets and Companies 17Reportlinker Adds Nanobiotechnologies - Applications, Markets and Companies 18Reportlinker Adds Nanobiotechnologies - Applications, Markets and Companies 19Reportlinker Adds Nanobiotechnologies - Applications, Markets and Companies 20Reportlinker Adds Nanobiotechnologies - Applications, Markets and Companies 21Thompson Group Acquires Hamilton Sundstrand's Applied Instrument Technologies 2
(Date:4/24/2015)... Lowcostcarinsuranceprice.com has released a new blog ... insurance for senior citizens . , Senior citizens ... not mean that they cannot find affordable coverage. By ... find the right coverage for their cars at the ... http://lowcostcarinsuranceprice.com/ provides free leads from various agencies ...
(Date:4/24/2015)... BC (PRWEB) April 24, 2015 Olive ... Yuzpe, Olive Fertility co-founder and co-director, has been honoured ... Preservation at the Evening of Hope Gala. , ... recognize Dr. Albert Yuzpe, who has been at the ... 43 years,” says Jessica Séguin, Executive Director of Fertile ...
(Date:4/24/2015)... 2015 National Access Cannabis ... access to medical cannabis, is taking a leadership role ... advising patients. , NAC is the first to back ... $250,000 grant, NAC will be providing 300 healthcare professionals ... is to help Canadians gain safe and responsible access ...
(Date:4/24/2015)... Telematics Berlin is the foremost Automotive Data event ... suppliers, content providers, associations and government bodies. From industry ... see them converge in Berlin. This year’s start-up competition ... companies currently at the forefront of Europe’s Silicon Valley ... centric products, ParkTAG are one of the first social ...
(Date:4/24/2015)... 2015 PURE Solutions, a leader in ... Network (The Network), a highly respected education, advocacy and ... tips and information for a special allergy ... , The goal for both organizations is to “make ... of people with asthma and allergies and by finding ...
Breaking Medicine News(10 mins):Health News:Low Cost Auto Insurance Quotes for Senior Citizens 2Health News:Olive Fertility Centre Co-founder, Dr Al Yuzpe, Recognized as a Pioneer in Fertility Preservation 2Health News:National Access Cannabis Gives 300 Canadian Healthcare Professionals Access to Medical Cannabis Certificate Program 2Health News:Telematics Berlin 2015’s inaugural European Automotive Start-Up Competition 2Health News:Telematics Berlin 2015’s inaugural European Automotive Start-Up Competition 3Health News:PURE Solutions Partners with Allergy and Asthma Network to Provide Allergy Travel Tips 2
... ... Higher Value Products, PHOENIX, Feb. 4 NutraCea ... nutrient research and,technology, announced today that it has executed a definitive ... America,located in Brazil. This transaction is expected to close prior to ...
... SAP Public Services, Inc.,a subsidiary of SAP AG ... as vice,president of its U.S. healthcare practice. The ... and,government-driven initiatives to improve the quality and delivery ... responsible for growing,SAP,s business in the U.S. healthcare ...
... Stage of Growth and Development, RESTON, Va., ... Mirixa,Corporation announced today that Donald W. Hackett, chief ... the company, effective,immediately., Bruce Roberts, RPh, executive ... Association (NCPA) and chairman of Mirixa,s board of,directors, ...
... Inhaled Corticosteroid approved for ... Young as Age 4, KENILWORTH, N.J., Feb. 4 ... Food and Drug,Administration (FDA) has approved ASMANEX (R) TWISTHALER (R) ... as a preventive therapy in patients 4 to 11 years ...
... 4 (OTC Pinksheets: HRAL) -,HearAtLast Holdings, Inc. ... another,license from Wal-Mart Canada (NYSE: WMT ) ... co-located within Wal-Mart Store #5778 located at 135,First ... is scheduled,for Tuesday, February the 5th, 2008. The ...
... Increase Awareness, Education about Bone Disease, ... about the bone-weakening disease osteoporosis, the Pennsylvania,Commission ... Dairy Association,and Pennsylvania Dairy Promotion Program to ... Bedford, Cameron, Clinton, Juniata,Perry, Sullivan, and Tioga ...
Cached Medicine News:Health News:NutraCea to Purchase Largest Rice Bran Oil Processing Facility in South America 2Health News:NutraCea to Purchase Largest Rice Bran Oil Processing Facility in South America 3Health News:NutraCea to Purchase Largest Rice Bran Oil Processing Facility in South America 4Health News:SAP Names David Corbett as Vice President of U.S. Healthcare Practice 2Health News:SAP Names David Corbett as Vice President of U.S. Healthcare Practice 3Health News:SAP Names David Corbett as Vice President of U.S. Healthcare Practice 4Health News:SAP Names David Corbett as Vice President of U.S. Healthcare Practice 5Health News:Mirixa Corporation Announces Leadership Change 2Health News:FDA Approves ASMANEX (R) TWISTHALER(R) (Mometasone Furoate Inhalation Powder) for the Once Daily Maintenance Treatment of Asthma in Children Ages 4-11 2Health News:FDA Approves ASMANEX (R) TWISTHALER(R) (Mometasone Furoate Inhalation Powder) for the Once Daily Maintenance Treatment of Asthma in Children Ages 4-11 3Health News:FDA Approves ASMANEX (R) TWISTHALER(R) (Mometasone Furoate Inhalation Powder) for the Once Daily Maintenance Treatment of Asthma in Children Ages 4-11 4Health News:FDA Approves ASMANEX (R) TWISTHALER(R) (Mometasone Furoate Inhalation Powder) for the Once Daily Maintenance Treatment of Asthma in Children Ages 4-11 5Health News:FDA Approves ASMANEX (R) TWISTHALER(R) (Mometasone Furoate Inhalation Powder) for the Once Daily Maintenance Treatment of Asthma in Children Ages 4-11 6Health News:HearAtLast Expands Chain to 18 Locations Opening New Clinic in Aurora, Ontario Wal-Mart Store # 5778 2Health News:HearAtLast Expands Chain to 18 Locations Opening New Clinic in Aurora, Ontario Wal-Mart Store # 5778 3Health News:HearAtLast Expands Chain to 18 Locations Opening New Clinic in Aurora, Ontario Wal-Mart Store # 5778 4Health News:PA Commission for Women Announces 'Shocking Pink' Osteoporosis Campaign in Rural PA 2
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: