Navigation Links
Zafgen Announces Initial Results from Phase 2a Study of Beloranib in Patients with Prader-Willi Syndrome
Date:1/15/2014

ed by an additional four weeks of open label treatment, the results of which are not yet available.  The trial enrolled 17 patients with genetically confirmed PWS, including 11 women and 6 men, with a mean age of 33.9 years, and mean body mass index (BMI) of 31.4 kg/m2.  Beloranib appeared to be safe and very well-tolerated.  All 17 patients completed the randomized treatment part of the trial and all opted to continue into and completed the four-week open label extension.

About Prader-Willi Syndrome
Prader-Willi syndrome (PWS), the most common known genetic cause of life-threatening obesity, causes constant hunger that drives PWS patients to gain more weight on fewer calories than the average person.  As a result, many of those affected become morbidly obese before the age of five.  There is currently no cure for this disease.  Although the cause is complex, it results from a deletion or loss of function of a cluster of genes on the 15th chromosome.  PWS typically causes low muscle mass and function, short stature, incomplete sexual development, and a chronic feeling of hunger that, coupled with a metabolism that utilizes drastically fewer calories than normal, can lead to excessive eating and life-threatening obesity.  PWS occurs in males and females equally and in all races, with the same incidence around the world.  Prevalence estimates have ranged from 1:8,000 to 1:50,000 with the most likely figure being approximately 1:40,000.  To the best of our knowledge, prevalence is about 5,000-7,000 people in the United States needing treatment.  You can learn more through the Prader-Willi Syndrome Association website at www.pwsausa.org.

About Beloranib
Beloranib is the first compound in its class that works by targeting a key enzyme called MetAP2 that controls the production and utilization of fatty acids.  Inh
'/>"/>

SOURCE Zafgen, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Zafgen Announces Initiation of Phase 2a Clinical Development with Beloranib in Obesity
2. Zafgen Secures $21 Million in Series D Financing
3. Zafgen Announces New Weight Loss and Safety Data from Phase 2 Study of Beloranib in Obesity at Obesity Week 2013
4. Zafgen Secures $45 Million in Series E Financing
5. Zafgen Appoints Chief Commercial Officer and New Member of Board of Directors
6. Precision Optics Corporation Announces $1 Million Order for Microprecision™ Based Endoscopes
7. Young Innovations, Inc. Announces Record Sales and EPS for the Quarter Ended March 31, 2012
8. JDRF Announces Research Collaboration with Dexcom, Inc. to Develop "Smart Transmitter" Technology to Accelerate Artificial Pancreas Studies
9. Misonix Announces New Distribution Agreement For Panama
10. University of Maryland BioPark Announces MedImmunes Dr. Bahija Jallal as Newest Member of Board of Directors for UM Health Sciences Research Park
11. Novelos Therapeutics Announces Successful Completion of First Cohort In Lung Cancer Trial With I-124-CLR1404 (LIGHT) Cancer-Targeted PET Imaging Agent at UW Carbone Cancer Center
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/22/2014)... Aug. 22, 2014  Dr. Mark Rasak , ... Diamond Lifetime Achievement Award in the field of Medicine ... Cardiovascular Clinical Associates. Dr. Rasak has over ... major aspects of the business; overseeing the daily operations; ... coronary intervention. In addition, he is an honored Fellow ...
(Date:8/22/2014)... , Aug. 22, 2014   Zacks Equity Research ... Bull of the Day and Panera (Nasdaq: PNRA - Free ... Equity Research provides analysis on Amicus Therapeutics (Nasdaq: FOLD - ... and Shire (Nasdaq: SHPG - Free Report ). ... Bull of the Day : The biotech ...
(Date:8/22/2014)... , Aug. 22, 2014  Mark Riccio, ... (CT) imaging facility, is using the online crowd-funding ... even 5D imaging to researchers and would-be superheros ... asks "What would YOU do if you had ... to researchers and explorers everywhere, from elementary through ...
Breaking Medicine Technology:Dr. Mark Rasak, MD is recognized by Continental Who's Who with the Diamond Lifetime Achievement Award 2Epizyme, Panera, Amicus Therapeutics, Sanofi and Shire highlighted as Zacks Bull and Bear of the Day 2Epizyme, Panera, Amicus Therapeutics, Sanofi and Shire highlighted as Zacks Bull and Bear of the Day 3Epizyme, Panera, Amicus Therapeutics, Sanofi and Shire highlighted as Zacks Bull and Bear of the Day 4Epizyme, Panera, Amicus Therapeutics, Sanofi and Shire highlighted as Zacks Bull and Bear of the Day 5Epizyme, Panera, Amicus Therapeutics, Sanofi and Shire highlighted as Zacks Bull and Bear of the Day 6Cornell's X-ray Imaging Lab Director Uses Kickstarter Campaign to "Democratize" Advanced 3D Imaging 2
... Reportlinker.com announces that a new market research ... Process Analytical Technologies for Pharmaceuticals: Global Markets ... The global market for process analytical technology (PAT) ... 2010. This market is expected to increase by ...
... -- China Medicine Corporation (OTC Bulletin Board: ... distributor of Western pharmaceuticals, traditional Chinese medicines ("TCM"), and ... today announced that it has filed with the United ... on Form 8-K to disclose that its previously issued ...
Cached Medicine Technology:Reportlinker Adds Process Analytical Technologies for Pharmaceuticals: Global Markets 2Reportlinker Adds Process Analytical Technologies for Pharmaceuticals: Global Markets 3Reportlinker Adds Process Analytical Technologies for Pharmaceuticals: Global Markets 4Reportlinker Adds Process Analytical Technologies for Pharmaceuticals: Global Markets 5Reportlinker Adds Process Analytical Technologies for Pharmaceuticals: Global Markets 6Reportlinker Adds Process Analytical Technologies for Pharmaceuticals: Global Markets 7Reportlinker Adds Process Analytical Technologies for Pharmaceuticals: Global Markets 8Reportlinker Adds Process Analytical Technologies for Pharmaceuticals: Global Markets 9Reportlinker Adds Process Analytical Technologies for Pharmaceuticals: Global Markets 10Reportlinker Adds Process Analytical Technologies for Pharmaceuticals: Global Markets 11Reportlinker Adds Process Analytical Technologies for Pharmaceuticals: Global Markets 12Reportlinker Adds Process Analytical Technologies for Pharmaceuticals: Global Markets 13Reportlinker Adds Process Analytical Technologies for Pharmaceuticals: Global Markets 14Reportlinker Adds Process Analytical Technologies for Pharmaceuticals: Global Markets 15China Medicine Corporation Files Extension for Fiscal 2010 Form 10-K Filing 2China Medicine Corporation Files Extension for Fiscal 2010 Form 10-K Filing 3
(Date:8/23/2014)... York, New York (PRWEB) August 23, 2014 ... http://www.consumerinjurylawyers.com/wright-conserve-hip-replacement.html ) filed on behalf of individuals ... the Conserve hip replacement line continue to move ... of Georgia, Bernstein Liebhard LLP reports. According to ... established a bellwether trial program that would allow ...
(Date:8/23/2014)... August 23, 2014 Professional kitchen employees, ... study aid in preparing for Food Safety Certification exams ... by Dynamic Path. , Dynamic Path announced the ... includes more than 200 review questions for culinary industry ... designed to cover requirements of the ServSafe® Food Safety ...
(Date:8/23/2014)... August 23, 2014 Teen drug and ... It’s no different in Wilmington, NC. Substance abuse can ... falling victim to drug and alcohol dependency in higher ... looking to overcome substance abuse, but don’t know where ... treatment facility can be a challenge because most treatment ...
(Date:8/22/2014)... 23, 2014 2014 Deep Research ... professional and in-depth research report on the Glucose ... information, including Glucose Meter definition, classification, application, and ... This research covers the international market analysis, including ... covering macroeconomic environment & economic situation analysis. The ...
(Date:8/22/2014)... (PRWEB) August 23, 2014 Top ... many famous web hosting companies and highly recommended ... customers. , The manager of Top 10 Best ... a good dedicated server hosting supplier. Actually, these ... uptime, server speed and customer support. People can ...
Breaking Medicine News(10 mins):Health News:Wright Conserve Hip Lawsuits Move Forward, as Federal Court Issues Order Pertaining to Bellwether Trials, Bernstein Liebhard LLP Reports 2Health News:Wright Conserve Hip Lawsuits Move Forward, as Federal Court Issues Order Pertaining to Bellwether Trials, Bernstein Liebhard LLP Reports 3Health News:Wright Conserve Hip Lawsuits Move Forward, as Federal Court Issues Order Pertaining to Bellwether Trials, Bernstein Liebhard LLP Reports 4Health News:Food Handler Safety Certification Made Easy with Dynamic Path 2Health News:Troubled Teens Wilmington Helpline Guides Adolescents to the Path of Recovery 2Health News:Glucose Meter Industry Global (Europe, Asia, NA, ROW) Analysis Now Available at ReportsnReports.com 2Health News:Glucose Meter Industry Global (Europe, Asia, NA, ROW) Analysis Now Available at ReportsnReports.com 3Health News:FatCow Reviews Released by Top10BestSEOHosting.com 2
... unlikely to receive consistent treatment, researchers say. ... the hospital before babies are even born. The ... Hospital Psychiatry , tracked 20 health care providers in ... in addressing perinatal depression. "There are a ...
... depression during pregnancy or shortly after giving birth. Although the ... known about the causes or early-warning signs of pregnancy-related depression. ... Journal of Women,s Health , researchers at the University ... new clues to help doctors identify at-risk patients and refer ...
... An experimental vaccine developed by researchers at Cedars-Sinai ... in highly aggressive brain tumors and improves length of ... that was presented in a poster session at the ... Oncology. Patients with newly diagnosed glioblastoma multiforme, ...
... People often talk about "boosting" their immunity to prevent ... foods claim to stave off colds by augmenting the ... shows this strategy might actually be flawed. The ... who often experience life-threatening flare-ups due to infections with ...
... Spring Harbor Laboratory (CSHL) have obtained a precise molecular ... in a subtype of the NMDA (N-methyl-D-aspartate) receptor, which ... newly discovered binding site -- a docking port within ... potential target for drugs that can modulate NMDA receptors, ...
... treatment gap is leaving millions of people at high ... in ,Osteoporosis: Burden, health care provision and opportunities in ... Osteoporosis Foundation (IOF) in collaboration with the European Federation ... only a minority of high risk patients are receiving ...
Cached Medicine News:Health News:Depressed, pregnant women receive inconsistent treatment, have longer hospital stays 2Health News:Pregnancy-related depression linked to eating disorders and abuse histories 2Health News:Latest data from Cedars-Sinai vaccine study supports immune targeting of brain tumors 2Health News:Latest data from Cedars-Sinai vaccine study supports immune targeting of brain tumors 3Health News:Heightened immunity to colds makes asthma flare-ups worse, U-M research shows 2Health News:CSHL structural biologists reveal novel drug binding site in NMDA receptor subunit 2Health News:Treatment gap leaves many older adults at unnecessary risk of fracture 2Health News:Treatment gap leaves many older adults at unnecessary risk of fracture 3
... utilize Linvatecs exclusive Shockflex prism system to ... Using the latest technology, our 3CCD Camera ... and brightness. The Camera Heads are available ... configured with a number of optical couplers ...
... an integrated coupler can be steam sterilized using ... it is cool to the touch and ready ... Smarthead technology allowing each head to store procedure ... head has been used is displayed on the ...
... invasive surgery is founded on superior medical ... of 3-Chip cameras, 1-Chip cameras, Light sources, ... your demanding needs., ,Superior resolution and ... our 3-Chip cameras, and are the benchmark ...
... high-resolution 1-Chip Camera System provides easy-to-use features, ... small scope. The camera head construction is ... ,Complete 1-Chip Camera System for Microscopic Application, ... Camera Control Unit (CCU) with power cord ...
Medicine Products: