Navigation Links
Video: Sirion Therapeutics Launches Durezol for Postoperative Ocular Inflammation and Pain
Date:10/6/2008

dies that evaluated Durezol for the management of postoperative inflammation in which treatment was initiated one day prior to surgery. The multicenter, randomized, double-masked, placebo-controlled, parallel-group trials were conducted in 245 patients undergoing unilateral ocular surgery. In the first study of 124 patients, Durezol or placebo was dosed 4 times daily (QID), while in the second study, 121 patients received Durezol or placebo twice daily (BID).

"The Phase 3b studies represent an approach to therapy that is most similar to the current standard of care, meaning most physicians treat inflammation prophylactically rather than waiting for it to occur," explained Steven Silverstein, M.D. of Silverstein Eye Centers. Dr. Silverstein was a principal investigator in the QID study and also serves as a clinical assistant professor of ophthalmology at the University of Missouri-Kansas City School of Medicine and the University of Health Sciences. "Overall, the results from these studies show that by any definition utilized, Durezol administered both BID and QID was more effective than placebo in treating postoperative ocular inflammation and relieving ocular pain/discomfort as early as Day 3/4."

A significantly greater percentage of patients receiving Durezol QID or BID achieved a clinical response (defined as less than or equal to 5 anterior chamber cells and no flare) by Day 14: 81.3% of the Durezol treated patients in the QID group had a clinical response versus 25.0% of the placebo QID group (P < 0.0001); 74.7% of the Durezol BID patients had a clinical response versus 42.5% of patients in the placebo BID group (P < 0.001). Both Durezol groups maintained superiority over the placebo groups through Day 28, demonstrating that efficacy was definitive and did not decrease or reverse over time.

Ocular pain/discomfort was measured using the Visual Analogue Scale (VAS) score of 0-100 with 0 equal to no pain and 100 equal to maximal pain. The perc
'/>"/>

SOURCE Sirion Therapeutics, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Video: New Research Discovers Independent Brain Networks Control Human Walking
2. Video: Landmark Study in The Lancet: Patients Treated With Betaseron(R) After First MS Attack Experienced Significant Delay in MS Progression
3. Video: The Arizona Heart Institute Announces the Largest Worldwide Experience with Endoluminal Grafting to Treat Thoracic Aortic Aneurysms and Related Pathologies
4. Video: Actress and New Mom Keri Russell Joins PKIDs to Launch Silence the Sounds of Pertussis Campaign
5. Video: Quest Diagnostics Health Trends(TM) Report Shows Significant Gap in Care for Patients With Chronic Kidney Disease
6. Video: New Results From One of the Worlds Largest Breast Cancer Trials Herald Hope for Thousands of Women
7. VIDEO: Femara(R) helps protect against return of breast cancer even when treatment starts several years after completing tamoxifen therapy
8. Video: The Journal, Human Genetics, Publishes Results Supporting Interleukin Genetics Heart Health Test
9. Video: Major Independent Trial Demonstrates Significant Anticancer Benefit of Zometa(R) in Women With Early-Stage Breast Cancer
10. Video: Clinical Study Shows Liraglutide Reduced Blood Sugar, Weight, and Blood Pressure in Patients with Type 2 Diabetes
11. Video: Sanford Healths Journey to Cure Type 1 Diabetes Receives Major Boost
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2015)... , July 31, 2015 Today, the ... (NABP ® ) issued a report urging greater ... action is taken against websites illegally selling medications ... Drug Outlet Identification Program Progress Report for State ... thousands of websites illegally distribute medications and ...
(Date:7/31/2015)... BOSTON , July 31, 2015  Boston ... children benefiting from 3D printing of their anatomy ... had life-threatening cerebrovascular malformations (abnormalities in the brain,s ... Reporting online today in the Journal ... use of 3D printing and synthetic resins to ...
(Date:7/31/2015)... 2015 Quietly, sedately, Morocco,s pharmaceutical ... domestic pharmaceutical industry is strong, with a well-developed base ... international standards. One place where the quality ... Africa: Morocco has quietly become the second largest African ... . Indeed, Moroccan pharma companies have been making ...
Breaking Medicine Technology:NABP Stresses Need for Accountability in Enforcing Internet Policies to Protect the Public From Illegal Online Drug Sellers 2NABP Stresses Need for Accountability in Enforcing Internet Policies to Protect the Public From Illegal Online Drug Sellers 33D Printing Helps Doctors Rehearse Complex Brain Procedures 23D Printing Helps Doctors Rehearse Complex Brain Procedures 33D Printing Helps Doctors Rehearse Complex Brain Procedures 4PharmaBoardroom Releases New Morocco Pharmaceuticals Report 2PharmaBoardroom Releases New Morocco Pharmaceuticals Report 3
... BEND, Ore. and NOTTINGHAM, England, Nov. 10, 2010 ... leading independent drug-formulation development and manufacturing company, and ... ("Quotient," www.quotientbioresearch.com ), a leading developer of ... collaboration that can speed the advance of compounds ...
... Group (MRG), the global authority on medical technology market ... multiple geographies, including the US, Canada, Europe, Japan, Brazil, ... specific devices such as internal fixation devices, including plates ... as external fixation devices. They also provide a detailed ...
Cached Medicine Technology:Quotient Clinical and Bend Research Announce Collaboration to Accelerate Advancement of New Medicines 2Quotient Clinical and Bend Research Announce Collaboration to Accelerate Advancement of New Medicines 3New Trauma Market Research Data Covering Multiple Geographies Released by Millennium Research Group 2
(Date:7/31/2015)... ... August 01, 2015 , ... The Honor Society of Nursing, Sigma Theta Tau ... of Nursing (GAPFON) 20-21 July 2015 in San Juan, Puerto Rico. Key nurse leaders ... Dr. Silvia Cassiani, Advisor, Nursing and Allied Health Personnel Development, Unit of Human Resources ...
(Date:7/31/2015)... ... ... Ticket Down is a reliable source for authentic tickets for the 2015 ... festival will end on Sunday, August 2nd. , Music fans have traveled ... unique and unbelievably popular festival attracts the best in entertainment from around the world. ...
(Date:7/31/2015)... ... 2015 , ... Recently touted by Becker’s Healthcare as one ... , Jvion continues to disrupt the predictive analytic and big data market using ... population level illness to drive prevention and better health outcomes. Most recently, Jvion ...
(Date:7/31/2015)... Tenn. (PRWEB) , ... July 31, 2015 , ... The ... Robert Church Park in Downtown Memphis on October 3, 2015. The Ride to Fight ... focused on cancer research between Methodist Healthcare, The West Clinic and The University of ...
(Date:7/31/2015)... (PRWEB) , ... July 31, 2015 , ... There’s no ... possible, even when it comes time to cook the next meal, making July the ... July by practicing best grilling tips and recipes. , Make the next cookout different ...
Breaking Medicine News(10 mins):Health News:Key Latin American Nurse Leaders Identify Regional Issues During Global Advisory Panel on the Future of Nursing Meeting 2Health News:Key Latin American Nurse Leaders Identify Regional Issues During Global Advisory Panel on the Future of Nursing Meeting 3Health News:Key Latin American Nurse Leaders Identify Regional Issues During Global Advisory Panel on the Future of Nursing Meeting 4Health News:Cheap 2015 Lollapalooza Tickets: Ticket Down Slashes Ticket Prices on Lollapalooza Tickets at Grant Park in Chicago for Saturday, August 1st and Sunday, August 2nd 2Health News:Jvion Showcased as Leader in the Predictive Analytic Market 2Health News:West Cancer Center Announces 2nd Annual Ride to Fight On 2Health News:West Cancer Center Announces 2nd Annual Ride to Fight On 3Health News:King Kullen Honors National Hot Dog and Blueberry Month 2Health News:King Kullen Honors National Hot Dog and Blueberry Month 3
... -- Americans who were jobless for longer than 25 weeks ... those who were continuously employed to suffer mental health issues ... Being jobless also has a greater psychological impact on people ... with less education, the researchers found. The study involved ...
... help people with Parkinson,s disease improve their gait and balance, ... School of Nursing and Red Hill Studios, a California serious ... three-month research project showed small improvements in walking speed, balance ... the first research team in the United States to receive ...
... (Oct. 19, 2011) -- A review of the genetic ... link between the widely diagnosed neurological disorder and Type ... recent decades. "It appears that both Type 2 ... impaired glucose tolerance and hyperinsulinemia," said Rice University biochemist ...
... -- Men who get moderate amounts of exercise have better ... active, a new study finds. Motility refers to the ... important factor in fertility. The study by researchers at ... samples and information about their physical activity levels. The men ...
... solutions to dangerous water quality issues in refugee camps is ... High Commissioner for Refugees an agreement that will put ... lab and on the ground in Kenya, Uganda, Liberia and ... additional SMU funds, faculty member Andrew Quicksall and his graduate ...
... Society (ACS), the American Society for Colposcopy and Cervical ... (ASCP) have proposed new guidelines for the prevention and ... are now posted for public comment, generally advise that ... their lifetime to better ensure that they receive the ...
Cached Medicine News:Health News:Long-Term Unemployment Can Tax Mental Health 2Health News:Computer games help people with Parkinson's disease 2Health News:Research proposes common link between autism, diabetes 2Health News:Research proposes common link between autism, diabetes 3Health News:Sperm Moves Best for Moderate Exercisers: Study 2Health News:SMU scientists to lead water quality study at UN refugee camps 2Health News:SMU scientists to lead water quality study at UN refugee camps 3Health News:Health groups issue proposed cervical cancer screening guidelines 2Health News:Health groups issue proposed cervical cancer screening guidelines 3
... Quick & Easy Adjustment Of Blade Separation ... And Patient Comfort (Unlike Spring Action Speculum ... The Blades. No Laborious, Tedious, Slow Screw ... , ,Available In Either Solid Blade Or ...
... Hourglass Jaw Design Holds The Lens ... Incision.,Mirror Polished Blades Keep The Optic ... Offers Control Over Release Of The ... From Tilting During Insertion.,Reusable, Autoclaveable, Made ...
... The 0.1mm Pierce Tip Opening ... Flap, Without The Need For A Separate Cystotome. ... Grasping Positions Without Elevating The Incision.,The Distal Jaws ... Blades Help To Prevent Inadvertent Pick Up Of ...
2.5V Halogen source, fiber-optic delivery, 3X magnification, pocket-sized....
Medicine Products: