Navigation Links
Statement from the Cystic Fibrosis Foundation on Promising Phase 2 Clinical Trial Results of Kalydeco and VX-661 (Vertex Pharmaceuticals Inc.)
Date:4/19/2013

BETHESDA, Md., April 19, 2013 /PRNewswire-USNewswire/ -- The Cystic Fibrosis Foundation issued the following statement in response to an announcement by Vertex Pharmaceuticals Inc. regarding promising results from a Phase 2 clinical trial of its cystic fibrosis drug Kalydeco™ in combination with another potential CF therapy, VX-661. The results showed a significant improvement in lung function in people with two copies of the most common CF mutation, Delta F508, who took the combination treatment, compared with those who received a placebo. About 50 percent of people with CF in the United States have two copies of the Delta F508 mutation.

Both Kalydeco and VX-661 are designed to treat the underlying cause of CF, a faulty gene and its protein product, known as CFTR.

"This announcement is more terrific news for the CF community," said Robert J. Beall , Ph.D., president and CEO of the Cystic Fibrosis Foundation. "While these results are still very early, they show that another potential therapy from our ongoing collaboration with Vertex can be combined with Kalydeco to achieve promising improvements in health. The data further validate our strategy of using small molecule compounds to address the basic genetic defect in cystic fibrosis."

The CF Foundation played a key role in the development of Kalydeco and VX-661, as well as other experimental compounds such as VX-809, providing significant scientific, clinical and financial support. Vertex is studying Kalydeco with VX-809 in Phase 3 trials that will enroll about 1,000 people at approximately 200 clinical trial sites in North America, Europe and Australia. "The CF Foundation is deeply grateful to the people with CF, families and medical professionals who have played a role in these studies, and to the Vertex scientists wh
'/>"/>

SOURCE Cystic Fibrosis Foundation
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2

Related medicine technology :

1. Medical Alarm Concepts Files Information Statement and Provides Update on Corporate Activity
2. Joint Statement On The Presidents Budget From The American Society Of Clinical Oncology, Community Oncology Alliance, ION Solutions and The US Oncology Network
3. Receptos Files Registration Statement for Proposed Initial Public Offering
4. Star Scientific, Inc. Issues Statement in Response to Two Plaintiffs Purported Class Action Law Suits and Multiple Press Releases Issued by Plaintiffs Law Firms Trolling for New Clients
5. National Cancer Organizations Issue Joint Statement On Devastating Impact Of Sequestration
6. AUGS Issues Statement Opposing The Restriction Of Surgical Options For Pelvic Floor Disorders
7. Bausch + Lomb Files Registration Statement For Proposed Initial Public Offering
8. CHPA Statement on Statewide South Carolina Consumer Poll
9. Aratana Therapeutics, Inc. Files Registration Statement for Proposed Initial Public Offering
10. Chimerix Files Registration Statement for Proposed Initial Public Offering
11. CHPA Statement on PSE Economic Study By AEI Fellow Alex Brill
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/21/2014)... , Nov. 21, 2014 In September ... Performance Scrubs carried out a new product development plan ... very first "limited edition" lab coat , aptly ... professors of surgery in the world. The new women,s ... unisex predecessors, with a sleek envelope collar, vertical princess ...
(Date:11/21/2014)... MARCOS, Texas , Nov. 21, 2014  World ... hemp containing low THC, announces they are now offering ... comparable to Charlotte,s Web type strains grown in medical ... from other neurological disorders, such as Parkinson,s, MS, and ... for US laws to pass, because imported CBD Oil ...
(Date:11/21/2014)...  Abaxis, Inc. (NasdaqGS: ABAX ), a ... the medical, research, and veterinary markets worldwide and providing ... in the United States , announced ... acquire 100% of QCR & Trio Diagnostics Limited, a ... The transaction closed on November 17, 2014. ...
Breaking Medicine Technology:Medelita Introduces Medical Industry's First Limited Edition Women's Designer Lab Coat 2New CBD Oil From Industrial Hemp is Comparable to Charlotte's Web, Legal In All 50 States 2New CBD Oil From Industrial Hemp is Comparable to Charlotte's Web, Legal In All 50 States 3Abaxis Acquires UK-based Distribution Organization 2Abaxis Acquires UK-based Distribution Organization 3Abaxis Acquires UK-based Distribution Organization 4
... Inc. (NYSE: HSP ), the world leader in ... with South Korea-based Celltrion, Inc. and Celltrion Healthcare, Inc. ... distribution agreement for the United States, Europe, Australia, New ... currently under development by Celltrion, five of which are ...
... today announced the company won a Gold 2009 International ... process used in the development of the HARMONIC FOCUS(TM) ... of entries for its innovative use of four types ... globe to identify specific unmet needs in thyroid procedures, ...
Cached Medicine Technology:Hospira, Celltrion, Enter Business Cooperation Agreement to Develop and Market Biogeneric Drugs 2Hospira, Celltrion, Enter Business Cooperation Agreement to Develop and Market Biogeneric Drugs 3Ethicon Endo-Surgery Wins Prestigious International Design Award for Innovative Development of HARMONIC FOCUS(TM) 2Ethicon Endo-Surgery Wins Prestigious International Design Award for Innovative Development of HARMONIC FOCUS(TM) 3
(Date:11/22/2014)... 2014 Cancer researchers in New York ... intercellular communication tunnels and the growth and spread of ... on the Surviving Mesothelioma website. , Doctors ... of Minnesota have just released their study on tunneling ... between cells. They found that mesothelioma cells ...
(Date:11/22/2014)... BambooFlooringChina.com is a famous brand in the ... new collection of bamboo mats ; the new models ... , According to the sales manager of BambooFlooringChina.com, ... a highly renewable resource. Their bamboo mats are 100% made ... comes from natural bamboo with caramel bamboo strips. ...
(Date:11/22/2014)... In order to provide better services, LunaDress has ... dresses. The business knows that a suitable cocktail party dress ... , Now, the party dresses supplier’s high quality items are ... leading company in fashion industry, LunaDress understands that it is ... So it always raises the professional level and innovation ability. ...
(Date:11/22/2014)... SATURDAY, Nov. 22, 2014 (HealthDay News) -- The wide ... can pose a threat for people with food allergies, ... there are so many types of food allergies that ... over the holidays," Dr. Guha Krishnaswamy, director of allergy ... said in a hospital news release. "If you ...
(Date:11/22/2014)... (PRWEB) November 22, 2014 Recently, UWDress.com ... wedding guest dresses . In addition, the company ... products. , As a leading online supplier of ... of beautiful outfits. The unusual best wedding guest gowns ... Besides the amazing designs, this new selection is famous ...
Breaking Medicine News(10 mins):Health News:Study Links Cellular ‘Tunnels’ to Mesothelioma Proliferation, According to Surviving Mesothelioma 2Health News:Trendy Bamboo Mats Online Now By BambooFlooringChina.com 2Health News:LunaDress Unveils Fabulous Cocktail Party Dresses 2Health News:'Tis the Season of Challenges for Those With Food Allergies 2Health News:Best Wedding Guest dresses Introduced by UWDress.com 2
... March 19 The Department of Pain Medicine ... a 2009 winner of the American Pain Society,s Center of ... pain centers for excellence and innovation in interdisciplinary care, academic ... many challenges encountered in maintaining a team of professionals able ...
... Harmful to Humans and Property , , ... filed a class action lawsuit in Miami-Dade County Circuit ... purchased defective homes. The Harrells allege that drywall ... neighbors, emits destructive and harmful toxins and renders the ...
... Based on its recent analysis of the field ... Surgical Technology, Inc. with the 2009 North American Technology ... the E-Matrix(TM) tissue scaffold for use in orthopedic and ... with the fact that it provides a suitable matrix ...
... millimeter Custom NX 60 is the world,s longest coronary stent ... Inc. (Nasdaq: XTNT ) today announced that it ... stent (DES) System. The CE Mark indicates that the ... Union as well as other countries that recognize the CE ...
... Friedberg vs. The American Society of Anesthesiologists, Action vs. ... against 43,000 doesn,t seem like very fair odds. Yet, ... surgery anesthesia, Dr. Barry Friedberg, set the stage for ... of Anesthesiologists, (ASA) March 9 press release in which ...
... conducted by the American Society for Aesthetic Plastic Surgery, the number ... 2008. In Maryland, Plastic Surgery Services’ number of ... nationally. , ... Hagerstown MD (PRWeb) March 19, 2009 ...
Cached Medicine News:Health News:The Department of Pain Medicine and Palliative Care at Beth Israel Medical Center is Named 2009 Center of Excellence Award Winner by the American Pain Society 2Health News:Class Action Filed Against South Florida Developer and Supplier of Defective Chinese Drywall 2Health News:Class Action Filed Against South Florida Developer and Supplier of Defective Chinese Drywall 3Health News:Frost & Sullivan Lauds Pioneer Surgical Technology for Development of Tissue Scaffold E-Matrix 2Health News:Frost & Sullivan Lauds Pioneer Surgical Technology for Development of Tissue Scaffold E-Matrix 3Health News:Frost & Sullivan Lauds Pioneer Surgical Technology for Development of Tissue Scaffold E-Matrix 4Health News:XTENT Receives CE Mark Approval for CUSTOM NX (R) Drug-Eluting Stent System 2Health News:XTENT Receives CE Mark Approval for CUSTOM NX (R) Drug-Eluting Stent System 3Health News:Dr. Barry Friedberg comments on David vs. Goliath: Who's Really in the Pursuit of Patient Safety & Satisfaction? 2Health News:Hagerstown Cosmetic Surgeon Weathers the Current Economic Storm Despite the Sharp Decline in the Number of Cosmetic Surgeries Performed Nationwide 2
... The PL-A741 is PixeLINKs most popular machine vision ... FireWire camera with global shutter, external trigger and ... high-quality ditigal video streams to the computer. ... grabber with a CMOS imager to provide a ...
... a 6.6 megapixel color microscopy camera suitable for ... resolution microscopy camera designed to capture publication quality ... and can provide 5 frames per second at ... resolution can be decimated to provide up to ...
... popular microscopy camera. The PL-A662 is a ... for use in brightfield microscopy. The ... Desgined to simplify real-time uncompressed video display ... uncompromising video and digital still-image quality in ...
... camera photomicrographic system can be mounted on ... Leica, Nikon, and Zeiss, making building an ... the Internet easy and fast. Featuring a ... lens. The system records photomicrographic images (2,272 ...
Medicine Products: