Navigation Links
Sorbent Therapeutics Initiates Phase 2b Clinical Trial of CLP-1001 for Treatment of Signs and Symptoms of Fluid Overload in Patients with Heart Failure
Date:4/11/2013

al standard measures of patient quality of life and physical functioning, including 6-Minute Walk Test, body weight, Kansas City Cardiomyopathy Questionnaire, NT-pro BNP and time to first occurrence of HF hospitalization, decongestion therapy, or death.  Secondary objectives for the Phase 2b study are to assess the safety and tolerability of CLP-1001 compared with placebo and to evaluate the effects after eight weeks of treatment on dyspnea (Visual Analog Scale), signs of fluid overload, blood pressure, diuretic dose and New York Heart Association (NYHA) classification.

In Sorbent's previous Phase 2a study, among 111 patients with heart failure, CLP-1001 demonstrated improvements of signs and symptoms of fluid retention, including greater weight loss, improved breathing and average distance walked in the 6-Minute Walk Test versus placebo. 

About Heart Failure
Heart failure is a progressive condition in which the heart muscle becomes weakened after injury, most commonly caused by heart attack or high blood pressure, and gradually loses its ability to pump enough blood to supply the body's needs.  Heart failure affects approximately 7.4 million individuals in the United States annually and the prevalence of heart failure is expected to significantly increase over the next decade.  Despite available therapies, heart failure is the most common cause of hospitalizations in patients 65 years and older in the U.S.

About CLP-1001
CLP-1001 is a first-in-class, non-absorbable, superabsorbent cross-linked polyelectrolyte polymer that acts by removing sodium and fluid via the gastrointestinal tract.  There is a significant need for agents other than diuretics to treat fluid overload associated with heart failure.  Each year there are approximately one million hospitalizations plus re-hospitalizations in the US alone due to fluid overload.  A majority of hospital admissions occur in patie
'/>"/>

SOURCE Sorbent Therapeutics
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Sorbent Therapeutics CLP1001 Improves Heart Failure Symptoms In Phase 2 Clinical Study
2. Sorbent Therapeutics Presents CLP1001 Phase 2a Study Results at the 16th Annual Meeting of the Heart Failure Society of America
3. Sorbent Therapeutics Appoints Jason Levin Chief Business Officer
4. CytoSorbents Receives Approximately $400,000 in Non-Dilutive Capital from the Sale of Net Operating Loss Carryovers
5. Cell Therapeutics, Inc. (CTI) to Report First Quarter Financial Results on April 20
6. Faruqi & Faruqi, LLP Encourages Investors Who Suffered Substantial Losses Investing in Chelsea Therapeutics International, Ltd. to Contact the Firm
7. Argos Therapeutics Secures $25 million Series D Financing to Commence Phase 3 ADAPT Study in Patients with Metastatic Renal Cell Carcinoma (mRCC) in Mid-2012
8. Novelos Therapeutics Announces Successful Completion of First Cohort In Lung Cancer Trial With I-124-CLR1404 (LIGHT) Cancer-Targeted PET Imaging Agent at UW Carbone Cancer Center
9. Zacks Industry Outlook Highlights: Eli Lilly, Forest Labs, ViroPharma, Novartis and United Therapeutics
10. Oxford BioTherapeutics Appoints Senior Industry Leader to Head its New Clinical Development Operations in Basel, Switzerland
11. Nektar Therapeutics Reports Financial Results for the First Quarter of 2012
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/24/2015)... , April 24, 2015   Vestagen Technical Textiles, ... VESTEX ® , has recently received two notable innovation ... global competition that recognizes innovations with potential to create ... last night in New York City ... Material Science "Protection & Safety" category. The awards honor ...
(Date:4/24/2015)... Research and Markets ( http://www.researchandmarkets.com/research/pmbmv2/global_biobanking ) ... Market 2015-2019" report to their offering. ... at a CAGR of 7.07% over the period 2014-2019 ... into two segments: Equipment and Consumables. This report covers ... Global Biobanking market for the period 2015-2019. ...
(Date:4/24/2015)... EAST HANOVER, N.J. , April 24, 2015  Novartis ... diversity for the second year in a row on the ... the results of its 2015 Top 50 Companies for Diversity ... New York, NY . NPC also ranked second on ... on the Top 10 Companies for Employee Resource Groups list. ...
Breaking Medicine Technology:VESTEX Wins Innovation Honors from Edison Awards & Apparel Magazine 2VESTEX Wins Innovation Honors from Edison Awards & Apparel Magazine 3Global Biobanking Market Report 2015-2019 - Increase in Strategic Collaborations with Beckman Coulter, Tecan & Thermo Fischer Scientific Dominating 2Novartis Pharmaceuticals Corporation is first company to receive number one ranking two years in a row on DiversityInc Top 50 Companies for Diversity list 2Novartis Pharmaceuticals Corporation is first company to receive number one ranking two years in a row on DiversityInc Top 50 Companies for Diversity list 3Novartis Pharmaceuticals Corporation is first company to receive number one ranking two years in a row on DiversityInc Top 50 Companies for Diversity list 4
(Date:4/24/2015)... Ranch, California (PRWEB) April 24, 2015 ... has a wide range of capabilities and services to ... , Ryadon's Quantity Discount Program will be offered ... as follows: , Order 4-19: Receive 10% discount - ... Benefit by Using the Drawer Slides Products, ...
(Date:4/24/2015)... TX (PRWEB) April 24, 2015 The Fastest ... Long, after their great success of the Xtreme Fat Loss ... industry. The fat loss blueprint that claims to help ... the attention of HealthyandFitZone.com's Stan Stevenson, prompting an investigative review. ... shows that the creators spent years researching and experimenting with ...
(Date:4/24/2015)... CO (PRWEB) April 24, 2015 The ... have toured almost constantly across the globe to theaters, festivals ... home in Manchester, they’ve partnered with their label, Dirty Hit ... , Teaming up with the newly launched Cadence & ... of their debut LP on vinyl and a signed photo ...
(Date:4/24/2015)... 24, 2015 The first step to ... mind. , For meditation and yoga teacher Stine Koppernæs, ... been invaluable tools that allow her to experience more ... has been a teacher since 2006, and through the ... state of being. , “I love sharing this way ...
(Date:4/24/2015)... Carinsurancequotesinfo.com has released a new blog post ... qualify for auto insurance as a single ... insurance online, without having to follow a special process. ... can reduce their auto insurance expenses. The tips are ... , Clients can now visit an insurance brokerage ...
Breaking Medicine News(10 mins):Health News:Ryadon Inc. Offers Quantity Drawer Slide Discount Program Nationwide in May 2015 2Health News:Ryadon Inc. Offers Quantity Drawer Slide Discount Program Nationwide in May 2015 3Health News:Fastest Fat Loss Week Ever Review Revealed on Healthy & Fit Zone 2Health News:Internationally Recognized British Indie Rock Outfit The 1975 Partner with Cadence & Cause to Provide Clean Drinking Water to Those in Need 2Health News:Auto Insurance Discounts for Single Parents - How to Qualify for Low Rates 2
... rapid detection of bacterial pathogens are crucial to ... from the School of Science at Indiana University-Purdue ... at Purdue University have developed a novel approach ... in food. The investigators have designed and implemented ...
... tissues in our body, can make almost anything, given ... Rockefeller University shows that having too many stem cells, ... increase the odds of developing cancer. By identifying a ... for blood, or hematopoietic stem cells, the work is ...
... THURSDAY, Oct. 14 (HealthDay News) -- Only one in five ... cancer screening guidelines, a new report finds. Some 40 ... remaining 40 percent don,t follow guidelines for any colon cancer ... done to understand how to improve colorectal cancer screening," concluded ...
... blood is famously fraught with fats; now researchers have ... these lipids actually are. A national research team, led ... School of Medicine, has created the first "lipidome" of ... species circulating in human blood. "Everybody knows about ...
... Personalized medicine improving the fit between patient and ... in fields from cancer treatment to the psychopharmacology of ... genetic makeup renders him either more or less sensitive ... unique genotype also determine the effectiveness of preventative or ...
... an Emory University surgeon have received a $1.2 million grant ... project to study discharge decisions at hospitals. GSU Economics ... in the Andrew Young School of Policy Studies, and John ... the three year award from NIH,s National Institute on Aging. ...
Cached Medicine News:Health News:Eat safer: Novel approach detects unknown food pathogens 2Health News:Gene identified that prevents stem cells from turning cancerous 2Health News:Gene identified that prevents stem cells from turning cancerous 3Health News:Most Doctors Don't Follow Colon Cancer Screening Guidelines 2Health News:Most Doctors Don't Follow Colon Cancer Screening Guidelines 3Health News:Researcher find fats galore in human plasma 2Health News:Perspectives on improving patient care: Genetics, personalized medicine, and behavioral intervention 2
... pro Electronic Pipette is ideal for all ... easy-to-follow display, ergonomically-placed operating buttons, and various ... pipetting and diluting make this a lab ... of a manual pipette without any adverse ...
... Pick one of our pipettors up and ... and ejector positionsright where they should beeven if ... designed to help avoid repetitive stress injuries caused ... The Palm Of Your Hand Start dispensing ...
... Ergonomic Design for Unparalleled Comfort ... it. Notice the balance. Notice the trigger and ... left-handed. Thats because our pipettors are ergonomically designed ... long hours of pipetting. Productivity In The ...
... Unparalleled Comfort Pick one of our pipettors ... the trigger and ejector positionsright where they should ... are ergonomically designed to help avoid repetitive stress ... Productivity In The Palm Of Your Hand ...
Medicine Products: