Navigation Links
Sorbent Therapeutics Initiates Phase 2b Clinical Trial of CLP-1001 for Treatment of Signs and Symptoms of Fluid Overload in Patients with Heart Failure
Date:4/11/2013

al standard measures of patient quality of life and physical functioning, including 6-Minute Walk Test, body weight, Kansas City Cardiomyopathy Questionnaire, NT-pro BNP and time to first occurrence of HF hospitalization, decongestion therapy, or death.  Secondary objectives for the Phase 2b study are to assess the safety and tolerability of CLP-1001 compared with placebo and to evaluate the effects after eight weeks of treatment on dyspnea (Visual Analog Scale), signs of fluid overload, blood pressure, diuretic dose and New York Heart Association (NYHA) classification.

In Sorbent's previous Phase 2a study, among 111 patients with heart failure, CLP-1001 demonstrated improvements of signs and symptoms of fluid retention, including greater weight loss, improved breathing and average distance walked in the 6-Minute Walk Test versus placebo. 

About Heart Failure
Heart failure is a progressive condition in which the heart muscle becomes weakened after injury, most commonly caused by heart attack or high blood pressure, and gradually loses its ability to pump enough blood to supply the body's needs.  Heart failure affects approximately 7.4 million individuals in the United States annually and the prevalence of heart failure is expected to significantly increase over the next decade.  Despite available therapies, heart failure is the most common cause of hospitalizations in patients 65 years and older in the U.S.

About CLP-1001
CLP-1001 is a first-in-class, non-absorbable, superabsorbent cross-linked polyelectrolyte polymer that acts by removing sodium and fluid via the gastrointestinal tract.  There is a significant need for agents other than diuretics to treat fluid overload associated with heart failure.  Each year there are approximately one million hospitalizations plus re-hospitalizations in the US alone due to fluid overload.  A majority of hospital admissions occur in patie
'/>"/>

SOURCE Sorbent Therapeutics
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Sorbent Therapeutics CLP1001 Improves Heart Failure Symptoms In Phase 2 Clinical Study
2. Sorbent Therapeutics Presents CLP1001 Phase 2a Study Results at the 16th Annual Meeting of the Heart Failure Society of America
3. Sorbent Therapeutics Appoints Jason Levin Chief Business Officer
4. CytoSorbents Receives Approximately $400,000 in Non-Dilutive Capital from the Sale of Net Operating Loss Carryovers
5. Cell Therapeutics, Inc. (CTI) to Report First Quarter Financial Results on April 20
6. Faruqi & Faruqi, LLP Encourages Investors Who Suffered Substantial Losses Investing in Chelsea Therapeutics International, Ltd. to Contact the Firm
7. Argos Therapeutics Secures $25 million Series D Financing to Commence Phase 3 ADAPT Study in Patients with Metastatic Renal Cell Carcinoma (mRCC) in Mid-2012
8. Novelos Therapeutics Announces Successful Completion of First Cohort In Lung Cancer Trial With I-124-CLR1404 (LIGHT) Cancer-Targeted PET Imaging Agent at UW Carbone Cancer Center
9. Zacks Industry Outlook Highlights: Eli Lilly, Forest Labs, ViroPharma, Novartis and United Therapeutics
10. Oxford BioTherapeutics Appoints Senior Industry Leader to Head its New Clinical Development Operations in Basel, Switzerland
11. Nektar Therapeutics Reports Financial Results for the First Quarter of 2012
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/26/2014)... 2014 Halozyme Therapeutics, Inc. (NASDAQ: HALO ... in New York on Wednesday, December ... Dr. Helen Torley , President and Chief Executive Officer, ... be webcast through the "Investors" section of Halozyme,s corporate website ... available for 90 days following the event. To access the ...
(Date:11/26/2014)... -- China Nepstar Chain Drugstore Ltd. (NYSE: NPD ... chain in China based on the number of directly ... the third quarter ended September 30, 2014. Financial ... store sales increased by 8.1% compared to the third ... to RMB738.3 million (US$120.3 million) compared to RMB683.2 million in ...
(Date:11/24/2014)... Pharmaceuticals, Inc. (NASDAQ: ARNA ) announced today that the ... at the Piper Jaffray 26 th Annual Healthcare Conference ... (5:30 a.m. Pacific Time), at The New York Palace Hotel ... live audio webcast of the presentation will be available under ... . A replay of the presentation will be available for ...
Breaking Medicine Technology:Halozyme Therapeutics To Present At The Piper Jaffray Healthcare Conference 2China Nepstar Chain Drugstore Ltd. Reports Third Quarter 2014 Financial Results 2China Nepstar Chain Drugstore Ltd. Reports Third Quarter 2014 Financial Results 3China Nepstar Chain Drugstore Ltd. Reports Third Quarter 2014 Financial Results 4China Nepstar Chain Drugstore Ltd. Reports Third Quarter 2014 Financial Results 5China Nepstar Chain Drugstore Ltd. Reports Third Quarter 2014 Financial Results 6China Nepstar Chain Drugstore Ltd. Reports Third Quarter 2014 Financial Results 7China Nepstar Chain Drugstore Ltd. Reports Third Quarter 2014 Financial Results 8China Nepstar Chain Drugstore Ltd. Reports Third Quarter 2014 Financial Results 9China Nepstar Chain Drugstore Ltd. Reports Third Quarter 2014 Financial Results 10China Nepstar Chain Drugstore Ltd. Reports Third Quarter 2014 Financial Results 11Arena Pharmaceuticals to Present at Piper Jaffray 26th Annual Healthcare Conference 2Arena Pharmaceuticals to Present at Piper Jaffray 26th Annual Healthcare Conference 3
... SUTIMCo International, Inc. (Pink Sheets: SUTI ) ... corporate executive to the 125th Annual Meeting of The ... in New Orleans.   For over a century, AOAC ... well as proficiency testing and accreditation programs for laboratories. ...
... 2011 HemaQuest Pharmaceuticals, Inc. (HemaQuest), a biotechnology company ... disorders, announced today that it has completed enrollment in ... patients with sickle cell disease. The study, initiated in ... patients in clinical sites in the US, Canada, Jamaica, ...
Cached Medicine Technology:SUTIMCo International Inc. to Attend 125th AOAC Annual Meeting 2SUTIMCo International Inc. to Attend 125th AOAC Annual Meeting 3HemaQuest Pharmaceuticals Completes Patient Enrollment in Phase 2 Clinical Study of HQK-1001 in Patients With Sickle Cell Disease 2HemaQuest Pharmaceuticals Completes Patient Enrollment in Phase 2 Clinical Study of HQK-1001 in Patients With Sickle Cell Disease 3
(Date:11/26/2014)... (PRWEB) November 26, 2014 Gone are the ... cheap deals on Black Friday, which signifies the beginning of ... items into their shopping carts in the comfort of their ... , This Friday is going to be an occasion ... day, with an estimated $2.48 billion in revenue for online ...
(Date:11/26/2014)... With a redesign of the practice website, ... has enhanced the user experience and functionality of the ... online destination for orthopedic and sports medicine knowledge and ... and improved version of the website. The new ... for current and prospective patients to find answers and ...
(Date:11/26/2014)... the video interviewing specialist, has today announced the appointment ... Officer, in addition to the formal opening of it’s ... appointed as Chief Operating Officer. He is joined by ... Officer. , Mr Jones is a seasoned tech, media ... with The Walt Disney Company and Adventis where he ...
(Date:11/26/2014)... Medical suction and vacuum products have a ... score represents steady growth in the price of medical ... a result of swelling demand for healthcare services and ... considered nondiscretionary. IBISWorld market research analyst, Anna Son, says, ... of flexibility, given the low level of price volatility ...
(Date:11/26/2014)... (PRWEB) November 26, 2014 News ... showcase expanded capabilities at RSNA 2014 in Chicago. ... manage and share diagnostic images, photos, videos and ... Perceptive’s booth #8107 will learn more about these ... acquired technologies and partner initiatives – that enable ...
Breaking Medicine News(10 mins):Health News:2014 Best Friday Deals Revealed by Top10InAction 2Health News:Los Angeles Orthopedic Surgeon Dr. Steven Meier Announces Relaunch Of Practice Website 2Health News:Sonru Expansion continues with appointment of new executive team and opening of new London base 2Health News:Medical Suction & Vacuum Products Procurement Category Market Research Report from IBISWorld has Been Updated 2Health News:Medical Suction & Vacuum Products Procurement Category Market Research Report from IBISWorld has Been Updated 3Health News:Medical Suction & Vacuum Products Procurement Category Market Research Report from IBISWorld has Been Updated 4Health News:Perceptive Software to Demonstrate New Medical Content Management Features and Capabilities at RSNA 2014 2Health News:Perceptive Software to Demonstrate New Medical Content Management Features and Capabilities at RSNA 2014 3
... a Perspective on ,An Inspired Life, , , ... a national non-profit organization that seeks to safeguard patients ... employment and preservation of their financial stability relative to ... is pleased to announce that Elizabeth Edwards, an accomplished ...
... with the FDA on Product Safety Concerns, Continues to be ... , SCOTTSDALE, Ariz., June 24 Matrixx Initiatives, Inc. (Nasdaq: ... the process of formally notifying retailers, wholesalers and distributors nationwide ... and Zicam Cold Remedy Gel Swabs. Matrixx Initiatives vigorously ...
... U.S. initiative to provide building managers with required documentation ... certification , , xpedx exhibits at BOMA International ... June 24 xpedx(R), one of the largest U.S. ... show property owners and managers across the nation how ...
... , , , Chocolate and Candy Remain Recession ... Experimenting with flavors, flexibility and variety, confectionery makers are ... candy innovation that will drive consumer purchasing over the next ... Industry Trend Report 2009. Even in economic uncertainty, the industry ...
... OSLO, June 24 DiaGenic ASA (OSL: ... with Merz Pharmaceuticals,GmbH, an innovative developer of drugs for ... to biomarkers for Mild Cognitive,Impairment (MCI), increasingly considered a ... be used to identify patients with MCI,prone to converting ...
... Pulse oximetry is often referred to as the fifth ... hospitals and other critical care settings cannot be doubted. ... past couple of years and recent advances have made ... also more accurate. However, the pulse oximetry market faces ...
Cached Medicine News:Health News:Elizabeth Edwards to Deliver Keynote Address at Patient Advocate Foundation's 10th Annual Patient Congress 2Health News:Matrixx Initiatives Confirms Voluntary Recall of Zicam Cold Remedy Nasal Gel, Zicam Cold Remedy Gel Swabs 2Health News:Matrixx Initiatives Confirms Voluntary Recall of Zicam Cold Remedy Nasal Gel, Zicam Cold Remedy Gel Swabs 3Health News:Matrixx Initiatives Confirms Voluntary Recall of Zicam Cold Remedy Nasal Gel, Zicam Cold Remedy Gel Swabs 4Health News:xpedx Shows U.S. Property Managers and Owners How to Achieve Building Health and Environmental Goals Without Increasing Total Cleaning Costs 2Health News:xpedx Shows U.S. Property Managers and Owners How to Achieve Building Health and Environmental Goals Without Increasing Total Cleaning Costs 3Health News:Confectionery Industry Forecast Is Sweet: Globally Inspired Flavors, Eco-Friendly and Health Minded Trends Lead New Product Innovations 2Health News:Confectionery Industry Forecast Is Sweet: Globally Inspired Flavors, Eco-Friendly and Health Minded Trends Lead New Product Innovations 3Health News:Confectionery Industry Forecast Is Sweet: Globally Inspired Flavors, Eco-Friendly and Health Minded Trends Lead New Product Innovations 4Health News:Confectionery Industry Forecast Is Sweet: Globally Inspired Flavors, Eco-Friendly and Health Minded Trends Lead New Product Innovations 5Health News:Confectionery Industry Forecast Is Sweet: Globally Inspired Flavors, Eco-Friendly and Health Minded Trends Lead New Product Innovations 6Health News:DiaGenic to Provide MCI Biomarkers for Merz Pharmaceuticals 2Health News:DiaGenic to Provide MCI Biomarkers for Merz Pharmaceuticals 3Health News:Pulse Oximetry Entrenched as Standard-of-Care in Patient Monitoring, States Frost & Sullivan 2Health News:Pulse Oximetry Entrenched as Standard-of-Care in Patient Monitoring, States Frost & Sullivan 3Health News:Pulse Oximetry Entrenched as Standard-of-Care in Patient Monitoring, States Frost & Sullivan 4
... assays, the NOVOstar provides both fluorescence and ... of an on-board reagent pipet. The pipet ... or from three reagent stations to the ... two injectors that can accurately deliver reagents ...
... Detection of PCR, cDNA and Oligonucleotides The ... reader for a variety applications that are quantified ... suitable to handle assays in Microplate formats ... tubes Cuvettes Independent whether you ...
This new dedicated VICTOR2 model is for fluorescence and luminescence measurements....
... VICTOR2 V measures ... polarization, luminescence, time-resolved ... absorbance. A red-sensitive ... assay. All technologies ...
Medicine Products: