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SANYO Installs First Cell Processing Work Station in the United States at University of Alabama at Birmingham
Date:6/8/2011

e a significant contribution to advancing research in the cell therapy market, impacting both private and public institutions within the life science, research, biotechnology and pharmaceutical markets. Current and future applications of the CPWS include preclinical regenerative cell therapy research for organ and tissue repair and immunotherapies for treating cancer. Additional opportunities for the CPWS include the pharmaceutical bioprocessing market.

Application of Positive Pressure-type CPWS at the University of Alabama at Birmingham

The nation's first CPWS installed at the University of Alabama at Birmingham, will be used to manufacture induced pluripotent stem (iPS) cells and gamma-delta T cells for research use. iPS cells are non-embryonic stem cells that will be studied as a cure for sickle cell anemia. Gamma-delta T cells will be studied for treating cancer. The CPWS offers UAB enhanced biosafety and enhanced aseptic processing for the GMP compliant manufacture of these and additional cell therapy research.

"The CPWS allows seamless preparation of cell and gene therapy products in a totally contained temperature controlled aseptic environment, drastically reducing the risk of microbial contamination," said Larry Lamb, Ph.D., director of the UAB Cell Therapy Lab, which houses the SANYO CPWS. "The technology also features the ability to change over the entire system in 90 minutes allowing for multiple cell products to be produced in a single CPWS. The Cell Therapy Laboratory and the UAB Stem Cell Institute envision a variety of therapies that can be derived from iPSc, hence we anticipate that the CPWS will serve this need well into the future."

UAB has been a national leader in the field of therapeutic design for nonmalignant diseases of the blood, such as sickle cell disease, using both conventional gene therapy and iPSc-derived approaches.  Additionally, UAB is among the most active programs in North America for trans
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SOURCE SANYO North America Corporation
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