Navigation Links
RNL BIO filed Phase II/III Clinical Trial with KFDA to Treat Cerebral Palsy Using Autologous Fat Derived Stem Cells
Date:2/8/2013

SEOUL, South Korea, Feb. 8, 2013 /PRNewswire/ -- RNL BIO CO LTD (RNL) announced today the filing of an Investigational New Drug (IND) application with the Korean Food and Drug Administration (KFDA) to initiate clinical trials phase II and III assessing the company's RNL-Astrostem™ stem cell drug in patients with cerebral palsy. The purpose of this study is to assess conclusive efficacy of stem cells for the treatment of cerebral palsy in 45 subjects over 11 months.  The study is to be conducted through Kyung Hee University Hospital at Gangdong and THE Bethesda Hospital.

RNL-Astrostem™, has already completed a phase I trial to assure safety, including tests to rule out toxicity or tumorigenicity.  This trial was conducted at the Seoul National University's Clinical Research Institute.  In addition, the phase I study has confirmed the safety of stem cells infused by IV, as published in a leading peer-reviewed journal, Stem Cells and Development ("Safety of intravenous infusion of human adipose tissue-derived mesenchymal stem cells in animals and humans," February 2011). In the course of successful safety trials, scientists found significant evidence suggesting the potential for efficacy of stem cells in treatment of cerebral palsy. In addition, a case report with obvious result of improvement was published in another internationally renowned journal. RNL BIO believes that with successful trials and approval of the KFDA, it will be possible to commercialize RNL-Astrostem™ by 2014, revolutionizing the possibility to cure this incurable disease of children, which can only be managed with current technologies.

Cerebral Palsy is caused by non-progressive brain damage from single or multiple defect(s) on the nerve/muscular system and results in disorder in motion and sensory integration. According to Health Insurance Review and Assessment Service, the prevalence of cerebral palsy is 3.5 pe
'/>"/>

SOURCE RNL BIO
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2

Related medicine technology :

1. Faruqi & Faruqi, LLP Notifies Investors of June 4, 2012 Lead Plaintiff Deadline for the Class Action Filed Against Chelsea Therapeutics International
2. Sosei Group Corporation: QVA149 Filed as a Once-Daily Maintenance Treatment for COPD in Europe
3. Sosei Group Corporation: QVA149 Filed by Licensing Partner as a Once-Daily Maintenance Treatment for COPD in Japan
4. Bernstein Liebhard LLP Announces That A Class Action Has Been Filed Against Abiomed, Inc.
5. Halozyme Announced Roche Filed A Marketing Authorization Application For Subcutaneous MabThera
6. Lotus Pharmaceutical Company Inc. Filed Its Abbreviated New Drug Application (ANDA) Containing a Paragraph IV Certification for a Generic Version of Xenical(R) with the U.S. Food & Drug Administration (FDA)
7. Argos Therapeutics Secures $25 million Series D Financing to Commence Phase 3 ADAPT Study in Patients with Metastatic Renal Cell Carcinoma (mRCC) in Mid-2012
8. Anthera Announces the Completion of Patient Dosing in Phase 2b PEARL-SC Study
9. Omthera Pharmaceuticals Announces Positive Top-Line Results from Phase 3 EVOLVE Study
10. Retrospective Study Suggests that Stereotactic Ablative Radiotherapy (SABR) Can be a Viable Option for Treating Early-Stage Lung Cancer in Operable as well as Inoperable Patients; Phase III Randomized Trial Now Under Way
11. Ultragenyx Announces Phase 1 Results of UX001 in Hereditary Inclusion Body Myopathy (HIBM), a Rare Neuromuscular Disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/15/2014)... , Sept. 16, 2014  Bayer HealthCare and ... Finland , have begun to ... ODM-201, an investigational oral androgen receptor inhibitor in ... in men with castration-resistant prostate cancer who have ... detectable metastases. The trial is designed to determine ...
(Date:9/15/2014)... Sept. 15, 2014 /PRNewswire/ -  Pivotal Therapeutics Inc. ... pharmaceutical company with a focus on Omega-3 therapies ... that the Board of Directors approved the granting ... advisor at the close of business on Friday, September ... 1,000,000 common shares of the Company were granted ...
(Date:9/15/2014)... Sept. 15, 2014 /PRNewswire-iReach/ -- On September 8, ... South Carolina, submitted a Citizen Petition to Dr. ... FDA to add another Black Box Warning to ... request asks for a Black Box Warning for ... paranoia, suicidal thoughts or acts, loss of consciousness, ...
Breaking Medicine Technology:Bayer and Orion Initiate Phase III Trial of ODM-201 in Men with High-Risk Non-Metastatic Castration-Resistant Prostate Cancer 2Bayer and Orion Initiate Phase III Trial of ODM-201 in Men with High-Risk Non-Metastatic Castration-Resistant Prostate Cancer 3Pivotal Therapeutics Grants Incentive Stock Options 2Quinolone Vigilance Foundation Supports Citizen Petition Requesting Another Black Box Warning for Levaquin, Cipro, Avelox 2Quinolone Vigilance Foundation Supports Citizen Petition Requesting Another Black Box Warning for Levaquin, Cipro, Avelox 3
... , , FARMINGDALE, N.Y., Jan. 8 Misonix, Inc. ... medical device technology, which in Europe is used for the ... has entered into a new, three year distribution agreement with ... Saudi Arabia, for the distribution of the SonaStar(TM) Ultrasonic Surgical ...
... N.Y., Jan. 8 VirtualScopics, Inc. (Nasdaq: VSCP ... trials, announced today that Ms. Molly Henderson, the company,s ... corporate overview at the upcoming OneMedPlace Finance Forum at ... annually, the OneMedPlace Finance Forum was created to connect ...
Cached Medicine Technology:Misonix Announces New Distribution Agreement for Kingdom of Saudi Arabia 2Misonix Announces New Distribution Agreement for Kingdom of Saudi Arabia 3VirtualScopics to Present at the Upcoming OneMedPlace Investment Conference 2VirtualScopics to Present at the Upcoming OneMedPlace Investment Conference 3
(Date:9/15/2014)... 2014 Crosley Law Firm is proud to ... have been named to the list of Super Lawyers in ... of personal injury law. , Before receiving the designation ... selection process. First, they must come highly recommended by a ... noteworthy achievement during the past year by obtaining certain honors, ...
(Date:9/15/2014)... Imaging can be a cost-effective way ... benefit from aggressive intervention, according to a new modeling ... The study looked at people with asymptomatic carotid artery ... blood to the head due to atherosclerosis, or plaque ... up to 20 percent of ischemic strokes, which result ...
(Date:9/15/2014)... Authors Christine Snow and Donna Albury highlight ... four alcoholics. Born out of love and pain and the ... In The Life... ” (published by Xlibris) reveals the struggles ... from the same fate. , Night life is popular ... in this. This book chronicles a typical night in the ...
(Date:9/15/2014)... researchers at the University of Copenhagen have gained ... Parkinson,s disease. The findings have recently been published ... , The defining symptoms of Parkinson,s disease ... is currently no cure for the condition, so ... the potential to shed some light on this ...
(Date:9/15/2014)... 2014 DISCcert, a San Diego based ... DISC Certification Workshop for Oct 16th and 17th. ... to take part in the intensive and highly regarded ... activities that can be immediately implemented into their business ... to educate employees and staff in DISC skills. Learning ...
Breaking Medicine News(10 mins):Health News:Thomas A. Crosley and R. Andrew Rodriguez Named 2014 Super Lawyers 2Health News:RSNA: Imaging Identifies Asymptomatic People at Risk for Stroke 2Health News:RSNA: Imaging Identifies Asymptomatic People at Risk for Stroke 3Health News:Authors show perils of alcohol abuse in new graphic novel 2Health News:Authors show perils of alcohol abuse in new graphic novel 3Health News:Researchers debunk myth about Parkinson's disease 2Health News:DISCcert Announces Two-day DISC Certification Workshop Oct 16 and 17 2Health News:DISCcert Announces Two-day DISC Certification Workshop Oct 16 and 17 3
... are more likely to have their work cited than ... a new study released this week by Rice University,s ... scientists are also more likely to receive greater recognition ... "International Stem Cell Collaboration: How Disparate Policies Between the ...
... Institute of Technology have found support for the theory that ... it stores readily available items. Memory researchers have long debated ... capacity and function of each layer is. In a ... Cognitive Psychology, researchers found that short-term memory is made ...
... new study of a common etiquetteholding a door for someonesuggests ... motivation: to reduce the work for those involved. The research, ... State University, is the first to combine two fields of ... to be published in a forthcoming issue of Psychological ...
... The Nobel prize-winning physicist Richard Feynman once wrote in his ... "When I see equations, I see letters in colors - ... hell it must look like to the students." This neurological ... of "seeing" the letters in colour was a specific form ...
... significantly impacts quality of life for patients after ... Hospital. "Transplant recipients with alcoholic cirrhosis experienced ... reported greater pain and physical limitations than non-alcoholics ... Ford Behavioral Health Services, lead author of the ...
... MESA, Ariz. March 8, 2011 Predictive Biomarker ... produced by Unibioscreen, kills cancer cells. Previous studies ... MCL1 can cause cancer cells to grow out of ... non-profit, Phoenix-based Translational Genomics Research Institute (TGen), co-discovered that ...
Cached Medicine News:Health News:Report: International collaboration between researchers results in greater recognition 2Health News:New study proves the brain has 3 layers of working memory 2Health News:More reasons to be nice: It's less work for everyone 2Health News:Reading in 2 colours at the same time 2Health News:Alcohol abuse history influences quality of life following liver transplant 2Health News:PBS-Bio uncovers how Unibioscreen drug kills cancer 2
... The FoamWrap ACTION Elbow Wrap replaces messy ... players, golfers, and others experiencing epicondylitis. Preferred ... application and non-bulky fit. Two overlay straps ... Breathable, non-slip foam lining holds the Elbow ...
... Brace is designed to handle post-op elbow ... The Bledsoe Extender Arm Brace should be ... of the elbow is desired. In most ... be formed, fitted and adjusted in 5 ...
... lightweight brace allows it to fit easily into ... joint following severe sprains, tendonitis or after cast ... with the ankle and provide optimum medial-lateral support. ... rotational strains on the ankle, and they provide ...
... stretch ankle support helps reduce swelling and minimize ... It is easy to apply - it slips ... fits easily into shoes. It features bilateral ... provide side-to-side support and stability. This is ...
Medicine Products: