Navigation Links
PharmaFocus: Vaccine Adjuvants in Infectious Disease
Date:4/11/2013

/p>

Table 2: Immune Cells and Their Corresponding Toll-like Receptors 15

Table 3: TLR Adjuvant Targets and Ligand Types in Clinical Trials for Infectious Disease Vaccines 24

Table 4: Vaccine Adjuvants – Drivers and Barriers, 2013 27

Table 5: Leading Adjuvants in Clinical Trials for Human Infectious Disease Vaccines 36

Table 6: Product Profile – Aluminum Salts/Alum 38

Table 7: Aluminum Salts/Alum SWOT Analysis, 2013 40

Table 8: Product Profile – Emulsions 42

Table 9: Emulsions SWOT Analysis, 2013 43

Table 10: Product Profile – Particulate Delivery Mechanisms 45

Table 11: Particulate Delivery Mechanisms SWOT Analysis, 2013 46

Table 12: Product Profile – Microbial Derivatives 48

Table 13: Microbial Derivatives SWOT Analysis, 2013 49

Table 14: Product Profile – Oligonucleotides 50

Table 15: Oligonucleotides SWOT Analysis, 2013 52

Table 16: Product Profile – Adjuvant Systems 53

Table 17: GSK's Adjuvant System Portfolio, 2013 53

Table 18: Adjuvant Systems SWOT Analysis, 2013 55

Table 19: Overall Unmet Needs – Current Level of Attainment 56

Table 20: Regulatory Guidelines for the Approval of Adjuvanted Vaccines 72

List of Figures Figure 1: Immune System – Stimulation of Innate and Adaptive Responses 13

Figure 2: Adjuvant Targets – Human Toll-like Receptor Family 23

Figure 3: Adjuvant – Host Immune Response Interactions 35

Figure 4: Chemical Structure of MPL 47

Figure 5: Chemical Structure of Dinitrophenylated CpG ODN 50

Figure 6: WHO Map to Vaccine Adjuvant Usage 69

To order this report:Drug_and_Medication Industry:

SOURCE Reportlinker
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Army Researcher Develops Potential Vaccine Carrier That May Give Stockpiling Efforts A Shot In The Arm
2. Shingles Vaccine is Safe, According to New Study
3. Soligenix Announces Further Progress with ThermoVax™ for Long-Term Vaccine ThermoStability
4. Inovio Pharmaceuticals Granted U.S. Patent Protection for Synthetic Vaccine for Cervical Dysplasia and Cancer
5. Biomedical Advanced Research and Development Authority (BARDA) Exercises Option with Pfenex Inc. To Extend Contract for the Development of a Recombinant Protective Antigen (rPA) Based Anthrax Vaccine
6. Sanofi Pasteur Presents Pediatric Data on Investigational Quadrivalent Influenza Vaccine
7. Generex Announces Presentations of Antigen Express AE37 Breast Cancer Vaccine Data at ASCO 2012
8. Inovio Pharmaceuticals Universal Avian Flu Vaccine Generates Protective Antibody Responses Against Six H5N1 Viruses in Phase I Trial
9. Global Human Vaccines Industry
10. Generex Announces New Members of Antigen Express Scientific Advisory Board for the AE37 Breast Cancer Vaccine
11. HIV Vaccine Trials Network Opens Enrollment for Phase 1 Trial of GeoVax Labs Second Generation HIV Vaccine
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/15/2014)...  In an unprecedented effort to curb the spread of "superbugs" such ... vehicles, an advanced and portable UV germicidal lamp manufactured by MRSA-UV ... In order to prevent EMS paramedics and transport ... West Palm Beach Fire Rescue is the first in ...
(Date:1/15/2014)... R.I. , Jan. 15, 2014 MultiCell Technologies, ... filed a U.S. provisional patent application concerning composition of ... to achieve targeted tumor cell death.  ... small noncoding double stranded RNA molecules (VSRNAs) which interfere ...
(Date:1/15/2014)... , Jan. 15, 2014 The Cadence Fitness ... Fitness Center by the Medical Fitness Association, a non-profit ... achieve their full potential. The Cadence Fitness & Health ... western suburbs and second in the Chicagoland area. ...
Breaking Medicine Technology:Superbugs No Longer Ride In Rescue Vehicles 2MultiCell Technologies Files Patent Application Covering New Class of RNA Therapeutics 2MultiCell Technologies Files Patent Application Covering New Class of RNA Therapeutics 3Cadence Fitness & Health Center Certified as Medical Fitness Facility 2Cadence Fitness & Health Center Certified as Medical Fitness Facility 3
... China Nuvo Solar Energy, Inc. (OTCQB: CNUV) today ... Bluewater Surgical, Inc. to a western distributorship. Bluewater surgical ... medicine, trauma surgery and more to acute care hospitals ... the high priced medical device providers in the marketplace. ...
... 4, 2011 Scrip , a leading global ... philanthropic foundation, the Abbott Fund, with a 2011 ... Scrip,s seventh annual awards ceremony in London ... of the significant results achieved through a decade-long, public-private ...
Cached Medicine Technology:China Nuvo Solar Energy, Inc. Announces Third-Party Distribution Agreement With Bluewater Surgical, Inc. 2China Nuvo Solar Energy, Inc. Announces Third-Party Distribution Agreement With Bluewater Surgical, Inc. 3Abbott Honored With Scrip Award for Leadership in Corporate Social Responsibility 2Abbott Honored With Scrip Award for Leadership in Corporate Social Responsibility 3Abbott Honored With Scrip Award for Leadership in Corporate Social Responsibility 4
(Date:4/23/2014)... unrelated donors was safe and effective in treating ... Clostridium difficile , according to a new pilot ... and available online. Known as fecal microbiota transplantation, ... a colonoscope or a nasogastric tube. The findings ... more readily available to patients. , A growing ...
(Date:4/23/2014)... National Institute of Arthritis and Musculoskeletal and Skin Diseases ... Ross Prize in Molecular Medicine, conferred by the Feinstein ... award will be given on June 9 at the ... scientific presentations by Dr. O,Shea and other prominent researchers. ... , The award, which includes a $50,000 prize from ...
(Date:4/23/2014)... - Purdue University researchers have developed a way to ... by using tiny gold particles with tails of synthetic ... agricultural and biological engineering, used gold nanoparticles to target ... BRCA1 messenger RNA splice variants, which can indicate the ... these mRNA splice variants in a cell can be ...
(Date:4/23/2014)... Rochelle, NY, April 23, 2014Men whose testosterone falls below ... and to be overweight and have heart disease and ... to identify testosterone-deficient men for further testing and possible ... of Men,s Health , a peer-reviewed publication from Mary ... on the Journal of Men,s Health website ...
(Date:4/23/2014)... health benefits of probiotics, antioxidants and other nutritional compounds, ... chemical industry is getting in on the action. But ... so the industry is responding with clinical research to ... in Chemical & Engineering News (C&EN), the ... Melody M. Bomgardner, a senior editor at C&EN, writes ...
Breaking Medicine News(10 mins):Health News:Pilot study suggests ways to widen access to fecal transplants for C. diff infections 2Health News:NIH scientist to receive Ross Prize in Molecular Medicine 2Health News:Gold nanoparticles help target, quantify breast cancer segments in a living cell 2
... are not as stringent as with new medications , TUESDAY, ... Administration may not be as stringent in evaluating devices as ... report in the Dec. 23/30 issue of the Journal ... often sails through based on studies that are not randomized ...
... exist both indoors and outdoors, experts say , TUESDAY, Dec. ... can be challenging for anyone, but they pose extra hazards ... cause of injury-related deaths for adults over age 65 in ... older were treated in emergency departments for falls in 2005, ...
... happen outside the lab, expert says , TUESDAY, Dec. ... disinfectant could cause some germs to develop resistance to ... been proven outside of the laboratory and they don,t ... used properly. "It is OK to use disinfectants. Just ...
... Blood Today, Boost Community Supply and Help Save Lives! , ... its divisions in Manhattan, Long Island, Hudson Valley, Brooklyn/Staten Island, and ... recognition of National Blood Donor Month, and to help save lives. ... Americans would die each year without it, and the only place ...
... , , ... Alcohol Recovery (NIFAR®) is launching a global recovery and ... alcohol abuse. Social media websites and educational web videos ... and evaluate their drinking behavior. , (Photo: ...
... -- The role of pharmacists hasn,t received much attention ... But national and regional studies show that when pharmacists ... costs and improve outcomes. A study on diabetic patients ... Pharmaceutical Sciences identified cost savings with improvements in a ...
Cached Medicine News:Health News:Study Questions FDA Approvals of Cardiac Devices 2Health News:Study Questions FDA Approvals of Cardiac Devices 3Health News:Study Questions FDA Approvals of Cardiac Devices 4Health News:Caution Can Help Keep Elderly Safe During Winter 2Health News:Disinfectant Misuse Might Help Germs Resist Antibiotics 2Health News:Disinfectant Misuse Might Help Germs Resist Antibiotics 3Health News:January Is National Blood Donor Month 2Health News:January Is National Blood Donor Month 3Health News:New 'STOP DRINKING 411' Campaign Promotes Alcohol Recovery and Prevention Via Web Social Media 2Health News:New 'STOP DRINKING 411' Campaign Promotes Alcohol Recovery and Prevention Via Web Social Media 3Health News:Pharmacists improve care of diabetics while cutting costs, UB research shows 2Health News:Pharmacists improve care of diabetics while cutting costs, UB research shows 3
Stainless steel lockable wall display for up to 12 frames....
Omni labs carries an extensive line of frames, lenses, soft contacts, RGP lenses, and many other products and services. It supports Zeiss, American optical, Sola, Rodenstock, Zylowear, Eyewear design...
A compact showcase unit. Made with tempered glass, one, two or three adjustable shelves, a door with a safety lock. Equipped with fluorescent lighting and levelers. Display is available in various si...
Classic is proud to provide top-quality vision eyewear to physicians, health maintenance organizations (HMOs), and numerous state and federal government programs. Classic Laboratory produces over 150...
Medicine Products: