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PharmaFocus: Vaccine Adjuvants in Infectious Disease
Date:4/11/2013

competition in the vaccine adjuvant market. Insightful review of the key industry and governmental drivers, restraints and challenges. Each trend is independently researched to provide qualitative analysis of its implications.

Reasons to buy - Develop and design your in-licensing and out-licensing strategies through a review of pipeline products and technologies, and by identifying the companies with the most robust pipeline.

- Develop business strategies by understanding the trends shaping and driving the global vaccine adjuvant market.

- Drive revenues by understanding the key trends, innovative products and technologies, market segments, and companies likely to impact the global vaccine adjuvant market in future.

- Organize your sales and marketing efforts by identifying the market categories and segments that present maximum opportunities for consolidations, investments and strategic partnerships.

Table of Contents 1 Table of Contents 5

1.1 List of Tables 8

1.2 List of Figures 9

2 Introduction 10

2.1 Catalyst 10

3 Vaccines and the Host Immune Response 11

3.1 Vaccines in Infectious Disease 11

3.2 Host Immune Response 12

3.2.1 Primary Barriers Against Infection 12

3.2.2 Innate Immune System 13

3.2.3 Adaptive Immune System 15

3.3 Vaccine Adjuvants 18

3.3.1 Overview 18

3.3.2 Adjuvant Target: Dendritic Cells 19

3.3.3 Adjuvant Target: Toll-Like Receptors 22

3.3.4 Splenic Involvement in Immune Response 25

3.3.5 Antigen-Depot Effect 25

4 Market Drivers and Barriers 27

4.1 Overview 27

4.2 Drivers 28

4.2.1 Driver: Government initiatives to increase vaccination programs 28

4.2.2 Driver: New routes of administration for vaccines 29

4.2.3 Driver: Rapidly mutating pathogens 29

4.2.4 Driver: Recombinant vaccine technology 30

4.2.5 Driver: Increased research efforts against u
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