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New Data Supports Significant Economic and Clinical Value of MENOPUR(R) in IVF
Date:6/30/2009

ropins in IVF and this work is likely to have a major impact on the decision-making process with respect to IVF treatment. The study showed that HP-hMG is a more attractive option than rFSH within a fixed budget, as it offers considerable cost savings over rFSH, not only in terms of costs per treatment cycle, but also in costs per live births."

Health economic data

The new study determined the cost-effectiveness of different gonadotropins in IVF cycles involving frozen embryo transfers using a simulation model. The economic evaluation compared HP-hMG and rFSH using individual patient data (n=986) pooled from two large, randomised, multi- national, non-inferiority trials (EISG[3] and MERiT[4])[5].

The simulation model used both live-birth data for the compared products and published UK costs of IVF related medical resources. The main objectives were to determine for each patient starting treatment consisting of one fresh and up to two cryo or fresh cycles: (1) number of live-births (2) average cost of treatment; (3) average cost per live-birth; (4) incremental cost-effectiveness; (5) impact of inclusion of maternal and neonatal costs arising from successful pregnancies.

After a sequence of one fresh and up to two frozen or fresh cycles, the cumulative live-birth rate was 53.7% for HP-hMG and 44.6% for rFSH (p<0.005). The use of HP-hMG resulted in a saving of GBP875 per patient cycle, a saving that could finance an additional treatment for every seven treatments delivered.[1] Furthermore, the cost per IVF baby delivered with HP-hMG was GBP11,157, compared with GBP14,227 for rFSH(p<0.001).[1]

Within the context of this economic analysis, HP-hMG offered a superior cost-effectiveness in producing live-births over rFSH in women undergoing conventional IVF and, when available, frozen embryo transfer cycles.[1] Since this study attempts to realistically model the actual situati
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SOURCE Ferring Pharmaceuticals
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