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Metabolic Solutions Development Company Awarded Funding by The Michael J. Fox Foundation
Date:2/7/2013

5 million people globally suffer from Parkinson's disease, a neurodegenerative disorder caused by the diminished production of dopamine, a key neurotransmitter, resulting in progressive impairment of motor function including tremors, rigidity and difficulty in moving. Long-term treatment of Parkinson's disease (PD) patients with levodopa, also called L-dopa, typically leads to unwanted side effects including L-dopa induced dyskinesia (LID), which prevents optimal treatment of the disease.

L-dopa Induced Dyskinesia
Levodopa, also called L-dopa, is the most commonly administered drug to treat Parkinson's symptoms. L-dopa helps restore levels of dopamine, a chemical messenger in the brain responsible for smooth, coordinated movement and other motor and cognitive functions. Dyskinesia is a common side effect of L-dopa treatment. These involuntary, uncontrollable, and often excessive movements are distinct from the rhythmic tremor commonly associated with Parkinson's disease.

About Metabolic Solutions Development Company
Metabolic Solutions Development Company (www.msdrx.com) is a drug discovery and development company investigating novel molecular targets and developing new therapeutics to treat metabolic diseases associated with age-related mitochondrial dysfunction, especially type 2 diabetes.

About The Michael J. Fox Foundation for Parkinson's Research
As the world's largest private funder of Parkinson's research, The Michael J. Fox Foundation is dedicated to accelerating a cure for Parkinson's disease and improved therapies for those living with the condition today. The Foundation pursues its goals through an aggressively funded, highly targeted research program coupled with active global engagement of scientists, Parkinson's patients, business leaders, clinical trial participants, donors and volunteers. In addition to funding more than $313 million in research to date, the Foundation has fundamenta
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