Navigation Links
MedImmune's Motavizumab Reduced RSV Hospitalizations by 83 Percent Among High-Risk Native American, Full-Term Infants in Placebo-Controlled Phase 3 study
Date:8/23/2007

V disease and is administered by intramuscular injection. The safety and efficacy of Synagis were established in infants with bronchopulmonary dysplasia (BPD), infants with a history of prematurity (less than or equal to 35 weeks gestational age), and children with hemodynamically significant congenital heart disease. The first dose of Synagis should be administered prior to commencement of the RSV season, which usually starts in the fall and runs through the spring. Patients, including those who develop an RSV infection, should continue to receive monthly doses throughout the season.

Very rare cases (<1 per 100,000 patients) of anaphylaxis and rare (<1 per 1,000 patients) hypersensitivity reactions have been reported with Synagis. Cases of anaphylaxis were reported following re-exposure to Synagis and rare severe hypersensitivity reactions occurred on initial exposure or re-exposure. If a severe hypersensitivity reaction occurs, therapy with Synagis should be permanently discontinued. If milder hypersensitivity reaction occurs, caution should be used on re-administration of Synagis.

In clinical trials, the most common adverse events occurring at least one percent more frequently in Synagis-treated patients than controls were upper respiratory infection, otitis media, fever and rhinitis. Cyanosis and arrhythmia were seen in children with CHD.

The pivotal trial for Synagis was called the IMpact trial and comprised a total of 1,502 children who were randomized (500 placebo, 1,002 Synagis) in a double-blind, placebo-controlled protocol where 1,486 children completed the study's follow-up.

In the IMpact trial, monthly prophylaxis with Synagis via intramuscular injections was associated with a 55-percent reduction in hospitalization as a result of RSV (p=<0.001). Reductions were observed in both children with bronchopulmonary dysplasia (38 percent reduction) and premature children without BPD (78 percent reduction). Approximately 50 percent of the
'/>"/>

SOURCE MedImmune, Inc.
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. New Study Shows That Extending Prophylaxis With Clexane / Lovenox (enoxaparin Sodium Injection) to 5 Weeks is More Effective Than 10 Days for Reducing the Risk of Venous Thromboembolism (VTE) in Acutely ill Medical Patients With Reduced Mobility
2. Publication on Pixantrone Preclinical Studies Demonstrates Reduced Cardiotoxicity Compared to Equiactive Doses of Doxorubicin and Mitoxantrone
3. New Study Shows A1c Reduced Safely By Patients With Type 2 Diabetes Using Self-Adjusted Dosing Starting With Once-Daily Insulin Treatment Levemir
4. Lipitor Reduced the Risk of Coronary Events by Half and Stroke by Nearly One-Third in High-Risk Patients with Type 2 Diabetes Who Experienced a Recent Stroke
5. New Study Shows A1c Reduced Safely By Patients With Type 2 Diabetes Using Self-Adjusted Dosing Starting With Once-Daily Insulin Treatment Levemir
6. Arterial Plaque Significantly Reduced in Women Age 50-59 Taking Hormones, Says New Analysis of Womens Health Initiative Data
7. New Analysis of WHI Data Shows Reduced Levels of Coronary Artery Calcification, a Predictor of Cardiovascular Events, in Women aged 50-59 taking Estrogen Therapy
8. Pivotal Phase III Trial Showed Promacta (eltrombopag olamine) Raised Platelet Counts and Reduced Bleeding in Patients With Chronic ITP
9. Preclinical Study Finds Protease Inhibitor-Resistant HIV May Have Reduced Potential to Develop Resistance to Panacos Bevirimat
10. New Analysis of Data Shows Treatment With Abbotts Humira (Adalimumab) Significantly Reduced Disease-Related Hospitalization for Patients with Crohns Disease
11. Data Suggest Cymbalta Reduced Severity of Night Pain in Patients with Diabetic Nerve Pain
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/7/2015)... The Global Breast Pumps Market is ... an estimated CAGR of 7.6% from 2014 to 2020, according ... of innovative technologies including hand free breast pumps, growing women ... advantages of breast milk are expected to drive breast pump ... untapped growth opportunities in emerging markets such as ...
(Date:7/7/2015)... China , July 7, 2015 /PRNewswire/ -- Mindray ... a leading developer, manufacturer and marketer of medical ... acquire the remaining stake in Wuhan Dragonbio Surgical ... Dragonbio is a domestic medical ... and other surgical products. Prior to today,s announcement, ...
(Date:7/7/2015)... July 7, 2015 EnteroMedics Inc. (NASDAQ: ... use neuroblocking technology to treat obesity, metabolic diseases, and ... announced public offering of 32,000,000 units. Each unit consists of ... warrant to purchase one share of common stock at ... purchase of units in the offering would result in ...
Breaking Medicine Technology:Breast Pumps Market To Reach $1,197.7 Million By 2020: Grand View Research, Inc. 2Breast Pumps Market To Reach $1,197.7 Million By 2020: Grand View Research, Inc. 3Breast Pumps Market To Reach $1,197.7 Million By 2020: Grand View Research, Inc. 4Mindray Medical to Acquire the Remaining Stake in Wuhan Dragonbio 2Mindray Medical to Acquire the Remaining Stake in Wuhan Dragonbio 3Mindray Medical to Acquire the Remaining Stake in Wuhan Dragonbio 4EnteroMedics Inc. Announces Pricing of $16.0 Million Public Offering of Common Stock and Warrants 2EnteroMedics Inc. Announces Pricing of $16.0 Million Public Offering of Common Stock and Warrants 3
(Date:7/7/2015)... ... July 07, 2015 , ... WiseWear®, a ... launched their first line of luxury smart jewelry called the Socialite™ collection. The ... ship this fall. , “The Socialite collection was crafted to inspire women ...
(Date:7/7/2015)... ... 07, 2015 , ... Leading healthcare consulting firm Hammes Company ... Vice President, heading the firm’s Healthcare Advisory Services division. , Mr. Warden will ... providers’ needs in ways that strengthen their position in the marketplace. The Healthcare ...
(Date:7/7/2015)... ... July 07, 2015 , ... More than ... Dial and Howdy’s, raised more than $524,286 during the Muscular Dystrophy Association's ... $100,000, to help support children fighting muscular dystrophy and related life-threatening diseases ...
(Date:7/7/2015)... New York, NY (PRWEB) , ... July 07, 2015 , ... ... only thing that can help pass those long, stressful days at work is knowing ... vacations aren’t always as laid back and stress free as imagined. Planning for a ...
(Date:7/7/2015)... ... July 07, 2015 , ... ... services, is debuting their brand new website. The website’s goal is to provide ... wider selection of patient tools, including requesting appointments online. , Part of the ...
Breaking Medicine News(10 mins):Health News:WiseWear Unveils Luxury Smart Jewelry Line 2Health News:Hammes Company Hires Jay Warden to Lead Healthcare Advisory Services 2Health News:Hammes Company Hires Jay Warden to Lead Healthcare Advisory Services 3Health News:Western Refining Raises $524,286 to Help Send Kids with Neuromuscular Disease to MDA Summer Camp 2Health News:Western Refining Raises $524,286 to Help Send Kids with Neuromuscular Disease to MDA Summer Camp 3Health News:Difass USA Offers Eight Tips to Help Relax and Enjoy Summer Vacation 2Health News:Difass USA Offers Eight Tips to Help Relax and Enjoy Summer Vacation 3Health News:Northeast Nebraska Imaging Launches New Patient Friendly Website 2
... , SARASOTA, Fla. , Feb. 10 ... is retaining new auditors. This will allow the company to complete the ... become current in its filings to the SEC. , The company would ... January 29th 2010 pursuant to the Form 8K filing. In ...
... understand what factors may influence who contracts tuberculosis (TB)/HIV co-infection ... makeup of the disease, with the majority of cases now ... paper, "HIV and Tuberculosis Co-infection Among Hispanics in Southern California: ... of the American Journal of Public Health. ...
... have double the odds of dying before age 55, study ... are at a greater risk of dying young, a new ... likely to die before age 55 as are normal-weight children. ... leave behind young families, this poses a multigenerational, societal problem, ...
... the eating disorder , WEDNESDAY, Feb. 10 (HealthDay News) -- ... of fat in their bone marrow, U.S. researchers have found. ... extremely low body weight and an obsessive fear of weight ... with almost no subcutaneous [below the skin] fat would be ...
... data from lower Manhattan residents suggest a link, nearly ... -- Nearly 10 years after the 9/11 attacks, residents ... World Trade Center site appear prone to persistent, sometimes ... preliminary," stressed study author Dr. Sara C. Crystal, an ...
... ... documents and,drawings. , ... (PRWEB) February 10, 2010 -- McLaren Software , a leader in asset information management ... ARC Advisory World Industry Forum in Orlando, Florida., , ,Due for release in March 2010, ...
Cached Medicine News:Health News:Whitemark Homes Inc. Announces Change of Auditors and Additional Corporate Information 2Health News:Burden of HIV/TB infections increasingly falling on Hispanic community 2Health News:Premature Death Could Await Obese Kids 2Health News:Premature Death Could Await Obese Kids 3Health News:With Anorexia, Body May Hoard Fat in Bones 2Health News:Exposure to 9/11 Fumes Tied to Chronic Headaches 2Health News:Exposure to 9/11 Fumes Tied to Chronic Headaches 3Health News:McLaren Software Extends the Reach of Asset Document Management Processes 2
...
...
...
... Knee System features both ... replacement options. The centerpiece of ... Hinge Knee, promotes the restoration ... is designed for distribution of ...
Medicine Products: