Navigation Links
MedImmune's Motavizumab Reduced RSV Hospitalizations by 83 Percent Among High-Risk Native American, Full-Term Infants in Placebo-Controlled Phase 3 study
Date:8/23/2007

Native American infants, with an overall incidence and severity of adverse events (AEs) that were similar between the motavizumab and the placebo groups. The mortality rates were not statistically different between groups (0.4 percent in the placebo arm, n=2 and 0.3 percent in the motavizumab arm, n=3) and were not considered to be related to the study drug. As was suggested in the pivotal Phase 3 trial conducted in high-risk, preterm infants, rates of hypersensitivity related skin rashes within two days of dosing were seen in about one percent of treated children in the motavizumab group.

MedImmune's Commitment to RSV Prevention

MedImmune is a world leader in the development of innovative therapeutic biologic products to prevent RSV disease. In 1996, MedImmune launched the first anti-RSV drug, RespiGam(R) (respiratory syncytial virus immune globulin intravenous (human) (RSV-IGIV)), which was a polyclonal antibody administered via four-hour intravenous infusion. In 1998, MedImmune introduced Synagis, which was a significant product improvement as a monthly intramuscular injection for the prevention of severe RSV, as well as being the first MAb to receive U.S. Food and Drug Administration (FDA) approval for an infectious disease. With the development of motavizumab, MedImmune continues to reinforce its commitment to developing anti-RSV products. In a head-to-head comparative Phase 3 trial with Synagis, motavizumab met its primary endpoint of reducing RSV-related hospitalizations in high-risk pediatric patients and met its secondary endpoint of reducing medically attended, outpatient respiratory tract infections in that patient group. MedImmune is also developing a small-molecule product candidate to prevent RSV as well as a vaccine against RSV, both of which are in Phase 1 clinical trials.

About RSV

Each year, up to 125,000 infants in the U.S. are hospitalized with severe RSV infections, the leading cause of lower respiratory tract infections
'/>"/>

SOURCE MedImmune, Inc.
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. New Study Shows That Extending Prophylaxis With Clexane / Lovenox (enoxaparin Sodium Injection) to 5 Weeks is More Effective Than 10 Days for Reducing the Risk of Venous Thromboembolism (VTE) in Acutely ill Medical Patients With Reduced Mobility
2. Publication on Pixantrone Preclinical Studies Demonstrates Reduced Cardiotoxicity Compared to Equiactive Doses of Doxorubicin and Mitoxantrone
3. New Study Shows A1c Reduced Safely By Patients With Type 2 Diabetes Using Self-Adjusted Dosing Starting With Once-Daily Insulin Treatment Levemir
4. Lipitor Reduced the Risk of Coronary Events by Half and Stroke by Nearly One-Third in High-Risk Patients with Type 2 Diabetes Who Experienced a Recent Stroke
5. New Study Shows A1c Reduced Safely By Patients With Type 2 Diabetes Using Self-Adjusted Dosing Starting With Once-Daily Insulin Treatment Levemir
6. Arterial Plaque Significantly Reduced in Women Age 50-59 Taking Hormones, Says New Analysis of Womens Health Initiative Data
7. New Analysis of WHI Data Shows Reduced Levels of Coronary Artery Calcification, a Predictor of Cardiovascular Events, in Women aged 50-59 taking Estrogen Therapy
8. Pivotal Phase III Trial Showed Promacta (eltrombopag olamine) Raised Platelet Counts and Reduced Bleeding in Patients With Chronic ITP
9. Preclinical Study Finds Protease Inhibitor-Resistant HIV May Have Reduced Potential to Develop Resistance to Panacos Bevirimat
10. New Analysis of Data Shows Treatment With Abbotts Humira (Adalimumab) Significantly Reduced Disease-Related Hospitalization for Patients with Crohns Disease
11. Data Suggest Cymbalta Reduced Severity of Night Pain in Patients with Diabetic Nerve Pain
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/2/2015)... , Sept. 2, 2015 Research and ... of the "Medical Device Studies: Clinical Evidence ... to their offering. This course ... involved in gathering clinical evidence required for medical ... required for all medical devices and the emphasis ...
(Date:9/2/2015)... Sept. 2, 2015  Neurocrine Biosciences, Inc. (Nasdaq: ... Chief Financial Officer of Neurocrine Biosciences, will be presenting ... New York City . The live ... ET (8:25am PT).  The presentation will be webcast and ... http://www.neurocrine.com .   Listeners are encouraged to ...
(Date:9/2/2015)... -- Research and Markets ( http://www.researchandmarkets.com/research/r6wspz/drug_delivery_in ) has ... "Drug Delivery in Central Nervous System Diseases ... offering. Advances in understanding of ... new avenues and possibilities for improved drug delivery ... enzymes, and receptors that control the penetration of ...
Breaking Medicine Technology:Medical Device Studies: Clinical Evidence Course - London, UK - November 10-11, 2015 2Drug Delivery in Central Nervous System Diseases - Technologies, Markets and Companies Report 2015-2024 2Drug Delivery in Central Nervous System Diseases - Technologies, Markets and Companies Report 2015-2024 3
... N.H., Dec. 14, 2011 Novocure, a commercial ... of three former senior OSI Pharmaceuticals executives to ... is responsible for bringing the company,s new tumor ...   Peter M. Melnyk has joined ...
... 2011  The editors of IndustryWeek have selected 10 honorees for ... Fame. IndustryWeek is the premiere publication serving executive and ... history of acknowledging the leaders of manufacturing operations through distinguishing ... Best Plants. Through the IW Manufacturing ...
Cached Medicine Technology:Novocure Adds Three Senior Oncology Executives to its Global Management Team 2Novocure Adds Three Senior Oncology Executives to its Global Management Team 3Novocure Adds Three Senior Oncology Executives to its Global Management Team 4National Magazine Inducts 10 Manufacturing Leaders Into the IW Manufacturing Hall of Fame 2National Magazine Inducts 10 Manufacturing Leaders Into the IW Manufacturing Hall of Fame 3National Magazine Inducts 10 Manufacturing Leaders Into the IW Manufacturing Hall of Fame 4
(Date:9/2/2015)... ... 2015 , ... One can hardly argue against the fact that more and ... personal computers. These devices are being used as GPS, to make purchases, and yes, ... apps, STD positive singles can now join the prestigious social ranks of e-dating. ...
(Date:9/2/2015)... ... September 02, 2015 , ... The CRISPR-Cas9 system ... a complex of the Cas9 nuclease with either a chimeric single guide RNA (sgRNA) ... ability of any given guide RNA (sgRNA or crRNA) to create a break in ...
(Date:9/2/2015)... ... September 02, 2015 , ... Healthegy, a leading ... two leaders who will deliver keynote presentations at the upcoming Digital Healthcare Innovation ... Hotel in Boston. , Larry Renfro, CEO of Optum, will deliver the morning ...
(Date:9/2/2015)... (PRWEB) , ... September 02, 2015 , ... Telehealth represents ... Well Corp., contracted to handle the telehealth services of more than 12 Blues plan ... and Blue Shield Plans takes a look this growing trend, interviewing executives at Capital ...
(Date:9/2/2015)... ... , ... Date and time: Oct. 3, 2015, 9 a.m. to 4 p.m. ... Bryn Athyn, Pa 19009 , Cost: $50 per person; includes lunch , The Quakertown, ... author Sam Keen based on his new book which he co-authored with his son, ...
Breaking Medicine News(10 mins):Health News:Herpes-datingsites.com Recently Added Reviews of 5 STD Dating Apps for STD Positive Singles 2Health News:GE Healthcare Webinar Discusses Improvements to CRISPR-Cas9 Gene Editing 2Health News:GE Healthcare Webinar Discusses Improvements to CRISPR-Cas9 Gene Editing 3Health News:GE Healthcare Webinar Discusses Improvements to CRISPR-Cas9 Gene Editing 4Health News:Larry Renfro, CEO of Optum and Jonathan Bush, CEO of AthenaHealth to Address Healthcare Entrepreneurs and Investors at 5th Annual Digital Healthcare Innovation Summit 2Health News:Larry Renfro, CEO of Optum and Jonathan Bush, CEO of AthenaHealth to Address Healthcare Entrepreneurs and Investors at 5th Annual Digital Healthcare Innovation Summit 3Health News:AIS Newsletter Focuses on Growing Telehealth Trend Among Blues Plans 2Health News:AIS Newsletter Focuses on Growing Telehealth Trend Among Blues Plans 3Health News:justCommunity, Inc. and Bryn Athyn Men’s Groups Present Workshop on Family Reconciliation 2
... blood cells immune system ,soldiers, get to the site ... along the lining of the blood vessel gripping it tightly ... the while searching for temporary ,road signs, made of special adhesion ... barrier so they can get to the damaged tissue. ...
... its Industry Quarterly publications focused on recent events ... and healthcare IT industriesWALTHAM, Mass., May 4 ... medical technology market intelligence, has recently released the ... (IQ) publications highlighting the most recent trends ...
... This Mother,s Day, kids of all ages can treat ... visit http://www.hydromassage.com/mothersday to download ... certificate (for the young at heart) that entitles their mom ... are over 700 locations in 49 states participating in the ...
... MMR Information Systems, Inc. (OTC Bulletin Board: MMRF), ... (collectively, "MMR") provides consumer-controlled Personal Health Records ("PHRs") ... deposit box storage solutions ( www.myesafedepositbox.com ... previously filed current report on Form 8-K dated ...
... U.S. experts say , , MONDAY, May 4 (HealthDay News) -- ... to one usually seen in pigs emerges, spreads and sets ... familiar? Just such a swine flu outbreak occurred decades ago, ... such an outbreak doesn,t necessarily lead to mass mortality or ...
... Board of Directors as it Focuses on Continued GrowthSYLMAR, ... nation,s leading specialty distributor of health care products in ... today that it has acquired Blue Ridge Medical, Inc., ... The company plans to merge Blue Ridge with ...
Cached Medicine News:Health News:Weizmann Institute scientists show white blood cells move like millipedes 2Health News:Despite the Economic Downturn, Long-Term Growth Potential in the US Dental Biomaterial Market Remains Robust 2Health News:HydroMassage Lets Kids Treat Mom to Free Massage this Mother's Day 2Health News:MyMedicalRecords, Inc. Stand-Alone Audited Financial Statements for the Period Ending December 31, 2008 to be Filed with the SEC Today, Monday, May 4, 2009 2Health News:MyMedicalRecords, Inc. Stand-Alone Audited Financial Statements for the Period Ending December 31, 2008 to be Filed with the SEC Today, Monday, May 4, 2009 3Health News:MyMedicalRecords, Inc. Stand-Alone Audited Financial Statements for the Period Ending December 31, 2008 to be Filed with the SEC Today, Monday, May 4, 2009 4Health News:MyMedicalRecords, Inc. Stand-Alone Audited Financial Statements for the Period Ending December 31, 2008 to be Filed with the SEC Today, Monday, May 4, 2009 5Health News:MyMedicalRecords, Inc. Stand-Alone Audited Financial Statements for the Period Ending December 31, 2008 to be Filed with the SEC Today, Monday, May 4, 2009 6Health News:1976 Swine Flu Outbreak Offers Echoes, Lessons Today 2Health News:1976 Swine Flu Outbreak Offers Echoes, Lessons Today 3Health News:1976 Swine Flu Outbreak Offers Echoes, Lessons Today 4Health News:Sarnova Announces Acquisition to Expand Bound Tree Medical Business 2Health News:Sarnova Announces Acquisition to Expand Bound Tree Medical Business 3
... opening to block tear drainage through the canaliculus, ... dry eye symptoms:, Indicated for use in ... dry eye components of various ocular surface diseases, ... dry eye related complications and to enhance the ...
The collagen intracanicular plugs have a smooth proprietary finish that simplifies insertion of the plug. Collagen plugs are ideal for short term, diagnostic and post-surgical occlusion. Plugs are 2m...
Form should always follow function. Thats why EagleVision created the FlexPlug, the only tapered shaft punctum plug with contouring traction ribs. Designed to provide the ultimate in flexibility, fix...
... Steerability - Use the Attain Prevail's ... catheters and guide wires, to obtain the ... Inject contrast media for improved visualization of ... needed with tip deflection. Telescoping - ...
Medicine Products: