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Lilly Withdraws Application for Additional U.S. Indication for Cymbalta(R) for Chronic Pain
Date:11/28/2008

that the product will receive regulatory approval for chronic pain, or that it will continue to be commercially successful. For further discussion of these and other risks and uncertainties, see Lilly's filings with the United States Securities and Exchange Commission. Lilly undertakes no duty to update forward-looking statements.

    (i)    Chappell, A. et al. Duloxetine 60 to 120 mg versus Placebo in the
           Treatment of Patients with Osteoarthritis Knee Pain. Poster
           presented at the European League Against Rheumatism. 13 June 2008.
    (ii)   Skljarevski, V. et al. Efficacy of Duloxetine in Chronic Low Back
           Pain.  Poster presented at the European Federation of Neurological
           Societies Annual Congress. 25 August 2008.
    (iii)  Skljarevski, V. et al. Duloxetine versus Placebo in the Treatment
           of Chronic Low Back Pain.  Poster presented at the 12th World
           Congress of Pain. 21 August 2008.
    (iv)   APF 2008.
    (v)    NIH 1998.
    (vi)   Fox et al. 2000.
    (vii)  Stewart et al. 2003.
    (viii) White et al. 2005.

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