Navigation Links
ESBATech's Lead Antibody Fragment Enters Clinical Development for Ophthalmic Indications
Date:4/24/2008

ogy platform for therapeutic antibody fragments, we started preclinical development of ESBA105 in mid 2006. Now to move this swiftly into the clinic is a truly exciting time for the company. ESBA105 represents a new generation of antibody fragment therapeutics that have favourable biochemical properties over earlier classes of antibody fragments, such as high stability, solubility and high monomeric content. This allows us to deliver the drug topically, without any need to stabilize or modify the protein. Thanks to the small protein size as compared to conventional antibodies, ESBA105 efficiently penetrates into all segments of the eye, which results in a high local concentration where the drug is needed to inhibit inflammation. As this is associated with low systemic drug exposure, this novel therapeutic approach has a very low risk of provoking systemic adverse effects."

ESBATech is the first and only company to date that has successfully screened and characterized the entire human pool (1.5 million) of naturally occurring variable immunoglobulin (VH and VL) domains to select highly stable, soluble and monomeric single-chain antibody fragments frameworks. The company is advancing a pipeline of novel, antibody fragment therapeutics for topical and/or local delivery, to ensure safe and convenient patient therapy.

About ESBATech AG

ESBATech AG is a Zurich, Switzerland-based, privately held drug discovery and development company focused on advancing antibody fragments for therapeutic applications. The company applies its proprietary, fully human single-chain antibody frameworks to generate product candidates against targets of clinical relevance. ESBATech is focused on delivering high concentrations of its therapeutic antibody fragments to the targeted sites, in combination with extremely low systemic load, in order to achieve low risk of systemic drug reactions using topical and local delivery. Current venture investors include SV Life Sciences,
'/>"/>

SOURCE ESBATech AG
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Micromet Enrolls First Patient in a Phase 1 Clinical Trial with MT110, the First BiTE Antibody for Treatment of Solid Tumors
2. MedImmune Advances Asthma Program with Start of a Phase 2 Trial in Europe and Australia and First U.S.-Based Clinical Trial for Antibody Targeting IL-13
3. OncoMed Chooses SynCo Bio Partners to Fill and Finish its Lead Antibody
4. Micromet Shows Feasibility of Subcutaneous Delivery of BiTE Antibody in Preclinical Primate Study
5. Genaera Announces MedImmune Initiation of Phase 2a Trial of Antibody Targeting Interleukin-9 in Patients with Asthma
6. MedImmune Advances Clinical Development of Antibody Targeting Interleukin-9 in Patients with Asthma
7. Micromet Announces Presentation of Five Posters Related to Its Proprietary BiTE Antibody Platform at Annual Meeting of American Association for Cancer Research
8. Raven Announces Completion of Enrollment in the Phase 1/2a Clinical Trial of RAV12 Therapeutic Antibody for the Treatment of Adenocarcinomas
9. Micromet Announces the Publication of BiTE Antibody Review in Drugs of the Future
10. Celltrion and CSL Announce Collaboration to Develop and Manufacture Monoclonal Antibody
11. Preclinical Studies Show Promise for Novel Antibody Therapy to Treat Acute Myeloid Leukemia (AML)
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/30/2015)... -- Tianyin Pharmaceutical Inc. (NYSE Amex: TPI ) ... patented biopharmaceutical, modernized traditional Chinese medicine (mTCM), branded generics ... notice it received on May 21, 2015 from the ... was below certain of the Exchange,s continued listing standards, ... the NYSE MKT Company Guide, due to the delay ...
(Date:7/30/2015)... -- Growth of the U.S. nonprescription market is primarily driven ... to the OTC market. Due to an increasingly favorable ... activity over the next five years with several all ... entering the market into existing categories. If ... those with low to moderate likelihood), the market is ...
(Date:7/30/2015)... 30, 2015  Medimetriks Pharmaceuticals, Inc. announced today ... III clinical study for Ozenoxacin, a novel bactericidal ... the exclusive U.S. rights to Ozenoxacin 1% cream.  ... 44 centers with an emphasis on U.S. patients, ... months and older with a clinical diagnosis of ...
Breaking Medicine Technology:TPI Provides Update Regarding Non-Compliance with NYSE MKT Continued Listing Requirements 2Rx-to-OTC Switches -- Game Changers for the U.S. OTC Drugs Market through 2019, Sees Kline 2Rx-to-OTC Switches -- Game Changers for the U.S. OTC Drugs Market through 2019, Sees Kline 3Medimetriks Pharmaceuticals, Inc. Announces Completion of the Second Successful Pivotal Phase III Study for Ozenoxacin 2Medimetriks Pharmaceuticals, Inc. Announces Completion of the Second Successful Pivotal Phase III Study for Ozenoxacin 3
... Jan. 16 Cogentus Pharmaceuticals,Inc. today announced ... study to confirm,the full antiplatelet activity of ... once-daily capsule that combines clopidogrel (currently,marketed by ... with,a gastroprotectant (omeprazole) to improve the gastrointestinal ...
... FRANCISCO, Calif., Jan. 16 Cerimon,Pharmaceuticals, Inc., announced ... II/III clinical studies of its once-,daily topical diclofenac ... One,of the studies, designated the "SUPPORT" (Stop Underlying ... study, will assess the,efficacy and safety of Cerimon,s ...
Cached Medicine Technology:Cogentus Pharmaceuticals Begins Clinical Study to Confirm the Full Antiplatelet Benefit of New Combination Medicine CGT-2168 2Cerimon Pharmaceuticals Initiates Phase II/III Clinical Studies to Evaluate its Diclofenac Patch for Mild to Moderate Pain 2Cerimon Pharmaceuticals Initiates Phase II/III Clinical Studies to Evaluate its Diclofenac Patch for Mild to Moderate Pain 3
(Date:7/31/2015)... Chicago, IL (PRWEB) , ... July 31, 2015 , ... ... which is currently going on in Chicago at Grant Park. The festival ... every corner of North America to Chicago for the annual Lollapalooza. This unique ...
(Date:7/31/2015)... ... July 31, 2015 , ... ... run by GoodThreads. The store can be accessed by visiting http://www.curemeso.org/store . ... which are customizable. The best part: whenever a product is purchased, the Meso ...
(Date:7/31/2015)... ... July 31, 2015 , ... There’s no better way to enjoy ... comes time to cook the next meal, making July the most appropriate to be ... grilling tips and recipes. , Make the next cookout different than the ones in ...
(Date:7/31/2015)... ... , ... Coco Libre announced today that their flagship Organic Coconut Water will ... US Open of Surfing, July 25 through August 2 in Huntington Beach, California. Coco ... market, is a natural choice given the Open’s commitment to sustainable practices. , ...
(Date:7/31/2015)... ... 31, 2015 , ... According to the article published July 27 on My News ... contained and extinguished by the city’s fire department before it caused major damage throughout the ... of the fire, and it was a fire alarm system that tipped off fire fighters ...
Breaking Medicine News(10 mins):Health News:Cheap 2015 Lollapalooza Tickets: Ticket Down Slashes Ticket Prices on Lollapalooza Tickets at Grant Park in Chicago for Saturday, August 1st and Sunday, August 2nd 2Health News:Mesothelioma Organization Launches New Store 2Health News:Mesothelioma Organization Launches New Store 3Health News:King Kullen Honors National Hot Dog and Blueberry Month 2Health News:King Kullen Honors National Hot Dog and Blueberry Month 3Health News:Coco Libre Brings Eco-conscious Hydration to Vans US Open of Surfing 2Health News:Article on Recent Pasadena Courtroom Fire Highlights the Effectiveness of Fire Alarm Systems, Says Fire Protection Group Inc 2Health News:Article on Recent Pasadena Courtroom Fire Highlights the Effectiveness of Fire Alarm Systems, Says Fire Protection Group Inc 3
... University at Buffalo researcher John Violanti, Ph.D., a ... conduct a study on suicide risk among returning veterans. ... the number of soldiers taking their own lives., Violanti ... how quickly persons associate feelings of self-harm, as a ...
... 6 Masimo Corporation (Nasdaq: MASI ), ... Low-Perfusion pulse oximetry, today announced that its management is ... Annual OC Growth Stock Conference at The Ritz-Carlton, Laguna ... 2009, at 11:00 a.m. PT. A live audiocast of ...
... 6 Optimal Reading Services Group, Inc., ... and radiology group practices, announced that its chief executive ... Global Healthcare Services Conference on Monday, February 9, 2009 ... in New York City.Optimal leverages a deep pool of ...
... Study finds great inactivity and little encouragement for kids ... -- Even when they,re playing outside, children tend not ... says. , In fact, the researchers found that ... 5-year-olds was found to be sedentary at community-based preschool ...
... PA -- For years controversy has surrounded whether electronic ... cut medical errors, and reduce healthcare costs. Now, researchers ... discovered a way to get another bonus from the ... treatments for disease. , In the first ...
... VOLC ), a leader in the development, manufacturing ... coronary and peripheral artery,disease, today announced that it will ... of fiscal 2008 on Tuesday, February 17. , ... call to discuss its financial results,and operating activities open ...
Cached Medicine News:Health News:Masimo to Present at the Roth Capital Partners 21st Annual OC Growth Stock Conference 2Health News:Optimal Readings to Present at 2009 UBS Global Healthcare Services Conference 2Health News:For Preschoolers, Even 'Play' Tends to Be Sedentary 2Health News:Penn study shows how electronic medical records can be used to test drug efficacy 2Health News:Penn study shows how electronic medical records can be used to test drug efficacy 3Health News:Volcano Corporation Schedules Fourth Quarter Conference Call, Webcast 2
... Helmer Platelet Agitators feature ... with non-slip texture coating ... circulation for your platelets. ... to be used in ...
... Helmer platelet agitators offer a wide range ... allow the drawer storage platform to agitate ... which wear down and squeak. Sturdy, one-piece ... uniform air circulation for your platelets., ,i.Series ...
Platelet agitator....
EIA Kit for the detection of progesterone....
Medicine Products: