Navigation Links
Cellzome Announces Second Major Strategic Drug Discovery Alliance with GlaxoSmithKline in Inflammatory Disease
Date:3/10/2010

Var3=s.prop5;s.prop15='87203212';s.tl(this,'o','ExternalLink');" target='_blank' href="http://www.cellzome.com">http://www.cellzome.com.

About Episphere(TM) and epigenetics

Episphere(TM) is a chemical proteomics technology for the discovery of novel drugs directed against targets involved in epigenetic regulation. The technology allows the screening and profiling of inhibitors of epigenetic targets in their native environment, directly in the lysate of cells and tissues and can also differentiate between the complexes these targets operate in. The term epigenetics refers to heritable changes in gene expression and phenotype caused by mechanisms other than changes in DNA sequence. One major mechanism is the specific enzymatic modification of histone tails, which affects the packaging of DNA into chromatin and through that controls the transcription of specific genes. Enzymes, such as histone deacetylases (HDAC) or methyltransferases (HMT) can change the modification of the histone tails and therefore change the 'histone code'. Dysregulation of these modifications is thought to play a central role in cancer and in chronic degenerative diseases like neurological and autoimmune disease. The enzymes which carry out these histone modifications are part of large multifunctional protein complexes, which represent attractive novel targets for drug discovery.


'/>"/>
SOURCE Cellzome
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. InterMune Announces Conference Call and Webcast to Discuss Outcome of FDA Advisory Committee
2. Micromet Announces Proposed Public Offering of Common Stock
3. Orthopaedic Synergy, Inc. Announces Letter of Intent to Acquire Praxim, SA.
4. MiMedx Group Announces Addition of Sales Director for Europe
5. Arbor Pharmaceuticals Announces the Launch of Pediaderm(TM) HC Complete Kit - A Comprehensive Approach to the Management of Atopic Dermatitis
6. Orexigen(R) Therapeutics Announces Fourth Quarter and Year Ended December 31, 2009 Financial Results
7. INSYS Therapeutics, Inc. Announces Positive Phase III Efficacy Trial Results for Fentanyl Sublingual Spray
8. Genomic Health Announces Publication of Study Using Oncotype DX(R) in Node-Negative and Node-Positive Breast Cancer Patients Treated With Aromatase Inhibitors
9. BioSpecifics Technologies Corp. Announces Availability of XIAFLEX(TM) for the Treatment of Dupuytrens Contracture
10. Microfluidics Announces Two New Board Members
11. Lexicon Announces Proposed $95 Million Common Stock Offering
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/3/2015)... India , July 4, 2015 ... continue cible les épidémies que sont l,hypertension, le ... et du Sud-Est, par l,intermédiaire de plateformes éducatives ... maladies.      (Photo: http://photos.prnewswire.com/prnh/20150630/227090 ... en charge le diabète en ligne , ...
(Date:7/3/2015)... MUMBAI , July 3, 2015 /PRNewswire/ ... gab heute bekannt, vorbehaltlich bestimmter Abschlussbedingungen eine ... Russland erworben zu haben. Mit dieser Übernahme ... der mit einem Umsatz von 765 Mrd. ... größten Pharmamärkten der Welt gehörte (IMS Health). ...
(Date:7/2/2015)... CHAPEL HILL, N.C. , July 2, 2015 ... their own employees to capture critical product and ... there are many benefits to employee-based studies, it ... to leverage their own internal employees to capture ... recent study by benchmarking firm, Best Practices, LLC, ...
Breaking Medicine Technology:Lutter contre trois maladies chroniques majeures en Asie centrale et du Sud-Est grâce à la formation médicale 2Lutter contre trois maladies chroniques majeures en Asie centrale et du Sud-Est grâce à la formation médicale 3Lupin übernimmt Biocom aus Russland 2Lupin übernimmt Biocom aus Russland 3Leveraging Employee Insights to Produce Cutting-Edge Market Research 2
... Holdings, Inc. (OTC Bulletin Board: ... discovery, development and commercialization of novel drugs in the ... announced that the company provided testimony at the U.S. ... Human Services (HHS) Hearing on  "Defending Against Public Health ...
... ALEXANDRIA, Va., Oct. 4 The ... new division of the association dedicated to advancing ... (Logo:   http://photos.prnewswire.com/prnh/20100106/DC33253LOGO ) ... is recognized as the advocate for independent community ...
Cached Medicine Technology:Advanced Life Sciences Offers Testimony at Senate Hearing on Defending Against Public Health Threats 2Advanced Life Sciences Offers Testimony at Senate Hearing on Defending Against Public Health Threats 3Advanced Life Sciences Offers Testimony at Senate Hearing on Defending Against Public Health Threats 4NCPA Announces New Division Dedicated to Long-Term Care Pharmacies, Patients 2NCPA Announces New Division Dedicated to Long-Term Care Pharmacies, Patients 3
(Date:7/3/2015)... ... July 03, 2015 , ... Brendon Burchard's new ... buzz of media attention. In an effort to spread the news, a comprehensive ... "These days many people are feeling overwhelmed by stress and fatigue," reports Hendricks. ...
(Date:7/3/2015)... Kan. (PRWEB) , ... July 03, 2015 , ... ... dedicated exclusively to healthcare providers, has been retained to lead a national ... top-ranked executive search firms in the healthcare industry, B. E. Smith has recently ...
(Date:7/3/2015)... ... July 03, 2015 , ... Jennifer Renee Hanes, DO is the ... , the largest network of independent freestanding emergency rooms in the United States. , ... our Sienna Plantation facility,” said Executive Medical Director of First Choice Emergency Room, Dr. ...
(Date:7/3/2015)... ... July 03, 2015 , ... The Celebrity Dresses is currently running a promotion ... of celebrities will have the opportunity to get 10% discount on orders that are ... do not have to use coupon codes or remember redemption codes. , There ...
(Date:7/2/2015)... ... July 02, 2015 , ... ... for her introduction of the Stop Overdose Stat (S.O.S.) Act of 2015 on ... Reed (D-R.I.), this Act seeks to decrease drug overdose – especially of heroin ...
Breaking Medicine News(10 mins):Health News:High Performance Academy - Review Of Brendon Burchard's New High Performance Training Program Released 2Health News:High Performance Academy - Review Of Brendon Burchard's New High Performance Training Program Released 3Health News:Regional Care, Inc. Retains B. E. Smith to Recruit New President 2Health News:Regional Care, Inc. Retains B. E. Smith to Recruit New President 3Health News:Dr. Jennifer Renee Hanes Named by First Choice Emergency Room as Medical Director of Missouri City, TX Facility 2Health News:Dr. Jennifer Renee Hanes Named by First Choice Emergency Room as Medical Director of Missouri City, TX Facility 3Health News:Celebrity Fashion Summer Party Dresses on sale at TheCelebrityDresses.com 2Health News:AAPCC Supports the Stop Overdose Stat Act of 2015 2Health News:AAPCC Supports the Stop Overdose Stat Act of 2015 3
... the psychosocial effects of cleft lip and/or palate among ... predictor of behavioral problems. This study is published in ... ,The study included 160 children and young adults with ... no clefting. Anxiety, self-esteem, depression, behavioral problems, unhappiness with ...
... CRT (cardiac resynchronization therapy) known to be effective in ... death// is also proven for its benefits to diabetic ... the body, is capable of resynchronising the contractions of ... blood is pumped with added efficiency. It is estimated ...
... has led to the development of proposals to dump about 800 ... end of the month. ,The move follows the ... six months should stay on a list. ,Patients ... within six months are referred back to their GP for monitoring. ...
... Disorder (ADHD) cannot sit calmly at one place, pipe ... parents are familiar with the symptoms, the treatment of ... ,The FDA has given instructions that ADHD medication such ... warnings about the possible side effects like heart problems, ...
... spread of a rare HIV-2 virus. // ,Japanese ... against the rare HIV-2 form of the AIDS-causing virus after ... infected. ,An official of the health Ministry, ... question the local health authorities to submit written reports as ...
... be prevented if carbon monoxide is used, according ... paper called "Carbon monoxide inhibits // hypoxia/reoxygenation-induced apoptosis ... published in the September issue of The American ... pregnancy-associated hypertension, affects 5-7% of pregnancies and poses ...
Cached Medicine News:Health News:800 Patients to be Dumped from Hospital Waiting Lists 2Health News:Alternative therapies for ADHD 2Health News:Alternative therapies for ADHD 3Health News:Carbon Monoxide May Prevent Pre-Eclampsia 2
... A fixed pipette is ideal ... single volume. Fixed volume FInnpipettes ... advantages as other Finnpipette Digital ... Super blow-out (1-40ul), Soft-touch tip ...
... The Research Family includes fixed-volume, ... as the electronic Eppendorf Research pro ... button, these compact, high-performance pipettes have ... Optimally suited for use with original ...
... 2000 Pipette is a synonym for pipetting ... robust design, and superior operating comfort. Its ... the measuring stroke and blow-out as well ... system ensures utmost accuracy and precision. Ejection ...
1L...
Medicine Products: