Navigation Links
Cellzome Announces Second Major Strategic Drug Discovery Alliance with GlaxoSmithKline in Inflammatory Disease
Date:3/10/2010

Var3=s.prop5;s.prop15='87203212';s.tl(this,'o','ExternalLink');" target='_blank' href="http://www.cellzome.com">http://www.cellzome.com.

About Episphere(TM) and epigenetics

Episphere(TM) is a chemical proteomics technology for the discovery of novel drugs directed against targets involved in epigenetic regulation. The technology allows the screening and profiling of inhibitors of epigenetic targets in their native environment, directly in the lysate of cells and tissues and can also differentiate between the complexes these targets operate in. The term epigenetics refers to heritable changes in gene expression and phenotype caused by mechanisms other than changes in DNA sequence. One major mechanism is the specific enzymatic modification of histone tails, which affects the packaging of DNA into chromatin and through that controls the transcription of specific genes. Enzymes, such as histone deacetylases (HDAC) or methyltransferases (HMT) can change the modification of the histone tails and therefore change the 'histone code'. Dysregulation of these modifications is thought to play a central role in cancer and in chronic degenerative diseases like neurological and autoimmune disease. The enzymes which carry out these histone modifications are part of large multifunctional protein complexes, which represent attractive novel targets for drug discovery.


'/>"/>
SOURCE Cellzome
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. InterMune Announces Conference Call and Webcast to Discuss Outcome of FDA Advisory Committee
2. Micromet Announces Proposed Public Offering of Common Stock
3. Orthopaedic Synergy, Inc. Announces Letter of Intent to Acquire Praxim, SA.
4. MiMedx Group Announces Addition of Sales Director for Europe
5. Arbor Pharmaceuticals Announces the Launch of Pediaderm(TM) HC Complete Kit - A Comprehensive Approach to the Management of Atopic Dermatitis
6. Orexigen(R) Therapeutics Announces Fourth Quarter and Year Ended December 31, 2009 Financial Results
7. INSYS Therapeutics, Inc. Announces Positive Phase III Efficacy Trial Results for Fentanyl Sublingual Spray
8. Genomic Health Announces Publication of Study Using Oncotype DX(R) in Node-Negative and Node-Positive Breast Cancer Patients Treated With Aromatase Inhibitors
9. BioSpecifics Technologies Corp. Announces Availability of XIAFLEX(TM) for the Treatment of Dupuytrens Contracture
10. Microfluidics Announces Two New Board Members
11. Lexicon Announces Proposed $95 Million Common Stock Offering
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2015)... Shakti, LLC, today announced that it has changed its name ... Logo - http://photos.prnewswire.com/prnh/20150827/261551LOGO ... our transformation into a company focused on patent claim analysis ... validity." In ... the Company commenced a corporate re-branding initiative in order to ...
(Date:8/28/2015)... 2015  Perrigo Company plc ("Perrigo") (NYSE: PRGO ... acquisition of leading OTC brands from GSK in an ... is a clear demonstration of Perrigo,s unique ability to ... network spanning 36 countries.  Perrigo Chairman, ... "We are excited to complete this transaction, which clearly ...
(Date:8/28/2015)... PITTSBURGH , Aug. 28, 2015 ... announced that its shareholders have approved Mylan,s proposed ... ; TASE) and the related issuance of Mylan ... general meeting of shareholders held today. The transaction ... the extraordinary general meeting. In addition, the transaction ...
Breaking Medicine Technology:IP Shakti, LLC Changes Company Name to Prediqtus, LLC 2Perrigo Completes Acquisition of Leading Portfolio of OTC Brands from GSK 2Perrigo Completes Acquisition of Leading Portfolio of OTC Brands from GSK 3Perrigo Completes Acquisition of Leading Portfolio of OTC Brands from GSK 4Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 2Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 3Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 4Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 5Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 6Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 7Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 8Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 9
... Prime Therapeutics, one of the nation,s leading pharmacy ... offering a complete spectrum of options from rich benefits ... comes with a net drug spend guarantee of $47 ... predictable for plan sponsors," said Michael Showalter, Prime Chief ...
... an Informa business unit, and the world,s leading research ... from the 14th International Conference on Alzheimer,s Disease (ICAD ... continues to develop beta amyloid targeting drugs, amyloid targets ... warning for risk of Alzheimer,s. According to ...
Cached Medicine Technology:Prime Therapeutics Announces Pharmacy Offering with Guaranteed Net Spend Per Prescription 2Global Standardization for Alzheimer's Biomarkers Moves a Major Step Closer to Reality 2
(Date:8/28/2015)... ... August 28, 2015 , ... Northridge dentists Dr. Elyson and ... just $199, patients can currently receive a one hour treatment of this teeth whitening ... it includes a number of unique features that can turn teeth up to nine ...
(Date:8/28/2015)... , ... August 28, 2015 , ... ... announce its collaboration with coffee connoisseur and Emmy-nominated actress, Sofia Vergara, and unveil ... features revolutionary Thermal Flavor Extraction™ technology, which delivers a variety of sizes and ...
(Date:8/28/2015)... ... August 28, 2015 , ... ... to distributing health information technology innovation to transform quality and efficiency of healthcare ... survey will be de-identified and aggregated before being publicly shared to document progress ...
(Date:8/28/2015)... DC (PRWEB) , ... August ... ... Information Services, Inc.’s (AIS) Medicare-Medicaid Dual Eligibles Database have added comprehensive information ... CMS-backed alignment demonstration approved for a December 2015 launch; and Idaho’s partnership ...
(Date:8/28/2015)... ... August 28, 2015 , ... Popular review site ... millionaire dating sites . According to the listings, MillionaireMatch.com bags the ... category. , A spokesperson of Top5MillionaireDatingSites.com said, “This website has been ...
Breaking Medicine News(10 mins):Health News:Northridge Dentists Dr. Elyson and Dr. Assili Now Offer a Special Promotion on Zoom Teeth Whitening 2Health News:Sofia Vergara Partners With SharkNinja® To Launch The Ninja Coffee Bar™ 2Health News:Sofia Vergara Partners With SharkNinja® To Launch The Ninja Coffee Bar™ 3Health News:WEDI's The Sullivan Institute for Healthcare Innovation Releases Gaps in Care Survey 2Health News:AIS Duals Database: August Update Finds Two New Duals Programs in Rhode Island and Idaho 2Health News:Top5MillionaireDatingSites.com Publishes Its First List of Reviews of the Best Millionaire Dating Sites 2
... TeamStaff, Inc.,(Nasdaq: TSTF ) a national provider of ... notified by the Nasdaq Stock,Market that the Nasdaq Hearings ... the Nasdaq Global Market pending the effectiveness of the,Company,s ... was held on February 7, 2008. The decision of ...
... mg Delivers the Same, Medicine at the Same Dose ... Nearly 30 Million Frequent ... Beginning early March 2008,the nearly 30 million frequent heartburn ... them as retailers begin selling store,brand Omeprazole, a proton ...
... CHAPEL HILL, N.C., March 12 R&D structure ... is,essential to pharmaceutical companies. In a competitive market ... process increases -- the need to have an,optimized ... Discover the best-suited organizational structure that promotes rapid,growth, ...
... Calif., March 12 Omnicell,Inc. (Nasdaq: OMCL ), ... announced today that it has completed its $40.0,million program ... of,2,133,898 shares were repurchased at an average price of ... OMCL ) is a leading provider of systems and,software ...
... part of its ongoing effort to,give consumers information ... announced that four area hospitals have been,selected as ... Blue Distinction(R) is a nationwide program created ... care decisions and to work with their,health care ...
... Plans Participation in 2009 Medicare Advantage Open Enrollment in ... Florida Upon Approval of Applications, ... (Pink Sheets: PHYH), a developer of,health maintenance organizations (HMOs) in ... applications for the launch,of its pilot HMO in the state ...
Cached Medicine News:Health News:Nasdaq Hearings Panel Grants TeamStaff's Request for Continued Listing Subject to a Reverse Stock Split 2Health News:Nasdaq Hearings Panel Grants TeamStaff's Request for Continued Listing Subject to a Reverse Stock Split 3Health News:First Over-The-Counter Store Brand Omeprazole Offering in U.S. Market Creates New Option for Frequent Heartburn Sufferers 2Health News:First Over-The-Counter Store Brand Omeprazole Offering in U.S. Market Creates New Option for Frequent Heartburn Sufferers 3Health News:R&D Quality Excellence: Proven Tactics Optimize the R&D Quality Organizations of Pharmaceutical and Biotech Industries 2Health News:Omnicell Announces Completion of Its Common Stock Repurchase Plan 2Health News:Independence Blue Cross Announces Blue Distinction Centers for Complex and Rare Cancers(SM) in Philadelphia 2Health News:Independence Blue Cross Announces Blue Distinction Centers for Complex and Rare Cancers(SM) in Philadelphia 3Health News:Phyhealth Submits HMO Applications with Required Federal and State Agencies 2Health News:Phyhealth Submits HMO Applications with Required Federal and State Agencies 3
The Stryker Shoulder Instrumentation Set is ideal for open and arthroscopic shoulder procedures. The kit includes all the necessary tools for bone and tissue preparation as well as suture management ...
... The Arthroscopy Scissor is ideal for excising soft ... debris in the joint. The serrated edge on ... well as hold tissue within the jaws for ... and right jaw curvatures, are the perfect tools ...
... Instrument program offers state-of-the-art quality in an ... strength and durability. Low profile cutting tips ... spaces. Series I instruments are available in ... and angle required for large and small ...
... Series I Instrument program offers state-of-the-art quality ... while maintaining strength and durability. Low profile ... tight joint spaces. Series I instruments are ... style, size and angle required for large ...
Medicine Products: