Navigation Links
Cellular Dynamics International Unlocks the Potential of Banked Blood Samples
Date:6/27/2011

MADISON, Wis., June 27, 2011 /PRNewswire/ -- Cellular Dynamics International (CDI) today announced the online publication of an article in the journal Blood demonstrating for the first time a methodology for researchers to access the biology stored in repositories of banked blood samples through the creation of induced pluripotent stem cells (iPSCs). According to the article, entitled "Human lymphoblastoid B-cell lines reprogrammed to EBV-free induced pluripotent stem cells," the derived iPSCs retained genotypic identity and were differentiated into cell types comprising all three germ layers in the body, including blood, heart, neural, and liver cells.

Blood samples are often banked as reference material from the study of various diseases, rare genetic disorders and genome wide association studies (GWAS). To bank these blood lines, they are genetically modified through the introduction of Epstein-Barr virus (EBV) to enable them to be frozen, thawed and proliferate indefinitely, known as "immortalization." This Blood paper describes the ability to take small volumes of EBV-transformed blood and create induced pluripotent stem cells (iPSCs), as well as terminally differentiated somatic cells, that do not contain the EBV genetic modification.

"CDI's published methodology enables the unprecedented opportunity to take samples from disease cohort repositories worldwide, where blood has been collected and immortalized from patients with a wide variety of diseases and known genotypic and phenotypic backgrounds, and create iPSC-based human cellular models for disease research and drug discovery," said Nick Seay, CDI Chief Technology Officer and an author of the paper.  "Our ability to take samples of banked blood and create EBV-free iPSCs, and use that material to manufacture cells in the quantity, quality and purity required for research, is an important step forward in the study of human biology and understanding the promise of regene
'/>"/>

SOURCE Cellular Dynamics International, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2

Related medicine technology :

1. Largest Acellular Dermal Allografts Available for Abdominal Wall Reconstruction Introduced at AWR 2011
2. iPS Academia Japan, Inc. to Distribute Cellular Dynamics iCell® Products in Japan
3. Cellular Dynamics Raises $30 Million to Expand Its Product Line of Human Stem Cells and Tissue Cells
4. FDA Approves Special Protocol Assessment for Phase 3 Trial of Polaris Groups Cancer Therapeutic, ADI-PEG 20, in the Treatment of Hepatocellular Carcinoma
5. Cellular Dynamics International and Roche Transition Early Access Collaboration into a Standard Supply Agreement Ahead of Schedule
6. Intra-Cellular Therapies and Takeda Enter into Worldwide Collaboration to Develop and Commercialize Compounds for Schizophrenia
7. SecuraTrac Reveals Revolutionary Safety Solution Based on GPS & Cellular Technology at CES 2011
8. Transposagen and Cellular Dynamics International Cross-License Technologies for Induced Pluripotent Stem Cells
9. Largest Acellular Dermal Allografts for Abdominal Wall Repair Now Available From MTF
10. Tengion Presents New Data Demonstrating Functional Regeneration in a Diabetic Chronic Kidney Failure Model at the International Society for Cellular Therapy
11. Intra-Cellular Therapies Announces the Successful Completion of a Phase Ib/II Study of ITI-007 in Patients with Schizophrenia
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/23/2015)... FORT MYERS, Fla. , Jan. 23, 2015  Today ... approval of Novartis, Bexsero® for the prevention of ... to 25. Bexsero and Pfizer,s vaccine Trumenba®, which received ... in helping prevent this devastating disease. ...
(Date:1/23/2015)... to Fight Chronic Disease (PFCD) released a public opinion poll of ... study analyzing the impact of increased cost sharing on patient adherence ... educate policy makers and the public on the costs of chronic ... the Iowa healthcare exchange could be improved ...
(Date:1/23/2015)... than a third of reproductive-aged women enrolled in Medicaid, and ... a prescription for an opioid pain medication each year during ... Mortality Weekly Report (MMWR). Opioids are typically ... pain.  They are also found in some prescription cough medications. ...
Breaking Medicine Technology:The National Meningitis Association (NMA) Applauds FDA Approval of Second Vaccine To Protect Against Serogroup B Meningococcal Disease 2New research shows Iowa health exchange would benefit from improvements 2New research shows Iowa health exchange would benefit from improvements 3Opioid painkillers widely prescribed among reproductive age women 2Opioid painkillers widely prescribed among reproductive age women 3
... NEW YORK, Oct. 25, 2011 Reportlinker.com ... is available in its catalogue: ... http://www.reportlinker.com/p090623/Global-Eyeglasses-Industry.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Ophthalmic_Devices This report ... Million Units and US$ Million by the ...
... SAN DIEGO, Oct. 25, 2011 Aethlon ... developing therapeutic filtration devices to address infectious disease ... A. Joyce will present a company overview, discuss ... medical device partnering conference: Investment-In-Innovation (IN3) SUMMIT on ...
Cached Medicine Technology:Global Eyeglasses Industry 2Global Eyeglasses Industry 3Global Eyeglasses Industry 4Global Eyeglasses Industry 5Global Eyeglasses Industry 6Global Eyeglasses Industry 7Global Eyeglasses Industry 8Global Eyeglasses Industry 9Global Eyeglasses Industry 10Global Eyeglasses Industry 11Global Eyeglasses Industry 12Global Eyeglasses Industry 13Aethlon Medical to Present at IN3 Medical Innovation Summit on October 27th 2
(Date:1/22/2015)... (PRWEB) January 22, 2015 The Incredible Bulk ... Ben Pakulski to increase lean muscle by up to 30lbs ... caught the attention of HealthyandFitZone.com’s Stan Stevenson, prompting an investigative ... it is a step-by-step, scientific diet formula that allows the ...
(Date:1/22/2015)... Florida (PRWEB) January 22, 2015 Juvent ... today at the 2015 PGA Merchandise Show to bestow ... and incredible female amateur golfer, Arlene McKitrick. The award ... female amateur golf tournament win. She won her first ...
(Date:1/22/2015)... Carinsurancesavings.biz has released a new blog post ... insurance . , Purchasing an accidental death and dismemberment ... This type of rider provides benefits if the insured dies ... a lesser form of life insurance. , AD&D is ...
(Date:1/22/2015)... Palm City, Florida (PRWEB) January 22, 2015 ... use cold therapy machine with patented IsoTube design to treat ... has introduced the most progressive and easy to use ... help treat post-operative and sports related orthopedic and muscle injuries. ...
(Date:1/22/2015)... JJsHouse.com is a famous dress online store for wedding dresses ... latest collection of wedding dresses , and launches a site-wide ... wedding dress on your big day; the wedding gown is ... wants to find the most suitable wedding dress. Now, we ...
Breaking Medicine News(10 mins):Health News:The Incredible Bulk: Review Examining Ben Pakulski’s Brand New Bulking Muscle Building Diet Program Released 2Health News:All-Time Leading Female Amateur Golfer Arlene McKitrick Receives Juvent Sports Achievement Award at 2015 PGA Show 2Health News:All-Time Leading Female Amateur Golfer Arlene McKitrick Receives Juvent Sports Achievement Award at 2015 PGA Show 3Health News:Accidental Death and Dismemberment Insurance Can Be Purchased at Low Prices Online 2Health News:IsoComforter Introduces Best of Class Cold Therapy Product to the Worldwide Market 2Health News:Find The Most Suitable Wedding Dress At JJsHouse.com 2
... SANTA ANA, Calif., June 26 Grubb & ... SouthCrest Medical Plaza, a,two- building medical office property ... Located at 1035 and 1045 Southcrest Drive, SouthCrest ... gross leaseable area,situated on approximately 9.7 acres of ...
... Center within the Herbert Irving Comprehensive Cancer Center at ... recruiting patients for a clinical research study of a ... a cancer of the lung,s lining that is almost ... standard treatment for pleural mesothelioma is currently surgery to ...
... 26, 2008)Recombinant human erythropoietin (rHuEpo) is a genetically engineered ... and marathon runners to boost their endurance. The potential ... from athletes. Since the test was introduced in 2000, ... the World Anti-Doping Agency (WADA) to administer the procedure. ...
... only way to flatten the,trajectory of healthcare spending ... last week,s I3 (insight, innovation and impact) Conference,sponsored ... keynote speaker,Wally Gomaa, president of Trajectory Health, effectively ... begin (or continue) working,together to positively impact the ...
... Company Holds Launch Events Throughout Cities in Guangdong and Guangxi ... ... Pa., June 26 /Xinhua-PRNewswire-FirstCall/ -- BMP,Sunstone Corporation (Nasdaq: BJGP; "BMP Sunstone" ... People,s Republic of,China. The Company will market and distribute Ferriprox under ...
... YORK, June 26 Golf pro, Jane Park, 21,of ... Open, is helping to,raise awareness for Parkinson,s disease. She ... J. Fox Foundation to help fund critically needed,Parkinson,s research. ... 26-29, will be her inaugural fundraising event as a ...
Cached Medicine News:Health News:Grubb & Ellis Healthcare REIT Acquires SouthCrest Medical Plaza in Stockbridge, Ga. 2Health News:Grubb & Ellis Healthcare REIT Acquires SouthCrest Medical Plaza in Stockbridge, Ga. 3Health News:New clinical trial for patients with asbestos-associated lung cancer 2Health News:New study examines the validity of epo testing 2Health News:New study examines the validity of epo testing 3Health News:Aegis Health Group Revealed Next Generation of Employer-Based Health-Improvement Strategies at Nashville Conference 2Health News:BMP Sunstone Announces Official Launch of Ferriprox in PRC 2Health News:BMP Sunstone Announces Official Launch of Ferriprox in PRC 3Health News:LPGA Golfer Jane Park to Raise Funds for Michael J. Fox Foundation for Parkinson's Research 2
... VICTOR2 V ... fluorescence polarization, luminescence, ... and absorbance. A ... LANCE assay. All ...
The basic modular version of the VICTOR2 multilabel counter for fluorescence, luminescence and absorption measurements, with the stacker and the robotic loading configuration....
... offering 96-channel parallel detection of fluorescence, absorption ... microtiter plates. Compact workstations and systems ... transport of microtiter plates with a throughput ... need for mechanical switching required by numerous ...
Easy to use , Allow for a flexible washing , Uniform and efficient , Very robust and reliable , Adjustable to all well shapes , Rack included (not autoclavable) , Autoclavable at 121C , No e...
Medicine Products: