Navigation Links
Cellular Dynamics International Unlocks the Potential of Banked Blood Samples
Date:6/27/2011

MADISON, Wis., June 27, 2011 /PRNewswire/ -- Cellular Dynamics International (CDI) today announced the online publication of an article in the journal Blood demonstrating for the first time a methodology for researchers to access the biology stored in repositories of banked blood samples through the creation of induced pluripotent stem cells (iPSCs). According to the article, entitled "Human lymphoblastoid B-cell lines reprogrammed to EBV-free induced pluripotent stem cells," the derived iPSCs retained genotypic identity and were differentiated into cell types comprising all three germ layers in the body, including blood, heart, neural, and liver cells.

Blood samples are often banked as reference material from the study of various diseases, rare genetic disorders and genome wide association studies (GWAS). To bank these blood lines, they are genetically modified through the introduction of Epstein-Barr virus (EBV) to enable them to be frozen, thawed and proliferate indefinitely, known as "immortalization." This Blood paper describes the ability to take small volumes of EBV-transformed blood and create induced pluripotent stem cells (iPSCs), as well as terminally differentiated somatic cells, that do not contain the EBV genetic modification.

"CDI's published methodology enables the unprecedented opportunity to take samples from disease cohort repositories worldwide, where blood has been collected and immortalized from patients with a wide variety of diseases and known genotypic and phenotypic backgrounds, and create iPSC-based human cellular models for disease research and drug discovery," said Nick Seay, CDI Chief Technology Officer and an author of the paper.  "Our ability to take samples of banked blood and create EBV-free iPSCs, and use that material to manufacture cells in the quantity, quality and purity required for research, is an important step forward in the study of human biology and understanding the promise of regene
'/>"/>

SOURCE Cellular Dynamics International, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2

Related medicine technology :

1. Largest Acellular Dermal Allografts Available for Abdominal Wall Reconstruction Introduced at AWR 2011
2. iPS Academia Japan, Inc. to Distribute Cellular Dynamics iCell® Products in Japan
3. Cellular Dynamics Raises $30 Million to Expand Its Product Line of Human Stem Cells and Tissue Cells
4. FDA Approves Special Protocol Assessment for Phase 3 Trial of Polaris Groups Cancer Therapeutic, ADI-PEG 20, in the Treatment of Hepatocellular Carcinoma
5. Cellular Dynamics International and Roche Transition Early Access Collaboration into a Standard Supply Agreement Ahead of Schedule
6. Intra-Cellular Therapies and Takeda Enter into Worldwide Collaboration to Develop and Commercialize Compounds for Schizophrenia
7. SecuraTrac Reveals Revolutionary Safety Solution Based on GPS & Cellular Technology at CES 2011
8. Transposagen and Cellular Dynamics International Cross-License Technologies for Induced Pluripotent Stem Cells
9. Largest Acellular Dermal Allografts for Abdominal Wall Repair Now Available From MTF
10. Tengion Presents New Data Demonstrating Functional Regeneration in a Diabetic Chronic Kidney Failure Model at the International Society for Cellular Therapy
11. Intra-Cellular Therapies Announces the Successful Completion of a Phase Ib/II Study of ITI-007 in Patients with Schizophrenia
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/31/2015)... -- Galmed Pharmaceuticals Ltd. (Nasdaq: GLMD ) ("Galmed"), ... and commercialization of a once-daily, oral therapy for ... today announced financial results for the 12 months ... 2014 Highlights: , Hosted a key opinion ... Rohit Loomba, MD, MHSc., who discussed the topic ...
(Date:3/31/2015)... , March 31, 2015  CVS Health (NYSE: ... into new clinical affiliations with Rush University Medical ... and Tucson Medical Center in Tucson, ... Arizona Connected Care. These affiliations will help enhance ... patients. Through these clinical affiliations, CVS Health will ...
(Date:3/31/2015)... , March 31, 2015  Oxis International, Inc. (OXIS) ... development and commercialization, announced today Oxis CEO Tony ... of Oxis common shares on the Euronext exchange. Oxis ... the symbol OXIS.   Oxis Chairman and ... to move forward with its strategies launched in 2014 ...
Breaking Medicine Technology:Galmed Pharmaceuticals Reports Full Year 2014 Financial Results and Provides Business Update 2Galmed Pharmaceuticals Reports Full Year 2014 Financial Results and Provides Business Update 3Galmed Pharmaceuticals Reports Full Year 2014 Financial Results and Provides Business Update 4Galmed Pharmaceuticals Reports Full Year 2014 Financial Results and Provides Business Update 5Galmed Pharmaceuticals Reports Full Year 2014 Financial Results and Provides Business Update 6Galmed Pharmaceuticals Reports Full Year 2014 Financial Results and Provides Business Update 7Galmed Pharmaceuticals Reports Full Year 2014 Financial Results and Provides Business Update 8CVS Health Announces New Clinical Affiliations with Leading Medical Centers in Arizona and Illinois 2CVS Health Announces New Clinical Affiliations with Leading Medical Centers in Arizona and Illinois 3Oxis International Inc. Announces Request for Euronext Trading Suspension 2
... Mich., and GERMANTOWN, Md., Nov. 21, 2011 Adeona ... a developer of innovative disease-modifying medicines for serious ... Corporation, a synthetic biology company that utilizes its ... announced today the formation of a global exclusive ...
... 18, 2011 Breast cancer patients, their families and ... Administration (FDA) decision to remove the anti-cancer drug Avastin ... stage breast cancer. Terry Kalley, founder of ... condemned the decision, saying, "While this vote is highly ...
Cached Medicine Technology:Adeona Pharmaceuticals and Intrexon Announce Worldwide Exclusive Collaboration for Synthetic DNA-based Therapy for Pulmonary Arterial Hypertension 2Adeona Pharmaceuticals and Intrexon Announce Worldwide Exclusive Collaboration for Synthetic DNA-based Therapy for Pulmonary Arterial Hypertension 3Adeona Pharmaceuticals and Intrexon Announce Worldwide Exclusive Collaboration for Synthetic DNA-based Therapy for Pulmonary Arterial Hypertension 4Adeona Pharmaceuticals and Intrexon Announce Worldwide Exclusive Collaboration for Synthetic DNA-based Therapy for Pulmonary Arterial Hypertension 5Adeona Pharmaceuticals and Intrexon Announce Worldwide Exclusive Collaboration for Synthetic DNA-based Therapy for Pulmonary Arterial Hypertension 6Adeona Pharmaceuticals and Intrexon Announce Worldwide Exclusive Collaboration for Synthetic DNA-based Therapy for Pulmonary Arterial Hypertension 7
(Date:3/31/2015)... NJ (PRWEB) March 31, 2015 Dr. Russell ... for Advanced Reconstruction. He was recently quoted in an ... caused by lymphatic issues, causing fluid retention and tissue swelling. ... procedure to relieve and / or improve lymphedema symptoms. ... improve or alleviate the symptoms of lymphedema. The goal ...
(Date:3/31/2015)... Dr. Uzma Parvez is having a busy start to ... Grounds Presentations at St. Michael’s Medical Center for attending staff ... The event was attended by a large gathering of students, ... from the Grand Rounds. It was said that it ... while. , Ahead, Dr. Parvez has been invited to ...
(Date:3/31/2015)... TX (PRWEB) March 31, 2015 One of the ... be a visit to Mount Kilauea on the big island. ... few places where you can see molten lava slowly oozing at ... on earth. , One place you would never expect ... the flat, arid terrain of Mission, Texas -- until now. , ...
(Date:3/31/2015)... March 31, 2015 BESLER Consulting ... entitled, “The Value of an Independent Cost Report ... play a critical role in the determination of ... the appropriate understanding and review, this report can ... strategic planning. , This white paper discusses:, ...
(Date:3/31/2015)... WA (PRWEB) March 31, 2015 ... insurance exchange technology, has announced that Lance Hood, Senior ... HealthCare Consumerism Private Exchange Forum on April 1, 2015. ... Development of Benaissance, will address how employers can streamline ... process. , WHAT: “ Optimizing Employee and Employer ...
Breaking Medicine News(10 mins):Health News:The Physicians at Plastic Surgery Center Each Have Something to Celebrate This March 2Health News:The Physicians at Plastic Surgery Center Each Have Something to Celebrate This March 3Health News:The Physicians at Plastic Surgery Center Each Have Something to Celebrate This March 4Health News:NJ Top Docs Presents, Dr. Uzma Parvez of Total Pain Care 2Health News:Rare Volcano Constructed inside Gold’s Gym in Mission, Texas 2Health News:Rare Volcano Constructed inside Gold’s Gym in Mission, Texas 3Health News:Array Health’s Senior Director of Marketing to Co-Present with Benaissance at The Institute for HealthCare Consumerism Private Exchange Forum 2
... Doheny HealthDay Reporter , THURSDAY, June 24 ... to reduce the risk of invasive breast cancer by ... a woman is considering bisphosphonate use for bone, this ... Chlebowski, a clinical oncologist at the Los Angeles Biomedical ...
... , THURSDAY, June 24 (HealthDay News) -- Ninety percent of ... government report reveals. In fact, salt is so pervasive ... consume less. Too much salt can increase your blood pressure, ... "Nine in 10 American adults consume more salt than ...
... readily and safely distinguished the brains of Alzheimer,s disease ... the doors to making such imaging available beyond facilities ... reported by a Johns Hopkins team in the June ... better ways to distinguish Alzheimer,s from other types of ...
... at Erasmus MC University Medical Centre in The Netherlands ... for the development of de novo cancer in liver ... of Liver Transplantation , a journal published by ... Study of Liver Diseases (AASLD). The 1-year survival ...
... Previous studies have shown that antiviral treatment reduces the ... hepatitis B (CHB). But now, researchers from the Division ... reporting that the antiviral therapy also prevents recurrence of ... of care for patients with HCC is local ablation ...
... NEW YORK (June 24, 2010) A team of ... developed a method to predict post-stroke recovery of language ... to predict recovery has important implications for stroke survivors ... long-term treatment needs. Findings are reported online in the ...
Cached Medicine News:Health News:Bone-Building Pills Appear to Lower Invasive Breast Cancer Risk 2Health News:Bone-Building Pills Appear to Lower Invasive Breast Cancer Risk 3Health News:Most Americans Get Too Much Salt 2Health News:Most Americans Get Too Much Salt 3Health News:Novel radiotracer shines new light on the brains of Alzheimer's disease patients 2Health News:Higher cancer rates found in liver transplant patients receiving cyclosporine for immunosuppression 2Health News:Higher cancer rates found in liver transplant patients receiving cyclosporine for immunosuppression 3Health News:Silencing hepatitis B virus prevent recurrence of liver cancer 2Health News:New metric predicts language recovery following stroke 2
Inquire...
... the elegant and sophisticated woman, ... includes ophthalmic and sunwear styles. ... variety of shapes and colors, ... shapes and complexions. Many styles ...
... updated styling through the use of innovative ... collection is for the value driven consumer ... Eyewear Collection , The futuristic quality ... of the "strongest and lightest metal on ...
Inquire...
Medicine Products: