Navigation Links
BioMosaics' Glypican-3 Blood & Tissue Tests Receive CE Marking in Europe
Date:9/10/2007

BURLINGTON, Vt., Sept. 10 /PRNewswire/ -- BioMosaics Inc., a cancer biomarker development company, announced today that it has received CE marking for its proprietary products for the identification of Glypican-3 (GPC3) in human blood and in tissue as in vitro diagnostic tests. This will allow the GPC3 (Human Glypican-3) ELISA Kit for detecting GPC3 in human serum or plasma, and the GPC3 (Human Glypican-3) Monoclonal Antibody (clone 1G12) to detect GPC3 in tissue by immunohistochemistry (IHC), to be marketed in the European Union.

GPC3, an oncofetal antigen, is a member of the glypican family of glycosyl phosphatidylinositol-anchored cell-surface heparan sulfate proteoglycans. The anti-GPC3 monoclonal antibody (MAb; clone 1G12) has also been used to assess GPC3 expression in malignant and non-malignant liver tissue samples and for ELISA detection of GPC3 in the serum. Capurro et al. have shown that GPC3 is expressed at the protein level by immunohistochemistry in most cases of primary liver cancer including small tumors, but is undetectable in normal liver and benign hepatic lesions [Gastroenterology. 2003; 125:89-97]. Three recent major studies using BioMosaics GPC3 MAb have confirmed the early presence of GPC3 on hepatocellular carcinoma (HCC) and highly dysplastic cirrhotic nodules. [Wang XY et al, Human Pathology. 2006; 37(11):1435-41, Libbrecht et al, Am J Surg Pathol. 2006. 30(11):1405-1411, and Di Tommaso, Hepatology. 2007; 45(3):725-34].

Primary Liver Cancer, or Hepatocellular Carcinoma, is one of the most common and aggressive malignant tumors worldwide, causing an estimated one million deaths annually. Over 430,000 new cases of HCC are diagnosed each year. The main causative agents are hepatitis B virus (HBV), hepatitis C virus (HCV), as well as alcoholic cirrhosis and non-alcoholic steatohepatitis (NASH) which is associated with obesity, diabetes, and insulin resistance factors. The incidence of HCC has been steadily increasing over the
'/>"/>

SOURCE BioMosaics Inc.
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2

Related medicine technology :

1. Rapid Whole Blood Testing for Infectious Mononucleosis Antibodies
2. Blood Gas Analysis: The Pros and Cons of Point-Of-Care Testing
3. A 4-Week Therapy with Transition Therapeutics E1-I.N.T. Leads to Sustained Reductions in Blood Glucose Levels for 6 Months Post-treatment in Type 2 Diabetes Patients
4. Bio-Matrix Scientifics Dr. ONeill Sees University of Pittsburghs Published Study on Culture Blood-Forming Stem Cells from Human Fat Tissue as Supporting Near Term Benefits of Banking Adipose (Fat) Derived Stem Cells
5. New Data from Multiple Studies Show Galvus Delivers Consistent and Robust Blood Sugar Control in Patients with Type 2 Diabetes
6. Hypertension Vaccine CYT006-AngQb Achieves Strong Blood Pressure Reduction During Important Early Morning Period When Most Adverse Cardiovascular Events Occur
7. Prexige Study Shows Significantly Less Impact on Blood Pressure Than Ibuprofen in Osteoarthritis Patients with Controlled Hypertension
8. Lumiracoxib Study Showed Significantly Less Impact on Blood Pressure Than Ibuprofen in Osteoarthritis Patients with Controlled Hypertension
9. Algeta Demonstrates Targeted Cancer-killing Potential of Novel Alpha Particle Linked Antibodies in Leading Medical Journal Blood
10. NCI Researchers Discover Genes That Are Turned on at High Levels in Tumor-associated Blood Vessels of Mice and Humans
11. Blood Levels of Paliperidone Extended-Release Tablets are Not Increased by Common Antidepressant
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/23/2014)... July 23, 2014 Pharmavite LLC announced that ... customer officer effective immediately. Toll recently served as Pharmavite,s ... marketing, category management, private label and sales administration in ... new global role, Toll will expand his responsibilities to ... "Toll,s appointment to chief customer officer is ...
(Date:7/23/2014)... 23, 2014  RT Oncology Services Corporation today announced ... its board of directors. Mr. Mundie is currently senior ... works on strategic projects within the company and on ... research and strategy officer. Mike ... said, "Craig is a visionary technology executive. His appointment ...
(Date:7/23/2014)... , July 23, 2014 /PRNewswire-iReach/ -- Top Staten ... Pediatrics offers his feedback on article, which discusses tips for ... http://photos.prnewswire.com/prnh/20140722/129440 According to US ... injury and death among American children aged 1 to 4, ... water." One expert in the article says that ...
Breaking Medicine Technology:Craig Mundie Joins RainTree Oncology Board of Directors 2Craig Mundie Joins RainTree Oncology Board of Directors 3Premier Staten Island Pediatrician Dr. Michael Gabriel Comments On Article Discussing Pool Safety Tips for Parents 2
(Date:7/24/2014)... 24, 2014 Representatives from the internationally ... hand to provide educational and support resources at the ... week in Colorado Springs. , The Annual Meeting brings ... most renowned neurointerventional research centers in the ... together (with or at) symposiums, physician meetings, exhibit hall ...
(Date:7/24/2014)... The Arm Lift, also known as brachioplasty, is a surgical ... upper arms to create a more toned, slimmed appearance. With ... lax and may begin to sag, resulting in loose and ... sagging upper arms, and seek treatment to restore their slimmer, ... offering brachioplasty to tighten and improve the contours of the ...
(Date:7/24/2014)... 24, 2014 American Sentinel University’s ... and Prevent the Three Infections That Make Up ... a go-to guide to help nurses minimize the ... details basic prevention measures that every nurse should ... available for download at http://www.americansentinel.edu/blog/2014/05/13/strong-nursing-leadership-is-essential-to-reducing-hais/ . , ...
(Date:7/24/2014)... CA (PRWEB) July 24, 2014 The Republic ... unveil a new CARDAMOM CRÈME BRÛLÉE TEA to celebrate “The ... Spielberg, Oprah Winfrey and Juliet Blake. A hundred-foot journey begins ... and cross over into a new realm that is far ... however small in physical distance that materially changes the course ...
(Date:7/24/2014)... 24, 2014 Info Cash 2, the latest ... Carpenter that is designed to help the average person learn ... caught the attention of Shane Michaels, prompting an investigative review. ... , “Most everyone you talk to knows that it’s possible ... take the plunge to actually start doing it because for ...
Breaking Medicine News(10 mins):Health News:Brain Aneurysm Foundation Provides Key Support to NeuroIntervential Physicians 2Health News:How to Get Toned Arms With Arm Lift Procedure 2Health News:How to Get Toned Arms With Arm Lift Procedure 3Health News:New E-book Helps Nurses Identify and Prevent Three Most Common Healthcare Associated Infections 2Health News:New E-book Helps Nurses Identify and Prevent Three Most Common Healthcare Associated Infections 3Health News:The Republic of Tea Unveils New Tea Inspired by “The Hundred-Foot Journey” 2Health News:The Republic of Tea Unveils New Tea Inspired by “The Hundred-Foot Journey” 3Health News:Top Info Cash 2.0: Review Examines Chris Carpenter’s New and Updated Video Training Course 2
... released on Wednesday by the Australian National Audit Office ... allowed more than 100,000 people with tuberculosis to ... whether they sought medical treatment, The Australian reports. ... history of the disease sometimes are permitted to enter ...
... up more money to get things right. Some do move the ... news that a hospital group in central Pennsylvania is offering warranty ... of follow-up treatment. ,Even if a patient suffers complications ... to send the insurer another bill. ,Well the ...
... of Psychiatric and Mental Health Nursing in a recent report, ... health support to the victims of the 2005 Bali ... first explosions in 2002. ,Staff at the Royal ... recipients of vital personal support from mental health nurses. ...
... the people who are affected by chronic back pain ... herniated discs , spinal stenosis, and complications from failed ... treating chronic back pain is considered unsuitable due to ... a new study led by Dr. David Abejn investigates ...
... Kalam Thursday stressed on the necessity of extensive stem ... activities of mentally challenged people. ,Addressing ... a premier rehabilitation and research institute for the handicapped, ... and it will take five to 10 years to ...
... both autism and attention deficit hyperactivity (ADHD) are four times ... population. ,However, researchers are cautioning against labelling kids ... they may only be trying to let out pent up ... that needs to be properly channeled, or they may have ...
Cached Medicine News:Health News:US Hospital Group Offers Warranty on Surgeries 2Health News:US Hospital Group Offers Warranty on Surgeries 3Health News:Bali Bombings Helped Improve Trauma Care 2Health News:Bali Bombings Helped Improve Trauma Care 3Health News:Kids With Both Autism and ADHD Four Times More Likely to Bully 2
... The F 255 is a portable, ... relative mV and temperature measurements. Temperature compensated ... with a temperature probe (ATC) or a ... two- and three-point calibration with Auto-Find automatic ...
... Over-sized compressor. Triple pane thermal glass. ... System No plumbing required. Equipped with a ... on Parts & Labor and an Additional 4 ... as a chromatography unit which includes two access ...
... Over-sized compressor. Triple pane thermal glass. ... Self-Contained System No plumbing required. Equipped with ... Warranty on Parts & Labor and an Additional ... available as a chromatography unit which includes two ...
Inquire...
Medicine Products: