Navigation Links
BioMosaics' Glypican-3 Blood & Tissue Tests Receive CE Marking in Europe
Date:9/10/2007

BURLINGTON, Vt., Sept. 10 /PRNewswire/ -- BioMosaics Inc., a cancer biomarker development company, announced today that it has received CE marking for its proprietary products for the identification of Glypican-3 (GPC3) in human blood and in tissue as in vitro diagnostic tests. This will allow the GPC3 (Human Glypican-3) ELISA Kit for detecting GPC3 in human serum or plasma, and the GPC3 (Human Glypican-3) Monoclonal Antibody (clone 1G12) to detect GPC3 in tissue by immunohistochemistry (IHC), to be marketed in the European Union.

GPC3, an oncofetal antigen, is a member of the glypican family of glycosyl phosphatidylinositol-anchored cell-surface heparan sulfate proteoglycans. The anti-GPC3 monoclonal antibody (MAb; clone 1G12) has also been used to assess GPC3 expression in malignant and non-malignant liver tissue samples and for ELISA detection of GPC3 in the serum. Capurro et al. have shown that GPC3 is expressed at the protein level by immunohistochemistry in most cases of primary liver cancer including small tumors, but is undetectable in normal liver and benign hepatic lesions [Gastroenterology. 2003; 125:89-97]. Three recent major studies using BioMosaics GPC3 MAb have confirmed the early presence of GPC3 on hepatocellular carcinoma (HCC) and highly dysplastic cirrhotic nodules. [Wang XY et al, Human Pathology. 2006; 37(11):1435-41, Libbrecht et al, Am J Surg Pathol. 2006. 30(11):1405-1411, and Di Tommaso, Hepatology. 2007; 45(3):725-34].

Primary Liver Cancer, or Hepatocellular Carcinoma, is one of the most common and aggressive malignant tumors worldwide, causing an estimated one million deaths annually. Over 430,000 new cases of HCC are diagnosed each year. The main causative agents are hepatitis B virus (HBV), hepatitis C virus (HCV), as well as alcoholic cirrhosis and non-alcoholic steatohepatitis (NASH) which is associated with obesity, diabetes, and insulin resistance factors. The incidence of HCC has been steadily increasing over the
'/>"/>

SOURCE BioMosaics Inc.
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2

Related medicine technology :

1. Rapid Whole Blood Testing for Infectious Mononucleosis Antibodies
2. Blood Gas Analysis: The Pros and Cons of Point-Of-Care Testing
3. A 4-Week Therapy with Transition Therapeutics E1-I.N.T. Leads to Sustained Reductions in Blood Glucose Levels for 6 Months Post-treatment in Type 2 Diabetes Patients
4. Bio-Matrix Scientifics Dr. ONeill Sees University of Pittsburghs Published Study on Culture Blood-Forming Stem Cells from Human Fat Tissue as Supporting Near Term Benefits of Banking Adipose (Fat) Derived Stem Cells
5. New Data from Multiple Studies Show Galvus Delivers Consistent and Robust Blood Sugar Control in Patients with Type 2 Diabetes
6. Hypertension Vaccine CYT006-AngQb Achieves Strong Blood Pressure Reduction During Important Early Morning Period When Most Adverse Cardiovascular Events Occur
7. Prexige Study Shows Significantly Less Impact on Blood Pressure Than Ibuprofen in Osteoarthritis Patients with Controlled Hypertension
8. Lumiracoxib Study Showed Significantly Less Impact on Blood Pressure Than Ibuprofen in Osteoarthritis Patients with Controlled Hypertension
9. Algeta Demonstrates Targeted Cancer-killing Potential of Novel Alpha Particle Linked Antibodies in Leading Medical Journal Blood
10. NCI Researchers Discover Genes That Are Turned on at High Levels in Tumor-associated Blood Vessels of Mice and Humans
11. Blood Levels of Paliperidone Extended-Release Tablets are Not Increased by Common Antidepressant
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/31/2014)... , October 31, 2014 ... Corporation (NASDAQ: CELG ), Bristol-Myers Squibb Co. ... UNH ), Sanofi SA (NYSE: ... members receive these notes ahead of publication. To reserve ... . , ,-- ,Celgene Corporation Research Reports ,On October ...
(Date:10/31/2014)... , November 3, 2014 ... men with BPH to discuss "male orgasmic dysfunction" with ... ability to treat prostate symptoms while preserving sexual function ... welcomes the publication of a paper in the British ... from enlarged prostate to discuss with their doctors the ...
(Date:10/31/2014)... , Oct. 30, 2014 Migranade, Inc. announced ... be available to the 36 million U.S. migraine sufferers ... technology that targets the actual cause of migraines and ... pain and not the source Migranade is assured to ... MIGRANADE Migraine Relief is available at http://www.migranade.com ...
Breaking Medicine Technology:Financial Results, Acquisition Agreement, and Legal Issue Update - Research Reports on Celgene, Bristol-Myers, UnitedHealth, Sanofi and Actavis 2Financial Results, Acquisition Agreement, and Legal Issue Update - Research Reports on Celgene, Bristol-Myers, UnitedHealth, Sanofi and Actavis 3Financial Results, Acquisition Agreement, and Legal Issue Update - Research Reports on Celgene, Bristol-Myers, UnitedHealth, Sanofi and Actavis 4Financial Results, Acquisition Agreement, and Legal Issue Update - Research Reports on Celgene, Bristol-Myers, UnitedHealth, Sanofi and Actavis 5Financial Results, Acquisition Agreement, and Legal Issue Update - Research Reports on Celgene, Bristol-Myers, UnitedHealth, Sanofi and Actavis 6Sexual Dysfunction No Longer Inevitable When Treating Enlarged Prostate 2Game Changing Migraine Medication To Be Available November 2014 2
... MYSTIC, Conn., Aug. 17 Amarin Corporation plc (Nasdaq: ... a focus on cardiovascular disease, today announced that Colin ... (CEO) and a member of the Company,s Board of ... responsible for driving forward the Company,s strategy to maximize ...
... - Cumberland Pharmaceuticals Inc. (Nasdaq: CPIX ... care and gastroenterology markets, today announces financial results for the ... for full year 2010. Net Revenue:   ... was $10.7 million, up 9% from $9.8 million for the ...
Cached Medicine Technology:Amarin Corporation Appoints Colin W. Stewart as President and Chief Executive Officer 2Amarin Corporation Appoints Colin W. Stewart as President and Chief Executive Officer 3Amarin Corporation Appoints Colin W. Stewart as President and Chief Executive Officer 4Cumberland Pharmaceuticals Reports Second Quarter 2010 Financial Results 2Cumberland Pharmaceuticals Reports Second Quarter 2010 Financial Results 3Cumberland Pharmaceuticals Reports Second Quarter 2010 Financial Results 4Cumberland Pharmaceuticals Reports Second Quarter 2010 Financial Results 5Cumberland Pharmaceuticals Reports Second Quarter 2010 Financial Results 6Cumberland Pharmaceuticals Reports Second Quarter 2010 Financial Results 7Cumberland Pharmaceuticals Reports Second Quarter 2010 Financial Results 8Cumberland Pharmaceuticals Reports Second Quarter 2010 Financial Results 9Cumberland Pharmaceuticals Reports Second Quarter 2010 Financial Results 10Cumberland Pharmaceuticals Reports Second Quarter 2010 Financial Results 11Cumberland Pharmaceuticals Reports Second Quarter 2010 Financial Results 12Cumberland Pharmaceuticals Reports Second Quarter 2010 Financial Results 13
(Date:10/31/2014)... 31, 2014 Springboard Biodiesel, a ... small scale BioPro™ biodiesel processors, announced on Thursday ... improve the performance and efficiency of small-scale biodiesel ... trio will recover more than 99% of ... the glycerin by-product produced while making biodiesel. ...
(Date:10/31/2014)... The Memory Healer review published by DailyGossip.org reveals that the ... from Alzheimer's disease. , In fact, Alexander Lynch has ... His father pointed a gun and shot him during an ... of this method understood that he needed to do something ... is based on years of research. The author of the ...
(Date:10/31/2014)... At the start of 2014, numerous news ... monoxide poisoning in their homes. Now, as 2015 (and ... Missouri-based heating and cooling company is taking a more ... the home heating season with the assurance that their ... Nov. 1, 2014, E and Q Heating and Cooling ...
(Date:10/31/2014)... FRIDAY, Oct. 31, 2014 (HealthDay News) -- Surgery for ... on where in the United States you live, a ... will experience low back pain at some point in ... receive professional medical care for a spine problem," co-author ... & Clinical Practice, said in a college news release. ...
(Date:10/31/2014)... research suggests that insomnia is a major contributor to ... fatal injuries. The results underscore the importance of the ... Sleep Awareness Project. , Results show that the risk ... with the number of insomnia symptoms present. People with ... likely to die from a fatal injury than those ...
Breaking Medicine News(10 mins):Health News:Springboard Biodiesel Announces Release of New and Unique Methanol Recovery and Glycerin Treatment Equipment 2Health News:Springboard Biodiesel Announces Release of New and Unique Methanol Recovery and Glycerin Treatment Equipment 3Health News:"Memory Healer" Review Reveals a New Natural Remedy Guide for Managing Memory Loss 2Health News:Many Homeowners Missing Key Safety Risks with Home Heating;Missouri-based Company E and Q Announces New Safety Check 2Health News:Many Homeowners Missing Key Safety Risks with Home Heating;Missouri-based Company E and Q Announces New Safety Check 3Health News:Spinal Surgery Varies by Region in U.S.: Study 2Health News:Insomnia increases risk of motor vehicle deaths, other fatal injuries 2
... Crdentia Corp. (OTC Bulletin,Board: CRDT), a leading U.S. ... has been awarded an exclusive healthcare staffing,contract by ... Rock Raceway,is a new development project that includes ... single-family lots. High Rock Raceway has partnered ...
... the Campaign to Eliminate Drunk Driving, ST. LOUIS, ... -- a holiday that traditionally brings large numbers of ... supporters have,convened in St. Louis to kick off their ... and Suites Hotel 800 Washington Ave, St.,Louis, Mo. The ...
... reveals racial disparities, troublesome drug side effects , , THURSDAY, ... first annual Breast Cancer Symposium shed light on racial ... can affect survival, and how nagging side effects cause ... in San Francisco, is co-sponsored by the American Society ...
... First-year Results of Guiding Stars, ... System, SCARBOROUGH, Maine, Sept. 6 Consumer,selection of ... outpacing,selection of those that don,t in many aisles of ... faster -- according to data in the year,since the ...
... MYL ) today announced that Mylan Pharmaceuticals Inc. has ... for its,Abbreviated New Drug Application (ANDA) for Carvedilol Tablets, ... Carvedilol Tablets are the generic version of GlaxoSmithKline,s,Coreg(R) Tablets. ... the 12 months ending June 30, 2007, for the ...
... Sept. 5 Fairbank Farms, a national,ground beef ... Ground Round Beef Patties. The ground beef patties, ... purchased by consumers in New,England on Wednesday September ... an abundance of caution, the product has been ...
Cached Medicine News:Health News:Crdentia Selected by High Rock Raceway to Provide Healthcare Staffing Services 2Health News:Hundreds of MADD Supporters Meet in St. Louis on Sept. 6-8 2Health News:Hundreds of MADD Supporters Meet in St. Louis on Sept. 6-8 3Health News:Hundreds of MADD Supporters Meet in St. Louis on Sept. 6-8 4Health News:Hundreds of MADD Supporters Meet in St. Louis on Sept. 6-8 5Health News:Hundreds of MADD Supporters Meet in St. Louis on Sept. 6-8 6Health News:Studies Shed New Light on Breast Cancer, Treatment 2Health News:Studies Shed New Light on Breast Cancer, Treatment 3Health News:Grocery Shoppers Are Following Stars to More Nutritious Choices 2Health News:Grocery Shoppers Are Following Stars to More Nutritious Choices 3Health News:Grocery Shoppers Are Following Stars to More Nutritious Choices 4
...
...
...
EDM Lumbar Drainage Kit with and without Bioglide are fabricated of radiopaque (barium impregnated) silicone tubing, and are packaged with stainless steel stylets inserted in the lumen....
Medicine Products: