Navigation Links
Amylin to Present Data Showing Investigational Metreleptin Treatment Led to Long-Term Improvements in Diabetes and Lipid Control in Patients with Lipodystrophy
Date:4/15/2011

SAN DIEGO, April 15, 2011 /PRNewswire/ -- Amylin Pharmaceuticals, Inc. (Nasdaq: AMLN) today announced results from a new analysis of an ongoing, long-term research study of the investigational drug metreleptin, an analog of the human hormone leptin, for the treatment of lipodystrophy. The study is being conducted by investigators from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) at the National Institutes of Health (NIH). Results from the analysis will be presented by Christian Weyer, M.D., senior vice president, research and development, Amylin Pharmaceuticals, at a late-breaking oral session on Sunday, April 17 at 7:55 a.m. PT at the 20th Annual Meeting and Clinical Congress of the American Association of Clinical Endocrinologists (AACE) in San Diego.

In the study, which has been ongoing for more than 10 years, researchers at the NIH are examining the effect of metreleptin on several metabolic abnormalities, including diabetes and hypertriglyceridemia (high levels of triglycerides in the bloodstream), in patients with rare inherited or acquired forms of lipodystrophy. Treatment with metreleptin resulted in robust reductions from baseline in both A1C and triglycerides. (A1C is a measure of average blood sugar over three months; triglycerides are the major form of fat stored in the body.) These improvements were apparent at four months and generally sustained for up to several years of treatment.

"Patients with rare forms of lipodystrophy are often affected by the disease early in life, are at high risk of acute and chronic complications and, currently, have very limited therapeutic options," said Dr. Weyer. "The results of our analysis reaffirm the potential of metreleptin as an important advance for people living with this chronic and often debilitating metabolic disease. We continue to work diligently toward bringing this potential
'/>"/>

SOURCE Amylin Pharmaceuticals, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Amylin Pharmaceuticals Initiates Phase 2B Dose-Ranging Clinical Study of Pramlintide/Metreleptin Combination Treatment in Obesity
2. Amylin Pharmaceuticals to Present Novel Data on Promising Obesity Pipeline at 2008 Annual Scientific Meeting of The Obesity Society
3. Amylin and Lilly Announce Plans to Develop Pen Device for Exenatide Once Weekly
4. Amylin Pharmaceuticals Highlights New Data Supporting Therapeutic Potential of Obesity Pipeline at Obesity 2009
5. Amylin Pharmaceuticals Reports Third Quarter Financial Results
6. Amylin Pharmaceuticals and Eli Lilly and Company Statement on FDAs BYETTA(R) (Exenatide) Injection Update
7. Amylin Pharmaceuticals to Present at the 18th Annual Credit Suisse Healthcare Conference
8. Amylin Pharmaceuticals to Webcast Year-End Financial Results
9. Amylin Highlights 2010 Corporate Priorities at J.P. Morgan Healthcare Conference
10. Amylin and Takeda Announce Decision to Advance Development of Pramlintide/Metreleptin Combination Treatment for Obesity
11. Amylin Pharmaceuticals to Present at The Barclays Capital 2010 Global Healthcare Conference
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/31/2014)... 31, 2014 Mast Therapeutics, Inc. (NYSE MKT: ... for the quarter ended September 30, 2014. ... said:  "The third quarter was productive for Mast. Consistent with ... MST-188 for sickle cell disease is on track to ... have opened 50 study sites in the U.S. and ...
(Date:10/31/2014)... ARBOR, Mich. , Oct. 31, 2014 /PRNewswire/ ... immune modulators to treat autoimmune disease and cancer, ... of novel synthetic RORgamma agonist product candidates will ... Society for Immunotherapy of Cancer (SITC) being held ... & Convention Center, National Harbor, MD.  The poster, ...
(Date:10/31/2014)... 31, 2014 ThynkWare ( www.thynkware.com ) is ... text and email messages using their thoughts. ... by ThynkWare,s founder, Duane Cash , which is ... This technology allows users to control their devices in ... thought. ThynkWare provides the interface layer between ...
Breaking Medicine Technology:Mast Therapeutics Reports Third Quarter 2014 Financial Results 2Mast Therapeutics Reports Third Quarter 2014 Financial Results 3Mast Therapeutics Reports Third Quarter 2014 Financial Results 4Mast Therapeutics Reports Third Quarter 2014 Financial Results 5Mast Therapeutics Reports Third Quarter 2014 Financial Results 6Mast Therapeutics Reports Third Quarter 2014 Financial Results 7Mast Therapeutics Reports Third Quarter 2014 Financial Results 8Lycera Announces Presentation of Data on Anti-Tumor Activity of Novel Synthetic RORgamma Agonists at Society for Immunotherapy of Cancer Meeting 2ThynkWare Speech Helps Those with ALS and Locked-In Syndrome Translate Thought to Speech on Their Smartphone Devices 2
... SALT LAKE CITY, Dec. 14, 2011 Lineagen, Inc., ... linked disorders, and Fast Forward, LLC, a nonprofit subsidiary ... alliance to fund the clinical development and validation of ... of the program is to develop a test that ...
... 2011 Carl Zeiss Group continues to ...   - Vision Care business group fully consolidated ... of global economic uncertainty Carl Zeiss has ... the company generated revenues of EUR 4.237b (prior year: EUR ...
Cached Medicine Technology:Lineagen and Fast Forward Collaborate to Develop Gene and Biomarker-Based Clinical Assays for Multiple Sclerosis 2Lineagen and Fast Forward Collaborate to Develop Gene and Biomarker-Based Clinical Assays for Multiple Sclerosis 3Lineagen and Fast Forward Collaborate to Develop Gene and Biomarker-Based Clinical Assays for Multiple Sclerosis 4Carl Zeiss: Revenue Tops Four Billion Euro Mark for Very First Time 2
(Date:10/31/2014)... for low back pain caused by spinal stenosis varies ... a new report says. "Nearly 80 percent of ... in their lives, and about 30 million people a ... co-author Brook Martin, of the Dartmouth Institute of Health ... release. In spinal stenosis, thickening of tissue surrounding ...
(Date:10/31/2014)... IL – New research suggests that insomnia is a ... and other unintentional fatal injuries. The results underscore the ... the National Healthy Sleep Awareness Project. , Results show ... a dose-dependent manner with the number of insomnia symptoms ... 2.8 times more likely to die from a fatal ...
(Date:10/31/2014)... The Suspension Revolution review published by Daily Gossip ... Dan Long, a suspension training specialist. , Long ... life coach. The author of this program claims that ... impossible , The Suspension Revolution review reveals that this ... efficiency when it comes to burning fat, building muscles, ...
(Date:10/31/2014)... Florida Air Academy, the Melbourne ... grades 6-12, is taking the lead when it ... concussions, becoming the first high school in central ... Assessment and Cognitive Testing) computerized assessment to all ... grabs the headlines, and the Centers for Disease ...
(Date:10/31/2014)... Phoenix dentist , Dr. Christy, is ... Whether patients simply need routine care or have a more ... now to get that necessary care. The right dental treatments ... and even essential treatments due to financial concerns. Throughout the ... any treatments offered by the team at Christy Dental Care. ...
Breaking Medicine News(10 mins):Health News:Spinal Surgery Varies by Region in U.S.: Study 2Health News:Insomnia increases risk of motor vehicle deaths, other fatal injuries 2Health News:Suspension Revolution Review Reveals Dan Long's New Suspension Workout Plan 2Health News:Florida Air Academy Tackling Concussions Head-On 2Health News:Florida Air Academy Tackling Concussions Head-On 3Health News:Phoenix Dentist, Dr. Christy, is Now Offering Ten Percent Off On All Dental Treatments for the Month of November 2
... has a significant association with feelings of external pressure ... girls, especially those who are white, suggests a research ... Minneapolis, Minn., at SLEEP 2011, the 25th Anniversary Meeting ... Results show that pressures to have a thin body ...
... cutting-edge research that promises to revolutionise the diagnosis and treatment ... used in the long-term to develop a radical new type ... dummy to meet the different needs of individual patients. If ... market within 4 years. The research is being ...
... breakthrough by researchers at the Institut de recherches cliniques de ... a scientific journal of the Cell Press group. Led ... new requirement for the proper functioning of the Sonic Hedgehog ... proteins that gives cells the information needed for the embryo ...
... Gordon HealthDay Reporter , MONDAY, June 13 (HealthDay News) ... the park may depend on the time of the game, and ... night owl. New research on Major League Baseball players suggests ... game starts before 2 p.m., while night owls are at their ...
... Western Reserve University School of Medicine have discovered a ... to chronic health problems. If they learn to ... macrophages, "We have a shot at a novel treatment ... disease and cancer," said Mukesh K. Jain, MD, Ellery ...
... A new study published by the American Physiological Society ... 2 diabetes can begin in the womb, giving new ... disease at the center of a worldwide epidemic. The ... are even moderately undernourished while pregnant and breastfeeding, their ...
Cached Medicine News:Health News:White adolescent girls may be losing sleep from the pressure to be thin 2Health News:New software 'hearing dummies' pave the way for tailor-made hearing aids 2Health News:New software 'hearing dummies' pave the way for tailor-made hearing aids 3Health News:A scientific breakthrough at the IRCM could help understand certain cancers 2Health News:Hey, Batter: Your Sleep Habit May Affect Your Swing 2Health News:Hey, Batter: Your Sleep Habit May Affect Your Swing 3Health News:Genetic factor controls health-harming inflammation in obese 2Health News:Undernourishment in pregnant, lactating females found key to next generation's disease 2Health News:Undernourishment in pregnant, lactating females found key to next generation's disease 3
15mm Open Blades, Thumb Screw Control; in Titanium....
10mm from mid screw to tips; curved tips, in Titanium....
7mm Cross Hairs; Available in 4.5mm to 7.0mm in 0.5mm increments; Ring depth available from 2 to 4mm in 0.5mm increments.; in stainless steel....
Retractable, straight double Lancet Blade, 15 Degree Angle , available in variations; Titanium handle...
Medicine Products: