Navigation Links
Sperm Cells attracted By Ovary Scent, Even in Weakened State

A new study by scientists at Indiana University Bloomington have reported that mouse sperm cells are capable of tracking the faintest of scents. //Sperm cells were bang on target, even when ovary extracts were extremely diluted.

"Sperm are known to exhibit chemotaxis toward extracts from various female reproductive organs, but the role of chemotaxis in reproduction is not known," said IUB Associate Professor of Chemistry Stephen C. Jacobson. "The chemicals that actually attract sperm have not been identified. Systematic study of various compounds released by the female reproductive organs under various conditions might further our understanding of these processes." Understanding why, how and when sperm are attracted to ovaries may help scientists understand problems with human conception.

"Defects in sperm chemotaxis may be a cause of infertility, and consequently, sperm chemotaxis could potentially be used as a diagnostic tool to determine sperm quality or as a therapeutic procedure in male infertility," Jacobson said.

The project is a collaboration between research groups led by Jacobson and IUB Distinguished Professor of Chemistry Milos V. Novotny. Their work led to the development of a "flow-through" device, a sort of liquid treadmill for sperm cells, which allows researchers to follow the lateral movement of sperm as the cells swim through a liquid medium.

The device feeds three streams of liquid into a single chamber. Beyond the chamber, flows are split into three exit streams. Flow rate can be regulated simply by raising or lowering the height of the source medium, in this case a buffer solution. The researchers affixed a microscope and camera to the device and then recorded video of the sperm during assays.

"We combined in a microfluidic device the ability to generate a chemical gradient with transporting sperm cells to evaluate sperm chemotaxis," Jacobson said. "The use of microfluidic devices appears to be an ideal approach for precisely controlling the chemical gradient and accurately tracking chemotactic events. This combination led to greater repeatability in the experimental conditions over the course of the assays, which is currently not possible with conventional assays. These results are an important first step toward having an easy-to-use platform to rapidly evaluate and quantify chemotaxis." The researchers hope their device will help other scientists more accurately examine the chemotaxis of all types of cells. The method also eliminates the phenomenon of "trapping," which causes study results to become ambiguous.

"The ability to differentiate chemotaxis from trapping helps to determine whether sperm were attracted to the test substance or the swim velocity was reduced close to the test substance," Jacobson said. "In the latter case, the test substance may have had a negative influence on the sperm, resulting in suppression of their movement." Novotny is the Lilly Chemistry Alumni Chair in the Indiana University Bloomington Department of Chemistry, where he also directs the Institute for Pheromone Research.

Related medicine news :

1. Sperm washing helps couples – Breakthrough in focu
2. Now you can identify Sperm and Egg donors
3. Elevated Ozone Levels Hurt Sperm Count
4. Sperm washing helps couples
5. The Falling Sperm Count In Men
6. Anonymous Sperm Donor Traced On Internet
7. Declining Rates Of Sperm Donors Over The Past 5 Years
8. Sperm stem cells could be an alternative to embryonic stem cells in future
9. Sperm Retrieval, Difficult in Klinefelter’s Syndrome Patients after 35 Year
10. Researchers Identify Role Of Protein In Sperm Hyperactivation
11. Sperms not silent in the Female reproductive Tract
Post Your Comments:

(Date:6/27/2016)... ... 2016 , ... recently awarded their highest five-star rating to Best Buy ... in the United States and Canada wear eyeglasses. Once considered to be a purely ... make a fashion statement. Even celebrities use glasses as a way of creating an ...
(Date:6/26/2016)... ... , ... PawPaws brand pet supplements owned by Whole Health Supply ... health of felines. The formula is all-natural and is made from Chinese herbs that ... Cat Kidney Support Supplement Soft Chews are Astragalus Root Extract and Rehmannia Root ...
(Date:6/25/2016)... ... ... Austin residents seeking Mohs surgery services, can now turn to Dr. Jessica Scruggs ... for medical and surgical dermatology. , Dr. Dorsey brings specialization to include Mohs surgery, ... Micrographic Surgery completed by Dr. Dorsey was under the direction of Glenn Goldstein, MD, ...
(Date:6/25/2016)... ... , ... As a lifelong Southern Californian, Dr. Omkar Marathe earned his Bachelors ... Geffen School of Medicine at UCLA. He trained in Internal Medicine at Scripps Green ... hematology/oncology at the UCLA-Olive View-Cedars Sinai program where he had the opportunity to train ...
(Date:6/24/2016)... ... 24, 2016 , ... A recent article published June 14 on ... article goes on to state that individuals are now more comfortable seeking to undergo ... such as calf and cheek reduction. The Los Angeles area medical group, Beverly Hills ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... SAN CLEMENTE, Calif. , June 24, 2016  American ... function testing company, is now able to perform sophisticated lung assessments ... ndd Medical Technologies , Inc. Patients are no ...  Thanks to ndd,s EasyOne PRO ® , ARL patients like Jeanne ... needed testing done in the comfort of her own home. ...
(Date:6/24/2016)... 24, 2016   Pulmatrix, Inc ., (NASDAQ: ... inhaled drugs, announced today that it was added to ... its comprehensive set of U.S. and global equity ... an important milestone for Pulmatrix," said Chief Executive Officer ... of our progress in developing drugs for crucial unmet ...
(Date:6/23/2016)... 23, 2016  MedSource announced today that it ... software solution of choice.  This latest decision demonstrates ... to their clients by offering a state-of-the-art electronic ... establishes nowEDC as the EDC platform of choice ... clients.  "nowEDC has long been a preferred EDC ...
Breaking Medicine Technology: