Navigation Links
Sperm Cells attracted By Ovary Scent, Even in Weakened State

A new study by scientists at Indiana University Bloomington have reported that mouse sperm cells are capable of tracking the faintest of scents. //Sperm cells were bang on target, even when ovary extracts were extremely diluted.

"Sperm are known to exhibit chemotaxis toward extracts from various female reproductive organs, but the role of chemotaxis in reproduction is not known," said IUB Associate Professor of Chemistry Stephen C. Jacobson. "The chemicals that actually attract sperm have not been identified. Systematic study of various compounds released by the female reproductive organs under various conditions might further our understanding of these processes." Understanding why, how and when sperm are attracted to ovaries may help scientists understand problems with human conception.

"Defects in sperm chemotaxis may be a cause of infertility, and consequently, sperm chemotaxis could potentially be used as a diagnostic tool to determine sperm quality or as a therapeutic procedure in male infertility," Jacobson said.

The project is a collaboration between research groups led by Jacobson and IUB Distinguished Professor of Chemistry Milos V. Novotny. Their work led to the development of a "flow-through" device, a sort of liquid treadmill for sperm cells, which allows researchers to follow the lateral movement of sperm as the cells swim through a liquid medium.

The device feeds three streams of liquid into a single chamber. Beyond the chamber, flows are split into three exit streams. Flow rate can be regulated simply by raising or lowering the height of the source medium, in this case a buffer solution. The researchers affixed a microscope and camera to the device and then recorded video of the sperm during assays.

"We combined in a microfluidic device the ability to generate a chemical gradient with transporting sperm cells to evaluate sperm chemotaxis," Jacobson said. "The use of microfluidic devices appears to be an ideal approach for precisely controlling the chemical gradient and accurately tracking chemotactic events. This combination led to greater repeatability in the experimental conditions over the course of the assays, which is currently not possible with conventional assays. These results are an important first step toward having an easy-to-use platform to rapidly evaluate and quantify chemotaxis." The researchers hope their device will help other scientists more accurately examine the chemotaxis of all types of cells. The method also eliminates the phenomenon of "trapping," which causes study results to become ambiguous.

"The ability to differentiate chemotaxis from trapping helps to determine whether sperm were attracted to the test substance or the swim velocity was reduced close to the test substance," Jacobson said. "In the latter case, the test substance may have had a negative influence on the sperm, resulting in suppression of their movement." Novotny is the Lilly Chemistry Alumni Chair in the Indiana University Bloomington Department of Chemistry, where he also directs the Institute for Pheromone Research.
'"/>




Related medicine news :

1. Sperm washing helps couples – Breakthrough in focu
2. Now you can identify Sperm and Egg donors
3. Elevated Ozone Levels Hurt Sperm Count
4. Sperm washing helps couples
5. The Falling Sperm Count In Men
6. Anonymous Sperm Donor Traced On Internet
7. Declining Rates Of Sperm Donors Over The Past 5 Years
8. Sperm stem cells could be an alternative to embryonic stem cells in future
9. Sperm Retrieval, Difficult in Klinefelter’s Syndrome Patients after 35 Year
10. Researchers Identify Role Of Protein In Sperm Hyperactivation
11. Sperms not silent in the Female reproductive Tract
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/20/2017)... ... ... Trials I Face to Receive God’s Grace”: a mesmerizing take on one man’s ... one’s life through God. “The Trials I Face to Receive God’s Grace” is the ... a love for writing. Green feels that expressing his feelings through prayer will present ...
(Date:9/20/2017)... ... ... “Psalms of Humidity”: is a fascinating depiction of daily struggles and the ... closer to God. “Psalms of Humidity” is the creation of published author, David Waldrop, ... his life are the very same things that have shaped him into the man ...
(Date:9/19/2017)... ... September 19, 2017 , ... With a ... have raised more than $15,000 in just a couple of weeks for those ... matches and world-class instructor seminars, organizers expect to double those initial funds with ...
(Date:9/19/2017)... ... September 19, 2017 , ... ... Safety for the President’s Malaria Initiative (PMI) Africa Indoor Residual Spraying (AIRS) ... Action Award. , The Innovation to Action Award, a USAID Catalyst Award, ...
(Date:9/19/2017)... ... September 19, 2017 , ... MelaKids, a Laredo-based company, has introduced a ... When we’re born, Nature gives us a full supply of melanin – in the ... lose this natural glare-reducing pigment; however, around the age of thirty, we develop a ...
Breaking Medicine News(10 mins):
(Date:9/6/2017)... N.Y. , Sept. 6, 2017   PDI , ... announced it will host an educational session focused on ... bloodstream infection (CLABSI) prevention at the 2017 Annual Scientific ... which will take place at the Phoenix ... from Sept. 16-19, will also feature PDI,s ...
(Date:9/5/2017)... Sept. 5, 2017  Xyntek Inc. has announced another milestone in their continued ... office to meet the growing demands of customer engagements regionally.  ... Xyntek's new Midwest office is located at 318 West Adams Street, ... ... regionally. ...
(Date:9/1/2017)... Michael Penna , President and CEO ... for growth in his response to the July 13, ... seeking a buyer for eMDs. Penna,s company, Complete HealthCare ... Value Added Reseller and national leader in the independent ... "As the healthcare market continues to dictate consolidation, healthcare ...
Breaking Medicine Technology: