Navigation Links
Growth Factors Given With Chemotherapy may Increase Risk of Blood Diseases

Women with breast cancer who receive compounds that stimulate white blood cell production to help their bodies better tolerate chemotherapy are at an increased// risk of developing a type of leukemia or a condition called myelodysplastic syndrome, according to a new study in the February 7 Journal of the National Cancer Institute. The authors note that the absolute risk of the conditions is very small, but that risk should still be taken into consideration when making treatment decisions.

The growth factors granulocyte or granulocyte-macrophage colony-stimulating factor (G-CSF or GM-CSF) have been used to reduce the risk of infections from neutropenia, an abnormally low count of a certain type of white blood cell that helps control infections. Chemotherapy destroys these cells, and it is difficult for the body to quickly replace them.

However, there is some concern that these growth factors may keep cells alive that have been mutated by chemotherapy. Ordinarily, certain cell processes would recognize such damage and instruct the cell to die, but growth factors may save the mutant cell, allowing it to develop into a cancer called acute myelocytic leukemia (AML). There's also concern about the risk of a disease called myelodysplastic syndrome (MDS), in which the bone marrow—which produces blood cells—does not function normally. Indeed, some studies have hinted that cancer patients who receive growth factors with chemotherapy may have an increased risk of these two diseases.

Dawn Hershman, M.D., of the Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center and New York Presbyterian Hospital, and colleagues set out to determine the association between G-CSF or GM-CSF use and the risk of AML or MDS among women treated with chemotherapy for early-stage breast cancer. Using a database that links cancer registry data from the Surveillance, Epidemiology, and End Results (SEER) program with data from Medicare, th
'"/>




Page: 1 2 3

Related medicine news :

1. Anti-Cancer Drug Restores Normal Cell Growth
2. Low-dose Growth Hormone (GH) with diet and exercise may help weight loss
3. Human Growth Hormone Found To be Dangerous For Human Use
4. Stem Cells Found To Offer Promise For Hair Growth
5. Fish Found To Improve Fetal Growth
6. Growth Patterns In Childhood Could Predict Breast Cancer Later In Life
7. Stopping The Growth Of Viruses
8. Stopping The Growth Of Viruses
9. Turmeric Found To Slow Down Melanoma Growth
10. Protein acts as "Master Switch" that cuts off cells Cancer-Growth machinery
11. Record Growth Of Soya-Based Dairy Alternatives Over The Past Year In European Markets
Post Your Comments:
(Date:4/22/2014)... is available in German . ... intracellular signaling molecules, but their mode of action is ... cellular function and behavior, while at high concentrations they ... DNA. To analyze how redox signaling unfolds in single ... technique has been developed jointly by the teams of ...
(Date:4/22/2014)... Nearly 7 in 10 Americans support mandated coverage of ... by researchers at the University of Michigan Health System. ... age of 18 at home, and adults with private ... adults to support universal coverage of birth control medications, ... Journal of the American Medical Association ( JAMA ...
(Date:4/22/2014)... (trade name: NovoEight) has been approved since November 2013 ... with haemophilia A. In an early benefit assessment pursuant ... for Medicinal Products" (AMNOG), the German Institute for Quality ... new active ingredient offers an added benefit over the ... an added benefit of turoctocog alfa is not proven. ...
(Date:4/22/2014)... 22, 2014) Cedars-Sinai stroke intervention researchers have been ... Stroke, part of the National Institutes of Health, will ... Phase II clinical trial of an experimental drug for ... in combination with recombinant tissue plasminogen activator, or rtPA ... strokes shortly after onset. In laboratory rodent studies, 3K3A-APC, ...
(Date:4/22/2014)... have found that the anxiety experienced with a ... impact a woman,s overall well-being. Their findings are ... was published online in the April 21, 2014 ... 40 to 60 percent of women who undergo ... experience a false-positive mammogram. Such mammograms require additional ...
Breaking Medicine News(10 mins):Health News:Neuroimaging: Live from inside the cell 2Health News:More than two-thirds of Americans support mandated coverage of birth control in health plans 2Health News:Turoctocog alfa in patients with hemophilia A: Added benefit not proven 2Health News:Turoctocog alfa in patients with hemophilia A: Added benefit not proven 3Health News:$8 million NIH grant will fund multicenter clinical trial of stroke intervention drug 2Health News:$8 million NIH grant will fund multicenter clinical trial of stroke intervention drug 3Health News:False-positive mammogram anxiety has limited impact on women's well-being 2
... Depression Management Program Employs Telephone Contact in TreatmentCOLUMBIA, S.C., ... (CBA) was awarded Silver Honors for Health ... organization, URAC . The honor was ... Health Care Consumer Empowerment and Protection Awards Gala ...
... to Draw Attention to Connecticut,s Growing Burden of Chronic Disease ... Loss Caused by CrisisHARTFORD, Conn., April 6 National and ... joining to launch a Partnership to call for comprehensive health ... disease here in Connecticut and across the nation. , ...
... study identify a biomarker that may be useful for predicting ... in young children. The research, published by Cell Press in ... , also provides new information about the molecular signals that ... cancer. , Retinoic acid (RA) is a metabolite of Vitamin ...
... nation to receive accreditationGREEN BAY, Wis., ... one of the first four hospitals in the ... Program for Breast Centers (NAPBC), administered by the ... program in Wisconsin to earn this recognition.(Logo: ...
... the level of patient care and streamline workflow for more efficient ... from the 2009 Annual HIMSS Conference & Exhibition at McCormick Place ... , ... Chicago, IL (PRWEB) April 6, 2009 -- ...
... A ,Biggest Loser, Finalist from the Lehigh ... Pa., April 6 Department of Health Secretary Everette James ... lunchtime fitness walk around the Capitol complex to bring awareness ... their own health. "As the state agency with ...
Cached Medicine News:Health News:Companion Benefit Alternatives Awarded Silver Honors for Best Practices in Health Plans and Health Networks by URAC 2Health News:Companion Benefit Alternatives Awarded Silver Honors for Best Practices in Health Plans and Health Networks by URAC 3Health News:Bipartisan CT Coalition Forms to Fight Spiraling Health Care Costs 2Health News:Biomarker associated with poor outcome in aggressive childhood cancer 2Health News:Aurora BayCare is Wisconsin's First Nationally Accredited Breast Program 2Health News:Orion Health Concerto Whiteboard Helps Emergency Rooms and Wards Track Patient Status 2Health News:Orion Health Concerto Whiteboard Helps Emergency Rooms and Wards Track Patient Status 3Health News:Secretary of Health 'Walks the Walk' to Kick Off National Public Health Week 2
(Date:1/15/2014)... Mass. , Jan. 15, 2014  Zafgen, Inc., ... unmet needs of severely obese patients, today announced ... beloranib, a selective inhibitor of methionine aminopeptidase 2 ... severe form of genetic obesity.  These results showed ...
(Date:1/14/2014)... The Brandeis Medical Center, led by Dr. Emmanuel Brandeis , ... laser tattoo removal experience with the advanced Astanza Duality laser and ... quality cosmetic services with cutting edge medical technology and offering expert ... has seen a dramatic increase in the presence of ...
(Date:1/14/2014)... CLEVELAND , Jan. 14, 2014 NineSigma ... will hold its Innovation Leadership Summit , May ... in Cleveland Ohio . ... innovators and organizations committed to breakthrough achievements through open ...
Breaking Medicine Technology:Zafgen Announces Initial Results from Phase 2a Study of Beloranib in Patients with Prader-Willi Syndrome 2Zafgen Announces Initial Results from Phase 2a Study of Beloranib in Patients with Prader-Willi Syndrome 3Zafgen Announces Initial Results from Phase 2a Study of Beloranib in Patients with Prader-Willi Syndrome 4Beverly Hills Physician Features Tattoo Removal with the Astanza Duality Laser, Offers $99 Special 2Expect the Unexpected from Leading Global Innovators at NineSigma Leadership Summit, Sharing Winning Strategies to Advance Innovation 2Expect the Unexpected from Leading Global Innovators at NineSigma Leadership Summit, Sharing Winning Strategies to Advance Innovation 3Expect the Unexpected from Leading Global Innovators at NineSigma Leadership Summit, Sharing Winning Strategies to Advance Innovation 4
The Trans-Blot transfer cell, used with the included PowerPac 200 power supply, performs efficient, high-intensity electrophoretic transfers. The Trans-Blot cell offers many advantages....
... specifically designed to work with the EC120 ... a small tank blotter that incorporates the ... buffer requirements and fast transfer rates), with ... blotting such as arcing and buffer depletion. ...
... Semi-Dry Blotting System. 20cm x ... Southern gels reliably and quickly. The ... are durable and corrosion free. These ... excellent transfers. Also available in 35cm ...
... SD semi-dry transfer cell allows ... Using a platinum-coated titanium plate ... stainless steel plate as the ... transfers in a horizontal configuration ...
Medicine Products: