Navigation Links
Drug for Blood Pressure also Treats Lung Cancer

tensin-converting enzyme (ACE) inhibitors. These drugs, which include Capoten? and Lotensin?, increase levels of angiotensin-(1-7) in the bloodstream.

Gallagher and Tallant have been working with angiotensin -(1-7) for years as members of the Hypertension and Vascular Research Center faculty. Carlos M. Ferrario, M.D., center director, discovered angiotensin-(1-7) in 1988, and found it to be a critical element of the blood pressure control system. The hormone relaxes (dilates) the walls of the blood vessels, causing blood pressure to be lowered. ACE inhibitors may work by increasing angiotensin-(1-7).

For the current study, human cancer cells were obtained from the American Tissue Culture Collection. Mice were inoculated with the cells and 32 days later were randomly selected to receive either an intravenous treatment of angiotensin-(1-7) or saline for 28 days. The blood levels of angiotensin-(1-7) achieved through treatment were similar to levels in humans being treated with an ACE inhibitor.

'The study may explain the molecular mechanism for a decreased risk of lung cancers in patients with high blood pressure taking ACE inhibitors,' said Tallant.

The researchers believe that angiotensin-(1-7) reduces cyclooxygenase-2 (COX-2), an enzyme that regulates cell growth. COX-2 is found at higher levels in 70 to 90 percent of malignant lung tumors.

Theoretically, drugs to reduce COX-2 would also be effective at shrinking tumors. But the drugs, such as Vioxx?, have been shown to increase the risk of heart attack, stroke and angina.

The researchers said that additional studies of angiotensin-(1-7) are needed, but that the hormone shows promise as a lung cancer treatment – either alone or in combination with other drugs.

Source-Eurekalert
'"/>




Page: 1 2

Related medicine news :

1. Recommendations for Treatment of Blood Pressue
2. Blood Cells Capable of Regenerating Liver
3. Blood clots likely in long travel
4. Hemochromatosis Patients Blood is Safe
5. Blood transfusions beneficial after heart attacks
6. Blood Pressure Drug may slow wasting in burn victims
7. Levels Of Blood Proteins May Help Heart Disease Care
8. Blood test may identify ovarian cancer
9. A Blood test for suicide risk?
10. Blood Pressure Drugs maintain muscle strength
11. Blood test diagnoses heart failure in short time
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Drug for Blood Pressure also Treats Lung Cancer

(Date:9/2/2015)... ... September 02, 2015 , ... Ovarian cancer continues to be the deadliest ... getting ovarian cancer in her lifetime is approximately 1 in 75. This year it ... and 14,000 will die. , There is no test to detect ovarian cancer. ...
(Date:9/2/2015)... (PRWEB) , ... September 02, 2015 , ... ... PHYTOMER, the pioneer in marine cosmetics introduces PIONNIÈRE XMF Perfection Youth Rich ... new cream combines breakthrough biotechnological anti-aging power with a lipid-replenishing marine oil for ...
(Date:9/2/2015)... , ... September 02, 2015 , ... ... business services, has been named to the Inc. 5000 List, an independent ... publishing this list for 34 years, and this achievement puts Canopy in rarefied ...
(Date:9/2/2015)... ... September 02, 2015 , ... Traveling to the Caribbean can be an amazing ... and fauna. , Lifestyle Holidays Vacation Club knows that Puerto Plata ... experience that much better, Lifestyle Holidays Vacation Club has put together its list of ...
(Date:9/1/2015)... FL (PRWEB) , ... September 01, 2015 , ... September ... about this disease that affects more than 233,000 men each year in the United ... is the most common non-skin cancer in America, affecting 1 in 7 men. One ...
Breaking Medicine News(10 mins):Health News:National Ovarian Cancer Coalition's DFW Chapter Features First Annual Teal Lights Display This Friday, September 4th, "National Wear Teal Day" 2Health News:National Ovarian Cancer Coalition's DFW Chapter Features First Annual Teal Lights Display This Friday, September 4th, "National Wear Teal Day" 3Health News:Phytomer announces PIONNIÈRE XMF Perfection Youth Rich Cream 2Health News:Phytomer announces PIONNIÈRE XMF Perfection Youth Rich Cream 3Health News:Phytomer announces PIONNIÈRE XMF Perfection Youth Rich Cream 4Health News:Canopy Partners Named to 2015 Inc. 5000 Fastest Growing Companies List 2Health News:Lifestyle Holidays Vacation Club Lists 3 Things to Consider When On a Puerto Plata Vacation 2Health News:Lifestyle Holidays Vacation Club Lists 3 Things to Consider When On a Puerto Plata Vacation 3Health News:September is Prostate Cancer Awareness Month 2Health News:September is Prostate Cancer Awareness Month 3
... in BJOG: An International Journal of Obstetrics and Gynaecology ... and placental abruption during the subsequent pregnancies of ... ,Placental praevia is defined as the implantation of ... the cervix. Placenta abruption is the premature separation of ...
... a campaign to encourage Hispanics to eat healthier food, ... U.S. Hispanics increased from 11.6% in 1991 to 23.7% ... obese and two times more likely to have diabetes ... ,LNC's campaign features a "Latin American ...
... their lives to work- related cancers and heart attacks can ... laws state that they no longer need to prove ... due the dead workers family. , The ... will be presumed to have been work-related when contracted by ...
... the US. A Defence Department panel has warned that ... serious challenge on two fronts. ,One, soldiers are ... at the current level of staffing and funds, the military ... necessary statement. ,In a damning revelation, the ...
... is no dearth of "anti-aging" products and surgeries in ... women go for them not just to enhance their looks, ... competitive enough in the market place, many observers point out. ... toxin. The toxin blocks the transmission of acetylcholine from the ...
... in 70 schoolchildren, available data says. The question is whether ... joint team of scientists from the King's College London ... up a seven-year study and hope to rope in 480 ... studied are between four and 11 months and already have ...
Cached Medicine News:Health News:Placental Problems in Women Linked With Caesarean Section 2Health News:Ontario Grants Fast-Track Compensation Rights for Work-Related Illnesses 2Health News:Ontario Grants Fast-Track Compensation Rights for Work-Related Illnesses 3Health News:One Third of US Troops Suffer from Mental Health Problems 2Health News:One Third of US Troops Suffer from Mental Health Problems 3Health News:More and More American Women Go for Facelifts to Get Jobs 2Health News:UK Scientists to Undertake Seven Year Study of Peanut Allergy 2
(Date:9/1/2015)... , September 2, 2015 ... for global clinical trials review of H2, 2015 ... with an objective to enhance decision making capabilities ... Complete report on Keratoconus market clinical trials review ... 10 institutes / government organizations and supported with ...
(Date:9/1/2015)... THOUSAND OAKS, Calif. , Sept. 1, 2015 ... a neuroscience collaboration with Novartis in the areas ... Amgen,s potential entry into Alzheimer,s disease by teaming ... validated Alzheimer,s disease program directed at genetically predisposed ... collaboration also enables Amgen to focus on the commercialization ...
(Date:9/1/2015)... 1, 2015 Nevro Corp. (NYSE: NVRO ... innovative evidence-based solutions for the treatment of chronic pain, ... response to the Patent Trial and Appeals Board (PTAB) ... review (IPR), filed by a unit of Boston Scientific ... Patent No. 8,359,102 (the ,102 patent). The ,102 patent is ...
Breaking Medicine Technology:Keratoconus Market Clinical Trials Review H2 2015 Global Research Report 2Keratoconus Market Clinical Trials Review H2 2015 Global Research Report 3Keratoconus Market Clinical Trials Review H2 2015 Global Research Report 4Keratoconus Market Clinical Trials Review H2 2015 Global Research Report 5Amgen Enters Into Neuroscience Collaboration With Novartis For Alzheimer's Disease And Migraine Programs 2Amgen Enters Into Neuroscience Collaboration With Novartis For Alzheimer's Disease And Migraine Programs 3Amgen Enters Into Neuroscience Collaboration With Novartis For Alzheimer's Disease And Migraine Programs 4Amgen Enters Into Neuroscience Collaboration With Novartis For Alzheimer's Disease And Migraine Programs 5Amgen Enters Into Neuroscience Collaboration With Novartis For Alzheimer's Disease And Migraine Programs 6Amgen Enters Into Neuroscience Collaboration With Novartis For Alzheimer's Disease And Migraine Programs 7Amgen Enters Into Neuroscience Collaboration With Novartis For Alzheimer's Disease And Migraine Programs 8Amgen Enters Into Neuroscience Collaboration With Novartis For Alzheimer's Disease And Migraine Programs 9Nevro Announces Submission of Preliminary Response to the Patent Trial and Appeals Board 2
... Corporation (NYSE: HLS ) today announced it will participate ... on Nov. 17-18, 2009. , HealthSouth President and Chief ... 17, 2009, at 3:10 p.m. ET. The presentation will be ... by clicking on an available link. , About ...
... 30 When the prestigious British medical journal ... treatment guideline papers aimed at the resource-diverse nations of ... developed by the Breast Health Global Initiative (BHGI) based ... important affirmation that the BHGI,s unique resource-stratification approach to ...
Cached Medicine Technology:Cancer Treatment Guidelines for Diverse Asian Economies Use Model Developed at Fred Hutchinson Cancer Research Center 2Cancer Treatment Guidelines for Diverse Asian Economies Use Model Developed at Fred Hutchinson Cancer Research Center 3
Thesystem combines an exclusive dual light-source design and a versatile sample compartment to provide solid, reliable performance....
Inquire...
The Spex SkinSkan is the only in-vivo, fibre-optic spectrofluorometer designed specifically for skin-fluorescence measurements. It is also ideal for many remote sensing steady-state fluorescence appl...
The unique RF-1501 optical design provides exceptional sensitivity in an incredibly compact instrument....
Medicine Products: