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Antibiotic, Gene Therapy Help Treat Angina

, is this (infection) an innocent bystander or a culprit," Kaski said. Although the antibiotic worked, "the mechanism by how the antibiotic was effective was not very clear," he said.

Dr. David A. Meyerson, a cardiologist at Johns Hopkins Medical Center in Baltimore and a spokesman for the American Heart Association, said it's "too soon to recommend use of antibiotics to either treat or prevent heart disease," and it's unclear how the antibiotic is producing this effect.

On the issue of gene therapy, however, Meyerson said this holds a great deal of promise. "This is truly exciting research," Meyerson said. "Currently, we have no adequate therapy for those patients with disabling angina already on maximum medications and whose anatomy does not permit angioplasty or bypass surgery. Ultimately, we would hope to use similar techniques to prevent heart attacks and stroke."


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