Navigation Links
Virus and genes involved in causation of schizophrenia
Date:3/8/2013

Viruses and genes interact in a way that may increase the risk of developing schizophrenia significantly. This happens already in the developing foetus.

An international team of scientists led by Aarhus University, Denmark, has made this discovery. As the first in the world, they scanned the entire genome of hundreds of sick and healthy people to see if there is an interaction between genes and a very common virus - cytomegalovirus - and to see whether the interaction influences the risk of developing schizophrenia.

And it does.

Women that have been infected by the virus - and around 70 % has - will have a statistically significant increased risk of giving birth to a child who later develops schizophrenia if the child also has the aforementioned gene variant. This variant is found in 15 percent. The risk is five times higher than usual, the researchers report in Molecular Psychiatry.

No cause for alarm

People infected with cytomegalovirus most often do not know it, as the infection by the virus, which belongs to the herpes virus family, is usually very mild. But the researchers stress that there is no cause for alarm - even if both risk factors are present in mother and child, there may be a variety of other factors that prevents disease development in the child.

But as schizophrenia affects 1 per cent of the global population, this new knowledge is very important.

"In the longer term, the development of an effective vaccine against cytomegalovirus may help to prevent many cases of schizophrenia," says Professor of Medical Genetics at Aarhus University, Anders Brglum.

"And our discovery emphasizes that mental disorders such as schizophrenia may arise in the context of an interaction between genes and biological environmental factors very early in life."


'/>"/>

Contact: Anders Borglum
anders@hum-gen.au.dk
45-60-20-27-20
Aarhus University
Source:Eurekalert

Page: 1

Related medicine news :

1. Merck scientist Daria Hazuda presents Bernard Fields Lecture at 20th Conference on Retroviruses and Opportunistic Infections (CROI)
2. Defective virus surprisingly plays major role in spread of disease, UCLA life scientists report
3. UV-Aid New Technology Utilizes Hydroxyls to Eliminate Bacteria and Viruses Helping Prevent Colds, Flu, and Ear Infections
4. Virus shows promise as prostate cancer treatment
5. Study reveals new clues to Epstein-Barr virus
6. Emerging SARS-Like Virus Well-Suited to Attack Humans: Study
7. Vanderbilt study reveals clues to childhood respiratory virus
8. UNC researchers discover gene that suppresses herpesviruses
9. HIV-Like Virus Arose in Primates Millions of Years Ago, Scientists Say
10. Temple scientists find cancer-causing virus in the brain, potential connection to epilepsy
11. Vaccinating children against rotavirus may indirectly protect adults too, study finds
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/2/2016)... ... ... On Dec. 2, 2016, CURE® magazine will host the 4th Annual MPN ... Heroes—eight individuals who have made a difference in the field of rare blood cancers ... demonstrating leadership within the MPN community and/or a commitment to individual patients. , This ...
(Date:12/2/2016)... , ... December 02, 2016 , ... ... the Dothan-Wiregrass Area in Alabama are expected to attend the UNCF Dothan-Wiregrass Mayor’s ... help provide scholarship funds for area students and operating support to UNCF-member institutions, ...
(Date:12/2/2016)... California (PRWEB) , ... December 02, 2016 , ... ... professionals, proudly announces the launch of its 60-day free trial program for all ... trip shipping make the offer a truly hassle free experience. , FlexiSpot’s unique ...
(Date:12/2/2016)... ... December 02, 2016 , ... The annual time frame to change Medicare ... Period), is ending December 7th. Currently-enrolled Medicare beneficiaries who are looking to switch from ... (Part D) need to make changes during this period order for their new policy ...
(Date:12/2/2016)... ... 02, 2016 , ... With the number of pain management programs available for ... find the one that works for them. When an inventor from Suisun City, Calif., ... and decided to share it with others. , He developed a prototype for PRO ...
Breaking Medicine News(10 mins):
(Date:12/2/2016)... Research and Markets has announced the addition of Jain ... and Companies" to their offering. ... , , Drug ... market value of drug delivery technologies and the anticancer drugs are ... to organs involved and the types of cancer as well as ...
(Date:12/2/2016)... -- Around the corners of world, cancer has infused ... present over earth. Cancer has become one of those ... time this is because of the increasing incidence rates ... steady increase in global cancer incidence with its associated ... of treatment, there is increasing interest in this stringent ...
(Date:12/2/2016)... -- Allergan plc (NYSE: AGN ), a leading ... announced Accelerated Share Repurchase (ASR) Program. Logo - ... , ... announced, the Company entered into a variable tenor ASR arrangement ... $10 billion of its ordinary shares. Approximately 40.5 million shares ...
Breaking Medicine Technology: