Navigation Links
UNC neuroscientists discover new 'mini-neural computer' in the brain
Date:10/27/2013

n lab at the University of North Carolina. They used patch-clamp electrophysiology to attach a microscopic glass pipette electrode, filled with a physiological solution, to a neuronal dendrite in the brain of a mouse. The idea was to directly "listen" in on the electrical signaling process.

"Attaching the pipette to a dendrite is tremendously technically challenging," Smith said. "You can't approach the dendrite from any direction. And you can't see the dendrite. So you have to do this blind. It's like fishing if all you can see is the electrical trace of a fish." And you can't use bait. "You just go for it and see if you can hit a dendrite," he said. "Most of the time you can't."

But Smith built his own two-photon microscope system to make things easier.

Once the pipette was attached to a dendrite, Smith's team took electrical recordings from individual dendrites within the brains of anesthetized and awake mice. As the mice viewed visual stimuli on a computer screen, the researchers saw an unusual pattern of electrical signals bursts of spikes in the dendrite.

Smith's team then found that the dendritic spikes occurred selectively, depending on the visual stimulus, indicating that the dendrites processed information about what the animal was seeing.

To provide visual evidence of their finding, Smith's team filled neurons with calcium dye, which provided an optical readout of spiking. This revealed that dendrites fired spikes while other parts of the neuron did not, meaning that the spikes were the result of local processing within the dendrites.

Study co-author Tiago Branco, PhD, created a biophysical, mathematical model of neurons and found that known mechanisms could support the dendritic spiking recorded electrically, further validating the interpretation of the data.

"All the data pointed to the same conclusion," Smith said. "The dendrites are not passive integrators of sensory-driven input; the
'/>"/>

Contact: Mark Derewicz
mark.derewicz@unch.unc.edu
919-923-0959
University of North Carolina Health Care
Source:Eurekalert  

Page: 1 2 3

Related medicine news :

1. Johns Hopkins neuroscientists win National Academy of Science Awards
2. Neuroscientists find excessive protein synthesis linked to autistic-like behaviors
3. John Templeton Foundation grant supports Princeton neuroscientists to study cognitive control
4. Discover Step-By-Step Plans On How To Learn French Fast With The “Rocket French Premium” Program – Vkoolelite
5. Discover How to Determine Baby Gender With the “Prince Or Princess” Book – Vkoolelite
6. Biosimulation Market (Drug Discovery & Development) Worth $1.2 Billion by 2017 - New Report by MarketsandMarkets
7. Tear Film Evaporation Begins at Birth Water and Health Researcher Discovers
8. New Case Management Order in New Jersey DePuy ASR Recall Litigation Extends Discovery to June 2014, More than 650 Metal Hip Lawsuits Filed in Consolidated Proceeding
9. Discover 13 Natural Tips for Whitening Skin – V kool
10. The Producers of the In View Series Announce Upcoming Airing on the Discovery Channel
11. Ethicon Transvaginal Mesh Lawsuits Move Forward, With Scheduling of Discovery Conferences in Federal Vaginal Mesh Litigation, Bernstein Liebhard LLP Reports
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
UNC neuroscientists discover new 'mini-neural computer' in the brain
(Date:9/2/2014)... believe that marijuana is not addictive, but a new ... able to obtain and consume cannabis legally for medical ... likely to perceive it as addictive or harmful," study ... Center for Addiction Medicine, said in a hospital news ... have significant consequences, and we know that among adolescents ...
(Date:9/2/2014)... PA (PRWEB) September 02, 2014 ... communications and education, is proud to announce the acquisition ... clinical resource center designed for healthcare professionals who integrate ... offers practitioners comprehensive access to:, , ... Dedicated topic centers for diabetes, oncology, renal ...
(Date:9/2/2014)... Mass. (PRWEB) September 02, 2014 Healthcare ... latest and most complete oncology guidelines available at the ... Health and the National Comprehensive Cancer Network® ... with other evidence and guidelines in the content available ... , NCCN, a not-for-profit alliance of 25 of ...
(Date:9/2/2014)... from cancer surgery may be influenced by more ... Family conflicts and other non-medical problems may raise ... study has found. Addressing such quality-of-life issues before ... recoveries and save health care dollars, the research ... patients, and found that patients with a poor ...
(Date:9/2/2014)... New research involving mice suggests that the key to ... medicine cabinet. In a report published in the ... that macrophages from the lungs of old mice had ... from young mice, but these changes were reversed by ... consequences on immune function," said Joanne Turner, Ph.D., a ...
Breaking Medicine News(10 mins):Health News:'Pot Addiction' May Be Real, Study Suggests 2Health News:HMP Communications Holdings, LLC, Acquires Nutrition411.com 2Health News:DynaMed™ to Utilize Information from the National Comprehensive Cancer Network® 2Health News:DynaMed™ to Utilize Information from the National Comprehensive Cancer Network® 3Health News:DynaMed™ to Utilize Information from the National Comprehensive Cancer Network® 4Health News:Family conflicts, other non-physical worries before cancer surgery raise patients' complication risk 2
... calls for specialized pediatric care, researchers say , ... to account for about 44 percent of the estimated ... earthquake -- information that could be used to guide ... the team at Children,s Hospital Los Angeles and the ...
... report using treatments, study finds, , THURSDAY, Jan. 28 ... adolescents in the United States use complementary or alternative ... researchers. , Most of these children have serious chronic ... effectiveness of the alternative remedies, especially when they are ...
... , PALM CITY, Fla. , ... Sheets: CTYX) is pleased to announce that it has secured ... U.S. Trademark #3,739,453 for the protection of the MedFlash name, ... Cl.: 9 designation in class 9 (U.S. CLS. 21, 23, ...
... Consumer survey results indicate ,having work done, not taboo ... Cosmetic surgery is everywhere these days: TV, magazines, the ... indeed more comfortable talking about cosmetic surgery than ever before. ... of Cosmetic Surgery, 71 percent of respondents think society is ...
... , , , , , ... Jan. 28 /PRNewswire-Asia-FirstCall/ -- Biostar,Pharmaceuticals, Inc. (OTC Bulletin ... and supplier of pharmaceutical,products and medical nutrients addressing a ... January 22, 2010 , its Board of Directors had,appointed ...
... ... today that it has been selected by Central Garden & Pet Company (NASDAQ:CENT) as ... ... -- SiteHawk, the leading MSDS and chemical data management company, announced today that it ...
Cached Medicine News:Health News:Haitian Children Need Specific Relief Efforts 2Health News:Kids' Use of Alternative Therapies Often Mimics Parents' 2Health News:Connectyx Granted U.S. Trademark for MedFlash(R) 2Health News:Connectyx Granted U.S. Trademark for MedFlash(R) 3Health News:Society More Open Than Ever About Cosmetic Surgery 2Health News:Biostar Pharmaceuticals, Inc. Announces Change of Auditor 2Health News:Biostar Pharmaceuticals, Inc. Announces Change of Auditor 3Health News:Central Garden & Pet Selects SiteHawk as Its MSDS Management Provider 2
(Date:9/2/2014)... , Spanien, September 2, 2014 ... Das auf dem ESC-Kongress 2014 präsentierte ... Behandlung und Behandlungsergebnisse von schlaganfallgefährdeten Patienten ... Die Daten der ... Patienten, einer innovativen und unabhängigen Forschungsinitiative ...
(Date:9/2/2014)... Sept. 2, 2014 Particle Sciences, the leading ... investment in development and manufacturing capabilities with the addition ... Mueller , Particle Sciences, Associate Director Clinical Production, "The ... clean room square footage, equipment and staff across the ... company now has over 6000ft 2 of operating ...
(Date:9/2/2014)... , Sept. 2, 2014  Edison Nation Medical, ... partnership with the American Association for Respiratory Care ... respiratory care specialists. Edison Nation Medical, which brings ... business to commercialize their innovation ideas, will work ... of more than 50,000 respiratory therapists in bringing ...
Breaking Medicine Technology:Daten aus dem globalen Register zur Behandlung von Vorhofflimmern zeigen, dass antithrombotische Wirkstoffe zur Verhinderung von Schlaganfällen nicht optimal genutzt werden 2Daten aus dem globalen Register zur Behandlung von Vorhofflimmern zeigen, dass antithrombotische Wirkstoffe zur Verhinderung von Schlaganfällen nicht optimal genutzt werden 3Daten aus dem globalen Register zur Behandlung von Vorhofflimmern zeigen, dass antithrombotische Wirkstoffe zur Verhinderung von Schlaganfällen nicht optimal genutzt werden 4Daten aus dem globalen Register zur Behandlung von Vorhofflimmern zeigen, dass antithrombotische Wirkstoffe zur Verhinderung von Schlaganfällen nicht optimal genutzt werden 5Daten aus dem globalen Register zur Behandlung von Vorhofflimmern zeigen, dass antithrombotische Wirkstoffe zur Verhinderung von Schlaganfällen nicht optimal genutzt werden 6Daten aus dem globalen Register zur Behandlung von Vorhofflimmern zeigen, dass antithrombotische Wirkstoffe zur Verhinderung von Schlaganfällen nicht optimal genutzt werden 7Daten aus dem globalen Register zur Behandlung von Vorhofflimmern zeigen, dass antithrombotische Wirkstoffe zur Verhinderung von Schlaganfällen nicht optimal genutzt werden 8Daten aus dem globalen Register zur Behandlung von Vorhofflimmern zeigen, dass antithrombotische Wirkstoffe zur Verhinderung von Schlaganfällen nicht optimal genutzt werden 9Daten aus dem globalen Register zur Behandlung von Vorhofflimmern zeigen, dass antithrombotische Wirkstoffe zur Verhinderung von Schlaganfällen nicht optimal genutzt werden 10Daten aus dem globalen Register zur Behandlung von Vorhofflimmern zeigen, dass antithrombotische Wirkstoffe zur Verhinderung von Schlaganfällen nicht optimal genutzt werden 11Particle Sciences Expands Drug Eluting Device Capabilities and Overall Clinical Trial Manufacturing Resources 2Edison Nation Medical and AARC Team Up To Promote Innovation in Respiratory Care 2Edison Nation Medical and AARC Team Up To Promote Innovation in Respiratory Care 3
... Systems, Inc., today announced its nGage™ system has ... monitoring system in the United States.  The nGage ... cleansings. Hospitals have experienced an average ... implementation of the Proventix monitoring system. This improvement ...
... Pa., Nov. 29, 2011 Winter brings a whole set ... even worse for the 7.5 million Americans who suffer from ... from sunlight and other environmental factors rob the skin of ... Additionally, winter colds weaken the immune system, making it harder ...
Cached Medicine Technology:Proventix's nGage™ the Most Widely Used Automated Healthcare Hand Hygiene Monitoring System in the United States 2Proventix's nGage™ the Most Widely Used Automated Healthcare Hand Hygiene Monitoring System in the United States 3PhotoMedex Helps Psoriasis Patients Ease Winter Skin Care Woes 2PhotoMedex Helps Psoriasis Patients Ease Winter Skin Care Woes 3PhotoMedex Helps Psoriasis Patients Ease Winter Skin Care Woes 4
... Insertion Through A 1.0mm Incision., ,Special Direct ... ... Comfortable Approach., ,Recessed Jaws For Improved Sub-Incisional ... Of Jaws During Sterilization., ,Reusable, Autoclaveable, Guaranteed ...
The New Easy-To-Use Disposable Diamond Knife Cleaning System Can Remove Even Baked-On Debris In Seconds. It Is Much More Effective Than Steam Or Blocks Of Styrofoam, Much Safer For Employees As Wel...
... Corneal Gauges Allowing The Exact,Outer Diameter Measurement ... With 0.25mm ,Increments.,Easy And Quick To Use, ... And Place Over A Cornea For Confirmation ... The USA, ...
... Gauge Measures 360 Degrees & Can Be Set ... Cornea. 7mm Inner Diameter & 14mm Outer Diameter ... Astigmatism Gauge That Can Be Set For AKs, ... Around The Globe., ,Marks Single Or Paired AKs, ...
Medicine Products: