Navigation Links
UNC neuroscientists discover new 'mini-neural computer' in the brain
Date:10/27/2013

n lab at the University of North Carolina. They used patch-clamp electrophysiology to attach a microscopic glass pipette electrode, filled with a physiological solution, to a neuronal dendrite in the brain of a mouse. The idea was to directly "listen" in on the electrical signaling process.

"Attaching the pipette to a dendrite is tremendously technically challenging," Smith said. "You can't approach the dendrite from any direction. And you can't see the dendrite. So you have to do this blind. It's like fishing if all you can see is the electrical trace of a fish." And you can't use bait. "You just go for it and see if you can hit a dendrite," he said. "Most of the time you can't."

But Smith built his own two-photon microscope system to make things easier.

Once the pipette was attached to a dendrite, Smith's team took electrical recordings from individual dendrites within the brains of anesthetized and awake mice. As the mice viewed visual stimuli on a computer screen, the researchers saw an unusual pattern of electrical signals bursts of spikes in the dendrite.

Smith's team then found that the dendritic spikes occurred selectively, depending on the visual stimulus, indicating that the dendrites processed information about what the animal was seeing.

To provide visual evidence of their finding, Smith's team filled neurons with calcium dye, which provided an optical readout of spiking. This revealed that dendrites fired spikes while other parts of the neuron did not, meaning that the spikes were the result of local processing within the dendrites.

Study co-author Tiago Branco, PhD, created a biophysical, mathematical model of neurons and found that known mechanisms could support the dendritic spiking recorded electrically, further validating the interpretation of the data.

"All the data pointed to the same conclusion," Smith said. "The dendrites are not passive integrators of sensory-driven input; the
'/>"/>

Contact: Mark Derewicz
mark.derewicz@unch.unc.edu
919-923-0959
University of North Carolina Health Care
Source:Eurekalert  

Page: 1 2 3

Related medicine news :

1. Johns Hopkins neuroscientists win National Academy of Science Awards
2. Neuroscientists find excessive protein synthesis linked to autistic-like behaviors
3. John Templeton Foundation grant supports Princeton neuroscientists to study cognitive control
4. Discover Step-By-Step Plans On How To Learn French Fast With The “Rocket French Premium” Program – Vkoolelite
5. Discover How to Determine Baby Gender With the “Prince Or Princess” Book – Vkoolelite
6. Biosimulation Market (Drug Discovery & Development) Worth $1.2 Billion by 2017 - New Report by MarketsandMarkets
7. Tear Film Evaporation Begins at Birth Water and Health Researcher Discovers
8. New Case Management Order in New Jersey DePuy ASR Recall Litigation Extends Discovery to June 2014, More than 650 Metal Hip Lawsuits Filed in Consolidated Proceeding
9. Discover 13 Natural Tips for Whitening Skin – V kool
10. The Producers of the In View Series Announce Upcoming Airing on the Discovery Channel
11. Ethicon Transvaginal Mesh Lawsuits Move Forward, With Scheduling of Discovery Conferences in Federal Vaginal Mesh Litigation, Bernstein Liebhard LLP Reports
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
UNC neuroscientists discover new 'mini-neural computer' in the brain
(Date:7/24/2014)... 2014 The report, “Content Delivery ... market into various sub-segments with an in-depth analysis ... drivers and restraints for this market with insights ... market data tables and 36 figures spread through ... Networks (CDN) Market” at http://www.marketsandmarkets.com/Market-Reports/content-delivery-networks-cdn-market-657.html . ...
(Date:7/24/2014)... By Amy Norton HealthDay ... stereotype of the sex-crazed teenage boy may be dead wrong, according ... from romantic relationships. In interviews with 33 boys between the ... wanted a relationship with a girl for the closeness and trust. ... "main goal" in starting a relationship with a girl. "In ...
(Date:7/24/2014)... Pools and beaches are the place to be ... especially for small children, so Amica Insurance is ... the Centers for Disease Control and Prevention, children between the ... water-related injuries and deaths. It’s important to know the best ... is offering the following tips from the American Red Cross:, ...
(Date:7/24/2014)... 24, 2014 (HealthDay News) -- Drinking caffeine may worsen ... two-thirds of women as they go through menopause, new ... our study suggests that limiting caffeine intake may be ... flashes and night sweats," said researcher Dr. Stephanie Faubion, ... Clinic in Rochester, Minn. But caffeine -- a ...
(Date:7/24/2014)... Horizon BCBSNJ’s second annual “Back to the Boardwalk” ... week in a beautiful Lavallette shore house, is accepting ... chance to win a week’s vacation at the Jersey ... residents, 25 or older.* Residents can enter by visiting ... , “A family vacation at the Jersey shore is ...
Breaking Medicine News(10 mins):Health News:CDN Market by Delivery Technologies & Solutions Expected to Reach $12.16 Billion by 2019 - New Report by MarketsandMarkets 2Health News:CDN Market by Delivery Technologies & Solutions Expected to Reach $12.16 Billion by 2019 - New Report by MarketsandMarkets 3Health News:CDN Market by Delivery Technologies & Solutions Expected to Reach $12.16 Billion by 2019 - New Report by MarketsandMarkets 4Health News:Teenage Boys Want Intimacy, Not Just Sex, Survey Finds 2Health News:Teenage Boys Want Intimacy, Not Just Sex, Survey Finds 3Health News:Keep Kids Safe in the Water with 5 Tips from Amica 2Health News:Is Coffee Aggravating Your Hot Flashes? 2Health News:(Beach) Sands of Time Running out to Enter Horizon Blue Cross Blue Shield of New Jersey’s 2014 “Back to the Boardwalk” Sweepstakes 2
... One of Brazil,s,leading distributors of pharmaceutical products, Profarma Distribuidora ... just announced its results for the first quarter of ... -- Growth of 26.5% in consolidated Gross Revenue when ... of the previous year, reaching R$ 702.6 million., ...
... and Strong Gross Margins ... Year-Over-Year - Key Internal Promotions, New Senior Director of ... Resignation of There du Pont Announced, ... leading online provider of health, beauty, vision, and,pharmacy products, today announced its ...
... National Alliance on,Mental Illness (NAMI) is honoring 30 ... the American Psychiatric Association (APA) this,week., "We ... states, who are stars,within the nation,s mental healthcare ... "They each have shown an exemplary,commitment to treatment ...
... Healthcare Realty,Trust Incorporated (NYSE: HR ) today announced ... for the first quarter of 2008 totaled $55.0,million, compared ... for the first quarter of 2008 totaled $5.7 million,compared ... first quarter of 2007, the Company recorded a $30.4 ...
... ,fever phobia, study finds , , MONDAY, May 5 (HealthDay News) ... and overtreat mild cases, a Johns Hopkins Children,s Center study ... how they view and treat the fever, the researchers added. ... when a child has a fever and to want to ...
... But the vast majority of adoptees are ,doing fine, researcher ... proportion of adopted American teens appear to be at heightened ... counterparts. , But that risk is moderate, emphasized the authors ... of Pediatrics & Adolescent Medicine . , "Most adoptees ...
Cached Medicine News:Health News:drugstore.com inc. Reports Results for the First Quarter of 2008 2Health News:drugstore.com inc. Reports Results for the First Quarter of 2008 3Health News:drugstore.com inc. Reports Results for the First Quarter of 2008 4Health News:drugstore.com inc. Reports Results for the First Quarter of 2008 5Health News:drugstore.com inc. Reports Results for the First Quarter of 2008 6Health News:drugstore.com inc. Reports Results for the First Quarter of 2008 7Health News:drugstore.com inc. Reports Results for the First Quarter of 2008 8Health News:drugstore.com inc. Reports Results for the First Quarter of 2008 9Health News:drugstore.com inc. Reports Results for the First Quarter of 2008 10Health News:drugstore.com inc. Reports Results for the First Quarter of 2008 11Health News:drugstore.com inc. Reports Results for the First Quarter of 2008 12Health News:drugstore.com inc. Reports Results for the First Quarter of 2008 13Health News:drugstore.com inc. Reports Results for the First Quarter of 2008 14Health News:drugstore.com inc. Reports Results for the First Quarter of 2008 15Health News:drugstore.com inc. Reports Results for the First Quarter of 2008 16Health News:drugstore.com inc. Reports Results for the First Quarter of 2008 17Health News:NAMI Honors Exemplary Psychiatrists: 30 Doctors From 21 States 2Health News:Healthcare Realty Trust Announces First Quarter Results 2Health News:Healthcare Realty Trust Announces First Quarter Results 3Health News:Healthcare Realty Trust Announces First Quarter Results 4Health News:Healthcare Realty Trust Announces First Quarter Results 5Health News:Healthcare Realty Trust Announces First Quarter Results 6Health News:Healthcare Realty Trust Announces First Quarter Results 7Health News:Healthcare Realty Trust Announces First Quarter Results 8Health News:Ethnicity Plays Role in Parents' Treatment of Childhood Fever 2Health News:Adopted Children at Slightly Higher Mental Health Risk 2Health News:Adopted Children at Slightly Higher Mental Health Risk 3
(Date:7/24/2014)... OAKS, Calif. , July 24, 2014 Amgen ... report its second quarter financial results on Tuesday, July 29, ... announcement will be followed by a conference call with the ... from Amgen will be Robert A. Bradway , chairman ... management team. Live audio of the conference call ...
(Date:7/24/2014)... Inc. (NYSE MKT: IG), a New Jersey based specialty generic ... the second quarter ended June 30, 2014. Second ... million in the second quarter of 2014, an increase of ... revenues of $13.3 million for the six months ended June ... in 2013 , Total revenues generated from the sale ...
(Date:7/24/2014)... 2014  Alimera Sciences, Inc. (NASDAQ: ALIM ... research, development and commercialization of prescription ophthalmic pharmaceuticals, today ... fiscal year 2014 financial results after the market close ... will follow on the same day at 4:30 p.m. ... hosted by Dan Myers , President and Chief ...
Breaking Medicine Technology:Amgen Announces Webcast of 2014 Second Quarter Financial Results 2IGI Laboratories Announces Second Quarter 2014 Results 2IGI Laboratories Announces Second Quarter 2014 Results 3IGI Laboratories Announces Second Quarter 2014 Results 4IGI Laboratories Announces Second Quarter 2014 Results 5IGI Laboratories Announces Second Quarter 2014 Results 6IGI Laboratories Announces Second Quarter 2014 Results 7Alimera Sciences To Release Second Quarter 2014 Results 2
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: