Navigation Links
UNC neuroscientists discover new 'mini-neural computer' in the brain
Date:10/27/2013

n lab at the University of North Carolina. They used patch-clamp electrophysiology to attach a microscopic glass pipette electrode, filled with a physiological solution, to a neuronal dendrite in the brain of a mouse. The idea was to directly "listen" in on the electrical signaling process.

"Attaching the pipette to a dendrite is tremendously technically challenging," Smith said. "You can't approach the dendrite from any direction. And you can't see the dendrite. So you have to do this blind. It's like fishing if all you can see is the electrical trace of a fish." And you can't use bait. "You just go for it and see if you can hit a dendrite," he said. "Most of the time you can't."

But Smith built his own two-photon microscope system to make things easier.

Once the pipette was attached to a dendrite, Smith's team took electrical recordings from individual dendrites within the brains of anesthetized and awake mice. As the mice viewed visual stimuli on a computer screen, the researchers saw an unusual pattern of electrical signals bursts of spikes in the dendrite.

Smith's team then found that the dendritic spikes occurred selectively, depending on the visual stimulus, indicating that the dendrites processed information about what the animal was seeing.

To provide visual evidence of their finding, Smith's team filled neurons with calcium dye, which provided an optical readout of spiking. This revealed that dendrites fired spikes while other parts of the neuron did not, meaning that the spikes were the result of local processing within the dendrites.

Study co-author Tiago Branco, PhD, created a biophysical, mathematical model of neurons and found that known mechanisms could support the dendritic spiking recorded electrically, further validating the interpretation of the data.

"All the data pointed to the same conclusion," Smith said. "The dendrites are not passive integrators of sensory-driven input; the
'/>"/>

Contact: Mark Derewicz
mark.derewicz@unch.unc.edu
919-923-0959
University of North Carolina Health Care
Source:Eurekalert  

Page: 1 2 3

Related medicine news :

1. Johns Hopkins neuroscientists win National Academy of Science Awards
2. Neuroscientists find excessive protein synthesis linked to autistic-like behaviors
3. John Templeton Foundation grant supports Princeton neuroscientists to study cognitive control
4. Discover Step-By-Step Plans On How To Learn French Fast With The “Rocket French Premium” Program – Vkoolelite
5. Discover How to Determine Baby Gender With the “Prince Or Princess” Book – Vkoolelite
6. Biosimulation Market (Drug Discovery & Development) Worth $1.2 Billion by 2017 - New Report by MarketsandMarkets
7. Tear Film Evaporation Begins at Birth Water and Health Researcher Discovers
8. New Case Management Order in New Jersey DePuy ASR Recall Litigation Extends Discovery to June 2014, More than 650 Metal Hip Lawsuits Filed in Consolidated Proceeding
9. Discover 13 Natural Tips for Whitening Skin – V kool
10. The Producers of the In View Series Announce Upcoming Airing on the Discovery Channel
11. Ethicon Transvaginal Mesh Lawsuits Move Forward, With Scheduling of Discovery Conferences in Federal Vaginal Mesh Litigation, Bernstein Liebhard LLP Reports
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
UNC neuroscientists discover new 'mini-neural computer' in the brain
(Date:5/22/2015)... Mountain Point Medical Center, a campus of Jordan Valley Medical ... 29, 2015 at 11 a.m., followed by a community celebration ... set to officially open on June 1, 2015, is located ... “The opening of Mountain Point Medical Center is an exciting ... Kent Loosle, CEO of Mountain Point Medical Center. “Mountain Point ...
(Date:5/22/2015)... NS (PRWEB) May 22, 2015 Following ... a sale agreement with US-based health brand Nature’s Way, ... Skin brand. Retention of Ascenta Skin is an integral ... is excited about this opportunity to further develop Ascenta ... , Ascenta Skin is a breakthrough, anti-aging skincare ...
(Date:5/22/2015)... Island, NY (PRWEB) May 22, 2015 ... announces that June 17, 2015, the Annual One Day ... place. Since 2007, Hands On HCMT offers drastically reduced certificates ... therapists and estheticians have enough sessions, through what used to ... it is wonderful for the community as well. This once ...
(Date:5/22/2015)... 22, 2015 Carnegie Science Center ... announced a new partnership to develop BodyTech, a dynamic, ... The initiative includes a new exhibit at the Science ... theater, and a new traveling science show, Anatomy Adventure, ... 2015. , Designed to explore a wide range ...
(Date:5/22/2015)... According to a new Aegis Living Study ... as likely to worry about what will happen to their ... Boomers, 69% Silent Generation), which may help explain why nearly ... aging, particularly Millennials (47%), Gen X’ers (51%), and Boomers (43%). ... 2015 among more than 2,000 U.S. adults ages 18+. ...
Breaking Medicine News(10 mins):Health News:Mountain Point Medical Center, a Campus of Jordan Valley Medical Center, Hosts Ribbon Cutting Ceremony and Community Celebration on Friday, May 29, 2015 2Health News:Ascenta Skin President Announces Plans to Grow Brand 2Health News:Hands On HealthCare Massage Therapy & Wellness Day Spa Announces Their Eighth Annual One Day Sale on Gift Certificates Will Take Place on June 17, 2015 2Health News:Hands On HealthCare Massage Therapy & Wellness Day Spa Announces Their Eighth Annual One Day Sale on Gift Certificates Will Take Place on June 17, 2015 3Health News:Carnegie Science Center, Allegheny Health Network Partner to Create BodyTech 2Health News:Carnegie Science Center, Allegheny Health Network Partner to Create BodyTech 3Health News:Carnegie Science Center, Allegheny Health Network Partner to Create BodyTech 4Health News:New Study Reveals America’s Fear of Aging 2Health News:New Study Reveals America’s Fear of Aging 3
... dangerous characteristics of cancer is its ability to metastasize, or ... major need for better tests to detect cells that break ... the body. Effective identification of these cells, referred to ... improve quality of life for many cancer patients. A commentary ...
... 16, 2010 The AIUM is pleased to ... AIUM to endorse the recent AIUM Training Guidelines ... guidelines allow for a several practitioners, including physicians, ... ultrasound examinations, marking significant promise for the future ...
... ... Healthcare, 89 percent of physicians agree that patients receiving negligent treatment deserve fair compensation. ... Alpharetta, GA (Vocus) March 16, ... of physicians agree that patients receiving negligent treatment deserve fair compensation. , , , , ...
... Many with severe peripheral arterial disease can avoid amputation, ... When angioplasty fails, patients with severe peripheral arterial disease ... placed in the blocked artery below the knee might ... limb ischemia, the most severe form of peripheral arterial ...
... taking Plavix before surgery died soon after than those ... (HealthDay News) -- In a trial comparing two anti-clotting ... less likely to die than those given Plavix, researchers ... forming clots, but Plavix, the more popular drug, has ...
... President and CEO Dr. Richard Merkin , was featured on several segments throughout the day on Fox National News and Fox Business Channel discussing current healthcare payment structures ... ... ... ...
Cached Medicine News:Health News:Revisiting the need to detect circulating tumor cells 2Health News:Unprecedented AIUM training guidelines speak to future of musculoskeletal ultrasound 2Health News:Recent Survey Reveals That Physicians Overwhelmingly Support Patient Compensation When Harmed 2Health News:Recent Survey Reveals That Physicians Overwhelmingly Support Patient Compensation When Harmed 3Health News:Stenting May Save Legs 2Health News:Stenting May Save Legs 3Health News:Newer Blood Thinner Beats Plavix for Bypass Patients 2Health News:Newer Blood Thinner Beats Plavix for Bypass Patients 3Health News:Lakeside Medical Group, Heritage Provider Network, CEO Dr. Richard Merkin, Featured on Several Segments of Fox National News and Fox Business Channel on Current Healthcare Payment Structures to Physicians 2Health News:Lakeside Medical Group, Heritage Provider Network, CEO Dr. Richard Merkin, Featured on Several Segments of Fox National News and Fox Business Channel on Current Healthcare Payment Structures to Physicians 3
(Date:5/21/2015)... 21, 2015 Research ... the addition of the "Arthroscopy Devices ... ,     (Logo: http://photos.prnewswire.com/prnh/20130307/600769) , ,The purpose of ... the world market for Arthroscopy Devices. The ... impacting the market for these products. , ...
(Date:5/21/2015)... 2015  Cardica, Inc. (Nasdaq: CRDC ) today announced ... , the company,s vice president of operations, was granted an ... at a per share exercise price of $0.43, the closing ... granted pursuant to Cardica, Inc.,s Inducement Plan, which was approved ... Rule 5653(c)(4) of the Nasdaq Global Market for equity grants ...
(Date:5/21/2015)... May 21, 2015 The Pharmaceutical Care ... the Medicare Part D offsets included in the ... "If the 21st Century Cures initiative can ... premier health program – Medicare – then its ... down the road. "Leveraging payments to ...
Breaking Medicine Technology:Analysing Arthroscopy Devices Markets Worldwide 2014-2020 2Analysing Arthroscopy Devices Markets Worldwide 2014-2020 3Cardica Announces New Employment Inducement Grant 2
... 22, 2011 Prasco Laboratories, the Authorized Generics company, ... Shionogi Inc . Under the terms of the ... Nitrofurantoin Oral Suspension, the Authorized Generic version of Furadantin® Oral ... U.S. under the Prasco label. "Prasco is ...
... ("MGT", "we", or "the Company") (AMEX: MGT ), a ... following update on recent developments at the Company and its majority-owned ... a summary of its recently filed financial results (via SEC Form ... 2011. Highlights: On ...
Cached Medicine Technology:Prasco® Launches Authorized Generic with Shionogi Inc. 2MGT Capital Investments, Inc. Provides Update on Recent Developments 2MGT Capital Investments, Inc. Provides Update on Recent Developments 3MGT Capital Investments, Inc. Provides Update on Recent Developments 4MGT Capital Investments, Inc. Provides Update on Recent Developments 5MGT Capital Investments, Inc. Provides Update on Recent Developments 6
... Post Operative Pin® Knee Brace (DxHDDLP) has a ... drop lock lever and laminate liner. The precision ... brace from migrating on the leg during ambulation. ... that controls flexion and extension in 5° increments ...
... Neuroprene™ soft supports are a convenient, ... proprioceptive taping for common orthopedic conditions/instabilities. ... provide specific compression and lateral to ... (proprioceptors) in the skin and soft ...
... The Drytex Adjustable Patella Donut ... a unique nylon core and polyester ... airflow. A trimable full-circumference donut provides ... who have neoprene based allergies or ...
... for total knees, meniscus repairs, regenerative chondroplasty, ... TROM gives easy-to-use range of motion control ... Rehab TROM can be used as a ... purchased separately be used with the TROM ...
Medicine Products: