Navigation Links
UCLA scientist uncovers biological clock able to measure age of most human tissues
Date:10/20/2013

"It's surprising that one could develop a clock that reliably keeps time across the human anatomy," he admitted. "My approach really compared apples and oranges, or in this case, very different parts of the body: the brain, heart, lungs, liver, kidney and cartilage."

While most samples' biological ages matched their chronological ages, others diverged significantly. For example, Horvath discovered that a woman's breast tissue ages faster than the rest of her body.

"Healthy breast tissue is about two to three years older than the rest of a woman's body," said Horvath. "If a woman has breast cancer, the healthy tissue next to the tumor is an average of 12 years older than the rest of her body."

The results may explain why breast cancer is the most common cancer in women. Given that the clock ranked tumor tissue an average of 36 years older than healthy tissue, it could also explain why age is a major risk factor for many cancers in both genders.

Horvath next looked at pluripotent stem cells, adult cells that have been reprogrammed to an embryonic stem celllike state, enabling them to form any type of cell in the body and continue dividing indefinitely.

"My research shows that all stem cells are newborns," he said. "More importantly, the process of transforming a person's cells into pluripotent stem cells resets the cells' clock to zero."

In principle, the discovery proves that scientists can rewind the body's biological clock and restore it to zero.

"The big question is whether the biological clock controls a process that leads to aging," Horvath said. "If so, the clock will become an important biomarker for studying new therapeutic approaches to keeping us young."

Finally, Horvath discovered that the clock's rate speeds up or slows down depending on a person's age.

"The clock's ticking rate isn't constant," he explained. "It ticks much faster when we're born and growing
'/>"/>

Contact: Elaine Schmidt
eschmidt@mednet.ucla.edu
310-794-2272
University of California - Los Angeles Health Sciences
Source:Eurekalert  

Page: 1 2 3

Related medicine news :

1. Scientists solving the mystery of human consciousness
2. Scientists uncover multiple faces of deadly breast cancer
3. Scientist awarded $1 million grant to develop tools for hepatitis C treatment discovery
4. Scientists identify major source of cells defense against oxidative stress
5. Scientists tailor cell surface targeting system to hit organelle ZIP codes
6. Scientists rewrite rulebook on breast cancer in landmark global study
7. Kessler Foundation scientist awarded $554,000 for multiple sclerosis employment research
8. Warwick scientists uncover how checkpoint proteins bind chromosomes
9. NIH scientists link quickly spreading gene to Asian MRSA epidemic
10. Joslin scientists identify important mechanism that affects the aging process
11. Scripps Research scientists show how memory B cells stay in class to fight different infections
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
UCLA scientist uncovers biological clock able to measure age of most human tissues
(Date:9/2/2014)... A New York City based company is ... yet revolutionary, product that will have far-reaching, ... care costs for Americans. , REMIND-A-CAP™ is ... control in the user's hands. It's a simple device ... date of intake by simply turning a knob. No ...
(Date:9/2/2014)... Welcome to Arthritis Awareness Month ... Canadians living with the disease, The Arthritis Society is ... series featuring well-known Canadians from different walks of life ... Lloyd Robertson , veteran news anchor , ... ,      Amy Cotton , two-time Olympic wrestler ...
(Date:9/2/2014)... A little white pill may help scientists learn why ... their peers, even if their lungs are relatively healthy. ... marketed as Revatio to treat pulmonary hypertension and Viagra ... of over-the-counter antioxidants will help them identify the root ... for these patients. , "We want to understand ...
(Date:9/2/2014)... Cardiology Congress in Barcelona shows that having a family ... motivate people to follow healthy lifestyles. , Researchers ... online tool that engages people presenting their personal CVD ... the hypothesis that those who have a family history ... and blood pressure checks and be motivated to adopt ...
(Date:9/2/2014)... be a new salve to dominate medicine cabinets of the ... Salamanders may not be the cuddliest of animals, but they ... damaged body parts. Now, a new report published in the ... , identifies a small protein (called a "peptide") from the ... the secret of this amazing wound healing trick in humans. ...
Breaking Medicine News(10 mins):Health News:REMIND-A-CAP™ , A New York City Based Company Invents Groundbreaking Prescription Cap to Curb Non-Adherence 2Health News:‘Voices of Arthritis’ Launches Awareness Month 2Health News:‘Voices of Arthritis’ Launches Awareness Month 3Health News:Drug that improves blood flow may help find cause of exercise intolerance in cystic fibrosis 2Health News:Drug that improves blood flow may help find cause of exercise intolerance in cystic fibrosis 3Health News:Drug that improves blood flow may help find cause of exercise intolerance in cystic fibrosis 4Health News:Family history of cardiovascular disease is not enough to motivate people to follow healthy lifestyle 2Health News:Salamander skin peptide promotes quick and effective wound healing in mice 2
... finds chlorthalidone most likely to prevent heart failure, ... Tried-and-true diuretics maintain their status as the best ... high blood pressure, new research concludes. , The ... a calcium channel blocker, an ACE inhibitor and ...
... Nov. 18 The U.S. Agency for International Development (USAID) ... up with Chicago Cubs Charities Nov. 17 to donate $100,000 ... Basic School and Education Center for Integrated Health (CESI). , ... and...Loyola and Creighton (universities) to help children and their families ...
... Release Statewide Data , HARRISBURG, Pa., Nov. 18 Pennsylvania is ... and adults living with autism, according to the Pennsylvania Autism Census ... , "With the release of this report, Pennsylvania becomes the first ... to meet the needs of the rapidly growing population of children ...
... The National Patient Safety Foundation (NPSF) today issued the following position ... The National Patient Safety Foundation recognizes vaccine-preventable, ... and supports mandatory, influenza vaccination of ... patients, health care workers, and the community. NPSF appreciates, ...
... Nov. 18 Hospice workers have seen patients hang onto ... from the Frances Payne Bolton School of Nursing and the ... will study what drives the dying to resolve unfinished business. ... Prince-Paul from nursing and Julie Exline from arts and sciences ...
... at Mount Sinai School of Medicine set out to ... years: How do dietary restrictionand the reverse, overconsumptionproduce protective ... in a two-part study led by Charles Mobbs, PhD, ... at Mount Sinai School of Medicine, published in the ...
Cached Medicine News:Health News:Diuretics Still Best Treatment for High Blood Pressure 2Health News:USAID, Cubs Charities Make a Grand Slam for Health and Basic Education 2Health News:PA Governor Rendell: New Report Shows Demand for Autism Services will Continue to Rise 2Health News:National Patient Safety Foundation Supports Mandatory Flu Vaccinations for Healthcare Workers 2Health News:National Patient Safety Foundation Supports Mandatory Flu Vaccinations for Healthcare Workers 3Health News:Research Collaboration Focuses on Unfinished Business at the End of Life 2Health News:Scientists find molecular trigger that helps prevent aging and disease 2Health News:Scientists find molecular trigger that helps prevent aging and disease 3
(Date:9/2/2014)... September 2, 2014 According ... Market Research "Latin America Home Healthcare Market (By ... Healthcare Devices, Mobility Assist Devices and Medical Supplies; ... Infusion Therapy and Unskilled Home Healthcare Services) - ... 2014 - 2020" the Latin American Home Healthcare ...
(Date:9/2/2014)... Calif. , Sept. 2, 2014   Santa ... now offering a special promotion for Invisalign. Invisalign is ... brackets and wires. It is often the orthodontic treatment ... the convenience and aesthetics of it. For a limited ... is a significant savings from the usual cost. This ...
(Date:9/2/2014)... España, September 2, 2014 ... fibrilación atrial muestran agentes antitrombóticos no utilizados óptimamente ... -- Las presentaciones de GARFIELD-AF en el ... tratamiento y los resultados de pacientes en riesgo ... --    Los datos de casi ...
Breaking Medicine Technology:Home Healthcare Market in Latin America Expected to Reach USD 17.5 Billion in 2020: Transparency Market Research 2Home Healthcare Market in Latin America Expected to Reach USD 17.5 Billion in 2020: Transparency Market Research 3Home Healthcare Market in Latin America Expected to Reach USD 17.5 Billion in 2020: Transparency Market Research 4Home Healthcare Market in Latin America Expected to Reach USD 17.5 Billion in 2020: Transparency Market Research 5Home Healthcare Market in Latin America Expected to Reach USD 17.5 Billion in 2020: Transparency Market Research 6Santa Clara Cosmetic Dentist, Dr. Alan Frame, is Now Offering a Special on Invisalign 2Los datos sobre fibrilación atrial muestran agentes antitrombóticos no usados óptimamente para prevenir la apoplejía 2Los datos sobre fibrilación atrial muestran agentes antitrombóticos no usados óptimamente para prevenir la apoplejía 3Los datos sobre fibrilación atrial muestran agentes antitrombóticos no usados óptimamente para prevenir la apoplejía 4Los datos sobre fibrilación atrial muestran agentes antitrombóticos no usados óptimamente para prevenir la apoplejía 5Los datos sobre fibrilación atrial muestran agentes antitrombóticos no usados óptimamente para prevenir la apoplejía 6Los datos sobre fibrilación atrial muestran agentes antitrombóticos no usados óptimamente para prevenir la apoplejía 7Los datos sobre fibrilación atrial muestran agentes antitrombóticos no usados óptimamente para prevenir la apoplejía 8Los datos sobre fibrilación atrial muestran agentes antitrombóticos no usados óptimamente para prevenir la apoplejía 9Los datos sobre fibrilación atrial muestran agentes antitrombóticos no usados óptimamente para prevenir la apoplejía 10Los datos sobre fibrilación atrial muestran agentes antitrombóticos no usados óptimamente para prevenir la apoplejía 11
... , WASHINGTON, Dec. 14 ... counsel on global and domestic communications and issues management, ... PositiveID Corporation (Nasdaq: PSID ) to serve as ... will conduct media relations for PositiveID,s corporate communications and ...
... , NEW HAVEN, Conn., ,Dec. 14 /PRNewswire-FirstCall/ ... today announced that it had received a complete response ... related to its New Drug Application ("NDA") for Onrigin(TM) ... indicates that the FDA cannot approve the Company,s NDA ...
Cached Medicine Technology:Gibraltar Associates Named Agency of Record for Health Information and Diagnostic Provider PositiveID Corporation 2Vion Pharmaceuticals Receives Complete Response Letter for Onrigin(TM) From The U.S. Food And Drug Administration 2Vion Pharmaceuticals Receives Complete Response Letter for Onrigin(TM) From The U.S. Food And Drug Administration 3
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: