Navigation Links
UCLA scientist uncovers biological clock able to measure age of most human tissues
Date:10/20/2013

"It's surprising that one could develop a clock that reliably keeps time across the human anatomy," he admitted. "My approach really compared apples and oranges, or in this case, very different parts of the body: the brain, heart, lungs, liver, kidney and cartilage."

While most samples' biological ages matched their chronological ages, others diverged significantly. For example, Horvath discovered that a woman's breast tissue ages faster than the rest of her body.

"Healthy breast tissue is about two to three years older than the rest of a woman's body," said Horvath. "If a woman has breast cancer, the healthy tissue next to the tumor is an average of 12 years older than the rest of her body."

The results may explain why breast cancer is the most common cancer in women. Given that the clock ranked tumor tissue an average of 36 years older than healthy tissue, it could also explain why age is a major risk factor for many cancers in both genders.

Horvath next looked at pluripotent stem cells, adult cells that have been reprogrammed to an embryonic stem celllike state, enabling them to form any type of cell in the body and continue dividing indefinitely.

"My research shows that all stem cells are newborns," he said. "More importantly, the process of transforming a person's cells into pluripotent stem cells resets the cells' clock to zero."

In principle, the discovery proves that scientists can rewind the body's biological clock and restore it to zero.

"The big question is whether the biological clock controls a process that leads to aging," Horvath said. "If so, the clock will become an important biomarker for studying new therapeutic approaches to keeping us young."

Finally, Horvath discovered that the clock's rate speeds up or slows down depending on a person's age.

"The clock's ticking rate isn't constant," he explained. "It ticks much faster when we're born and growing
'/>"/>

Contact: Elaine Schmidt
eschmidt@mednet.ucla.edu
310-794-2272
University of California - Los Angeles Health Sciences
Source:Eurekalert  

Page: 1 2 3

Related medicine news :

1. Scientists solving the mystery of human consciousness
2. Scientists uncover multiple faces of deadly breast cancer
3. Scientist awarded $1 million grant to develop tools for hepatitis C treatment discovery
4. Scientists identify major source of cells defense against oxidative stress
5. Scientists tailor cell surface targeting system to hit organelle ZIP codes
6. Scientists rewrite rulebook on breast cancer in landmark global study
7. Kessler Foundation scientist awarded $554,000 for multiple sclerosis employment research
8. Warwick scientists uncover how checkpoint proteins bind chromosomes
9. NIH scientists link quickly spreading gene to Asian MRSA epidemic
10. Joslin scientists identify important mechanism that affects the aging process
11. Scripps Research scientists show how memory B cells stay in class to fight different infections
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
UCLA scientist uncovers biological clock able to measure age of most human tissues
(Date:11/28/2014)... An inventor and dental assistant from Kent, Wash., ... and it was almost impossible to reach. "This gave me ... , The patent-pending Access Light allows for easier use of ... the mouth, as well as avoids harm to the lips, ... use and clean, it also helps prevent cross-contamination. , The ...
(Date:11/28/2014)... (PRWEB) November 28, 2014 A newly ... provides an overview of the influenza virus that will soon ... season. , The article begins with a brief explanation ... its symptoms. It reminds families that children under the age ... suffering from chronic diseases, such as heart and lung diseases, ...
(Date:11/28/2014)... "Most of my life, I have suffered from ... an inventor from Findlay, Ohio. "I thought that there had ... foot, which inspired me to invent this accessory." , She ... to support an injured foot. The sling makes it easier ... for crutches. The design redistributes weight so that the individual ...
(Date:11/28/2014)... TN (PRWEB) November 28, 2014 ARTAS ... Tennessee for the first time. PAI Medical Group hair ... will be performing a robotic hair transplant procedure in ... 9:00 A.M. , The first in Tennessee and one ... Medical Group now offers ARTAS robotic hair transplantation. Patients ...
(Date:11/28/2014)... Nipomo Family Dentistry , founded ... opened its doors at 195 N. Thompson St., Suite ... care like teeth cleanings, oral exams, fillings, implants and ... whitening (and Kor whitening), laser whitening, gum tissue treatment, ... Dentistry’s five-person team also takes a philanthropic approach to ...
Breaking Medicine News(10 mins):Health News:How Flu Vaccines Can Impact Families Is Discussed in New Article from Community Health Center of Snohomish County 2Health News:First in Tennessee - PAI Medical Group Announces ARTAS - The World’s Most Advanced Medical Robot Used for Hair Transplant Surgery 2Health News:Nipomo Family Dentistry Opens New Dental Office in Nipomo 2Health News:Nipomo Family Dentistry Opens New Dental Office in Nipomo 3
... choice of drug for patients suffering from prostate cancer may ... the Scottish Medicines Consortium (SMC) is of the view that ... much effect on prostate cancer making it an expensive not ... the drug feel that the drug had shown very good ...
... of the main causes of tooth loss worldwide and ... extractions (those with periodontal disease lost 2.8 teeth versus ... has now been found out from research that certain ... than others. ,The study analyzed the effects ...
... sinus tumors can be removed through the nose using endoscopy ... ,With this approach, doctors use tiny scopes and ... a device that pulverizes and suctions. At points where the ... and a diamond drill is used to eliminate tumor cells ...
... appears in the October issue of the journal ... early exposure to severe hypoglycemia during development negatively ... is a significant and relatively common complication of ... Repeated severe hypoglycemia has been reported to reduce ...
... Minister Anbumani Ramadoss has said that the government is very ... plans to take several steps to check female foeticide, which ... Ramadoss said that there were plans to set up surveillance ... practice that prevails on a large scale in the country. ...
... new research shows that in Children with neurological ... respiratory failure ,if they're hospitalized with influenza.// ... Journal of the American Medical Association, are based on ... influenza at The Children's Hospital of Philadelphia over four ...
Cached Medicine News:Health News:Nine Major Culprits For Tooth Loss Identified By Researchers 2Health News:Nine Major Culprits For Tooth Loss Identified By Researchers 3Health News:Novel Technique For Management Of Inverted Papilloma Of Frontal Sinus 2Health News:Severe Hypoglycemia And Spatial Memory In Children With Type 1 Diabetes 2
(Date:11/26/2014)... DUBLIN , Nov. 26, 2014  Perrigo Company ... leading global provider of "Quality Affordable Healthcare Products®," today ... offering relating to the sale of 6,809,210 ordinary shares ... including the full exercise of the option to purchase ... Morgan Securities LLC and Barclays Capital Inc., as representatives ...
(Date:11/26/2014)... , Nov. 26, 2014   Regulus Therapeutics Inc ... leading the discovery and development of innovative medicines targeting ... Ph.D., President and CEO of Regulus, will present a ... Jaffray Healthcare Conference at the New York Palace Hotel ... The presentation will be webcast at the time of ...
(Date:11/26/2014)... Scott Steiger lives in St. ... an engineer for the past 20 years, he,s traveled extensively and ... He,s been to six of the seven continents. Travel is a ... http://photos.prnewswire.com/prnh/20141126/161076 Photo - http://photos.prnewswire.com/prnh/20141126/161077 So ... pretty good idea of what,s required. His latest creation ...
Breaking Medicine Technology:Perrigo Company plc Announces The Closing Of Its Registered Public Offering Of Ordinary Shares 2Perrigo Company plc Announces The Closing Of Its Registered Public Offering Of Ordinary Shares 3Perrigo Company plc Announces The Closing Of Its Registered Public Offering Of Ordinary Shares 4Regulus to Present at the 26th Annual Piper Jaffray Healthcare Conference and Genetic Rx Conference 2Regulus to Present at the 26th Annual Piper Jaffray Healthcare Conference and Genetic Rx Conference 3Steiger Has Created the First Pill Case Specifically Designed For Travel 2
... by experts to be important for cervical cancer ... data from an,extended follow-up study show that GlaxoSmithKline ... generates sustained high levels of,neutralizing antibodies against the ... up to 6.4 years. This is the longest,duration ...
... American Society of Hypertension,s Twenty-Third ... Annual Scientific Meeting - A cumulative ... a regimen of BENICAR(R) (olmesartan medoxomil), and BENICAR HCT(R) (olmesartan ... normotension (< 120/80 mm Hg) (placebo:1.4%)., - Eight out of ...
Cached Medicine Technology:CERVARIX(R) Shown to Provide Longest Duration of Sustained Neutralizing Antibodies to Date 2CERVARIX(R) Shown to Provide Longest Duration of Sustained Neutralizing Antibodies to Date 3CERVARIX(R) Shown to Provide Longest Duration of Sustained Neutralizing Antibodies to Date 4CERVARIX(R) Shown to Provide Longest Duration of Sustained Neutralizing Antibodies to Date 5CERVARIX(R) Shown to Provide Longest Duration of Sustained Neutralizing Antibodies to Date 6New Data Shows 45 Percent of Patients with Stage 1 Hypertension Reached Normotension with BENICAR(R) and BENICAR HCT(R) 2New Data Shows 45 Percent of Patients with Stage 1 Hypertension Reached Normotension with BENICAR(R) and BENICAR HCT(R) 3New Data Shows 45 Percent of Patients with Stage 1 Hypertension Reached Normotension with BENICAR(R) and BENICAR HCT(R) 4New Data Shows 45 Percent of Patients with Stage 1 Hypertension Reached Normotension with BENICAR(R) and BENICAR HCT(R) 5New Data Shows 45 Percent of Patients with Stage 1 Hypertension Reached Normotension with BENICAR(R) and BENICAR HCT(R) 6New Data Shows 45 Percent of Patients with Stage 1 Hypertension Reached Normotension with BENICAR(R) and BENICAR HCT(R) 7
... WideBiter Punch series facilitates fast and effective ... smooth, anatomically shaped meniscal rim. The flat, ... to access even the tightest joint spaces. ... Inc., 20 years of engineering experience in ...
... fast and effective resection of meniscal tears ... rim. The flat, crescent-shaped tip has an ... tightest joint spaces. Made in the U.S. ... engineering experience in arthroscopy hand instrument design ...
... The WideBiter Punch series facilitates fast ... recreating a smooth, anatomically shaped meniscal rim. ... low profile to access even the tightest ... Arthrex California, Inc., 20 years of engineering ...
... The WideBiter Punch series facilitates fast ... recreating a smooth, anatomically shaped meniscal rim. ... low profile to access even the tightest ... Arthrex California, Inc., 20 years of engineering ...
Medicine Products: