Navigation Links
UCLA scientist uncovers biological clock able to measure age of most human tissues
Date:10/20/2013

"It's surprising that one could develop a clock that reliably keeps time across the human anatomy," he admitted. "My approach really compared apples and oranges, or in this case, very different parts of the body: the brain, heart, lungs, liver, kidney and cartilage."

While most samples' biological ages matched their chronological ages, others diverged significantly. For example, Horvath discovered that a woman's breast tissue ages faster than the rest of her body.

"Healthy breast tissue is about two to three years older than the rest of a woman's body," said Horvath. "If a woman has breast cancer, the healthy tissue next to the tumor is an average of 12 years older than the rest of her body."

The results may explain why breast cancer is the most common cancer in women. Given that the clock ranked tumor tissue an average of 36 years older than healthy tissue, it could also explain why age is a major risk factor for many cancers in both genders.

Horvath next looked at pluripotent stem cells, adult cells that have been reprogrammed to an embryonic stem celllike state, enabling them to form any type of cell in the body and continue dividing indefinitely.

"My research shows that all stem cells are newborns," he said. "More importantly, the process of transforming a person's cells into pluripotent stem cells resets the cells' clock to zero."

In principle, the discovery proves that scientists can rewind the body's biological clock and restore it to zero.

"The big question is whether the biological clock controls a process that leads to aging," Horvath said. "If so, the clock will become an important biomarker for studying new therapeutic approaches to keeping us young."

Finally, Horvath discovered that the clock's rate speeds up or slows down depending on a person's age.

"The clock's ticking rate isn't constant," he explained. "It ticks much faster when we're born and growing
'/>"/>

Contact: Elaine Schmidt
eschmidt@mednet.ucla.edu
310-794-2272
University of California - Los Angeles Health Sciences
Source:Eurekalert  

Page: 1 2 3

Related medicine news :

1. Scientists solving the mystery of human consciousness
2. Scientists uncover multiple faces of deadly breast cancer
3. Scientist awarded $1 million grant to develop tools for hepatitis C treatment discovery
4. Scientists identify major source of cells defense against oxidative stress
5. Scientists tailor cell surface targeting system to hit organelle ZIP codes
6. Scientists rewrite rulebook on breast cancer in landmark global study
7. Kessler Foundation scientist awarded $554,000 for multiple sclerosis employment research
8. Warwick scientists uncover how checkpoint proteins bind chromosomes
9. NIH scientists link quickly spreading gene to Asian MRSA epidemic
10. Joslin scientists identify important mechanism that affects the aging process
11. Scripps Research scientists show how memory B cells stay in class to fight different infections
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
UCLA scientist uncovers biological clock able to measure age of most human tissues
(Date:8/22/2014)... study finds a wide range of epigenetic changesalterations in ... environmental exposuresin children with Crohn,s disease (CD), reports ... Crohn,s & Colitis Foundation of America (CCFA). The ... a part of Wolters Kluwer Health . ... in several regions of the genome in children with CD, ...
(Date:8/22/2014)... Women treated for the cancer Hodgkin lymphoma will be ... after researchers estimated their risk of premature menopause with ... Journal of the National Cancer Institute , are ... women in England and Wales treated for the cancer ... Previous research has suggested that women with Hodgkin lymphoma ...
(Date:8/22/2014)... The New Jersey Institute for Food, Nutrition ... of New Jersey has joined forces with ChopChop ... young people about health and nutrition in a new ... organizations. , The partnership will encompass quarterly custom editions ... video communications. ChopChop Magazine features plenty of child-friendly ...
(Date:8/22/2014)... (PRWEB) August 22, 2014 Ticket Down ... in East Hartford, CT at Rentschler Field. There has never ... the United States than right now. After the strong showing at ... fans and the sport is being featured in large stadiums around ... an eight team tournament that featured some of the best club ...
(Date:8/22/2014)... Statesville, N.C. (PRWEB) August 22, 2014 ... the managed employee reward and recognition industry, has received ... With an extraordinary growth rate of 134%, TharpeRobbins remains ... companies in North America. TharpeRobbins was previously on the ... are honored to be included in this distinguished list ...
Breaking Medicine News(10 mins):Health News:Study shows epigenetic changes in children with Crohn's disease 2Health News:Scientists map risk of premature menopause after cancer treatment 2Health News:New Jersey Institute for Food, Nutrition & Health to Launch Innovative Partnership with Award-Winning Children’s Anti-Obesity Organization, ChopChop Kids 2Health News:New Jersey Institute for Food, Nutrition & Health to Launch Innovative Partnership with Award-Winning Children’s Anti-Obesity Organization, ChopChop Kids 3Health News:USA vs. Ecuador Tickets: Ticket Down Slashes USA (USMT) vs. Ecuador Tickets at Rentschler Field in East Hartford on Oct. 10th 2Health News:USA vs. Ecuador Tickets: Ticket Down Slashes USA (USMT) vs. Ecuador Tickets at Rentschler Field in East Hartford on Oct. 10th 3Health News:For The Fourth Time - TharpeRobbins Earns A Place On Prestigious Inc. Magazine 500|5000 List 2Health News:For The Fourth Time - TharpeRobbins Earns A Place On Prestigious Inc. Magazine 500|5000 List 3
... KUNMING, China, Sept. 13 /Xinhua-PRNewswire-FirstCall/ -- China,Shenghuo ... KUN ), which is engaged in ... nutritional supplement and cosmetic,products in the People,s ... the full-scale launch of its 12Ways(R) Chinese ...
... Sept. 13 Scimitar Equity Research, Inc.,(Scimitar) today ... Bulletin,Board: ABOS) entitled: "Enhancing the Recovery of Patients ... research review is,available on Scimitar,s website: http://www.scimitarequity.com ... Device The SEPET(TM) Liver Assist Device is ...
... correlation, with risk doubling as blood cells decline , ... declining blood platelet counts may be at increased risk ... behavioral and motor skill problems, researchers report. , Researchers ... Johns Hopkins University School of Medicine in Baltimore studied ...
... (Sept. 10, 2007) -- For high-blood-pressure patients, preventing or ... risk of heart failure. The study is published in ... by physician-scientists at NewYork-Presbyterian Hospital/Weill Cornell Medical Center in ... all high-blood-pressure patients, or 12 million Americans, have LVH ...
... Health Corp. is the Distributor of the Popular Dietary Supplement ... ... Health Corp. is proud to,announce its retail presence has expanded again ... and Sweet Bay,Supermarkets. LipidShield Plus is the popular NATURAL breakthrough ...
... Reports Solid Progress on Child Survival, NEW YORK, Sept. ... below 10 million per year to 9.7 million,down from almost ... an historic moment," said UNICEF Executive Director Ann M.,Veneman. "Now ... for the,achievement of the Millennium Development Goals." Among these ...
Cached Medicine News:Health News:China Shenghuo Pharmaceutical Holdings, Inc. Begins Full-Scale Launch of 12Ways(R) Chinese Herbal Skin Care Product Line 2Health News:China Shenghuo Pharmaceutical Holdings, Inc. Begins Full-Scale Launch of 12Ways(R) Chinese Herbal Skin Care Product Line 3Health News:China Shenghuo Pharmaceutical Holdings, Inc. Begins Full-Scale Launch of 12Ways(R) Chinese Herbal Skin Care Product Line 4Health News:Arbios Systems, Inc's Q2/07 Analyst Review Issued by Scimitar Equity Research, Inc. 2Health News:Falling Platelet Counts May Signal HIV-Linked Dementia 2Health News:Preventing or reducing enlarged heart decreases risk of heart failure 2Health News:New Health Corp. Announces the Addition of Hannaford Bros., Kash N Karry and Sweet Bay Supermarkets to its Retail Outlets 2Health News:Child Deaths Fall Below 10 Million For First Time 2Health News:Child Deaths Fall Below 10 Million For First Time 3Health News:Child Deaths Fall Below 10 Million For First Time 4
(Date:8/21/2014)...  Publicis Groupe customer engagement agency Rosetta ... Healthcare Industry Group Leader, has been featured in the ... inspiring people in the life-sciences industry. Those chosen for ... marketing, technology, creativity, strategy and medicine. ... in its leading Rosetta Consulting practice. In 2012, she ...
(Date:8/21/2014)... , Aug. 21, 2014 /PRNewswire-iReach/ -- Inc. ... Inc. for the third straight year, No. 349 ... an exclusive ranking of the nation,s fastest-growing private ... at the most important segment of the economy—America,s ... Dell, Domino,s Pizza, LinkedIn, Zillow, and many other ...
(Date:8/21/2014)... Aug. 21, 2014  Zacks.com announces the list of stocks ... Research analysts discuss the latest news and events impacting stocks ... include the Hewlett-Packard (NYSE: HPQ - Free Report ), IBM ... (NYSE: SB - Free Report ), GlaxoSmithKline plc (NYSE: ... (NYSE: FI - Free Report ). Today, ...
Breaking Medicine Technology:Shannon Hartley Shines in PharmaVOICE 100 2Carolina's HME Named for Third Straight Year to Inc. Magazine's List of America's Fastest-Growing Private Companies--the Inc. 5000 2Carolina's HME Named for Third Straight Year to Inc. Magazine's List of America's Fastest-Growing Private Companies--the Inc. 5000 3The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 2The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 3The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 4The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 5The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 6The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 7The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 8The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 9The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 10The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 11
... Misonix, Inc. (NASDAQ: MSON ), a ... innovative therapeutic ultrasonic products worldwide for wound debridement, ... other surgical and medical applications, announced its recent ... Advances in Skin and Wound Care held in ...
... GAITHERSBURG, Md., Nov. 1, 2011 /PRNewswire-iReach/ ... specialty pharmaceutical company focused exclusively in the HIV-1 ... DFH an exclusive research license with an option ... maturation inhibitor program.  Maturation inhibitors are a novel ...
Cached Medicine Technology:Misonix Exhibits at 26th Annual Clinical Symposium on Advances in Skin and Wound Care 2Misonix Exhibits at 26th Annual Clinical Symposium on Advances in Skin and Wound Care 3DFH Pharma Obtains Exclusive Rights to Second-Generation HIV Maturation Inhibitor Program 2DFH Pharma Obtains Exclusive Rights to Second-Generation HIV Maturation Inhibitor Program 3DFH Pharma Obtains Exclusive Rights to Second-Generation HIV Maturation Inhibitor Program 4
... Sterile Bad-Parker blades offer the ... stainless steel technology, plus the exclusive ... and strength. Brad-Parker brand producer offer ... handles and disposable scalpels. Every blade ...
BD Beaver implant blade, 5.1 mm, angled 45, bevel up. matte finish. Designed for widening the incision for lens implantation. Beaver implant blades put precision and control in your hands, sterile....
BD Beaver Meniscus blade, 7 mm flat (4/bx, 1 bx/ca), specially designed maximum leverage and visibility, cutting edge: 7 mm, sterile....
... fit standard trial frames. They are made of optical ... display box. There are two sets available providing a ... that is that a patient can wear the prism ... allow the patient to adapt to the use of ...
Medicine Products: