Navigation Links
UCLA scientist uncovers biological clock able to measure age of most human tissues
Date:10/20/2013

"It's surprising that one could develop a clock that reliably keeps time across the human anatomy," he admitted. "My approach really compared apples and oranges, or in this case, very different parts of the body: the brain, heart, lungs, liver, kidney and cartilage."

While most samples' biological ages matched their chronological ages, others diverged significantly. For example, Horvath discovered that a woman's breast tissue ages faster than the rest of her body.

"Healthy breast tissue is about two to three years older than the rest of a woman's body," said Horvath. "If a woman has breast cancer, the healthy tissue next to the tumor is an average of 12 years older than the rest of her body."

The results may explain why breast cancer is the most common cancer in women. Given that the clock ranked tumor tissue an average of 36 years older than healthy tissue, it could also explain why age is a major risk factor for many cancers in both genders.

Horvath next looked at pluripotent stem cells, adult cells that have been reprogrammed to an embryonic stem celllike state, enabling them to form any type of cell in the body and continue dividing indefinitely.

"My research shows that all stem cells are newborns," he said. "More importantly, the process of transforming a person's cells into pluripotent stem cells resets the cells' clock to zero."

In principle, the discovery proves that scientists can rewind the body's biological clock and restore it to zero.

"The big question is whether the biological clock controls a process that leads to aging," Horvath said. "If so, the clock will become an important biomarker for studying new therapeutic approaches to keeping us young."

Finally, Horvath discovered that the clock's rate speeds up or slows down depending on a person's age.

"The clock's ticking rate isn't constant," he explained. "It ticks much faster when we're born and growing
'/>"/>

Contact: Elaine Schmidt
eschmidt@mednet.ucla.edu
310-794-2272
University of California - Los Angeles Health Sciences
Source:Eurekalert  

Page: 1 2 3

Related medicine news :

1. Scientists solving the mystery of human consciousness
2. Scientists uncover multiple faces of deadly breast cancer
3. Scientist awarded $1 million grant to develop tools for hepatitis C treatment discovery
4. Scientists identify major source of cells defense against oxidative stress
5. Scientists tailor cell surface targeting system to hit organelle ZIP codes
6. Scientists rewrite rulebook on breast cancer in landmark global study
7. Kessler Foundation scientist awarded $554,000 for multiple sclerosis employment research
8. Warwick scientists uncover how checkpoint proteins bind chromosomes
9. NIH scientists link quickly spreading gene to Asian MRSA epidemic
10. Joslin scientists identify important mechanism that affects the aging process
11. Scripps Research scientists show how memory B cells stay in class to fight different infections
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
UCLA scientist uncovers biological clock able to measure age of most human tissues
(Date:9/1/2015)... ... 2015 , ... Virginia entrepreneur Marcella Ellis, CEO and founder ... firm’s success in the hair care and distribution industry through her combination of ... be providing “Look and learn” live demonstrations, as well as promoting her new ...
(Date:9/1/2015)... ... September 01, 2015 , ... OncLive® ... by U.S. News & World Report, to provide breaking news and information about ... marketing groups within OncLive, which provides oncologists resources and information?they need to deliver ...
(Date:9/1/2015)... PA (PRWEB) , ... September 01, 2015 , ... The ... 18 at The ACE Club and Green Valley Country Club in Lafayette Hill, PA. ... has raised more than $13.5 million for programs and services designed to support patients ...
(Date:9/1/2015)... Winston-Salem, NC (PRWEB) , ... September 01, 2015 , ... ... (Science, Technology, Engineering and Math) disciplines since its inception more than 35 years ago. ... and high-school students and their teachers - and, not just those intent on pursuing ...
(Date:9/1/2015)... ... September 01, 2015 , ... e-Spirit Inc., ... 5.2 of the FirstSpirit Content Management System with new capabilities and enhancements designed ... of FirstSpirit, companies will be well on their way to achieving digital transformation ...
Breaking Medicine News(10 mins):Health News:Beauty Entrepreneur creates hair extension smart machine and mobile app inspired by UBER technology 2Health News:OncLive® and Cleveland Clinic Team up to Provide News, Information About Cancer Research and Patient Care 2Health News:OncLive® and Cleveland Clinic Team up to Provide News, Information About Cancer Research and Patient Care 3Health News:The 26th Jerry Segal Classic Returns to Benefit Patients of Magee Rehabilitation Hospital 2Health News:The 26th Jerry Segal Classic Returns to Benefit Patients of Magee Rehabilitation Hospital 3Health News:Inmar Announces Program to Fuel Student Passion for STEM – with an Unconventional Twist 2Health News:e-Spirit boosts Corporate Content Cloud initiative with release of FirstSpirit 5.2 2Health News:e-Spirit boosts Corporate Content Cloud initiative with release of FirstSpirit 5.2 3
... Join Nationwide Campaign Challenging U.S. to Close the Gaps ... in Breast Cancer Care, Survival, ... of activists from seven California Affiliates of Susan G. Komen,for the ... the Komen Community Challenge, a nationwide tour to close,the gaps in ...
... , , MONDAY, Jan. 14 (HealthDay News) -- Tysabri, a controversial ... for patients with a moderate to severe form of another ... announced Monday. , But the drug also comes with a ... as well as other side effects, so it must be ...
... life. Thats the message from physicians at the University ... Abella, MD, MPhil, Clinical Research Director of Penns Center ... says bystanders can play a critical role in saving ... arrests that occur each year outside of hospitals in ...
... in the UK has improved significantly over the last 25 years ... Monitoring at 17 testing sites around the UK shows a fall ... and copper in the air we breathe. , Results show ... tested over the period. The total average concentration has fallen from ...
... Jan. 14 Fusion Energy,Products, manufacturer of Fusion(TM) 6+ ... Laboratories, Inc. (OTC Bulletin Board: BNLB), is proud,to announce ... its,sponsorship commitment to L&M Racing,s Supercross team for the ... Products., "BP and am/pm have been ongoing sponsors ...
... Assurant Health, a Milwaukee,WI-based national provider of individual ... today it entered into an agreement,that gives its ... and physicians., Under the agreement Assurant Health ... network, which will expand access to medical,facilities in ...
Cached Medicine News:Health News:California Affiliates of Susan G. Komen for the Cure Convene Celebrities, Breast Cancer Survivors and Activists to Challenge Elected Officials to Strengthen Breast Cancer Services 2Health News:California Affiliates of Susan G. Komen for the Cure Convene Celebrities, Breast Cancer Survivors and Activists to Challenge Elected Officials to Strengthen Breast Cancer Services 3Health News:MS Drug Tysabri Approved for Crohn's Disease 2Health News:MS Drug Tysabri Approved for Crohn's Disease 3Health News:Anyone can save a life: Penn researchers lead national efforts to improve CPR quality 2Health News:Anyone can save a life: Penn researchers lead national efforts to improve CPR quality 3Health News:Heavy metal slips down UK air quality charts 2Health News:Fusion Energy Teams Up With BP's 'am/pm' Stores to Enhance Supercross Sponsorship and Fusion Energy Products Distribution 2Health News:Assurant Health Gains Access to Great-West Healthcare's Nationwide Network 2Health News:Assurant Health Gains Access to Great-West Healthcare's Nationwide Network 3
(Date:9/1/2015)... Alpha Imaging LLC , a leading distributor of advanced medical imaging ... they have been awarded exclusive rights to represent the complete Shimadzu ... territory supplements Alpha Imaging,s existing Shimadzu sales and service responsibilities with ... Indiana , Pennsylvania , ... West Virginia , Delaware and ...
(Date:9/1/2015)... -- Results from an interim analysis of the Phase ... idarucizumab enabled emergency surgery to be initiated rapidly ... (Pradaxa ® dabigatran etexilate mesylate). The specific and ... enabled patients to be urgently brought to necessary ... between administration of idarucizumab and start of procedure. ...
(Date:9/1/2015)... Belgium , Sept. 1, 2015 VolitionRx ... on developing blood-based diagnostic tests for a broad range of ... Executive Officer, Cameron Reynolds , is scheduled to attend ... is being held September 9-10, 2015 in Boston, ... on September 10. Wells Fargo Securities Research ...
Breaking Medicine Technology:Alpha Imaging Expands Shimadzu Territory 2New Analysis Shows Idarucizumab* Enables Rapid Initiation of Emergency Surgery in Dabigatran-Treated Patients 2New Analysis Shows Idarucizumab* Enables Rapid Initiation of Emergency Surgery in Dabigatran-Treated Patients 3New Analysis Shows Idarucizumab* Enables Rapid Initiation of Emergency Surgery in Dabigatran-Treated Patients 4New Analysis Shows Idarucizumab* Enables Rapid Initiation of Emergency Surgery in Dabigatran-Treated Patients 5New Analysis Shows Idarucizumab* Enables Rapid Initiation of Emergency Surgery in Dabigatran-Treated Patients 6New Analysis Shows Idarucizumab* Enables Rapid Initiation of Emergency Surgery in Dabigatran-Treated Patients 7New Analysis Shows Idarucizumab* Enables Rapid Initiation of Emergency Surgery in Dabigatran-Treated Patients 8New Analysis Shows Idarucizumab* Enables Rapid Initiation of Emergency Surgery in Dabigatran-Treated Patients 9VolitionRx to Attend 10th Annual Wells Fargo Healthcare Conference on September 9-10, 2015 2VolitionRx to Attend 10th Annual Wells Fargo Healthcare Conference on September 9-10, 2015 3VolitionRx to Attend 10th Annual Wells Fargo Healthcare Conference on September 9-10, 2015 4
... Oct. 11 ECRI Institute® ( www.ecri.org ), an ... improving patient care, is pleased to announce Kaiser Permanente ... health plan,  as the winner of the 5th annual ... health technology management. The Health Devices Achievement Award ...
... N.C., Oct. 11 Talecris Biotherapeutics Holdings Corp. (Nasdaq: ... release before the market opens on October 28, 2010. Due ... be hosting a conference call to discuss its third quarter ... Inspiration. Dedication. Innovation. Talecris Biotherapeutics is ...
Cached Medicine Technology:ECRI Institute Names Kaiser Permanente Winner of 5th Annual Health Devices Achievement Award 2ECRI Institute Names Kaiser Permanente Winner of 5th Annual Health Devices Achievement Award 3
Complete Blink-N-Clean lens drops cleans and clears lenses in a blink. It is a unique blend of gentle to the eye ingredients that conveniently cleans, clears and keeps lenses feeling comfortable thro...
... preservative free lubricating and rewetting ... eyes while you're wearing soft ... free formula is ideal for ... to preservatives and for frequent ...
Saline Solution to rinse and store soft contact lenses and for heat disinfection....
Sensitive Eyes Plus Saline Solution to rinse soft contact lenses The unique, gentle, pH-balanced formula contains potassium, an ingredient found in tears....
Medicine Products: