Navigation Links
U of M researchers find childhood cancer risk rises with mother's age
Date:7/14/2009

Research from the Masonic Cancer Center, University of Minnesota indicates that a baby born to an older mother may have a slightly increased risk for many of the cancers that occur during childhood.

"Our finding shows that although the absolute risk is low, advancing maternal age may be a factor and explain why, after other factors are adjusted for, some children get cancer," said Logan Spector, Ph.D., assistant professor of pediatrics and cancer epidemiology researcher. Spector and Kimberly Johnson, Ph.D., post doctoral fellow in pediatric epidemiology, led the research team on this study. The results are published in the July 2009 issue of the journal Epidemiology.

Currently, about 1 in 435 children under the age of 15 in the United States gets cancer. Types of cancers most often affecting children include leukemia, lymphoma, central nervous system tumor, neuroblastoma, Wilms' tumor, bone cancer, and soft tissue sarcoma.

For this population-based case-control study, Spector and Johnson used information from birth registry records in New York, Washington, Minnesota, Texas, and California. The study included the records of 17,672 children in those states diagnosed with cancer at ages 0-14 years between 1980 and 2004 and 57,966 children not diagnosed with cancer.

"We saw that the risk of 7 of the 10 most common childhood cancers increased slightly, about 7-10 percent, with every five-year increase in maternal age," Spector said.

The researchers noted the father's age did not seem to matter once the mother's age was taken into account.

Spector and Johnson say more research needs to be done on why the risk for childhood cancer increases with advancing maternal age. Some of the possible explanations could be age-related changes in hormonal levels during pregnancy and alterations in DNA markings in eggs that can be transmitted to the offspring. "A mechanism of inherited mutation is consistent with our finding that the maternal age effect was strongest among children diagnosed with cancer at the earliest age," Spector said.

He anticipates that such research will take on greater importance as more women delay having children until older. Statistics show the percentage of babies born to women 30 years of age or older in the United States has risen from about 18 percent in 1970 to 37 percent in 2005.


'/>"/>

Contact: Sara Martin
buss@umn.edu
612-626-7037
University of Minnesota
Source:Eurekalert

Related medicine news :

1. Researchers map how staph infections alter immune system
2. Researchers identify individuals at risk for developing colon cancer
3. Arizona researchers to sequence West African rice strain
4. Six Researchers to Receive Prestigious Awards from the American Society of Hematology
5. Mount Sinai researchers find new Alzheimers disease treatment promising
6. Researchers consider herd movements to help eradicate bovine TB
7. Pre-cessation patch doubles quit success rate: Researchers call for labeling changes
8. Researchers identify potential patient safety risks among methadone maintenance treatment patients
9. Purdue researchers create prostate cancer homing device for drug delivery
10. Moles and melanoma -- researchers find genetic links to skin cancer
11. Australian researchers identify genes that cause melanoma
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2016)... , ... June 24, 2016 , ... People across the ... Genome magazine’s Code Talker Award, an essay contest in which patients and their families ... to be presented at the 2016 National Society of Genetic Counselors (NSGC) Annual Education ...
(Date:6/24/2016)... ... June 24, 2016 , ... Puradigm® & ... (TGIG), has initiated cultivation and processing operations at its production facility, and opened ... , Puradigm is the manufacturer of a complete system of proactive air and ...
(Date:6/24/2016)... ... June 24, 2016 , ... Venture Construction Group (VCG) sponsors ... on June 20th at the Woodmont Country Club at 1201 Rockville Pike, Rockville, Maryland, ... to helping service members that have been wounded in battle and their families. Venture ...
(Date:6/24/2016)... ... June 24, 2016 , ... Finally, a bruise cream that ... dermaka cream can be incorporated into the post-surgical treatment plans of a variety of ... , dermaka cream is very effective for bruising and causes a rapid resolution of ...
(Date:6/24/2016)... New York (PRWEB) , ... June 24, 2016 , ... ... marijuana patients optimize the ingestion of their medication by matching users with high quality ... users to compare pieces with no commitment. , Inhale was founded by two brothers, ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 ... CAPR ), a biotechnology company focused on the ... announced that patient enrollment in its ongoing randomized ... has exceeded 50% of its 24-patient target. Capricor ... the third quarter of 2016, and to report ...
(Date:6/23/2016)... BOGOTA, Colombia , June 23, 2016  Astellas today announced the establishment of Astellas Farma Colombia (AFC), a ... second affiliate in Latin America . ... ... ... ...
(Date:6/23/2016)... , June 23, 2016  Experian ... integrating and transforming the patient payment and ... several innovative new products and services that ... its revenue cycle offerings. These award-winning solutions ... efficient workflows, remain compliant in an ever-changing ...
Breaking Medicine Technology: