Navigation Links
Topical treatment for cold sores achieves efficacy of oral drugs; represents paradigm shift
Date:10/28/2008

WASHINGTON, D.C. (October 28, 2008) Scientists at NanoBio Corporation have demonstrated for the first time in humans that a novel topical treatment for cold sores (herpes labialis), NB-001, speeds healing of lesions as effectively as the leading oral systemic drugs but without safety or toxicity concerns.

The new data provide the first proof of principle that a topical agent can attain equivalent efficacy rates to oral systemic drugs, according to the NanoBio scientists. Topical treatments are widely considered inferior to oral systemic treatments because they fail to penetrate to the site of infection with adequate drug levels required to subdue infections.

In the study of 482 patients, NB-001 healed lesions 1.3 days faster than placebo as measured by investigators (P=0.006). Results of the randomized, double-blind, placebo-controlled, phase 2b trial are being presented at the 48th annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC)/Infectious Diseases Society of America (IDSA) 46th annual meeting in Washington, D.C.

NB-001 was well tolerated, without safety concerns or adverse events, and was not systemically absorbed. "NB-001 challenges the conventional wisdom that topical therapies are less effective, because NB-001 directly accesses the site of infection in the dermis and epidermis instead of remaining on top of the skin," said James R. Baker, Jr., M.D., founder and chairman of NanoBio Corp. "NB-001 employs a physical mode of action to disrupt the outer membranes of pathogens and prompt viral lysis, essentially killing on contact."

The study also suggests that the physical mode of action of NB-001 significantly reduces the likelihood that pathogens will develop resistance to the biocidal effect of the topical lotion.

"These characteristics make NB-001 an ideal candidate for first-line treatment with the potential for widespread use across a broad range of patients," said Mary Fla
'/>"/>

Contact: Becky Levine
blevine@medthink.com
919-786-4918
MedThink Communications
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Perrigo Company Announces FDA Approval for Ciclopirox Topical Solution
2. Perrigo Company Announces FDA Approval for Ciclopirox Topical Solution
3. Voltaren(R) Gel Receives US Regulatory Approval as the First Approved Topical Prescription Treatment for Pain Associated with Osteoarthritis
4. Warner Chilcott and NexMed Sign U.S. Collaboration for Topical Alprostadil Treatment for Erectile Dysfunction
5. Topical treatment for age spots, from Harvard Womens Health Watch
6. Summit VetPharm Introduces New Feline Topicals Vectra(TM) for Cats & Kittens and Vectra(TM) for Cats
7. International Federation of Sports Medicine Selects Celadrin(R) Topical Cream as its First and Only Official Joint and Muscle Topical Cream
8. ZARS Pharma Announces Worldwide License Agreement With Galderma Pharma S.A. for Pliaglis(TM), a Topical Local Anesthetic
9. Topical Cream Treats Precancerous Lesions of Vulva
10. ImQuest Presents New Anti-HIV Drug and Topical Microbicide Development Results on Lead Pyrimidinedione Products IQP-0410 and IQP-0528
11. Fougera First-to-Market With Calcipotriene Topical Solution 0.005% (Rx) (Scalp Solution)
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/1/2015)... ... September 01, 2015 , ... ... has announced that Edge Information Management has been granted continued accreditation based ... Council (BSCC). , “Achieving and maintaining this accreditation takes the involvement ...
(Date:9/1/2015)... MA (PRWEB) , ... September 01, 2015 , ... ... today announced the release of version 5.2 of the FirstSpirit Content Management System ... Cloud initiative. With the new version of FirstSpirit, companies will be well on ...
(Date:9/1/2015)... ... 2015 , ... Two of Washington D.C.’s most respected chefs are using their ... , Recently named “the next big thing” in the culinary world by Elle Spain, ... story behind food and reclaiming culinary traditions on the brink of extinction. According to ...
(Date:9/1/2015)... (PRWEB) , ... September 01, 2015 , ... ... the 2015-2016 Distinguished Nurse Scholar-in Residence at the Institute of Medicine (IOM) of ... of Biomedical Informatics at Columbia University School of Nursing. A member of the ...
(Date:9/1/2015)... (PRWEB) , ... September 01, 2015 , ... ... cards, launched its consumer-friendly, informational video this week to coincide with back-to-school and ... . , According to the CDC, elementary school children are sick an ...
Breaking Medicine News(10 mins):Health News:Edge Information Management Granted Continued NAPBS Accreditation 2Health News:Edge Information Management Granted Continued NAPBS Accreditation 3Health News:e-Spirit boosts Corporate Content Cloud initiative with release of FirstSpirit 5.2 2Health News:e-Spirit boosts Corporate Content Cloud initiative with release of FirstSpirit 5.2 3Health News:Chefs Amy Riolo and Luigi Diotaiuti Embark on Culinary Diplomatic Quest to Build Bridges through Global Cuisine 2Health News:Chefs Amy Riolo and Luigi Diotaiuti Embark on Culinary Diplomatic Quest to Build Bridges through Global Cuisine 3Health News:Chefs Amy Riolo and Luigi Diotaiuti Embark on Culinary Diplomatic Quest to Build Bridges through Global Cuisine 4Health News:Columbia Nursing’s Suzanne Bakken Named Distinguished Institute of Medicine Nurse Scholar-in-Residence 2Health News:USA Medical Card Launches New FAQ Video During Back-to-School 2
... AED industry-leading commitment to research and developmentGrand opening ... the American Academy of Dermatology (AAD)HAYWARD, Calif., March ... SLTM ) today announced the opening of the ... new product development, facilitate research on the innovative ...
... of Cosmetic Dermatology Finds Over-the-Counter (OTC) Albolene(R) Moisturizing Cleanser as ... Mild to Moderate EczemaEDISON, N.J., March 5 Mild to ... to control and heal this skin condition without a prescription ... in the March 2009 issue of the Journal of ...
... of metabolic syndrome in strained unions, study finds , , THURSDAY, ... an unhappy marriage may be greater for women than men, ... in "strained" unions, those marked by arguing and being angry, ... women in the contentious relationships were more likely to develop ...
... InfoLogix ensures a hospital,s communications system enables more efficient ... nightmare is having its communications system go down. But ... InfoLogix, Inc. (Nasdaq: IFLG ), ... out one of America,s largest and most reliable wireless ...
... Finance New Health Care Proposals At Today,s Summit?WHITE HOUSE TO ... released today by the Republican National Committee:(Logo: http://www.newscom.com/cgi-bin/prnh/20080519/RNCLOGO ) ... Summit : ... On Health Care Issues. "On Thursday, Mr. Obama ...
... EU and US Approvals for Intravenous Formulation of Temozolomide ... PresentationKENILWORTH, N.J., March 5 Schering-Plough Corporation (NYSE: ... and the US FDA both approved the intravenous (IV) ... approved oral form of the drug. Temozolomide is ...
Cached Medicine News:Health News:Solta Medical, Inc. Announces State-of-the-Art Aesthetic Center 2Health News:Solta Medical, Inc. Announces State-of-the-Art Aesthetic Center 3Health News:Commonly Used Beauty Staple Clinically Proven to Help Treat Eczema 2Health News:Commonly Used Beauty Staple Clinically Proven to Help Treat Eczema 3Health News:Bad Marriages Harder on Women's Health 2Health News:Bad Marriages Harder on Women's Health 3Health News:InfoLogix Implements Wireless Multi-Site Medical Communications Solution for Sisters of Mercy Health System 2Health News:InfoLogix Implements Wireless Multi-Site Medical Communications Solution for Sisters of Mercy Health System 3Health News:InfoLogix Implements Wireless Multi-Site Medical Communications Solution for Sisters of Mercy Health System 4Health News:InfoLogix Implements Wireless Multi-Site Medical Communications Solution for Sisters of Mercy Health System 5Health News:RNC: Tax and Spend Fever 2Health News:RNC: Tax and Spend Fever 3Health News:RNC: Tax and Spend Fever 4Health News:RNC: Tax and Spend Fever 5Health News:RNC: Tax and Spend Fever 6Health News:RNC: Tax and Spend Fever 7Health News:European Commission and United States Food and Drug Administration (FDA) Both Approve New Options for Patients With Certain Primary Brain Tumors 2Health News:European Commission and United States Food and Drug Administration (FDA) Both Approve New Options for Patients With Certain Primary Brain Tumors 3Health News:European Commission and United States Food and Drug Administration (FDA) Both Approve New Options for Patients With Certain Primary Brain Tumors 4Health News:European Commission and United States Food and Drug Administration (FDA) Both Approve New Options for Patients With Certain Primary Brain Tumors 5Health News:European Commission and United States Food and Drug Administration (FDA) Both Approve New Options for Patients With Certain Primary Brain Tumors 6Health News:European Commission and United States Food and Drug Administration (FDA) Both Approve New Options for Patients With Certain Primary Brain Tumors 7
(Date:9/1/2015)... , Sept. 1, 2015 Agena Bioscience TM ... Shanghai , a commercial and financial hub from which ... of genomic testing laboratories in mainland China ... of Agena Bioscience,s global sales with almost sixty MassARRAY ® ... China will allow us to expand our reach ...
(Date:9/1/2015)... September 2015 In nur zwei Jahren ... hat die SHL Group schnell weltweit 3.000 Mitarbeiter ... Wachstum auf dem Markt der injizierbaren ... das Management von SHL wieder. Foto ... weltweit führend in Design und Herstellung automatischer Injektoren ...
(Date:9/1/2015)... , Sept. 1, 2015 Egalet ... integrated specialty pharmaceutical company focused on discovering, developing, ... researchers will be  presenting scientific data on SPRIX ... abuse-deterrent, extended-release, oral morphine product candidate, and Egalet-002, ... at PainWeek 2015 to be held ...
Breaking Medicine Technology:Agena Bioscience Opens Office in Shanghai, China 2SHL Group erreicht wichtigen Markstein von 3.000 Mitarbeitern 2Egalet Announces Scientific Presentations at PainWeek 2015 Meeting 2Egalet Announces Scientific Presentations at PainWeek 2015 Meeting 3Egalet Announces Scientific Presentations at PainWeek 2015 Meeting 4Egalet Announces Scientific Presentations at PainWeek 2015 Meeting 5Egalet Announces Scientific Presentations at PainWeek 2015 Meeting 6
... Still River Systems, Inc. announces today that ... with the Massachusetts Institute of Technology (M.I.T.) to ... Plasma Science and Fusion Center in collaboration with ... in conjunction with its own leading-edge developments in ...
... Neuland Laboratories Ltd., a pharmaceutical manufacturer providing active pharmaceutical ... services to customers located in 85 countries, today announced ... manufacture at the 22nd American Peptide Symposium to be ... "It is fitting that we formally launch our ...
Cached Medicine Technology:Still River Systems Sign Patent License Agreement With the Massachusetts Institute of Technology 2Neuland Labs Launches Expanded Peptide Manufacturing Capabilities at 22nd American Peptide Symposium 2Neuland Labs Launches Expanded Peptide Manufacturing Capabilities at 22nd American Peptide Symposium 3
... quick and easy automated refill system ... space on your laboratory bench and ... easy-to-use, one-hand system, you only need ... of Diamond Tips. All sizes of ...
... TowerPack is an innovative, quick ... Diamond Tips. Use 60% less space ... less plastic. With this amazingly easy-to-use, ... box for the whole range of ...
10 L, Racked, 96 tips/rack Extended length pipette tips recommended for 5 and 10 L pipettes....
This pipette tip facilitates the loading of samples onto polyacrylamide gels for DNA sequencing. The Geloader Tip has a 15 mm capillary with a defined diameter of less than 0.3 mm. The flexibility of...
Medicine Products: