Navigation Links
Topical treatment for cold sores achieves efficacy of oral drugs; represents paradigm shift
Date:10/28/2008

WASHINGTON, D.C. (October 28, 2008) Scientists at NanoBio Corporation have demonstrated for the first time in humans that a novel topical treatment for cold sores (herpes labialis), NB-001, speeds healing of lesions as effectively as the leading oral systemic drugs but without safety or toxicity concerns.

The new data provide the first proof of principle that a topical agent can attain equivalent efficacy rates to oral systemic drugs, according to the NanoBio scientists. Topical treatments are widely considered inferior to oral systemic treatments because they fail to penetrate to the site of infection with adequate drug levels required to subdue infections.

In the study of 482 patients, NB-001 healed lesions 1.3 days faster than placebo as measured by investigators (P=0.006). Results of the randomized, double-blind, placebo-controlled, phase 2b trial are being presented at the 48th annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC)/Infectious Diseases Society of America (IDSA) 46th annual meeting in Washington, D.C.

NB-001 was well tolerated, without safety concerns or adverse events, and was not systemically absorbed. "NB-001 challenges the conventional wisdom that topical therapies are less effective, because NB-001 directly accesses the site of infection in the dermis and epidermis instead of remaining on top of the skin," said James R. Baker, Jr., M.D., founder and chairman of NanoBio Corp. "NB-001 employs a physical mode of action to disrupt the outer membranes of pathogens and prompt viral lysis, essentially killing on contact."

The study also suggests that the physical mode of action of NB-001 significantly reduces the likelihood that pathogens will develop resistance to the biocidal effect of the topical lotion.

"These characteristics make NB-001 an ideal candidate for first-line treatment with the potential for widespread use across a broad range of patients," said Mary Fla
'/>"/>

Contact: Becky Levine
blevine@medthink.com
919-786-4918
MedThink Communications
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Perrigo Company Announces FDA Approval for Ciclopirox Topical Solution
2. Perrigo Company Announces FDA Approval for Ciclopirox Topical Solution
3. Voltaren(R) Gel Receives US Regulatory Approval as the First Approved Topical Prescription Treatment for Pain Associated with Osteoarthritis
4. Warner Chilcott and NexMed Sign U.S. Collaboration for Topical Alprostadil Treatment for Erectile Dysfunction
5. Topical treatment for age spots, from Harvard Womens Health Watch
6. Summit VetPharm Introduces New Feline Topicals Vectra(TM) for Cats & Kittens and Vectra(TM) for Cats
7. International Federation of Sports Medicine Selects Celadrin(R) Topical Cream as its First and Only Official Joint and Muscle Topical Cream
8. ZARS Pharma Announces Worldwide License Agreement With Galderma Pharma S.A. for Pliaglis(TM), a Topical Local Anesthetic
9. Topical Cream Treats Precancerous Lesions of Vulva
10. ImQuest Presents New Anti-HIV Drug and Topical Microbicide Development Results on Lead Pyrimidinedione Products IQP-0410 and IQP-0528
11. Fougera First-to-Market With Calcipotriene Topical Solution 0.005% (Rx) (Scalp Solution)
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/15/2014)... San Diego, CA (PRWEB) September 15, 2014 ... website daily regarding all the latest information from the ... Following a previous announcement from the FDA, the Agency ... Labs (aka NuVision Pharmacy) the immediate recall ... on the market that are not expired due to ...
(Date:9/15/2014)... Lauderdale, FL (PRWEB) September 15, 2014 (PRWEB) September 15, ... and what’s not; what the startup business requirements are ... market the new business. , Speakers include industry professionals, ... Harborside Health Center in Oakland,CA and cannabis business ... CO , who are already successfully running legal marijuana ...
(Date:9/15/2014)... Recently, Top10BestSEOHosting.com has compared many professional ... http://www.greengeeks.com/cgi-bin/affiliates/clickthru.cgi?id=seohosts ), IX Web Hosting and GoDaddy are ... “These companies have outperformed other competitors in hosting ... we call them the Best VPS Hosting supplier. ... best web hosting to enjoy the power of ...
(Date:9/14/2014)... (PRWEB) September 15, 2014 Skin becomes dryer ... like sun damage and not moisturizing properly. However, there are ... has been cared for. , Two main reasons this occurs: ... of hyaluronic acid in the skin , During the aging ... of these are responsible for important moisture retention and radiance ...
(Date:9/14/2014)... St. Louis, MO (PRWEB) September 14, 2014 ... events can now use the Quotes Pros website to ... portal that was constructed this year at http://quotespros.com/life-insurance.html ... , The insurance company partners that are preparing ... this year are located in most U.S. states. As ...
Breaking Medicine News(10 mins):Health News:FDA Requests Recall of Sterile Drug Products by Downing Labs (aka NuVision Pharmacy): AttorneyOne Monitors and Keeps Consumers Informed 2Health News:How to Start And Run a Successful Legal Marijuana Business 2Health News:2 Reasons Skin Becomes Dryer with Age and What To Do About It, From Sublime Beauty® 2Health News:2 Reasons Skin Becomes Dryer with Age and What To Do About It, From Sublime Beauty® 3Health News:Quotes for Life Insurance Now Offered at New Consumer Portal Online 2
... MD, former chief of pediatrics at Women & Infants Hospital ... Brown University, was recently inducted into the Legends of Neonatology ... Oh was one of two physicians inducted this year for ... Later this month, Dr. Oh will also receive another prestigious ...
... Baltimore, MD A study released today by the ... Bloomberg School of Public Health has identified the most ... could offer the best hope yet for scaling up ... taking aim at the country,s precipitous number of child ...
... 12 (HealthDay News) -- A toxic component of a plant ... failure and upper urinary tract cancer, researchers warn. Aristolochic ... used for centuries and still are used in many countries. ... cancer in Taiwan concluded that aristolochic acid is a primary ...
... THURSDAY, April 12 (HealthDay News) -- Even though a child,s ... finds that the marriages and partnerships of parents of kids ... study debunks "a persistent myth that childhood cancer will have ... simply not true," said Anne Kazak, professor of pediatrics at ...
... , WEDNESDAY, April 11 (HealthDay News) -- The U.S. ... producers, drug companies and veterinarians to help limit the ... of mixing antibiotics in animal feed to make livestock, ... to disease has been criticized for years in many ...
... A first of its kind study conducted by ... (IPC) found that one fall requiring first responder emergency ... hours at Boston Logan International Airport, with 37 percent ... study, which was done at the request of the ...
Cached Medicine News:Health News:Dr. William Oh named 2012 Legend of Neonatology 2Health News:New study identifies promising, achievable solutions to Nigeria's childhood mortality crisis 2Health News:New study identifies promising, achievable solutions to Nigeria's childhood mortality crisis 3Health News:Herbal Remedy Ingredient Tied to Cancer, Kidney Failure 2Health News:Parents of Kids With Cancer No More Likely to Break Up 2Health News:FDA Seeks to Limit Antibiotics in Animal Feed 2Health News:FDA Seeks to Limit Antibiotics in Animal Feed 3Health News:BMC study shows diverting passengers to elevators could help reduce falls at Logan Airport 2
(Date:9/12/2014)... 12, 2014 The report ... (Alcoholic, CSD, Sports & Energy Drinks, Others), Food ... & Seafood)], by Material (Aluminum & Steel) - ... and segments the Food & Beverage Metal Cans ... in terms of volumes and values. The application ...
(Date:9/12/2014)... /PRNewswire-iReach/ -- 9 th Annual FDA Inspections Summit ... Bethesda, MD Early Bird Registration discount ends ... Photo - http://photos.prnewswire.com/prnh/20140912/145652 What ... to get a glimpse into the inner workings of ... Come to Washington ...
(Date:9/12/2014)... 2014 Research and Markets ... Medical Technologies Market 2014-2018" report to their ... collective term for software solutions, medical devices, imaging ... The Global Medical Technologies market covers active implantable ... vitro diagnostics technology, dental technology, electromechanical medical technology, ...
Breaking Medicine Technology:Food & Beverage Metal Cans Market Worth $49.20 Billion by 2019 2Food & Beverage Metal Cans Market Worth $49.20 Billion by 2019 3Food & Beverage Metal Cans Market Worth $49.20 Billion by 2019 4FDAnews Announces: Early Bird Registration Discount Ends Sept.19 for 9th Annual Inspections Summit, Oct. 22-24, 2014 2FDAnews Announces: Early Bird Registration Discount Ends Sept.19 for 9th Annual Inspections Summit, Oct. 22-24, 2014 3Global Medical Technologies Market 2014-2018: Key Vendors are GE, Johnson & Johnson, Medtronic, Roche and Siemens 2Global Medical Technologies Market 2014-2018: Key Vendors are GE, Johnson & Johnson, Medtronic, Roche and Siemens 3
Provides reliable information on the most commonly prescribed drugs, their side effects, interactions and cost of therapy....
Very concise book answering the question: "I've got a diagnosis, which drugs do I use?". All 15 chapters written by highly skilled US specialists...
Make better prescribing decisions with this drug interaction analyzer containing over 3,000 brand names with generic equivalents....
Davis's Drug Guide for Nurses - now with over 760 Integrated Calculators - combines the most comprehensive, up-to-date and practical drug resource with built in drug dosing calculation tools for most...
Medicine Products: