Navigation Links
Taking the needle's sting out of diabetes
Date:8/10/2009

Found in 30% of all human cancer tumors, the Ras protein literally "drives cells crazy," says Prof. Yoel Kloog, the dean of the Faculty of Life Sciences at Tel Aviv University. Prof. Kloog was the first in the world to develop an effective anti-Ras drug against pancreatic cancer, currently in clinical trials. Now, new research published in the June issue of the European Journal of Pharmacology shows that the drug might be able to slow the progression of diabetes as well.

Prof. Kloog's student Adi Mor of TAU's Department of Neuro-biochemistry and Sackler School of Medicine has modified Prof. Kloog's anti-Ras FTS compound to develop what could be the first tablet-based treatment for children and adults with Type 1 diabetes. Early results show that FTS is effective in restoring insulin production in animal models ― which could spell an end to the daily needle injections endured by diabetics.

"Our anti-Ras compound has shown very positive results in inhibiting diabetes," says Mor. And given the drug's history FTS has already passed toxicity studies for other diseases and disorders it has the potential to fast-track through FDA regulatory hurdles, skipping straight to Phase II clinical trials. A new drug for diabetes could be ready in as little as five years' time.

Helping the immune system do its job

Previous studies by Prof. Kloog's lab found that the FTS compound is effective against autoimmune diseases such as multiple sclerosis and lupus, "but the mechanism of its effects on immune cells was not well understood," says Mor. "I wanted to see if there was a connection between Ras and the regulation of the immune system, and if so if FTS could help regulate it to prevent or slow diabetes."

Through treating cells with the Tel Aviv University FTS compound, Mor was able to find and isolate an important immune system regulator protein called Foxp3. This protein keeps T cells in the immune system in check.
'/>"/>

Contact: George Hunka
ghunka@aftau.org
212-742-9070
American Friends of Tel Aviv University
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. Mathematics taking guesswork out of plastic surgery tissue transfer
2. Looking to Shape Up for Summer? The Solution May Be the Steps Youre Already Taking
3. Swine Flu Vaccine Taking Longer Than Expected
4. Drug Limits Stomach Trouble in Patients Taking Low-Dose Aspirin
5. Looking to Shape up for Summer? The Solution May be the Steps Youre Already Taking
6. Taking Aim at Relapse of Leukemia in Kids
7. Value of Taking Aspirin to Cut Heart Risk Varies
8. Financial Distress Taking Toll on Employee Health
9. Taking a Bite Out of Rabies: Merial Provides Rabies Awareness and Prevention Training to Noahs Wish Pet Disaster Relief Organization
10. Chronic diarrhea unresponsive to conventional medication: Are you taking lansoprazole?
11. Taking folic acid for a year before pregnancy may reduce risk of preterm birth
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Taking the needle's sting out of diabetes
(Date:5/22/2015)... (PRWEB) May 22, 2015 Steven Winter ... Marc Zuluaga, has been selected by Consulting-Specifying Engineer (CSE) ... award winners are featured in the May/June issue of ... building industry professionals age 40 and younger who have, ... community, as well as in other areas of their ...
(Date:5/22/2015)... 22, 2015 A new program for ... in the field of Physical Therapy. , James ... the mystery out of physical therapy and discusses how ... motion for a variety of ailments and injuries. ... personalized exercise plan that enhances daily activities such as ...
(Date:5/22/2015)... Chicago, IL (PRWEB) May 22, 2015 ... Chunk Fitness patrons, the section containing particular muscles stretches ... weeks. With nearly 50% of stretches now complete, Chunk ... videos are planned to be filmed and released at ... stretches can be found here: http://www.chunkfitness.com/stretches . , ...
(Date:5/22/2015)... Viejo, CA (PRWEB) May 22, 2015 ... editable lower thirds designed exclusively for Final Cut Pro ... compatible with any design. , Intuitive on-screen-controls allow ... unique lower third. Reflections, colors, layouts, and much more ... Inspector window. , Pro3rd Impression comes ...
(Date:5/21/2015)... Los Angeles, California (PRWEB) May 21, 2015 ... Angeles area at the Hilton Hotel in San Gabriel on ... heard over and over again from men and women who ... can find the right partner." , "Many singles think that ... right person. The seeker would go from one relationship to ...
Breaking Medicine News(10 mins):Health News:Steven Winter Associates’ Marc Zuluaga Earns Innovative Engineering Award 2Health News:Developers at Pixel Film Studios Release Pro3rd Impression for Final Cut Pro X. 2Health News:Bestselling Author Sheds Light on Why Modern Dating is Hurting People's Chances of Finding a Lasting Relationship 2
... , ... ... ... ...
... ... ... ... ...
... PARK, Md. The U.S. ,race gap, in the commission of ... with murder arrest rates for African Americans out-distancing those for whites ... Florida State University and the University of Oregon. While ... 1970s, it grew again in the ,80s with the advent of ...
... abstain tend to gain the most, study finds, though reasons ... staying slim as one of the apparent benefits of light-to-moderate ... that women who drank the equivalent of one to two ... 30 percent less likely, in fact, than teetotalers. , "Our ...
... ... Fitness has emerged as Idaho,s much needed solution to inefficient workouts, expensive membership contracts, ... have fun, be challenged, and achieve goals. And, yes, it,s all guaranteed. , ... (PRWEB) March 8, 2010 ...
... ... highest honors in the industry. , ... March 8, 2010 -- The Sturge-Weber Foundation honored renowned dermatologist Dr. David J. Goldberg with one ... Dr. Goldberg is a pioneer in the field of dermatology and director of ...
Cached Medicine News:Health News:MMG Welcomes Ann Kottcamp to Leadership Team 2Health News:MMG Welcomes Ann Kottcamp to Leadership Team 3Health News:Payless ShoeSource Democratizes Health and Wellness With Launch of Champion Fitness Toning Footwear for Women 2Health News:Payless ShoeSource Democratizes Health and Wellness With Launch of Champion Fitness Toning Footwear for Women 3Health News:Payless ShoeSource Democratizes Health and Wellness With Launch of Champion Fitness Toning Footwear for Women 4Health News:Payless ShoeSource Democratizes Health and Wellness With Launch of Champion Fitness Toning Footwear for Women 5Health News:Payless ShoeSource Democratizes Health and Wellness With Launch of Champion Fitness Toning Footwear for Women 6Health News:Payless ShoeSource Democratizes Health and Wellness With Launch of Champion Fitness Toning Footwear for Women 7Health News:Payless ShoeSource Democratizes Health and Wellness With Launch of Champion Fitness Toning Footwear for Women 8Health News:Violent crime 'race gap' narrows, but persists in US 2Health News:Violent crime 'race gap' narrows, but persists in US 3Health News:Light Drinking Might Help Keep Women Slim 2Health News:Unique Equipment, Fun Workouts, Extraordinary Results 2Health News:The Sturge-Weber Foundation Honors Dr. David J. Goldberg 2Health News:The Sturge-Weber Foundation Honors Dr. David J. Goldberg 3
(Date:5/22/2015)... May 22, 2015 The leading companies ... billion global cardiac rhythm management device market dominate ... that Medtronic, St. Jude Medical, Boston Scientific and ... this market segment. The healthcare market research publisher,s ... uses 2015 as a base year, providing forecasts ...
(Date:5/22/2015)... ROCKVILLE, Md. , May 22, 2015 /PRNewswire/ ... "RegeneRx") today announced a peer-reviewed publication of the ... study evaluating RGN-259 (RegeneRx,s preservative-free eye drops) for ... Inc.,s controlled adverse environment (CAE ® ) model.  ... and the results, which were previously disseminated by ...
(Date:5/22/2015)... 2015 Research and Markets ( ... "Latest Regulations on Pharmaceutical International Multi-Center Clinical ... This is first time in history, ... international multi-center clinical trials of drugs in ... be implemented on March 1, 2015. The guidance ...
Breaking Medicine Technology:Kalorama: Top Companies Dominate Cardiac Defibrillator Market 2Kalorama: Top Companies Dominate Cardiac Defibrillator Market 3Kalorama: Top Companies Dominate Cardiac Defibrillator Market 4Complete Data from RegeneRx Phase II Dry Eye Trial Published in Current Issue of Clinical Ophthalmology 2Complete Data from RegeneRx Phase II Dry Eye Trial Published in Current Issue of Clinical Ophthalmology 3Complete Data from RegeneRx Phase II Dry Eye Trial Published in Current Issue of Clinical Ophthalmology 42015 Regulations on Pharmaceutical International Multi-Center Clinical Trials in China 2
... Tyrima Demonstrates Good Safety Profile and Excellent,Pharmacokinetic Properties ... /PRNewswire/ --,CeNeRx BioPharma, Inc., a clinical stage company ... central,nervous system, today announced top-line results from a ... for the treatment,of depression and anxiety. In this ...
... /PRNewswire-FirstCall/ - Oncolytics,Biotech Inc. announced today ... reovirus in combination with gemcitabine is ... Cancer Research (AACR),website at <a target="_blank" ... at <a target="_blank" href=,"http://www.oncolyticsbiotech.com/">www.oncolyticsbiotech.com .,The abstract ...
Cached Medicine Technology:CeNeRx BioPharma Announces Positive Phase I Results in First Human,Trial of Third Generation RIMA Antidepressant 2CeNeRx BioPharma Announces Positive Phase I Results in First Human,Trial of Third Generation RIMA Antidepressant 3Oncolytics Biotech Inc. Collaborators to Present,Reovirus/Gemcitabine Combination Research at AACR Annual Meeting 2Oncolytics Biotech Inc. Collaborators to Present,Reovirus/Gemcitabine Combination Research at AACR Annual Meeting 3
Anti-RSV IgA Assay (ELISA)....
Anti-RSV IgG Assay (ELISA)....
Rapid Immunoassay for the detection of Respiratory Syncytial Virus....
BD Directigen RSV Test fast, easy and accurate, its truly STAT. And it will help your laboratory quickly and confidently support critical antiviral therapy recommendations....
Medicine Products: