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Synthetic Marijuana Use Linked to Kidney Damage
Date:2/12/2013

TUESDAY, Feb. 12 (HealthDay News) -- Synthetic marijuana products, also known as Spice or K2, are potentially very dangerous for the kidneys, new research suggests.

Case studies analyzed by doctors from the University of Alabama at Birmingham found that this designer drug, which mimics the effects of marijuana, has been directly linked to serious kidney damage.

The researchers suggested that doctors should suspect the use of synthetic marijuana when patients, particularly young adults, have unexplained acute kidney damage. They pointed out these man-made drugs can't be detected in routine drug screenings.

"Cases of acute coronary syndrome associated with synthetic marijuana use have been reported, but our publication is the first to associate use with acute kidney injury," study co-author Dr. Gaurav Jain, an assistant professor in the nephrology division, said in a university news release. Abnormally rapid heart rate and seizures have also been reported with synthetic marijuana use, he noted.

The doctors examined four cases of acute kidney damage that were linked to the use of synthetic marijuana. In each case, an otherwise healthy young man went to the emergency room due to nausea, vomiting and abdominal pain after using the drug. All of the men, the researchers noted, lived in the same town in northeastern Alabama, and all of the cases occurred within a nine-week period.

Three of the men had an acute kidney injury that caused their volume of urine to be abnormally low. The fourth man had a drop in effective blood flow to the kidney. Three of the men had a kidney biopsy that showed the death of cells in the kidney that secrete, reabsorb, collect and transport urine. Although this condition can lead to kidney failure, in these cases the men regained their kidney function and did not need dialysis, the study authors noted in the news release.

Because all of the men had used synthetic marijuana, the doc
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