Navigation Links
Study shows no increased risk of breast cancer for non-carriers in families with BRCA gene mutation
Date:10/31/2011

lia (799) and Canada (1,034) through a consortium called the Breast Cancer Family Registry. They found 292 families in which a woman had a BRCA mutation. This is the largest analysis to date of breast cancer risk of non-carriers of family-specific BRCA mutations.

They compared the risk of breast cancer among first-degree relatives of breast cancer patients who did and did not carry a BRCA mutation and found no significant difference. This means that non-carriers of a familial BRCA mutation did not have a markedly elevated risk of developing breast cancer.

The investigators also found that a small percentage of women - 3.4 percent of women in the general populations of Australia, Canada and the U.S. - who are at highest risk for unexplained reasons (reasons other than a BRCA mutation) account for approximately 32 percent of all breast cancer cases, reflecting the wide range of factors that could play a role in breast cancer development. Recent research suggests that many different genetic variants affect breast cancer risk, and that the women at highest risk have inherited many of these variants.

"Earlier reports of higher risk among non-carriers of family-specific BRCA mutations compared to risks in the general population may reflect a comparison of women with and without a family history of breast cancer," noted senior author Alice Whittemore, PhD, professor of epidemiology and biostatistics at Stanford University School of Medicine. "The control group we used - relatives of breast cancer patients in families without a BRCA mutation - was important. The results suggest that women who test negative for their family's BRCA mutation have no greater breast cancer risk than a woman who also has relatives with breast cancer but no family-specific mutation."


'/>"/>
Contact: Nicole Fernandes
nicole.fernandes@asco.org
571-483-1354
American Society of Clinical Oncology
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. The freshman 15 is just a myth, nationwide study reveals
2. First-of-its-kind study creates new tool for targeted cancer drug development
3. Study finds community counseling reduced the prevalence of TB on a budget
4. Practice Doesnt Always Make Perfect, Study Suggests
5. NYUCN receives $4.2 million NIH/NIDA grant to study injecting drug users in Kenya
6. NYUCN receives $2.8 million NIH/NIAID grant to study combination HIV prevention for Kenyan youth
7. Study finds no link between elderly patient activity and hospital falls
8. UT study looks at manual wheelchair use, exercise and calorie burning
9. Study finds specific gene linked to cold sore susceptibility
10. Poorer Countries Have Higher Rates of Stroke, Study Finds
11. NYUCN receives $299 thousand from NCSBN to study patient safety in nursing homes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/17/2014)... -- Expectant parents should leave prenatal picture-taking to medical ... Use of ultrasound imaging and heartbeat monitors to get ... agency warns. "Although there is a lack ... and heartbeat monitors, prudent use of these devices by ... FDA biomedical engineer, said in an agency news release. ...
(Date:12/17/2014)... HealthDay Reporter , TUESDAY, Dec. 16, ... America, and work commitment is a big reason why, new ... said Dr. Mathias Basner, an assistant professor of sleep and ... of Medicine. A time-use survey of nearly 125,000 Americans, ... main activity exchanged for sleep. Short sleepers -- those who ...
(Date:12/15/2014)... 15, 2014 South Florida’s leading urgent care ... can be a daze of hassle, hustle, and bustle that ... decking halls, to burns when making special meals and heartburn ... can happen at any time. To prevent this season of ... made a list of helpful and healthful holiday tips to ...
(Date:12/15/2014)... News) -- Expert pilots process visual information more efficiently ... better decisions during landings, a new study shows. ... pilots to master, and 36 percent of all airplane ... final approach and landing. Researchers monitored the brain ... pilots while they were at the controls of a ...
(Date:12/15/2014)... 15, 2014 At the leading, long-established ... AutismOne and Focus Autism will welcome ... research on the effects of toxins to children’s health, ... information. , Luminaries such as Dr. Lucija Tomljenovic ... with esteemed, credentialed colleagues of the United States to ...
Breaking Medicine News(10 mins):Health News:FDA Warns Against Fetal 'Keepsake' Videos 2Health News:Work Steals Valuable Sleep Time, Study Finds 2Health News:Work Steals Valuable Sleep Time, Study Finds 3Health News:MD Now Urgent Care Presents Healthy Holiday Tips 2Health News:MD Now Urgent Care Presents Healthy Holiday Tips 3Health News:Study Shows Why Expert Pilots Are Experts 2Health News:AutismOne and Focus Autism Collaborate on Scientific Conference; International Group of Researchers to Present in Chicago, May 2015 2Health News:AutismOne and Focus Autism Collaborate on Scientific Conference; International Group of Researchers to Present in Chicago, May 2015 3
... Ecosystem Assessment, scientists have said that degradation of the eco ... human health and may cause greater harm in next 50 ... to cause a major outbreak and new diseases are emerging ... system are being used in unsustainable way. ,The report ...
... and 799 non-diabetic women volunteers in the age group ... Center, Seattle, US had said that being diabetic increases ... women who have had their menopause. ,The researchers ... hemoglobin A1c, urine culture, residual bladder volume and diabetes ...
... into a data comprising of 5461 girls between 11 to ... makes these girls more prone to stress fractures. ,The ... vigorous physical activity, which often lasts for 16 or more ... risk of having a stress fracture than the girls doing ...
... that tumor necrosis factor (TNF)-á-blocking therapy used for ... ,The study done by the Dutch scientists ... Netherlands had taken into account the number and ... with the TNF-á-blocking therapy. 128 dermatological conditions in ...
... of University of Mississippi Medical Center US have found ... hypertension and high blood pressure. ,3216 people who ... subjected to 24 hr monitoring of systolic and diastolic ... to mean daytime and nighttime systolic and diastolic blood ...
... rats suggests that eating onions may be the key to ... have identified a compound in onions, a peptide called GPCS ... involved segregation of bone cells of newborn mice that were ... These cells were later exposed to the peptide GPCS. The ...
Cached Medicine News:
(Date:12/15/2014)... Dec. 12, 2014 Research and Markets ... of the "MEMS Gyroscopes Analog Devices ADIS16136 ... report to their offering. ... tactical grade applications made a lot of progress ... reliability. They are now accepted in high-reliability environments, ...
(Date:12/15/2014)... and Markets ( http://www.researchandmarkets.com/research/32cmct/inferior_vena ) has announced ... Filters - Global Trends, Estimates and Forecasts, 2012-2018" ... http://photos.prnewswire.com/prnh/20130307/600769 Global Inferior Vena Cava (IVC) ... 2016. The North America accounts ... Europe claims approximately 27% (2018). ...
(Date:12/15/2014)... BerGenBio AS, a biopharmaceutical company ... cancers, today announces that it has raised NOK90 million ... and existing investors. BerGenBio will use the ... its pipeline of innovative cancer therapeutics, in particular an ... BGB324, a first-in-class selective Axl kinase inhibitor, which is ...
Breaking Medicine Technology:MEMS Gyroscopes Analog Devices ADIS16136 Precision Angular Rate Sensor Reverse Costing Analysis 2Inferior Vena Cava (IVC) Filters - Global Trends, Estimates and Forecasts, 2012-2018 2Inferior Vena Cava (IVC) Filters - Global Trends, Estimates and Forecasts, 2012-2018 3Inferior Vena Cava (IVC) Filters - Global Trends, Estimates and Forecasts, 2012-2018 4BerGenBio Completes NOK90 Million Fundraising 2
... Aug. 17 Luminex Corporation (Nasdaq: LMNX ... it has donated the first commercial unit of its ... his scientific team at the Papua New Guinea Institute ... in Papua New Guinea to progress malaria research led ...
... Equinox Surgical Solutions LLC today announced ... designed and developed by a minimally invasive, Board Certified, ... and his team to improve patient and surgical team ... acquire, hand-off, dispose of and reload sutures with an ...
Cached Medicine Technology:Luminex Donates Company's First MAGPIX Multiplexing System to Papua New Guinea Institute of Medical Research 2Luminex Donates Company's First MAGPIX Multiplexing System to Papua New Guinea Institute of Medical Research 3Equinox Surgical Solutions Launches Flagship Product, SutureAssist® 2
... Neonatal and Pediatric TRACH ... a multi access catheter ... lavage/irrigation port and locking ... sizes and packaging configurations. ...
... Stainless steel spiral reinforced. X-ray opaque. Super ... band. Single use. Adjustable Flange: The flange ... to suit the thickness of the cervical ... clockwise until the flange is tightly connected ...
... ULTRA® Suctionaid® tracheostomy tubes provide an additional ... from above the tracheostomy tube cuff. , ... tubes provide an additional lumen to permit ... tracheostomy tube cuff helping to reduce the ...
The soft silicone design promotes patient comfort. , ,Bivona® laryngectomy tubes feature a soft compliant silicone design for patient comfort....
Medicine Products: