Study shows no increased risk of breast cancer for non-carriers in families with BRCA gen... ( said study first author Allison Kurian...)

Study shows no increased risk of breast cancer for non-carriers in families with BRCA gene mutation

Date:10/31/2011

," said study first author Allison Kurian, MD, assistant professor of medicine and health research and policy at Stanford University School of Medicine. "One strength of the current study is the control women it used as a yardstick for comparing the breast cancer incidence in non-carriers of family-specific mutations. The control women were also relatives of breast cancer patients, but of patients without mutations. This is a more appropriate yardstick than average risk in the general population, since close relatives of all breast cancer patients have somewhat higher than average risks."

Women who inherit a mutation in the BRCA1 or BRCA2 gene carry a 5- to 20-fold higher risk of developing breast or ovarian cancers. First-degree relatives who have not inherited the same familial BRCA mutation have been considered to have a considerably lower risk for breast cancer.

In 2007, a study of women who tested negative for a specific familial BRCA mutation showed they had a 2- to 5-fold increased risk of developing breast cancer; which could be considered comparable to the risk of having a BRCA mutation. According to Kurian, the results raised concerns that non-carriers might require similar screening and preventive measures as their mutation-carrying relatives, such as annual breast MRI and prophylactic surgery, and cast some doubt on the meaning of a negative BRCA test.

Kurian said that the studies had looked at women who were in cancer family clinics and compared their breast cancer risk to that of women in the general population. Women from cancer family clinics were more likely to have intensive screening, and breast cancer risks tend to be higher among close relatives of breast cancer patients than those in the general population.

The investigators took a different approach in this research by studying women with breast cancer in 3,047 families in three population-based cancer registries in Northern California (1,214), Austra
'/>"/>

Contact: Nicole Fernandes
nicole.fernandes@asco.org
571-483-1354
American Society of Clinical Oncology
Source:Eurekalert

0

GOOD

Page: 1 2 3
Related medicine news :

1. The freshman 15 is just a myth, nationwide study reveals
2. First-of-its-kind study creates new tool for targeted cancer drug development
3. Study finds community counseling reduced the prevalence of TB on a budget
4. Practice Doesnt Always Make Perfect, Study Suggests
5. NYUCN receives $4.2 million NIH/NIDA grant to study injecting drug users in Kenya
6. NYUCN receives $2.8 million NIH/NIAID grant to study combination HIV prevention for Kenyan youth
7. Study finds no link between elderly patient activity and hospital falls
8. UT study looks at manual wheelchair use, exercise and calorie burning
9. Study finds specific gene linked to cold sore susceptibility
10. Poorer Countries Have Higher Rates of Stroke, Study Finds
11. NYUCN receives $299 thousand from NCSBN to study patient safety in nursing homes

Post Your Comments:

(Date:5/25/2013)... Sun City Center, FL (PRWEB) May 25, 2013 ... years, is one of many of the NALA’s businesses throughout ... Owner, Craig Amshel chose to participate in the nationwide event ... served as a Lieutenant Colonel in the Army. He said, ... work in the community I serve, but I live here ...

(Date:5/25/2013)... New York,NY (PRWEB) May 25, 2013 ... SizeItUp officially declared the integration of the 2012 ... Lamborghini Aventador is the latest entrant in the list ... Designed intelligently, the vehicle is all set to thrill ... with vicious acceleration power and spectacular looks, the 2012 ...

(Date:5/25/2013)... (PRWEB) May 25, 2013 Dr. Farooq ... surgery clinic in Dubai, has announced his practice’s adoption ... is the only FDA-cleared femtosecond laser proven with more ... safety and precision of LASIK. , “We are happy ... Advanced Femtosecond Laser at our Dubai LASIK practice,” Ashraf ...

(Date:5/25/2013)... IBISWorld estimates that revenue for the Cell ... of 28.7% to $1.0 billion in the five years to ... 2008, no new cell therapy products were introduced, according to ... that period. In the years since, however, the Food and ... contributed to the industry's fast growth during the five years ...

(Date:5/25/2013)... (PRWEB) May 25, 2013 Ayurveda ... Ayurveda means "knowledge or wisdom of life". While a medical ... and the transformation of consciousness. Its fundamental philosophy is that ... with our environment. It believes that in order to re-establish ... of harmony and then adopt a life style which brings ...

Breaking Medicine News(10 mins):Health News:Dr. Craig Amshel of Absolute Surgical Specialists Offering Bowel Prep During the Shop Local for a Cause Event 2 Health News:Rim Fitments Provider SizeItUp Launches The Database Integration For The 2012 Lamborghini Aventador 2 Health News:Atlanta Vision Clinic Acquires the Latest in Blade-Free Lasik Technology Bringing Dubai Patients the Intralase Method 2 Health News:Slow Healing: Cell Therapy in the US Industry Market Research Report Now Available from IBISWorld 2 Health News:Slow Healing: Cell Therapy in the US Industry Market Research Report Now Available from IBISWorld 3 Health News:Ayurveda Education Programs Offered by the California College of Ayurveda Include Panchakarma Certification, Practitioner Courses, and Body Therapy Classes 2

[0] Dr. Craig Amshel of Absolute Surgical Specialists Offering Bowel Prep During the Shop Local for a Cause Event [0] Rim Fitments Provider SizeItUp Launches The Database Integration For The 2012 Lamborghini Aventador [0] Atlanta Vision Clinic Acquires the Latest in Blade-Free Lasik Technology Bringing Dubai Patients the Intralase Method [0] Slow Healing: Cell Therapy in the US Industry Market Research Report Now Available from IBISWorld [0] Ayurveda Education Programs Offered by the California College of Ayurveda Include Panchakarma Certification, Practitioner Courses, and Body Therapy Classes

... ... and best-selling author Mary Shomon is launching a new campaign to help promote public awareness ... well as a free downloadable ebook, a Youtube video, and a Facebook social networking page. ... (PRWEB) January 12, ...

... HARRISBURG, Pa. , Jan. 12 Capital BlueCross is ... of have been resolved for former Turbine Airfoil Designs (TAD) employees ... its premiums and subsequently went out of business. , Last ... paying its health insurance premiums since October, and that their coverage ...

... , , WEST PALM ... Healthcare & Medical Tourism Conference Korea ( http://www.asiamedicaltourismcongress.com ) will ... a joint initiative between the Medical Tourism Association (MTA) and ... of the emerging leading destinations for medical tourism and global ...

... Number of Donors Continues Organization,s Role of Leading OPO in U.S. ... Jr. waited over four years for one phone call – a ... Boris was placed on the heart transplant waiting list in late 2004 ... arrived on April 25, 2009 , thanks to the generosity of ...

... symptoms occur, researchers say , TUESDAY, Jan. 12 ... is more accurate than some other commonly used ... symptoms, according to U.S. researchers. , So-called "paraneoplastic ... breast, ovarian and other types of cancer when ...

... 50 adds to likelihood of diagnosis, study finds , TUESDAY, ... who had pancreatic cancer before age 50 face a greatly ... , Researchers already knew that people with several relatives diagnosed ... develop the disease, but it wasn,t clear whether the relatives, ...

It's January...Do You Know Where Your Thyroid Is? Thyroid Awareness Month Focuses on Millions of Undiagnosed Americans with Thyroid Problems Capital BlueCross and Local Providers Reach Solution for Health Care Claims of Former Turbine Airfoil Designs Employees Global Healthcare & Medical Tourism Conference Korea Announced for April 13-16th, 2010 Gift of Life Breaks National Record for Life-Saving Organ Donations Combo PET-CT Scans Can Spot Hidden Cancers With Pancreatic Cancer, Age Factors Into Familial Risk

(Date:5/24/2013)... -- The potential of the pulmonary route ... agents has been receiving undeniable attention with the recent ... The crucial formulation considerations for orally inhaled products together ... role in the efficiency of pulmonary delivery, and great ... formulation techniques and devices in recent years. ...

(Date:5/23/2013)... PARÍS, 24 de mayo de 2013 Volcano ... desarrollador y fabricante de herramientas de precisión para ... tratamiento de la enfermedad vascular periférica y coronaria, ... ( Ad enosine V asodilator I ... durante la sesión de ensayo clínico hot line ...

(Date:5/23/2013)... Nephros, Inc. (OTC Bulletin Board: ... develops and sells high performance liquid purification ultrafilters, announced ... addition, the concurrent temporary reduction in exercise price for ... 2013. Nephros estimates that it will receive ... A portion of the proceeds will be used for ...

Breaking Medicine Technology:Inhalaltion Drug Delivery: 11-12 September - Berlin, Germany 2 Volcano anuncia los resultados preliminares del estudio ADVISE II y su inclusión en el ensayo SYNTAX2 2 Volcano anuncia los resultados preliminares del estudio ADVISE II y su inclusión en el ensayo SYNTAX2 3 Volcano anuncia los resultados preliminares del estudio ADVISE II y su inclusión en el ensayo SYNTAX2 4 Volcano anuncia los resultados preliminares del estudio ADVISE II y su inclusión en el ensayo SYNTAX2 5 Volcano anuncia los resultados preliminares del estudio ADVISE II y su inclusión en el ensayo SYNTAX2 6 Nephros Announces Completion of Rights Offering 2 Nephros Announces Completion of Rights Offering 3 Nephros Announces Completion of Rights Offering 4

[0] Inhalaltion Drug Delivery: 11-12 September - Berlin, Germany [0] Volcano anuncia los resultados preliminares del estudio ADVISE II y su inclusión en el ensayo SYNTAX2 [0] Nephros Announces Completion of Rights Offering

... 18, 2012 UCB, Inc., a leading biopharmaceutical company ... severe central nervous system and immunological disorders, is marking ... reinforcing its commitment to improving the lives of patients ... this year,s DDW meeting. "DDW is ...

... The new arthroscopy simulator ArthroS trains orthopedic surgeons for ... The Swiss company VirtaMed AG is launching ArthroS™, a ... get the chance to practice different operations numerous times ... as pilots improve their skills on flight simulators. ArthroS™ ...

Cached Medicine Technology:UCB Proudly Reinforces Long-Standing Commitment to Crohn's Disease Community at Digestive Disease Week 2012 2 UCB Proudly Reinforces Long-Standing Commitment to Crohn's Disease Community at Digestive Disease Week 2012 3 UCB Proudly Reinforces Long-Standing Commitment to Crohn's Disease Community at Digestive Disease Week 2012 4 Swiss Engineering for Surgical Perfection 2 Swiss Engineering for Surgical Perfection 3

UCB Proudly Reinforces Long-Standing Commitment to Crohn's Disease Community at Digestive Disease Week 2012 Swiss Engineering for Surgical Perfection

... a new standard in QPCR with the ... system offers superior performance, more flexibility, and ... system - with Windows 98SE and Pentium ... Premier Sound Speakers, Surge Protector (US only), ...

... The LightCycler System is the ... The LightCycler System enables you to ... 30 min, and simultaneously quantify and ... during amplification. The unique Melting Curve ...

... ABI PRISM 7900HT Sequence Detection System ... that detects and quantitates nucleic acid ... 384-well plate capability make the 7900HT ... high-throughput requirements of todays drug discovery ...

Sealing Mat for 96-well, 2.0ml, Deep Well, Square Available Sterile...

Medicine Products:

Mx4000 Multiplex Quantitative PCR System LightCycler Instrument ABI PRISM 7900HT Sequence Detection System 96-well, Deep Well Plate Sealing Mat