Navigation Links
Study shows no increased risk of breast cancer for non-carriers in families with BRCA gene mutation
Date:10/31/2011

," said study first author Allison Kurian, MD, assistant professor of medicine and health research and policy at Stanford University School of Medicine. "One strength of the current study is the control women it used as a yardstick for comparing the breast cancer incidence in non-carriers of family-specific mutations. The control women were also relatives of breast cancer patients, but of patients without mutations. This is a more appropriate yardstick than average risk in the general population, since close relatives of all breast cancer patients have somewhat higher than average risks."

Women who inherit a mutation in the BRCA1 or BRCA2 gene carry a 5- to 20-fold higher risk of developing breast or ovarian cancers. First-degree relatives who have not inherited the same familial BRCA mutation have been considered to have a considerably lower risk for breast cancer.

In 2007, a study of women who tested negative for a specific familial BRCA mutation showed they had a 2- to 5-fold increased risk of developing breast cancer; which could be considered comparable to the risk of having a BRCA mutation. According to Kurian, the results raised concerns that non-carriers might require similar screening and preventive measures as their mutation-carrying relatives, such as annual breast MRI and prophylactic surgery, and cast some doubt on the meaning of a negative BRCA test.

Kurian said that the studies had looked at women who were in cancer family clinics and compared their breast cancer risk to that of women in the general population. Women from cancer family clinics were more likely to have intensive screening, and breast cancer risks tend to be higher among close relatives of breast cancer patients than those in the general population.

The investigators took a different approach in this research by studying women with breast cancer in 3,047 families in three population-based cancer registries in Northern California (1,214), Austra
'/>"/>

Contact: Nicole Fernandes
nicole.fernandes@asco.org
571-483-1354
American Society of Clinical Oncology
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. The freshman 15 is just a myth, nationwide study reveals
2. First-of-its-kind study creates new tool for targeted cancer drug development
3. Study finds community counseling reduced the prevalence of TB on a budget
4. Practice Doesnt Always Make Perfect, Study Suggests
5. NYUCN receives $4.2 million NIH/NIDA grant to study injecting drug users in Kenya
6. NYUCN receives $2.8 million NIH/NIAID grant to study combination HIV prevention for Kenyan youth
7. Study finds no link between elderly patient activity and hospital falls
8. UT study looks at manual wheelchair use, exercise and calorie burning
9. Study finds specific gene linked to cold sore susceptibility
10. Poorer Countries Have Higher Rates of Stroke, Study Finds
11. NYUCN receives $299 thousand from NCSBN to study patient safety in nursing homes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/31/2015)... March 31, 2015 QMedET Solutions, ... 2, bringing the industry’s most advanced speech recognition ... community. Physicians can now experience the full benefits ... source, offering value-added support services that ensure successful ... , “QMedET is proud to provide Dragon Medical ...
(Date:3/31/2015)... The Oliver Law Group P.C. has launched ... client requests after Zofran lawsuits were filed in Massachusetts ... failed to warn physicians and their patients about the ... “illegally and fraudently” promoted Zofran as a treatment to ... that use from the U.S. Food and Drug Administration. ...
(Date:3/31/2015)... 31, 2015 The status of more ... discussed during a Case Management Conference scheduled to be ... New York on April 21st. According to court documents, ... litigation established for Mirena lawsuits filed on behalf of ... other serious complications related to the birth control device. ...
(Date:3/31/2015)... IL (PRWEB) March 31, 2015 Rising ... athletes have forced researchers and surgeons to better analyze ... the tissues used for repair. A recent study ... utilized a systematic review of 1,016 young, very active ... autograft tissues. , “This is the first review ...
(Date:3/31/2015)... These two automakers will address an audience of 400+ ... a shift that has become apparent in the motor ... for the insurance carriers alone. With connected car tech. ... in store for them. , Beyond more ... to their own involvement in the insurance process and ...
Breaking Medicine News(10 mins):Health News:QMedET Solutions Announces Addition of Dragon® Medical Practice Edition 2 to its Roster of Products 2Health News:Zofran Lawsuit Information Page Launched In Response To Clients Request For Information On Potential For Zofran Birth Defects, The Olive Law Group 2Health News:Zofran Lawsuit Information Page Launched In Response To Clients Request For Information On Potential For Zofran Birth Defects, The Olive Law Group 3Health News:Mirena IUD Lawsuits Move Forward as Federal Court Readies to Convene Next Case Management Conference 2Health News:Mirena IUD Lawsuits Move Forward as Federal Court Readies to Convene Next Case Management Conference 3Health News:ACL Failure Risks Increased in Young Patients Using Allografts 2Health News:TU-Automotive: Fiat and Renault-Nissan at the Centre of a Motor Insurance Evolution 2
... Donate Life California Organ & Tissue Donor Registry Reaches 2 ... Million Registrations ... Less Likely to Register, SACRAMENTO, Calif., Oct. 9 More than ... the,state,s Donate Life California Organ & Tissue Donor Registry, doubling the,state,s number ...
... Oct. 9 House Republican Whip Roy,Blunt (Mo.) ... Whip,James Clyburn (D-S.C.) yesterday suggested on CNN that ... override the president,s veto of the,SCHIP bill:, ... will be,hard-pressed to override the president,s veto of ...
... BOSTON--Like a crossword-puzzle solver who uses the letters in ... Cancer Institute and an international group of collaborators have ... breast cancer to identify a gene linked to non-hereditary ... a study posted online by the journal Nature Genetics, ...
... Pantoliano,reveals a personal history of depression and his ... in a guest blog entry, http://www.nami.org/blog published ... Pantoliano,s entry comes during Mental Illness Awareness ... opening of his latest film, CANVAS, http://www.canvasthefilm.com ...
... drinking and helped to boost abstinence, study finds , , ... to treat epileptic seizures could be added to the ... their addiction, a new study suggests. , The drug ... alcoholics stay away from heavy drinking, the study authors ...
... study is needed, and the therapy is valuable , , ... receiving androgen-deprivation therapy, a common form of hormone treatment ... face a nearly threefold higher risk of dying from ... danger results from a drop in testosterone levels that ...
Cached Medicine News:Health News:Two Million Californians Say 'Yes!' to Organ and Tissue Donation 2Health News:Two Million Californians Say 'Yes!' to Organ and Tissue Donation 3Health News:Two Million Californians Say 'Yes!' to Organ and Tissue Donation 4Health News:'Network' approach identifies potential breast cancer susceptibility gene 2Health News:'Network' approach identifies potential breast cancer susceptibility gene 3Health News:'Network' approach identifies potential breast cancer susceptibility gene 4Health News:Actor Joe Pantoliano Discloses Depression; Talks About His Latest Movie and His Sensitive Side 2Health News:Epilepsy Drug Holds Promise as Treatment for Alcoholism 2Health News:Epilepsy Drug Holds Promise as Treatment for Alcoholism 3Health News:Hormone Therapy for Prostate Cancer Linked to Heart Risks 2Health News:Hormone Therapy for Prostate Cancer Linked to Heart Risks 3Health News:Hormone Therapy for Prostate Cancer Linked to Heart Risks 4
(Date:3/31/2015)... LONDON , March 31, 2015 /PRNewswire/ ... drug discovery applications have driven the need ... far the automated segments are going to ... this research. This study provides the market ... profiling and key trends for the liquid ...
(Date:3/31/2015)... , Mar. 27, 2015 Research and Markets ... the "Intraoperative Imaging Market by Type (Intraoperative CT, ... report to their offering. The global ... CAGR of 3.5% from 2014 to 2019 ... to a number of forces that favor this market. ...
(Date:3/31/2015)... -- RnRMarketResearch.com adds "Pemphigus - Pipeline ... 68 pages with latest updates, data and information ... The report "Pemphigus - Pipeline Review, H1 2015" report provides ... Pemphigus , complete with comparative analysis at various ... action (MoA), route of administration (RoA) and molecule ...
Breaking Medicine Technology:Western European Liquid Handling Market 2Global Intraoperative Imaging (Intraoperative CT, Intraoperative MRI, Intraoperative Ultrasound) Market 2015-2019 2Pemphigus Therapeutic Development and Pipeline Review H1 2015 2Pemphigus Therapeutic Development and Pipeline Review H1 2015 3Pemphigus Therapeutic Development and Pipeline Review H1 2015 4
... 22, 2011 ResearchDx announced today the official ... CDO. Recent FDA initiatives, such ... Co-Development Concept Paper, have spurred biopharmaceutical companies, interest ... companion diagnostics. The traditional Contract Research Organization (CRO), ...
... OMER ) today announced that its exclusive license to ... been amended to include addiction and compulsive disorders in the ... Company,s discovery of a previously unknown link between PDE7 and ... it also is the first to link PDE7 to any ...
Cached Medicine Technology:ResearchDx Launches Contract Diagnostics Organization (CDO) 2Omeros Announces Expansion of Exclusive License to PDE7 Inhibitors from Daiichi Sankyo 2Omeros Announces Expansion of Exclusive License to PDE7 Inhibitors from Daiichi Sankyo 3Omeros Announces Expansion of Exclusive License to PDE7 Inhibitors from Daiichi Sankyo 4
... Agarose with low electroendosmosis ... most DNA/RNA applications. If ... to be used as ... ligase and restriction endonucleases, ...
Excellent multi purpose agarose Nuclease-free, Gel point (1.5%): 36 1.5 C, EEO: 0.05-0.13 Gel strength (1%): > 1200 g/cm 2 ....
... standard gelling temperature, high gel strength agarose ... bp. This Genetic Technology Grade™ (GTG) agarose ... DNA recovered from SeaKem GTG Agarose gels ... GTG Agarose is extensively performance tested to ...
This agarose provides superior resolution of small PCR fragments and primers at lower concentrations than standard agaroses. A 3% gel clearly resolves a 10 bp ladder, and a 4% gel approaches the reso...
Medicine Products: