Navigation Links
Study shows no increased risk of breast cancer for non-carriers in families with BRCA gene mutation
Date:10/31/2011

," said study first author Allison Kurian, MD, assistant professor of medicine and health research and policy at Stanford University School of Medicine. "One strength of the current study is the control women it used as a yardstick for comparing the breast cancer incidence in non-carriers of family-specific mutations. The control women were also relatives of breast cancer patients, but of patients without mutations. This is a more appropriate yardstick than average risk in the general population, since close relatives of all breast cancer patients have somewhat higher than average risks."

Women who inherit a mutation in the BRCA1 or BRCA2 gene carry a 5- to 20-fold higher risk of developing breast or ovarian cancers. First-degree relatives who have not inherited the same familial BRCA mutation have been considered to have a considerably lower risk for breast cancer.

In 2007, a study of women who tested negative for a specific familial BRCA mutation showed they had a 2- to 5-fold increased risk of developing breast cancer; which could be considered comparable to the risk of having a BRCA mutation. According to Kurian, the results raised concerns that non-carriers might require similar screening and preventive measures as their mutation-carrying relatives, such as annual breast MRI and prophylactic surgery, and cast some doubt on the meaning of a negative BRCA test.

Kurian said that the studies had looked at women who were in cancer family clinics and compared their breast cancer risk to that of women in the general population. Women from cancer family clinics were more likely to have intensive screening, and breast cancer risks tend to be higher among close relatives of breast cancer patients than those in the general population.

The investigators took a different approach in this research by studying women with breast cancer in 3,047 families in three population-based cancer registries in Northern California (1,214), Austra
'/>"/>

Contact: Nicole Fernandes
nicole.fernandes@asco.org
571-483-1354
American Society of Clinical Oncology
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. The freshman 15 is just a myth, nationwide study reveals
2. First-of-its-kind study creates new tool for targeted cancer drug development
3. Study finds community counseling reduced the prevalence of TB on a budget
4. Practice Doesnt Always Make Perfect, Study Suggests
5. NYUCN receives $4.2 million NIH/NIDA grant to study injecting drug users in Kenya
6. NYUCN receives $2.8 million NIH/NIAID grant to study combination HIV prevention for Kenyan youth
7. Study finds no link between elderly patient activity and hospital falls
8. UT study looks at manual wheelchair use, exercise and calorie burning
9. Study finds specific gene linked to cold sore susceptibility
10. Poorer Countries Have Higher Rates of Stroke, Study Finds
11. NYUCN receives $299 thousand from NCSBN to study patient safety in nursing homes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2015)... ... August 28, 2015 , ... CARF ... its adolescent residential, counseling, day treatment and intensive family based services. , By ... for quality and its pursuit of excellence. As a nonprofit charity for more ...
(Date:8/28/2015)... ... 2015 , ... Northridge dentists Dr. Elyson and Dr. Assili are ... can currently receive a one hour treatment of this teeth whitening option. Zoom ... number of unique features that can turn teeth up to nine shades whiter. Effective ...
(Date:8/28/2015)... , ... August 28, 2015 , ... ... is dedicated to distributing health information technology innovation to transform quality and efficiency ... of the survey will be de-identified and aggregated before being publicly shared to ...
(Date:8/28/2015)... ... August 28, 2015 , ... ... top 5 millionaire dating sites . According to the listings, MillionaireMatch.com ... best in this category. , A spokesperson of Top5MillionaireDatingSites.com said, “This ...
(Date:8/28/2015)... ... August 28, 2015 , ... A complimentary webinar offered by healthcare consulting and ... (CMS) proposal to mandate bundled payments through the Comprehensive Care for Joint ... Day: Comprehensive Care for Joint Replacement,” takes place at 12 noon EDT on Wednesday, ...
Breaking Medicine News(10 mins):Health News:West Ridge Academy Awarded CARF Three-Year Accrediation 2Health News:Northridge Dentists Dr. Elyson and Dr. Assili Now Offer a Special Promotion on Zoom Teeth Whitening 2Health News:WEDI's The Sullivan Institute for Healthcare Innovation Releases Gaps in Care Survey 2Health News:Top5MillionaireDatingSites.com Publishes Its First List of Reviews of the Best Millionaire Dating Sites 2Health News:PYA Offers Complimentary CCJR Webina — Game On 2Health News:PYA Offers Complimentary CCJR Webina — Game On 3
... today announced that Glenn A. Oclassen, President & Chief ... Development in a,Changed Environment" at the RBC Capital Markets ... Times Square on Thursday, December 13, 2007,at 10:00 AM ... by Ken Trbovich, Vice,President, Capital Markets at RBC, and ...
... Worsening State Budget Picture, Ongoing Medicaid,Funding Crisis Cited, ... Payment Advisory Commission,s (MedPAC) draft recommendation that,skilled nursing ... for 2009, the Alliance for Quality Nursing Home ... the mark" in terms of,providing Congress with the ...
... or more servings of green salad a week and working ... nonsmokers alike may be able to substantially reduce the risk ... Texas M. D. Anderson Cancer Center. , "This is the ... and physical activity on the possibility of developing lung cancer," ...
... Dec 7 Bond,Laboratories, Inc. (OTC Bulletin Board: BNDB), ... to file with the NASD to implement,a 2-for-1 forward ... shareholders as of the record date will receive,two (2) ... own. For,example, shareholders owning 5,000 shares prior to the ...
... her 2002 book "Growing,Up X," Ilyasah Shabazz describes growing up ... recently, Ms. Shabazz has delved deeper,into her family tree, discovering ... December 9 - 14, Ms. Shabazz will visit her ancestral ... hosted by Malaria No More, an,organization working to end malaria-related ...
... The Board of Directors of the,Pittsburgh Life Sciences ... company formation and business growth,services to the region,s ... nomination of Dr. D. Lansing Taylor as the ... In making the announcement, outgoing Co-Chairs Mark Nordenberg ...
Cached Medicine News:Health News:Transcept Pharmaceuticals to Present at RBC Capital Markets 2007 Healthcare Conference 2Health News:MedPAC Again Fails to Evaluate Overall Economic Conditions in Assessing SNF Funding Requirements 2Health News:MedPAC Again Fails to Evaluate Overall Economic Conditions in Assessing SNF Funding Requirements 3Health News:M. D. Anderson research links diet, gardening and lung cancer risk 2Health News:Malcolm X Daughter Travels to Ancestral Home; Joins Muslim-American Leadership to Fight Malaria in Mali 2Health News:The Pittsburgh Life Sciences Greenhouse Announces New Chairman of the Board 2Health News:The Pittsburgh Life Sciences Greenhouse Announces New Chairman of the Board 3
(Date:8/28/2015)... Denmark and ATLANTA , ... 2015 the US Food and Drug Administration (FDA) cleared the ... Disorder in adult patients who have failed to receive satisfactory ... is a non-invasive technique for stimulating neural tissue in the ... Depressive Disorder. The procedure has been proven safe and effective ...
(Date:8/28/2015)... , August 28, 2015 Insights- ... seamlessly connects people, technologies and care protoc ols across ... and the cost of healthcare delivery   ... presence at  ESC Congress 2015 , where the company is ... EchoNavigator and IntelliSpace Cardiovascular, that connect people and technology with ...
(Date:8/27/2015)... -- Biosimilars are not generics and the Biologics ... Drug Administration (FDA) for recognizing that each biosimilar ... issued today. The FDA,s draft guidance on nonproprietary ... for biological products to bear a nonproprietary name ... the agency,s thinking that "there is a need ...
Breaking Medicine Technology:Therapy System for Treating Major Depressive Disorder Receives FDA Clearance 2Therapy System for Treating Major Depressive Disorder Receives FDA Clearance 3Philips Showcases New Integrated Cardiology Solutions to Advance Minimally Invasive Procedures at ESC Congress 2015 2Philips Showcases New Integrated Cardiology Solutions to Advance Minimally Invasive Procedures at ESC Congress 2015 3Philips Showcases New Integrated Cardiology Solutions to Advance Minimally Invasive Procedures at ESC Congress 2015 4Biologics Prescribers Collaborative (BPC) Statement on FDA Draft Guidance entitled "Nonproprietary Naming of Biological Products" 2
... BOZEMAN, Mont., Sept 8 LigoCyte Pharmaceuticals, Inc. ... clinical trial of its norovirus vaccine. The Phase I/II ... nasally-delivered, dry powder vaccine in healthy adults. The study will ... by including a live virus challenge of subjects that have ...
... , , , MORGANTON, W.Va., ... also do better at overcoming pain and depression than people treated ... the National Institutes of Health shows. , , ... journal Spine, showed lifted mood, less pain and improved function in ...
Cached Medicine Technology:LigoCyte Pharmaceuticals Initiates a Randomized, Double Blind, Placebo Controlled Norovirus Vaccine Study Including Live Virus Challenge 2LigoCyte Pharmaceuticals Initiates a Randomized, Double Blind, Placebo Controlled Norovirus Vaccine Study Including Live Virus Challenge 3Yoga Benefits Back-Pain Patients 2
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: