Navigation Links
Study: HIV Infection Does Not Adversely Affect Outcomes of Liver Transplantation for Hepatocellular Carcinoma
Date:5/10/2013

Durham, NC (PRWEB) May 10, 2013

Liver transplantation for hepatocellular carcinoma (HCC) is feasible for HIV-infected patients, with no differences in post-transplant survival or HCC recurrence rates compared with liver transplantation for HCC in HIV-uninfected patients. The study, published in The Oncologist, was led by Dr. Fabrizio Di Benedetto, MD, PhD, Associate Professor of Surgery, University of Modena and Reggio Emilia, Modena, Italy, and represents the largest multicenter study of liver transplant for HCC in HIV-infected patients to date.

Patients infected with HIV experience a more aggressive course of HCC, in part due to the tumor-enhancing effects of HIV proteins, including increased growth signaling and diminished antitumor immune response. Moreover, as highly active antiretroviral therapy (HAART) prolongs the life expectancy of HIV-infected patients, the progression of underlying liver disease toward HCC is increasingly a major cause of morbidity and mortality in this patient population. Liver transplantation for HCC in HIV-infected patients is a recent indication, and its viability as a treatment option has been a matter of debate.

In the current study, researchers evaluated post-transplant outcomes in 30 HIV-positive patients and 125 HIV-uninfected patients who underwent liver transplantation for HCC at three transplantation centers in northern Italy between 2004 and 2009. Two patients in the HIV-positive cohort (6.7%) and 18 uninfected patients (14.4%) experienced a recurrence of HCC during the follow-up period of approximately 32 months (p = .15). Overall survival was similar for HIV-infected and -uninfected patients at 1 year (77% vs. 86.4%) and 3 years (65% vs. 70%), respectively, after liver transplantation (p = .32).

“The key message of this study is that liver transplantation is a valid option for HCC treatment in HIV-infected patients,” Dr. Di Benedetto and colleagues wrote. “We sugg
'/>"/>

Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Page: 1 2 3

Related medicine news :

1. Penn pilot study: Group of Bradford Co, Pa. residents concerned about health effects of hydrofracking
2. Great HealthWorks, Inc., makers of Omega XL, Report New Independent Study: Omega-3 DHA Protects Against Liver Disease
3. New IU study: How often is more important than why when describing breakups
4. Study: Physicians less likely to bond with overweight patients
5. The doctor wont see you now? Study: US facing a neurologist shortage
6. Study: Dental bib clips can harbor oral and skin bacteria even after disinfection
7. Doctors Health Press Reports on Study: Apples, Pears, Leafy Green Vegetables Lower Risk of Stroke
8. Bel Marra Health Reports on a New Harvard Study: Abuse of Prescription Drugs and Alcohol on the Steady Upswing
9. Study: Hospital infections in cancer patients climbed, deaths declined
10. Cedars-Sinai study: Obesity may be linked to microorganisms living in the gut
11. Study: Research reveals protective properties of influenza vaccines
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/26/2015)... 2015 Let’s not lose focus of ... are today’s traffic magnets. Three out of 4 consumers ... their produce department, according to a Packaged Facts survey. ... are looking to add more fruits and vegetables to ... Day is April 2. As featured in the Chase’s ...
(Date:3/26/2015)... North American Seminars launches it new mobile ... providing information regarding OT PT continuing education courses to ... a leader in live hands PT continuing education ... and online continuing education courses. , Featured ... Master Clinicians Approach to Advanced Concepts in Examination and ...
(Date:3/26/2015)... 26, 2015 Florida Hospital teamed up with ... Your Health campaign and live Dr. Oz event, which took ... 21st. More than a thousand people came out to see ... , The world renowned cardiothoracic surgeon and Emmy award ... Hurtado and a panel of experts for the live health ...
(Date:3/26/2015)... March 26, 2015 The Baruch S. ... team of nationally renowned scientists to focus exclusively on ... move that nearly triples its research capacity and has ... on hepatitis B and liver cancer in the United ... Jinhong Chang, Ju Tao Guo and Ying-Hsiu Su – ...
(Date:3/26/2015)... March 26, 2015 “The SWEET Act is ... healthy options more available and help parents who are working ... is a reasonable approach to support public health, and we ... issue for the health of all families,” said Dr. Jane ... Health on the introduction of the Sugar-Sweetened Beverage Tax (SWEET) ...
Breaking Medicine News(10 mins):Health News:North American Seminars Launches Healthclick.com, a New Mobile Ready Website, Providing CME Course Information to PT, PTA, OT and ATC's 2Health News:North American Seminars Launches Healthclick.com, a New Mobile Ready Website, Providing CME Course Information to PT, PTA, OT and ATC's 3Health News:Florida Hospital Welcome Dr. Oz to Tampa and Invites the Community to Attend Educational Seminars Hosted by Florida Hospital Physicians 2Health News:Florida Hospital Welcome Dr. Oz to Tampa and Invites the Community to Attend Educational Seminars Hosted by Florida Hospital Physicians 3Health News:Baruch S. Blumberg Institute Recruits World-Class Hepatitis B Scientists 2Health News:Baruch S. Blumberg Institute Recruits World-Class Hepatitis B Scientists 3Health News:Baruch S. Blumberg Institute Recruits World-Class Hepatitis B Scientists 4Health News:National Alliance for Hispanic Health Statement on Introduction of SWEET Act in 114th Congress 2
... ... ... of complex government regulation some of the stand-out questions include:, , ,   ... How are these standards impacted by the convergence of media and conflation of traditional media ...
... , ... ... ... ...
... ... ... ... ...
... study has confirmed earlier study results that 400 ... efficacy and tolerability for patients with uncontrolled partial-onset ... additional benefit for some patients. Researchers from the ... Center, Thomas Jefferson University Medical School, Arkansas Epilepsy ...
... The maximal standardized uptake value (called SUVmax) measured ... tumor in head and neck squamous cell carcinoma ... disease-specific survival, overall survival and disease-free survival, while ... distant metastasis, according to a study presented at ...
... Natural defense against the disease could be more common than ... The seemingly miraculous recovery from rabies of a 17-year-old Texas ... is leaving doctors scratching their heads and wondering if such ... case "suggests the rare possibility that abortive rabies can occur ...
Cached Medicine News:Health News:Alan Chapell, President of Chapell & Associates to Deliver Keynote at the Next AdMonsters US Leadership Forum 2Health News:Alan Chapell, President of Chapell & Associates to Deliver Keynote at the Next AdMonsters US Leadership Forum 3Health News:Highmark Inc. Prepares Now for the Diversity Boom Ahead 2Health News:Highmark Inc. Prepares Now for the Diversity Boom Ahead 3Health News:Highmark Inc. Prepares Now for the Diversity Boom Ahead 4Health News:Providence Service Corporation to Present at the RBC Capital Markets Healthcare Conference on Tuesday, March 2nd 2Health News:Providence Service Corporation to Present at the RBC Capital Markets Healthcare Conference on Tuesday, March 2nd 3Health News:Providence Service Corporation to Present at the RBC Capital Markets Healthcare Conference on Tuesday, March 2nd 4Health News:Lacosamide validated as promising therapy for uncontrolled partial-onset seizures 2Health News:Lacosamide validated as promising therapy for uncontrolled partial-onset seizures 3Health News:Pretreatment SUV associated with head and neck cancer treatment outcomes, may help decide treatment plans 2Health News:Texas Girl Recovers From Rabies Without Intensive Care 2
(Date:3/26/2015)... Columbia, March 26, 2015  OncoGenex Pharmaceuticals, Inc. ... of clinical developments and announced fourth quarter and ... Clinical Developments and Anticipated Near-term MilestonesCustirsen ... agreed to negotiate the termination of their collaboration ... the final termination agreement are ongoing. , ...
(Date:3/26/2015)... , March 26, 2015  CCS Medical ... home medical supplies for patients with chronic conditions, ... and Chief Executive Officer, effective March 23.  Mr. ... telehealth company, where he was President of Operations. ... was President and Executive Vice President of Operations ...
(Date:3/26/2015)... , March 26, 2015 Zimmer Holdings, Inc. ... new mobile app designed to serve as a feature-rich resource ... product. For those experiencing knee pain, the ... about the causes of knee pain and helps them understand ... a safe and simple non-surgical treatment option. For those who ...
Breaking Medicine Technology:OncoGenex Pharmaceuticals, Inc. Reports Financial Results for Fourth Quarter and Year End 2014 2OncoGenex Pharmaceuticals, Inc. Reports Financial Results for Fourth Quarter and Year End 2014 3OncoGenex Pharmaceuticals, Inc. Reports Financial Results for Fourth Quarter and Year End 2014 4OncoGenex Pharmaceuticals, Inc. Reports Financial Results for Fourth Quarter and Year End 2014 5OncoGenex Pharmaceuticals, Inc. Reports Financial Results for Fourth Quarter and Year End 2014 6OncoGenex Pharmaceuticals, Inc. Reports Financial Results for Fourth Quarter and Year End 2014 7OncoGenex Pharmaceuticals, Inc. Reports Financial Results for Fourth Quarter and Year End 2014 8CCS Medical Team Hires Industry Operator Rodney Carson as CEO 2Zimmer Launches New Patient Education And Engagement Mobile App For Gel-One Hyaluronate 2
... VSCP ), a provider of quantitative imaging for clinical ... 30, 2010 exceeded $3.5 million, representing a greater than 25% ... than 9% growth over the preceding quarter ended June 30, ... September 30, 2010 compared to the same period in 2009. ...
... Amex: PTN ) announced that it will be ... October 6, 2010 at 8:00 AM PT.  Hosted by the ... will take place October 5-6 at the Palace Hotel in ... and Chief Executive Officer of Palatin Technologies, will provide an ...
Cached Medicine Technology:VirtualScopics Revenues Hit Another Quarterly Record 2VirtualScopics Revenues Hit Another Quarterly Record 3
... Cochrane Reviews enable all those involved with ... with the very latest evidence in their ... becomes harder each year as the volume ... problem by delivering the best single source ...
Muscles Anatomy Flash Cards uses the time tested content and images from BryanEdwards.com....
Pocket Sports Medicine is the result of a collaboration between outstanding Editors and Contributors. The program covers the field so that both specialists and general orthopedists will find expert g...
... Cochrane Reviews enable all those involved with ... with the very latest evidence in their ... becomes harder each year as the volume ... problem by delivering the best single source ...
Medicine Products: