Navigation Links
Studies challenge standards to improve treatment outcomes for patients with clotting disorders
Date:12/8/2012

tract 4]

In the first randomized clinical trial assessing the proper target hematocrit level, or percentage of red blood cells that should be maintained in patients with polycythemia vera (PV), researchers have concluded that the current recommendation to maintain a hematocrit level of less than 45 percent is associated with a lower risk of thrombosis compared with a less aggressive treatment strategy of maintaining a hematocrit level between 45 and 50 percent.

PV is a rare blood disorder that causes the bone marrow to produce too many red blood cells, making the blood much thicker.This can dramatically increase the risk of blood clots such as deep-vein thrombosis (DVT, a blood clot that forms in a vein deep in the legs) or pulmonary embolism (PE, a blood clot in the lung) and cardiovascular events such as heart attack or stroke. Because thrombosis is the most common cause of death in patients with PV, prompt diagnosis and treatment to reduce the thickness of the blood is critical.

Patients with PV usually have elevated hematocrit levels (approximately 50 to 70%, compared with less than 50% in the general population), which puts them at a higher risk of suffering heart attacks, strokes, and DVT/PE than the general population. In order to reduce this risk, a hematocrit level of less than 45 percent is recommended and initially maintained through phlebotomies. If the hematocrit level cannot be reduced through multiple phlebotomies or disease progression is documented, patients receive hydroxyurea or chemotherapy to eliminate the excess red blood cells. While these two treatment strategies have become widely accepted for PV, until recently no prospective randomized clinical trial has confirmed whether tight control of hematocrit levels below 45 percent successfully prevents or reduces blood clots in patients with PV.

In order to assess the efficacy and safety of maintaining a hematocrit level of lower than 45 percent versus a mo
'/>"/>

Contact: Andrea Slesinski
aslesinski@hematology.org
614-352-5096
American Society of Hematology
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. Studies assess genetics, modified treatment to improve outcomes, reduce toxicity
2. John Theurer Cancer Center to present 37 studies at the 2012 ASH Annual Meeting
3. Benefit6 Whole Body Protection, a New Product by I Do Strive LLC, Provides Increased Energy Production According to Recent Studies
4. Sharp spike in computer-related injuries predicted for medical workers, find studies
5. Analysis of conflicting fish oil studies finds that omega-3 fatty acids still matter
6. Studies from 2012 Quality Care Symposium highlight findings in improving quality of cancer care
7. New studies show effects of mammography guideline changes
8. 2 NIH studies show power of epidemiology research; Underscore need to address health disparities
9. Scripps studies show community-based diabetes programs are key to lowered costs and improved care
10. Cancer Drug Reduced Relapses in MS Patients: Studies
11. University of Houston India Studies Program presents Circuits of Empire: India as Metropole
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/18/2014)... Johns Hopkins University School of Medicine researchers have been ... for diabetes, Novo Nordisk announced this month. Of the ... and Obesity Biologics Science Forum Program, only four projects ... Hopkins researchers. They are Jonathan Powell, M.D., Ph.D.; G. ... , Jonathan Powell, a professor of oncology, will use ...
(Date:4/18/2014)... 2014) ― A new study in the American ... health-related Google searches reveals a recurring pattern that could ... , Investigators from San Diego State University, the Santa ... analyzed "healthy" Google searches (searches that included the term ... in the U.S. from 2005 to 2012. They found ...
(Date:4/17/2014)... of chronic inflammation in non-cancerous prostate tissue may have ... than those with no inflammation, according to results of ... Hopkins Kimmel Cancer Center. , The link between persistent ... so-called high-grade prostate cancer those with a Gleason ... of the most aggressive and rapidly growing prostate cancers. ...
(Date:4/17/2014)... According to a study published today in PLOS ... world where malaria is common can mount an immune ... them to avoid repeated bouts of high fever and ... in their bloodstream. The findings may help researchers develop ... by the malaria parasite. , Each year, approximately 200 ...
(Date:4/17/2014)... a review published in the April issue of ... Feinstein Institute for Medical Research, says it,s time to ... approach to treating sepsis, which kills millions worldwide ... occurs when molecules released into the bloodstream to fight ... Inflammation is necessary for maintaining good health without ...
Breaking Medicine News(10 mins):Health News:New research shows people are thinking about their health early in the week 2Health News:Chronic inflammation linked to 'high-grade' prostate cancer 2Health News:Chronic inflammation linked to 'high-grade' prostate cancer 3Health News:Study sheds light on how the immune system protects children from malaria 2Health News:Feinstein Institute researcher publishes new perspective on sepsis 2
... value in health care: What should we pay for and ... health care should be balanced against various realities--including the effectiveness ... Especially in a depressed economy, questions about value in health ... reform debates. , In a commentary published in Health ...
... 26 Krause, Kalfayan, Benink & Slavens, LLP filed ... Court on behalf of a putative class of California ... years, Scripps Health billed for medical services after their ... emergency medical bills. The lawsuit alleges that ...
... COLUMBUS, Ga., Jan. 26 Aflac Incorporated,announced today that ... will webcast a conference call scheduled for 9:00 a.m. ... in addition to the previously,announced fourth quarter webcast meeting ... During the morning teleconference on February 3, ...
... For Needed Enforcement of Canon 915; Withholding Eucharist From ... American Life League executive director Shaun Kenney issued the ... Pelosi,s interview with ABC News on Sunday. Rep. Pelosi ... in the economic stimulus package would "reduce costs to ...
... on interoperability specifications from the Healthcare Information Technology Standards Panel ... ... Chicago (Vocus) January 26, 2009 -- With the economic ... domestic priorities identified in Tuesday,s inaugural address, with President Obama ...
... United American Healthcare,Corporation (Nasdaq: UAHC ), a ... financial results for the second fiscal,quarter ended December 31, ... The Company will host a conference call at 4:30 ... , Participation in the call,s ...
Cached Medicine News:Health News:Can payment and other innovations improve the quality and value of health care? 2Health News:KRAUSE, KALFAYAN, BENINK & SLAVENS, LLP, Announces Filing a Class Action Lawsuit Against Scripps Health, et al. 2Health News:Aflac Announces Additional Teleconference Webcast 2Health News:American Life League Statement on Pelosi's State-Enforced War on Preborn Babies 2Health News:Achieving Interconnected Healthcare through HITSP Real-Life Scenarios 2Health News:Achieving Interconnected Healthcare through HITSP Real-Life Scenarios 3Health News:Achieving Interconnected Healthcare through HITSP Real-Life Scenarios 4Health News:Achieving Interconnected Healthcare through HITSP Real-Life Scenarios 5Health News:Achieving Interconnected Healthcare through HITSP Real-Life Scenarios 6Health News:United American Healthcare Corporation to Host Fiscal 2009 Second Quarter Results Conference Call February 5th 2
(Date:1/15/2014)... , Jan. 15, 2014  Valeant Pharmaceuticals International, Inc. (NYSE: ... the applicable waiting period under the Hart-Scott-Rodino Antitrust Improvements ... announced tender offer by its indirect wholly-owned subsidiary, Sapphire ... of common stock of Solta Medical, Inc. (NASDAQ: ...
(Date:1/15/2014)... , Jan. 15, 2014  Zafgen, Inc., a leading ... of severely obese patients, today announced initial results ... selective inhibitor of methionine aminopeptidase 2 (MetAP2), in ... of genetic obesity.  These results showed improvements in ...
(Date:1/14/2014)... , Jan. 14, 2014  Luminex Corporation (Nasdaq: LMNX ... the fourth quarter of 2013 on Monday, February 3, 2014. ... after the close of trading. (Logo: ... to discuss the operating highlights and financial results for the ...
Breaking Medicine Technology:Valeant Pharmaceuticals Announces Receipt Of Antitrust Clearance For Its Previously Announced Acquisition Of Solta Medical, Inc. 2Valeant Pharmaceuticals Announces Receipt Of Antitrust Clearance For Its Previously Announced Acquisition Of Solta Medical, Inc. 3Zafgen Announces Initial Results from Phase 2a Study of Beloranib in Patients with Prader-Willi Syndrome 2Zafgen Announces Initial Results from Phase 2a Study of Beloranib in Patients with Prader-Willi Syndrome 3Zafgen Announces Initial Results from Phase 2a Study of Beloranib in Patients with Prader-Willi Syndrome 4Luminex Corporation Fourth Quarter Earnings Release Scheduled for February 3, 2014 2Luminex Corporation Fourth Quarter Earnings Release Scheduled for February 3, 2014 3
... data, competitor focus, and new drug-eluting technologies to drive ... according to Millennium Research Group WALTHAM, Mass., May ... European Markets for Peripheral Vascular (PV) Devices 2009 ... that treat lower extremity peripheral artery disease in Europe ...
... Results and additional analyses from the Phase II portion ... drug relaxin for the treatment of acute heart failure ... annual meeting of the Heart Failure Association of the ... Metra, M.D., professor of cardiology at the University of ...
Cached Medicine Technology:Lower Extremity Peripheral Vascular Stent and Balloon Catheter Markets to Exceed $180 Million in Europe by 2013 2Lower Extremity Peripheral Vascular Stent and Balloon Catheter Markets to Exceed $180 Million in Europe by 2013 3Results and Additional Analyses From Efficacy and Safety Study of Corthera's Relaxin in Acute Heart Failure to be Presented at Heart Failure Congress 2009 2
... with 24-well x 0.2ml sub-ambient block and ... thermistor) Heating rates: up to 3C/second; Accurate ... Excellent uniformity: better than 0.5C within 15 ... programming: directory program storage of up to ...
... maximizes what a thermal cycler can do ... formats, an easy graphic interface, and best ... PCR. The iCycler thermal cycler will raise ... can do for you.,, iCycler Thermal Cycler ...
Contains: Card, cabling and instructions to remotely access a RoboCycler® instrument from a PC or Macintosh® computer...
... RoboCycler Gradient 40 or 96 temperature cyclers, the ... linear temperature range of up to 14 or ... with a temperature difference of up to 2C ... you can test up to 12 different annealing ...
Medicine Products: