Navigation Links
Stroke therapy window might be extended past nine hours for some
Date:2/9/2009

OAK BROOK, Ill. (Feb. 9, 2009) Some patients who suffer a stroke as a result of a blockage in an artery in the brain may benefit from a clot-busting drug nine or more hours after the onset of symptoms. The findings are published in the online edition of Radiology.

"Stroke is the third leading cause of death in the U.S.," said the study's lead author, William A. Copen, M.D., Director of Advanced Magnetic Resonance Neuroimaging at Massachusetts General Hospital (MGH) in Boston. "Every hour that we can add to the treatment window would allow vastly more stroke patients to be treated with potentially life-saving therapy."

The most common type of stroke is called ischemic stroke. These strokes occur when a blood clot blocks a blood vessel supplying blood to the brain. Some ischemic strokes can be treated with thrombolytic, or clot-busting, therapy using tissue plasminogen activator (t-PA), which helps dissolve the blockage. However, the window of opportunity to safely administer the medication is generally considered to be just three hours. Because few patients get to the hospital to be diagnosed and treated within that time frame, fewer than seven percent of patients receive the drug.

In this retrospective study, researchers analyzed the test results of 109 ischemic stroke patients at MGH. The testing methods included two different MRI scanning techniques: perfusion MRI, which measures blood flow in the brain, and diffusion MRI, which measures the movement of water molecules in tissue.

"Comparing the lesions that we see in these two MR images reveals which areas of the brain are threatened by a lack of blood flow, but could still be salvageable," Dr. Copen said. "A mismatch between the lesions suggests that a patient might still benefit from thrombolytic therapy."

In the study, most patients with blockage in a proximal artery, close to the base of the brain, continued to demonstrate a diffusion-perfusion mismatc
'/>"/>

Contact: Linda Brooks
lbrooks@rsna.org
630-590-7762
Radiological Society of North America
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Study, meta-analysis examine factors associated with death from heatstroke
2. High alcohol consumption increases stroke risk among Chinese men
3. Heavy Drinking Boosts Stroke Risk for Chinese Men
4. High alcohol consumption increases stroke risk, Tulane study says
5. Broad-based group of physicians calls for improvement in stroke treatment
6. Continued Statin Use Boosts Post-Stroke Outcomes
7. U.S. Initiative Seeks to Boost Hispanic Stroke Awareness
8. Stopping Statins After Stroke Doubles Death Risk
9. Can brain-injured, partially-blind stroke patients regain some of their lost vision?
10. REACH Registry Highlights That Patients With Peripheral Arterial Disease (PAD) Suffer High Rates of Heart Attack, Stroke, Hospitalization, and Death
11. Link Between Air Pollution, Stroke Gets Clearer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2014)... NEW YORK, NY (April 16, 2014) The cause ... but a new study proposes that neurons may be ... own immune system, similar to the way autoimmune diseases ... attack the body,s cells. The study was published April ... is a new, and likely controversial, idea in Parkinson,s ...
(Date:4/17/2014)... (SACRAMENTO, Calif.) An international team led by researchers ... protein complex, which plays a key role in cell ... process. This is the first time the complex has ... could make cyclin B1/Cdk1 an excellent target to control ... medicine. The research was published online today in the ...
(Date:4/17/2014)... WINSTON-SALEM, N.C. April 17, 2014 Meaningful ... from advanced cancer of the abdomen when treated ... HIPEC, according to a first-of-its-size analysis by physicians ... Forest Baptist has the largest reported, single-center experience ... Edward A. Levine, M.D., and analysis of 20 ...
(Date:4/17/2014)... 17, 2014 Giving patients adrenaline after they suffer a ... their prospects of surviving long-term, according to new research ... of patients who have a cardiac arrest get adrenaline, ... arrest for decades," said Dr. Steve Lin, an emergency ... despite advances in medical treatment, long-term survival rates of ...
(Date:4/16/2014)... Ariz. April 15, 2014 The Translational Genomics ... at their annual Founders Dinner for their support of ... event took place March 28 in Scottsdale. , Catherine ... Ivy Foundation, received TGen,s John S. McCain Leadership Award, ...
Breaking Medicine News(10 mins):Health News:Is Parkinson's an autoimmune disease? 2Health News:Dual role: Key cell division proteins also power up mitochondria 2Health News:20 years of data shows treatment technique improvement for advanced abdominal cancer 2Health News:Adrenaline does little to increase patient's survival after cardiac arrest 2Health News:TGen honors Catherine Ivy and Craig Jackson with Leadership; Collaborative Spirit awards 2
... students will convene for one week in Adelaide from ... the Australian Medical Students Association (AMSA). ... this annual event brings students from each of Australias ... a rousing week of activities. ,The Convention ...
... the risk of developing venous thrombo-embolism (VTE) approximately doubles after ... a research study of global hazards of travel, the WHO, ... seated and immobile for more than four hours remains relatively ... the study, the two most common manifestations of VTE are ...
... happy about the significant improvement in containing the bird ... a new virus carried by bats that can cause ... veterinary experts have singled out Indonesia, Egypt and Nigeria ... is particularly worrisome. ,FAO's Chief Veterinary Officer ...
... capacity and inflammation in 1,000 adults aged between 26 ... at the amount of C-reactive protein (CRP), an inflammatory ... were found in the blood of those with smaller ... for inflammation have previously been found in the blood ...
... at time behind bars when he faces a court on Tuesday, ... drugs in early May after the cops stopped his Jaguar in ... for having crack cocaine and cannabis. He was later released on ... have now been added to Doherty's charges, and he is now ...
... hunks chilling out on a hot summer day with a ... adults, but they're also having an impact on teens, ... is based on a study conducted by researchers at the ... adolescents attending schools in neighbourhoods where alcohol ads litter the ...
Cached Medicine News:Health News:Thrombosis Risk in Travel Lasting Over Four Hours is Higher: WHO 2Health News:Avian Flu Seen in Others Birds too 2Health News:Avian Flu Seen in Others Birds too 3Health News:Outdoor Alcohol Ads Boost Urge to Drink in Young Teens 2
(Date:1/15/2014)... , Jan. 15, 2014  Novation, the leading health ... several new IT value-added reseller (VAR) national contracts that ... goods and services at lower costs. These include manufacturer ... such as initiative assistance and ongoing IT consulting support. ...
(Date:1/15/2014)... DUBLIN , January 15, 2014 Shire plc ... waived the Office of Fair Trading (OFT) approval condition to the ... Incorporated (NASDAQ: VPHM).   As a result of the ... Shire expects to complete the tender offer on January 24, 2014 ...
(Date:1/15/2014)... Ky. , Jan. 15, 2014  Manufacturers, suppliers ... must be able to protect their most important ... http://photos.prnewswire.com/prnh/20130716/CL46586LOGO ) Because of ... it steadfastly remains one of the most litigious ...
Breaking Medicine Technology:New Novation Information Technology VAR Contracts Offer Significant Savings to Hospitals 2Shire Waives OFT Condition Relating to the Acquisition of ViroPharma Inc. 2Shire Waives OFT Condition Relating to the Acquisition of ViroPharma Inc. 3Intellectual Property Insurance for Medical-related Products and Services 2
... (Nasdaq: CRDC ) today announced that it has ... loan commitment with Century Medical, allowing Cardica to draw the ... commitment from Century. "We are pleased to have ... agreement, bringing us access to additional capital as we continue ...
... Sept. 22, 2011 BioLineRx Ltd. (NASDAQ: ... announced that it has retained KCSA Strategic Communications, a ... investor relations program. KCSA intends to ... increase awareness of BioLineRx among the U.S. investment community. ...
Cached Medicine Technology:Cardica Achieves Milestone Under Century Distribution Agreement 2BioLineRx Ltd. Retains KCSA Strategic Communications as U.S. Investor Relations Counsel 2BioLineRx Ltd. Retains KCSA Strategic Communications as U.S. Investor Relations Counsel 3
... for Unparalleled Comfort Pick one of our ... Notice the trigger and ejector positionsright where they ... pipettors are ergonomically designed to help avoid repetitive ... Productivity In The Palm Of Your Hand ...
... Design for Unparalleled Comfort Pick one of ... balance. Notice the trigger and ejector positionsright where ... our pipettors are ergonomically designed to help avoid ... pipetting. Productivity In The Palm Of Your ...
... Ergonomic Design for Unparalleled Comfort Pick one ... the balance. Notice the trigger and ejector positionsright ... because our pipettors are ergonomically designed to help ... of pipetting. Productivity In The Palm Of ...
... The Finnpipette BioControl multichannel has ... the single channel model. The ... seven multichannel and five single ... pipettes have a recharge and ...
Medicine Products: