Navigation Links
Statins linked with lower depression risk in heart patients
Date:2/24/2012

Patients with heart disease who took cholesterol-lowering statins were significantly less likely to develop depression than those who did not, in a study by Mary Whooley, MD, a physician at the San Francisco VA Medical Center and a professor of medicine at the University of California, San Francisco.

The study was published electronically in the Journal of Clinical Psychiatry (February 21, 2012).

Whooley and her research team evaluated 965 heart disease patients for depression, and found that the patients who were on statins were significantly less likely to be clinically depressed than those who were not. They then followed the 776 patients who were not depressed 520 who were using statins and 256 who were not for an additional six years. Of those taking statins, 18.5 percent developed depression, compared with 28 percent of those not on the drugs. Put another way, the patients who took statins were 38 percent less likely to develop depression than patients who did not.

As the study went on, said Whooley, the difference between the two groups became more pronounced, with the patients on statins becoming less likely to develop depression and the patients not on statins becoming more likely to become depressed over time.

"This would suggest that statins may have some kind of long-term protective effect against depression, perhaps by helping to prevent atherosclerosis in the brain, which can contribute to depressive symptoms," Whooley said.

She also noted that statins have positive effects on the endothelium the inner lining of the blood vessels keeping blood vessels less rigid and therefore better able to adapt to the body's changing needs. "The exact mechanism is not known, however, and requires further study," she said.

Whooley cautioned that it is possible that patients who take statins "are just healthier overall than those who don't, and somehow we're not accounting for that in our analysis, even though we adjusted for factors such as smoking, physical activity and cholesterol levels."

If statins are definitively proven to protect against depression, said Whooley, they could be used to reduce the burden of depressive symptoms in patients with heart disease and, by extension, improve cardiovascular outcomes in depressed patients. Whooley has shown in previous studies that heart disease patients with depression are less likely to exercise and take medication, thus increasing their risk for heart attack, stroke, and other cardiovascular events.

Statins are the most commonly-prescribed medication in the world, according to the study authors. "They are relatively safe, and generally well-tolerated," said Whooley.


'/>"/>

Contact: Steve Tokar
steve.tokar@ncire.org
415-221-4810 x5202
University of California - San Francisco
Source:Eurekalert  

Related medicine news :

1. Statins May Benefit Prostate Cancer Patients
2. Alternative to Statins Shows Promise
3. Statins may slow progression of multiple sclerosis, new study finds
4. Statins May Slow Progression of Multiple Sclerosis, New Study Finds
5. Do Statins Lower Male Sex Drive?
6. Statins Wont Lower Colon Cancer Risk
7. Statins decrease risk of clot-related diseases
8. Some statins have unintended effects and warrant closer monitoring, study finds
9. Too Many Stroke Patients Go Without Statins
10. MSU team studies connection between statins, tendon ruptures
11. Statins associated with lower cancer recurrence following prostatectomy
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Statins linked with lower depression risk in heart patients
(Date:10/13/2017)... Worth, TX (PRWEB) , ... October 13, 2017 ... ... financial planning agency serving communities in the greater Dallas, Miami, and Raleigh regions, ... young boy fighting to overcome a rare and deadly chromosome abnormality. , After ...
(Date:10/13/2017)... ... ... While it’s often important to take certain medications during the night, finding ... identified a solution. , She developed a prototype for MOTION LIGHT-UP PILL BOX to ... the need to turn on a light when taking medication during the night, allowing ...
(Date:10/13/2017)... Nevada (PRWEB) , ... October 13, 2017 , ... ... Hemp CBD Oil utilizing Purzorb™ technology. Applying the Purzorb™process to full spectrum CBD oil ... required and providing a CBD form that can be easily incorporated into liquid products, ...
(Date:10/13/2017)... ... , ... Apple Rehab Shelton Lakes , which specializes in the delivery ... as part of a disaster drill on October 3rd. , Apple Rehab participated with ... Manager, as well as the Connecticut Long Term Care Mutual Aid Plan (LTC-MAP). ...
(Date:10/13/2017)... ... October 13, 2017 , ... Ellevate Network, the leading network for ... for action towards gender equality at their inaugural Summit in New York City in ... reached a social audience of over 3 million. To watch the Mobilize Women video, ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... Oct. 2, 2017  AllianceRx Walgreens Prime, the combined ... Walgreens and pharmacy benefit manager Prime Therapeutics LLC (Prime), ... which included the unveiling of new signage at its ... well as at a few other company-owned facilities across ... to patients, some of whom will begin to see ...
(Date:9/28/2017)... , Sept. 28, 2017 Hill-Rom Holdings, Inc. ... earnings conference call and webcast on Friday, November 3, ... (EDT) and ending at approximately 8:30 a.m. (CDT) / ... the company,s 2017 financial performance and guidance for 2018, ... initiatives to enhance operational performance, and long-range financial outlook ...
(Date:9/27/2017)... and NEW YORK , Sept. 27, 2017 /PRNewswire/ ... health and big data solutions, today announced that its MyDario product is ... your local TV listings for when The Dr. Oz Show airs in ... The nine-time ... month. ...
Breaking Medicine Technology: