Navigation Links
Smoking intensity and cancer markers predict seriousness of bladder cancer
Date:1/13/2013

Smoking not only causes bladder cancerit also affects its course, in that people who smoke more have greater likelihood of developing more aggressive and deadly disease. That is one of the conclusions of a new study published early online in CANCER, a peer-reviewed journal of the American Cancer Society. The study also found that a panel of bladder cancer markers can predict which particular cases are at the highest risk for a fatal outcome.

Researchers have known that smoking is one of the most common causes of bladder cancer, but they've wondered whether it also affects how the disease progresses. To investigate, Richard J. Cote, MD, of the University of Miami Miller School of Medicine, and Anirban Mitra, MD, PhD, of the Keck School of Medicine of the University of Southern California, led a team that analyzed bladder tumors and smoking history in 212 multi-ethnic patients recruited through the Los Angeles County Cancer Surveillance Program between 1987 and 1996.

The researchers found that the bladder cancers that developed in individuals who smoked intensely were more likely to be deadly than bladder cancers that developed in those who never smoked, or who smoked less. The study also revealed that changes in particular proteins are often present in bladder cancers that have become deadly. "We have identified a panel of nine molecular markers that can robustly and reproducibly predict bladder cancer prognosis independent of standard clinical criteria and smoking history," said Dr. Mitra. Patients with alterations in six to nine markers had a very poor outcome, raising the hypothesis that these individuals could have benefited from more aggressive treatments.

Because the number of changes in these proteins was directly proportional to patients' health outcomes in a progressive fashion, the findings confirm the theory that an accumulation of changes is more important than individual changes in determining the characteristics o
'/>"/>

Contact: Amy Molnar
sciencenewsroom@wiley.com
Wiley
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Anti-tobacco TV ads help adults stop smoking, study finds
2. Exercise helps smokers to quit smoking, to remain smoke-free and to reduce the risk of death
3. Small neural focus groups predict anti-smoking ad success
4. Some women may be genetically predisposed to smoking-related hot flashes
5. Friends Parents Can Sway Teens Odds for Drinking, Smoking
6. Fewer Young Americans Smoking, Survey Finds
7. Vitamin C improves pulmonary function in newborns of pregnant smoking women
8. Genetic marker may predict smoking quantity in African Americans
9. 5 percent of workers gave up smoking when the anti-tobacco law took effect
10. Vitamin C improves lung function in newborns of pregnant smoking women
11. States Use Only Fraction of Tobacco Revenues to Fight Smoking, Study Finds
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/24/2014)... has recently released a new collection of high quality ... a leading online supplier in the international market. Now, all ... prices, up to 30% off. , “We are happy to ... of our items are offered at low rates. Our affordable ... confidence in our fresh assortment. You will have a safe ...
(Date:11/24/2014)... New York (PRWEB) November 24, 2014 Gersowitz ... today that it has received national Tier recognition in the ... Firms.” Achieving a tiered ranking signals a unique combination of ... are very proud to receive this honor and especially grateful ... made this important honor and ranking possible,” said Jeff S. ...
(Date:11/23/2014)... 2014 For the coming special Friday, ... launched a great promotion for many products, especially the ... get the best choice with amazing discounts, up to ... , It is easy to buy colored wedding ... this selection is also famous for delicate craftsmanship, elegant ...
(Date:11/23/2014)... Nov. 21, 2014 (HealthDay News) -- Close friends have ... peer group does, a new study says. ... peers have an influence on individual alcohol use, but ... broader peer group and the friend group,s influence on ... University,s School of Public Health, said in a university ...
(Date:11/23/2014)... (PRWEB) November 23, 2014 SWAccessControl.com's high ... global market. Recently, the company has announced its new ... special offer on these high quality power suppliers. All ... 30% off. The special offer lasts until Dec. 20, ... many of them have been supporting it for a ...
Breaking Medicine News(10 mins):Health News:SWAccessControl.com Is Happy To Release New Range Of Magnetic Locks 2Health News:U.S. News-Best Lawyers “Best Law Firms” Names Gersowitz Libo & Korek P.C. a 2015 Tier 1 Ranking Firm 2Health News:Beautiful Wedding Dresses Available at Popular B2C Company Tidebuy 2Health News:Close Friends May Be Key to Teens' Drinking 2Health News:Cheap Access Control Power Supplies Online Now at SWAccessControl.com, Special Offer Until Dec. 20, 2014 2
... ... virtual reality device, the GaitAid, can help stroke patients learn to walk better. , ... Haifa, Israel (PRWEB) February 22, 2010 -- There are ... one of the leading causes of adult disability in the U.S. and Europe., , , , ...
... new survey has found that African-Americans are more likely ... lung cancer, as well as being more reluctant to ... according to researchers from Dana-Farber Cancer Institute and their ... the puzzling racial disparities in lung cancer treatment outcomes ...
... outlets for buying booze increases, so does neighborhood violence, ... The more bars, restaurants and other alcohol sales sites ... say researchers who studied crime statistics and alcohol licensing ... found an association between high assault rates and stores ...
... three million children have been born as a result of ... tube baby" in 1978. While the majority of these ... at greater risk of certain kinds of birth defects and ... and type 2 diabetes later in life. Carmen Sapienza, ...
... types of minimally invasive surgery to repair kidney blockages ... found that robot-assisted surgery was faster and resulted in ... in the Canadian Journal of Urology , Ashok ... Baptist Medical Center, compared laparoscopic and robot-assisted surgery for ...
... 20. "Nanotechnology could aid the future of development of the ... the academy of sciences for the developing world, and president ... at a panel session, "Re-emergence of Science, Technology and Education ... AAAS,s annual meeting in San Diego. "The Arab ...
Cached Medicine News:Health News:New Successful Treatment Improves Walking Post Stroke 2Health News:African-Americans' attitudes about lung cancer may hinder prevention 2Health News:More Bars Equals More Assaults, Study Finds 2Health News:Comparison shows robot-assisted option offers advantages for kidney surgery 2Health News:Nanotechnology could help Arab region 2
(Date:11/22/2014)... HILL, N.C. , Nov. 21, 2014 /PRNewswire/ ... healthcare system. Undoubtedly, the growing influence of patients ... spend for marketing interactions. Now, more than ever, ... retain patients for medical products is essential. ... firm, Best Practices, LLC, benchmarked companies spent about ...
(Date:11/21/2014)... , Nov. 21, 2014  The University of Maryland,s ... the ceremonial groundbreaking of the new A. James Clark ... new building will cultivate transformative new engineering and biomedical ... Taking place at 10:00 a.m. on November 21 at ... Branch Parking Lot, adjacent to the Jeong H. Kim ...
(Date:11/21/2014)... 2014  Tandem Diabetes Care ® , Inc. ... company and manufacturer of the t:slim ® ... a non-profit dedicated to improving diabetes therapy management ... increases diabetes data accessibility. This partnership will enable ... under development, to download and access data from ...
Breaking Medicine Technology:New Report Details Importance of Adopting a "Patient Journey" Framework in Marketing 2University of Maryland Breaks Ground for A. James Clark Hall 2University of Maryland Breaks Ground for A. James Clark Hall 3University of Maryland Breaks Ground for A. James Clark Hall 4Tandem Diabetes Care Announces Partnership with Tidepool to Further Expand Access to Diabetes Device Data 2Tandem Diabetes Care Announces Partnership with Tidepool to Further Expand Access to Diabetes Device Data 3
... 12, 2011 If you could learn that you have a ... and 75 percent of that chance could be altered by lifestyle ... of the nation,s leading online direct-to-consumer online lab test and health ... Your Number HealthScore as seen on The Biggest Loser ...
... Oct. 12, 2011 / PRNewswire/ -- ... Hobson as its new president and chief executive ... has been appointed to the Isis Biopolymer board ... has pioneered advancements in polymer chemistry, miniaturization and ...
Cached Medicine Technology:PersonaLabs and BioSignia Join to Offer Targeted Risk Assessment 2Isis Biopolymer Appoints New President and CEO 2
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: