Navigation Links
Smell and eye tests show potential to detect Alzheimer's early
Date:7/13/2014

Biomarkers Lifestyle Study of Aging (AIBL).

Amyloid Detected in the Lens of the Eye Strongly Correlates to Amyloid Levels Detected in the Brain

At AAIC 2014, Paul D. Hartung, M.S, President and CEO of Cognoptix, Inc. and colleagues reported the results of a study of a novel fluorescent ligand eye scanning (FLES) system that detects beta-amyloid in the lens of the eye using a topically-applied ointment that binds to amyloid and a laser scanner.

The researchers studied 20 people with probable Alzheimer's disease, including mild cases, and 20 age-matched healthy volunteers; all participants' Alzheimer's status was masked from the observers. The ointment was applied to the inside of participants' lower eyelids the day before measurement. Laser scanning detected beta-amyloid in the eye by the presence of a specific fluorescent signature. Brain amyloid positron emission tomography (PET) scanning was performed on all participants to estimate amyloid plaque density in the brain.

Using results from the fluorescent imaging, researchers were able to differentiate people with Alzheimer's from healthy controls with high sensitivity (85 percent) and specificity (95 percent). In addition, amyloid levels based on the eye lens test correlated significantly with results obtained through PET brain imaging. No serious adverse events were reported, according to the scientists.

"There is a critical need for a fast, dependable, low-cost and readily available test for the early diagnosis and management of Alzheimer's disease," said Pierre N. Tariot, M.D., Director of the Banner Alzheimer's Institute in Phoenix, and a principal investigator in the study.

"The results of this small Phase 2 feasibility study validate our previously reported results and demonstrate the ability of the FLES system to reproduce the findings of clinical diagnosis of Alzheimer's with high sensitivity and specificity," said Hartung. "This system shows p
'/>"/>

Contact: Alzheimer's Association Media Line
media@alz.org
312-335-4078
Alzheimer's Association
Source:Eurekalert

Page: 1 2 3 4 5 6 7

Related medicine news :

1. Why does bacon smell so good? (video)
2. Claim that raw milk reduces lactose intolerance doesnt pass smell test, study finds
3. Detecting sickness by smell
4. Smells BeGone Air Freshening Aerosol Sprays on Sale at SmellsBeGone.com
5. Mosquitoes smell you better at night, study finds
6. Smells BeGone Launches New Pinterest Page
7. Age-related smelling loss significantly worse in African-Americans
8. Black, Stinky, Smelly Sludge In Pond?
9. Do Latex Mattresses Smell? SleepJunkie.org Clears the Air with Latest Article
10. Foul-smelling gas shows health benefits in reducing joint swelling
11. Smell and taste experts to discuss new discoveries
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/23/2014)... Locks-Magnetic.com, a notable magnetic locks maker, has released a ... are available at low rates up to 30% off. ... new emergency doors. The emergency door adopts fireproof material ... several colors. All of the products are top-quality guaranteed. ... not as easy as many people think. As ...
(Date:11/23/2014)... (PRWEB) November 23, 2014 More than ... month in a federal litigation involving Byetta lawsuits ( ... medications, Bernstein Liebhard LLP reports. , A Case ... over a class of Type 2 diabetes medications referred ... the U.S. District Court, Southern District of California, where ...
(Date:11/23/2014)... Falls Church, VA (PRWEB) November 23, 2014 ... and TV Have in Common, **FDAnews On-Demand Webinar**, Dec. ... http://www.fdanews.com/TheFDAisWatchingOnDemand , The FDA’s focus on promotional ... ads. , Now they're looking at websites, ... , Mark the calendar for Thursday, Dec. 11, for ...
(Date:11/23/2014)... 23, 2014 Today Zane Benefits, ... small businesses, announced their new on demand webinar ... Employer-Provided Health Insurance. , According to ... financial risk facing most American families. It is ... and large, when it comes to recruiting and ...
(Date:11/22/2014)... PrettyTailor , an outstanding dress company, ... promotion. Customers can buy new dresses at its online ... its website. , As a matter of fact, PrettyTailor ... mainly provides four types of wedding outfits, including bridesmaid ... dresses. It also provides a variety of occasion dresses, ...
Breaking Medicine News(10 mins):Health News:California Federal Court Overseeing Byetta Lawsuits, Other Incretin Mimetic Claims Adds New Cases in November, Bernstein Liebhard LLP Reports 2Health News:California Federal Court Overseeing Byetta Lawsuits, Other Incretin Mimetic Claims Adds New Cases in November, Bernstein Liebhard LLP Reports 3Health News:California Federal Court Overseeing Byetta Lawsuits, Other Incretin Mimetic Claims Adds New Cases in November, Bernstein Liebhard LLP Reports 4Health News:FDAnews Announces The FDA is Watching: What Twitter, Tradeshows and TV Have in Common, On-Demand Webinar, Dec. 11, 2014 2Health News:FDAnews Announces The FDA is Watching: What Twitter, Tradeshows and TV Have in Common, On-Demand Webinar, Dec. 11, 2014 3Health News:FDAnews Announces The FDA is Watching: What Twitter, Tradeshows and TV Have in Common, On-Demand Webinar, Dec. 11, 2014 4Health News:FDAnews Announces The FDA is Watching: What Twitter, Tradeshows and TV Have in Common, On-Demand Webinar, Dec. 11, 2014 5Health News:Zane Benefits, Inc. Announces New Webinar on The End of Employer-Provided Health Insurance Now Available On-Demand! 2Health News:Customers Are Welcome to Shop at PrettyTailor.com 2
... standard part of testicular cancer care isnt used in ... condition, researchers at the University of Michigan Comprehensive Cancer ... one indicator of the presence of cancer cells, are ... with testis cancer, including diagnosis, prognostication and surveillance for ...
... 26-Week Study, WILMINGTON, Del., March 17 ... combination asthma therapy,SYMBICORT(R) (budesonide/formoterol fumarate dihydrate), in treating,persistent ... The study examined the,safety of SYMBICORT in children ... children previously treated with inhaled corticosteroid,either alone or ...
... Reduces Surgery Time, AUDUBON, Pa., March ... held spinal implant manufacturer in the world, ... Spacer System. The,new system significantly reduces the ... by offering an unprecedented array of,interoperative options. ...
... Kim Watson to Expand Global Partnerships for Clean Pesticide and Animal ... ... March 17 TyraTech (AIM:,TYR), a pioneer of safer, effective and ... markets, announced today,the appointment of Kim Watson as Senior Director Business ...
... March 17 Conseco, Inc. (NYSE:,CNO) today announced that ... to nominate two of its representatives to Conseco,s board ... strategic,alternatives and has engaged the investment banking firm of ... Prieur said, "We share with Steel Partners, as well ...
... SPRINGVILLE, Calif., March 17 Tropical Traditions,announced today that ... line. It is believed to be the first product ... made from the water inside of coconuts is a,cottage ... Water from,the inside of coconuts is highly valued due ...
Cached Medicine News:Health News:Testicular cancer gauge often not used 2Health News:Study Analyzed Long-Term SYMBICORT(R) Use in Children With Persistent Asthma 2Health News:Study Analyzed Long-Term SYMBICORT(R) Use in Children With Persistent Asthma 3Health News:Study Analyzed Long-Term SYMBICORT(R) Use in Children With Persistent Asthma 4Health News:Globus Medical Launches NIKO(TM) Corpectomy Spacer System 2Health News:TyraTech Adds New Sr. Director Business Development 2Health News:TyraTech Adds New Sr. Director Business Development 3Health News:Tropical Traditions Announces New Organic Raw Coconut Water Vinegar 2
(Date:11/21/2014)... , Nov. 20, 2014  The acceptance of ... 2014 AAGL Global Congress demonstrates continued interest in ... to provide bowel control. One of the abstracts, presented ... and Division Chief of Urogynecology and Reconstructive Pelvic ... an Award for Best Written Abstract on Urogynecology/Pelvic ...
(Date:11/21/2014)... , Nov. 20, 2014   Coqui RadioPharmaceuticals Corp. ... first U.S. commercial producer of Molybdenum-99 (Mo-99), is proud ... INVAP to design its Medical Isotope Production ... Mo-99 is the parent isotope of Technetium-99, which is ... In 2012, Congress passed legislation making it a national ...
(Date:11/21/2014)... , Nov. 21, 2014  Lexicon Pharmaceuticals, Inc. (Nasdaq: ... its previously announced underwritten public offering of $50,000,000 of ... shelf registration statement. The offering will consist of 49,751,244 ... of $1.005 per share.  Lexicon has also granted the ... additional shares of common stock.  All of the shares ...
Breaking Medicine Technology:LIFE Study Prominently Featured at Minimally Invasive Gynecology Conference 2LIFE Study Prominently Featured at Minimally Invasive Gynecology Conference 3Coqui RadioPharmaceuticals Inks Deal With INVAP 2Lexicon Announces Pricing Of Common Stock Offering 2Lexicon Announces Pricing Of Common Stock Offering 3
... FDA approvals for prostate cancer treatment medications from ... of men with advanced prostate cancer were prolonged ... & Johnson. The drug, which could reach the market in ... the potential to change clinical practice by providing a new ...
... The Food and Drug Administration (FDA) is warning there ... thigh bone fracture in people who take drugs known ... http://photos.prnewswire.com/prnh/20090824/FDALOGO ) (Logo: http://www.newscom.com/cgi-bin/prnh/20090824/FDALOGO ) ... type of fracture has been predominantly reported in patients ...
Cached Medicine Technology:Robotic Prostatectomy Expert Dr. David Samadi, MD Discusses Prostate Cancer Treatment Drug Abiraterone 2
Colloidal Gold Sol, 40 nm - 12 - 15, 1 ml, Gold Sol Nanoparticles - not boiled, not centrifuged...
... magnification all glass (1.5x) Gonio lens will ... ease., The 4 mirror lens is the ... dynamic gonioscopy and features : , ... appreciate details previously unattainable with Gonio lenses., ...
Colloidal Gold Sol, 20 nm - 50 OD, 1 ml, Gold Sol Nanoparticles - not boiled, not centrifuged...
... The PalmScan P2000 Pachymeter [i.e., PalmScan ... portable,battery operated biometer, which incorporates A-mode ... used to accurately measure the corneal ... human eyes. PalmScan P2000 includes two ...
Medicine Products: