Navigation Links
Scientists slow brain tumor growth in mice
Date:5/13/2014

Much like using dimmer switches to brighten or darken rooms, biochemists have identified a protein that can be used to slow down or speed up the growth of brain tumors in mice.

Brain and other nervous system cancers are expected to claim 14,320 lives in the United States this year.

The results of the preclinical study led by Eric J. Wagner, Ph.D., and Ann-Bin Shyu, Ph.D., of The University of Texas Health Science Center at Houston (UTHealth) and Wei Li, Ph.D., of Baylor College of Medicine appear in the Advance Online Publication of the journal Nature.

"Our work could lead to the development of a novel therapeutic target that might slow down tumor progression," said Wagner, assistant professor in the Department of Biochemistry and Molecular Biology at the UTHealth Medical School.

Shyu, professor and holder of the Jesse H. Jones Chair in Molecular Biology at the UTHealth Medical School, added, "This link to brain tumors wasn't previously known."

"Its role in brain tumor progression was first found through big data computational analysis, then followed by animal-based testing. This is an unusual model for biomedical research, but is certainly more powerful, and may lead to the discovery of more drug targets," said Li, an associate professor in the Dan L. Duncan Cancer Center and Department of Molecular and Cellular Biology at Baylor.

Wagner, Shyu, Li and their colleagues discovered a way to slow tumor growth in a mouse model of brain cancer by altering the process by which genes are converted into proteins.

Appropriately called messenger RNA for short, these molecules take the information inside genes and use it to make body tissues. While it was known that the messenger RNA molecules associated with the cancerous cells were shorter than those with healthy cells, the mechanism by which this occurred was not understood.

The research team discovered that a protein called CFIm25 is cr
'/>"/>

Contact: Robert Cahill
Robert.Cahill@uth.tmc.edu
713-500-3030
University of Texas Health Science Center at Houston
Source:Eurekalert  

Page: 1 2 3

Related medicine news :

1. UBC scientists find new way to mobilize immune system against viruses
2. Dartmouth scientists identify genetic blueprint for cancerous tumors of the appendix
3. Scientists decode epigenetic mechanisms distinguishing stem cell function and blood cancer
4. Scientists identify new protein in the neurological disorder dystonia
5. Scientists awarded grant to develop diagnostics for cancer, rheumatoid arthritis, colitis
6. Norwegian neuroscientists elected to National Academy of Sciences
7. NIH scientists establish monkey model of hantavirus disease
8. Stanford scientists create circuit board modeled on the human brain
9. A civil war inside our cells: Scientists show how our bodies fight off jumping genes
10. Scientists find way to target cells resistant to chemo
11. Scientists identify cancer specific cell for potential treatment of gastric cancer
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Scientists slow brain tumor growth in mice
(Date:3/27/2015)... 2015 Ticket Down is a reputable source ... in Omaha, Nebraska on Friday, May 8th and Saturday, ... dates will be added in Omaha as Garth has done ... The Garth Brooks World Tour is continuing its run throughout ... Garth Brooks and Trisha Yearwood will bring their act to ...
(Date:3/27/2015)... (PRWEB) March 27, 2015 The report ... an essential source of information on and analysis of ... The population of the US in 2013 amounted to ... Rate (CAGR) of 0.8% from 2008. The country’s increasingly ... chronic diseases will help to boost the growth of ...
(Date:3/27/2015)... (PRWEB) March 27, 2015 California’s ongoing ... blizzards in Boston and the United States Northeast, are ... Earth warming global atmosphere is creating changes in the ... historical climatologist and former NASA researcher, speaking on the ... result is not only a warmer and dryer global ...
(Date:3/27/2015)... MN (PRWEB) March 27, 2015 ... Minnesotans for Healthy Kids Coalition Lobby Day to ... Statewide Health Improvement Program (SHIP). Everlast Climbing ... 2015 PE Bill SF343/HF498 which would strengthen physical ... annual student assessments and other measures to strengthen ...
(Date:3/27/2015)... Irvine, CA (PRWEB) March 27, 2015 ... nation’s leading providers of business support services to dental ... opening of an affiliated Castle Dental office ... Lake Blvd. Hendersonville, TN 37075, this new Castle Dental ... they can receive the latest in comprehensive, quality dental ...
Breaking Medicine News(10 mins):Health News:Cheap Garth Brooks Tickets for CenturyLink Center in Omaha: Ticket Down Slashes Garth Brooks Concert Tickets in Omaha, NE at the CenturyLink Center 2Health News:Cheap Garth Brooks Tickets for CenturyLink Center in Omaha: Ticket Down Slashes Garth Brooks Concert Tickets in Omaha, NE at the CenturyLink Center 3Health News:US Pharmaceutical Market worth $548.4 billion by 2020 Says a New Report Available at RnRMarketResearch.com 2Health News:US Pharmaceutical Market worth $548.4 billion by 2020 Says a New Report Available at RnRMarketResearch.com 3Health News:US Pharmaceutical Market worth $548.4 billion by 2020 Says a New Report Available at RnRMarketResearch.com 4Health News:California Drought, Boston Blizzards Both Attributed to Global Climate Change Reports Climatologist to Fresh Water Advocate 2Health News:California Drought, Boston Blizzards Both Attributed to Global Climate Change Reports Climatologist to Fresh Water Advocate 3Health News:Everlast Climbing Advocates to Strengthen Physical Education in Minnesota Schools 2Health News:Castle Dental® Opens Its First Dental Office in Hendersonville, TN 2Health News:Castle Dental® Opens Its First Dental Office in Hendersonville, TN 3
... Gardner HealthDay Reporter , TUESDAY, May 3 (HealthDay ... to deployment or who,ve been injured during combat are more ... home. The PTSD tends to be worse with more ... of the Archives of General Psychiatry . The ...
... drug selectively kills the cancerous cells that cause chronic ... at the Ohio State University Comprehensive Cancer Center ... Research Institute (OSUCCC James). The study shows that ... lymphocytes that cause chronic lymphocytic leukemia (CLL). , ...
... or emergency medical technician providing first aid with a ... bleeding, fights bacteria (and other sources of infection), stimulates ... it is quickly absorbed by surrounding tissue may ... Or, imagine diabetics with hard-to-heal wounds finding a source ...
... develop a pioneering tool to help tailor the treatment of ... a new EU project. The 5-year AirPROM* project, which ... and physical models of the whole airways system, to help ... treatments. The news comes on World Asthma Day ...
... -- Few Americans bother to read the labels on over-the-counter ... drugs, ingredients, a new study says. This lack of ... a leading cause of acute liver failure in the United ... Acetaminophen, the active ingredient in Tylenol, is in more ...
... FOR DETERMINING SOURCE OF ACUTE SHORTNESS OF BREATH ... replace standard chest x-ray as the first choice of ... source of acute dyspnea is needed. Italian researchers studied ... strong agreement between the results of chest ultrasonography and ...
Cached Medicine News:Health News:Military Personnel With Mental Woes Before Deployment at Higher PTSD Risk 2Health News:Agent selectively targets malignant B cells in chronic leukemia, study shows 2Health News:New cotton candy-like glass fibers appear to speed healing in venous stasis wound trial 2Health News:New cotton candy-like glass fibers appear to speed healing in venous stasis wound trial 3Health News:New cotton candy-like glass fibers appear to speed healing in venous stasis wound trial 4Health News:Virtual lung models set to personalize asthma and COPD treatment 2Health News:Many Consumers Don't Know What's in Over-the-Counter Painkillers: Study 2Health News:Chest journal news briefs, May 2011 issue 2
(Date:3/26/2015)... 2015 Over-the-counter healthcare costs can be ... a new survey of store brand over-the-counter products ... cold to diabetes, can offer significant savings for ... the Private Label Manufacturers Association, assembled a market ... those essential for treatment of pre-diabetes and diabetes. ...
(Date:3/26/2015)... , March 26, 2015 A new ... that comparative effectiveness research (CER) will yield improvements ... yet seeing the impact of CER in the ... annual survey of stakeholders shows that they view ... impact on health care and decision-making in the ...
(Date:3/26/2015)... -- Desert Valley Medical Center, named a Top 100 Hospitals® ... first U.S. hospital to deploy the wireless Leaf Patient ... prevent hospital acquired pressure ulcers. Desert Valley, ... a community hospital serving some higher risk populations, including ... in the hospital,s emergency department enables the clinical staff ...
Breaking Medicine Technology:Consumers can keep over-the-counter medicine affordable by using store brands 2NPC Highlights Stakeholder Views on Comparative Effectiveness Research and the Environment for Health Care Decision-Making 2NPC Highlights Stakeholder Views on Comparative Effectiveness Research and the Environment for Health Care Decision-Making 3NPC Highlights Stakeholder Views on Comparative Effectiveness Research and the Environment for Health Care Decision-Making 4Desert Valley Medical Center First to Use Leaf Healthcare Patient Wearable Technology in its ED as Part of Hospital-wide Deployment 2Desert Valley Medical Center First to Use Leaf Healthcare Patient Wearable Technology in its ED as Part of Hospital-wide Deployment 3
... Minocycline Showed Substantial,Reduction of Disease Activity in ... Treatment With Antibiotic Further Reduced Brain,Lesions and ... May 4, 2007 - New data from ... of Copaxone,(glatiramer acetate injection) along with the ...
... 2007 - Lux Biosciences,Inc., a privately held biotechnology ... today that the company's,next-generation calcineurin inhibitor, LX211, is ... Research in Vision and,Ophthalmology (ARVO) annual meeting, being ... an oral presentation being given on May 5 ...
Cached Medicine Technology:Treatment with Copaxone Plus Minocycline Showed Substantial,Reduction of Disease Activity in Patients with Active,Relapsing-Remitting Multiple Sclerosis 2Treatment with Copaxone Plus Minocycline Showed Substantial,Reduction of Disease Activity in Patients with Active,Relapsing-Remitting Multiple Sclerosis 3Treatment with Copaxone Plus Minocycline Showed Substantial,Reduction of Disease Activity in Patients with Active,Relapsing-Remitting Multiple Sclerosis 4Treatment with Copaxone Plus Minocycline Showed Substantial,Reduction of Disease Activity in Patients with Active,Relapsing-Remitting Multiple Sclerosis 5Treatment with Copaxone Plus Minocycline Showed Substantial,Reduction of Disease Activity in Patients with Active,Relapsing-Remitting Multiple Sclerosis 6Treatment with Copaxone Plus Minocycline Showed Substantial,Reduction of Disease Activity in Patients with Active,Relapsing-Remitting Multiple Sclerosis 7Treatment with Copaxone Plus Minocycline Showed Substantial,Reduction of Disease Activity in Patients with Active,Relapsing-Remitting Multiple Sclerosis 8Treatment with Copaxone Plus Minocycline Showed Substantial,Reduction of Disease Activity in Patients with Active,Relapsing-Remitting Multiple Sclerosis 9Treatment with Copaxone Plus Minocycline Showed Substantial,Reduction of Disease Activity in Patients with Active,Relapsing-Remitting Multiple Sclerosis 10Treatment with Copaxone Plus Minocycline Showed Substantial,Reduction of Disease Activity in Patients with Active,Relapsing-Remitting Multiple Sclerosis 11Treatment with Copaxone Plus Minocycline Showed Substantial,Reduction of Disease Activity in Patients with Active,Relapsing-Remitting Multiple Sclerosis 12Lux Biosciences' Investigational Therapy for Uveitis, LX211, is,Subject of Two Presentations at Key Ophthalmology Meeting, ARVO,2007 2Lux Biosciences' Investigational Therapy for Uveitis, LX211, is,Subject of Two Presentations at Key Ophthalmology Meeting, ARVO,2007 3Lux Biosciences' Investigational Therapy for Uveitis, LX211, is,Subject of Two Presentations at Key Ophthalmology Meeting, ARVO,2007 4
Provides compression, support, immobilization for the knee in addition to cold / hot therapy...
Provides extended cold therapy to the shoulder area for acute, chronic, or post-surgical applications. The DuraKold products can help reduce pain, edema, and speed recovery....
Provides continuous cold therapy to the knee area for acute, chronic, or post-surgical applications. Cryotherapy can reduce pain, swelling and facilitate faster rehabilitation....
... designed in 1988 as an attachment to the ... greatly restricts rotation of the cervical spine. , ... be removed while allowing the Collar to remain ... conjunction with the Philadelphia Stabilizer attachment., ,Every ...
Medicine Products: