Navigation Links
Scientists move towards stem cell therapy trials to mend shattered bones
Date:2/18/2008

The UK Stem Cell Foundation, the Medical Research Council and Scottish Enterprise, in partnership with the Chief Scientists Office, are funding a 1.4 million project to further the research at the University of Edinburgh with a view to setting up a clinical trial within two years.

The initiative could have a major impact on treating conditions such as osteoarthritis as well as treating trauma victims whose bones have been shattered beyond repair.

It involves using a bioactive scaffold made to protect the stem cells and simulate their growth into bone or cartilage once they are placed in the affected area. The scaffold consists of a fairly rigid mesh structure, coated or impregnated with a drug that affects the patients cells.

Dr Brendon Noble, of the University of Edinburghs MRC Centre for Regenerative Medicine, said: This is a novel approach in terms of treating damaged bones and cartilage. The aim is to translate the knowledge we have gained from bone biology studies into tangible treatments for patients.

Researchers will also work with clinicians, headed by Hamish Simpson, professor of orthopaedics and trauma at the University of Edinburgh, with a view to eventually translating their findings into treatments for patients.

As well as using cells derived from bone marrow, the scientists will work in collaboration with the Scottish National Blood Transfusion Service to culture bone forming cells derived from blood.

The advantage of these blood-sourced cells is that they can be extracted without the need for surgery. The use of a patients own stem cells means that they are also unlikely to be rejected.

Dr Anna Krassowska, research manager for the UK Stem Cell Foundation said: In the UK hip fractures kill 14,000 elderly people every year - more than many cancers. The worldwide market for orthopaedic devices alone represents some $17 billion. This research has the potential not only to impact on a significant number of people's lives but to open up one of the largest stem cell markets in the industry.

For nearly a decade, scientists have known broadly the right chemical conditions required to encourage undifferentiated stem cells taken from a patient's bone marrow to change into bone and cartilage cells in the laboratory. However, the use of the bioactive scaffold being developed at the University of Edinburgh aims to enable these cells to grow within the human body. The initial clinical trial, resulting from the laboratory work is likely to involve around 30 patients.


'/>"/>

Contact: Tara Womersley
tara.womersley@ed.ac.uk
01-316-509-836
University of Edinburgh
Source:Eurekalert

Related medicine news :

1. New prion protein discovered by Canadian scientists may offer insight into mad cow disease
2. Scientists Probe Sepsis Deadly Secrets
3. Scientists puzzled by severe allergic reaction to cancer drug in the middle Southern US
4. Scientists Develop Natural Protection for Stored Foods
5. Scientists detect presence of marburg virus in african fruit bats
6. Scientists Spot Brains Free Will Center
7. Scientists ID Likely Culprit in Popcorn Lung
8. Scientists explain how insulin secreting cells maintain their glucose sensitivity
9. Scripps Research scientists shed new light on how antibodies fight HIV
10. Scientists, physicians present latest findings in personalized cancer treatment and prevention
11. Scientists demonstate link between genetic variant and effectiveness of smoking cessation meds
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/24/2017)... ... February 24, 2017 , ... Yisrayl Hawkins, Pastor and ... Bible Prophecy concerning this present generation. Yisrayl makes an astounding statement when he ... He explains that the Bible details the current times so plainly that anyone ...
(Date:2/24/2017)... ... 24, 2017 , ... The Radiology Business Management Association will select ... the annual Building Better Radiology Marketing Programs conference, held this year from ... Texas. Nine awards are given out in five categories. They are:, ...
(Date:2/24/2017)... , ... February 24, 2017 , ... ... Charlevoix, once again hosted their Military Wedding Giveaway, with the winning couple announced ... Castle Farms with services generously donated from local vendors: A Matter of Taste, ...
(Date:2/23/2017)... ... 23, 2017 , ... The 89th Academy Awards will be celebrated this weekend, ... Policy Center Bunkum Award. We invite you to enjoy our 11th annual tongue-in-cheek “salute” ... is the Center for American Progress (CAP), for its report, Lessons From State Performance ...
(Date:2/23/2017)... ... 23, 2017 , ... The American Cleft Palate-Craniofacial Association (ACPA) is pleased to ... is a longtime supporter of the event. , "We are pleased that KLS Martin ... Bob Havlik, 2017 ACPA President. "KLS Martin has a long track record of support ...
Breaking Medicine News(10 mins):
(Date:2/24/2017)... , Feb 24, 2017 Research and ... Price Analysis and Strategies - 2016" report to their offering. ... The latest ... drug pricing data and benchmarks in the global Urinary Incontinence market. ... What are the key drugs marketed for Urinary Incontinence and ...
(Date:2/23/2017)... -- LG Innotek hat heute die weltweit erste 70 mw ... 1,5-fache des 45-mW-Moduls der Konkurrenz. UV-C LED ... 280 nm und eignet sich damit für Sterilisationsaufgaben. Es verhindert ... Das Produkt von LG Innotek erzeugt UV-Strahlung im Bereich ... ...
(Date:2/23/2017)... and Markets has announced the addition of the "Menopause Drugs Price ... ... Analysis and Strategies - 2016, provides drug pricing data and benchmarks in ... What are the key drugs marketed for Menopause ... market? What are the unit prices and annual treatment ...
Breaking Medicine Technology: