Navigation Links
Scientists move towards stem cell therapy trials to mend shattered bones
Date:2/18/2008

The UK Stem Cell Foundation, the Medical Research Council and Scottish Enterprise, in partnership with the Chief Scientists Office, are funding a 1.4 million project to further the research at the University of Edinburgh with a view to setting up a clinical trial within two years.

The initiative could have a major impact on treating conditions such as osteoarthritis as well as treating trauma victims whose bones have been shattered beyond repair.

It involves using a bioactive scaffold made to protect the stem cells and simulate their growth into bone or cartilage once they are placed in the affected area. The scaffold consists of a fairly rigid mesh structure, coated or impregnated with a drug that affects the patients cells.

Dr Brendon Noble, of the University of Edinburghs MRC Centre for Regenerative Medicine, said: This is a novel approach in terms of treating damaged bones and cartilage. The aim is to translate the knowledge we have gained from bone biology studies into tangible treatments for patients.

Researchers will also work with clinicians, headed by Hamish Simpson, professor of orthopaedics and trauma at the University of Edinburgh, with a view to eventually translating their findings into treatments for patients.

As well as using cells derived from bone marrow, the scientists will work in collaboration with the Scottish National Blood Transfusion Service to culture bone forming cells derived from blood.

The advantage of these blood-sourced cells is that they can be extracted without the need for surgery. The use of a patients own stem cells means that they are also unlikely to be rejected.

Dr Anna Krassowska, research manager for the UK Stem Cell Foundation said: In the UK hip fractures kill 14,000 elderly people every year - more than many cancers. The worldwide market for orthopaedic devices alone represents some $17 billion. This research has the potential not only to impact on
'/>"/>

Contact: Tara Womersley
tara.womersley@ed.ac.uk
01-316-509-836
University of Edinburgh
Source:Eurekalert

Page: 1 2

Related medicine news :

1. New prion protein discovered by Canadian scientists may offer insight into mad cow disease
2. Scientists Probe Sepsis Deadly Secrets
3. Scientists puzzled by severe allergic reaction to cancer drug in the middle Southern US
4. Scientists Develop Natural Protection for Stored Foods
5. Scientists detect presence of marburg virus in african fruit bats
6. Scientists Spot Brains Free Will Center
7. Scientists ID Likely Culprit in Popcorn Lung
8. Scientists explain how insulin secreting cells maintain their glucose sensitivity
9. Scripps Research scientists shed new light on how antibodies fight HIV
10. Scientists, physicians present latest findings in personalized cancer treatment and prevention
11. Scientists demonstate link between genetic variant and effectiveness of smoking cessation meds
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2014)... targets that could be used to provide relief ... London made the discovery when researching how pain ... body. , Dr Marzia Malcangio said: "We have ... and our findings could help chemotherapy patients who ... side effect of some chemotherapy drugs (such as ...
(Date:4/17/2014)... Two recent papers by a University of ... help scientists develop treatments or vaccines for Dengue ... and other disease-causing flaviviruses. , Jeffrey S. Kieft, ... at the School of Medicine and an early ... and colleagues recently published articles in the scholarly ...
(Date:4/17/2014)... Doctors who treat patients with a severe ... face an agonizing treatment decision. , The drug ... help relieve shortness of breath. But some patients ... cause potentially fatal complications following transplantation. , "It,s ... medical director of Loyola University Medical Center,s LAM ...
(Date:4/17/2014)... School of Medicine (BUSM) have discovered that the ... experimental model. The findings, reported in the ... may lead to more effective treatments for alcoholism. ... the leading causes of illness and death in ... by limiting the productivity of workers and necessitating ...
(Date:4/17/2014)... scientists and their partners have found that their proprietary ... transmission of multiple sexually transmitted infections (STIs) in both ... virus 2 (HSV-2), and human papillomavirus (HPV). The USAID-funded ... is effective against multiple strains of HIV, and has ... three viruses of at least eight hours prior to ...
Breaking Medicine News(10 mins):Health News:New pain relief targets discovered 2Health News:CU researchers discover target for treating dengue fever 2Health News:Patients with rare lung disease face agonizing treatment dilemma 2Health News:Patients with rare lung disease face agonizing treatment dilemma 3Health News:BUSM researchers find anti-seizure drug may reduce alcohol consumption 2Health News:Animal study provides first evidence that gel can prevent multiple virus transmission in vagina/rectum 2
... Ill. , Feb. 10  Bright Hope, a Christian ... a $1 a day has been serving the ... in their partner network, they are strategically positioned to carry out ... OCHA reports estimate the number of Internally Displaced People (IDP,s) is ...
... TORRANCE, Calif. , Feb. 10 Henry Loubet ... join the Editorial Board of Payers & Providers , the ... California .  Keenan is the largest privately held insurance brokerage ... Providers delivers in-depth industry coverage, breaking news and a lively ...
... what factors may influence who contracts tuberculosis (TB)/HIV co-infection in ... of the disease, with the majority of cases now coming ... "HIV and Tuberculosis Co-infection Among Hispanics in Southern California: An ... the American Journal of Public Health. ...
... help explain osteoporosis among those with the eating disorder , ... disorder anorexia nervosa have excess levels of fat in their ... affects mainly young women, leads to extremely low body weight ... counterintuitive that an emaciated young woman with almost no subcutaneous ...
... , ... provides users easy access to validated asset documents and,drawings. , ... Orlando, FL (PRWEB) February 10, 2010 -- McLaren Software ... showcasing McLaren Services for Outlook at the ARC Advisory World Industry Forum in Orlando, Florida., ...
... , , Go Red For Women ... highlights , - Minority women,s awareness remains behind that of white ... heart attack warning signs or said they would dial 9-1-1 if ... women surveyed listed therapies to prevent cardiovascular disease that are not ...
Cached Medicine News:Health News:Haiti Relief: New Plans, New Hope 2Health News:Haiti Relief: New Plans, New Hope 3Health News:Keenan Chief Strategy Officer Selected to Join Editorial Board of Payers & Providers 2Health News:Keenan Chief Strategy Officer Selected to Join Editorial Board of Payers & Providers 3Health News:Burden of HIV/TB infections increasingly falling on Hispanic community 2Health News:With Anorexia, Body May Hoard Fat in Bones 2Health News:McLaren Software Extends the Reach of Asset Document Management Processes 2Health News:American Heart Association Rapid Access Journal Report: Study Finds Racial Gaps Continue in Heart Disease Awareness, Low Knowledge of Heart Attack Warning Signs Among Women 2Health News:American Heart Association Rapid Access Journal Report: Study Finds Racial Gaps Continue in Heart Disease Awareness, Low Knowledge of Heart Attack Warning Signs Among Women 3Health News:American Heart Association Rapid Access Journal Report: Study Finds Racial Gaps Continue in Heart Disease Awareness, Low Knowledge of Heart Attack Warning Signs Among Women 4
(Date:1/15/2014)... , Jan. 15, 2014 Massachusetts General ... AMGN ) announced today that they ... and validate new therapeutic targets and develop novel ... disorder that affects millions worldwide. The MGH-Broad-Amgen collaboration ...
(Date:1/15/2014)... , Jan. 15, 2014  Manufacturers, suppliers and ... be able to protect their most important business ... http://photos.prnewswire.com/prnh/20130716/CL46586LOGO ) Because of the ... steadfastly remains one of the most litigious industry ...
(Date:1/15/2014)...  Echo Therapeutics, Inc. (Nasdaq: ECTE ) ("Echo"), ... as a non-invasive, wireless continuous glucose monitoring system, today ... and Interim CEO of Echo Therapeutics, will present at ... Mr. Doman will make a corporate ...
Breaking Medicine Technology:Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 2Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 3Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 4Intellectual Property Insurance for Medical-related Products and Services 2Echo Therapeutics to Present at the Noble Financial Capital Markets' Tenth Annual Equity Conference 2Echo Therapeutics to Present at the Noble Financial Capital Markets' Tenth Annual Equity Conference 3
... 16 BioVex Inc, a biotechnology,company developing clinical ... that the abstract describing the interim results,from its ... advanced metastatic,melanoma is now available at the American ... http://www.asco.org . A summary of the abstract,which describes ...
... Nektar,s Technology Enables First-Ever PEGylation of a Small Molecule with ... Demonstrated Therapeutic ... NKTR ) announced initial results today from a Phase ... activity in patients with refractory solid tumors. The study,also demonstrates ...
Cached Medicine Technology:BioVex to Report Phase II Clinical Trial Results of OncoVEX GM-CSF in Metastatic Melanoma at the 2008 American Society of Clinical Oncology Meeting 2BioVex to Report Phase II Clinical Trial Results of OncoVEX GM-CSF in Metastatic Melanoma at the 2008 American Society of Clinical Oncology Meeting 3Significant Anti-Tumor Activity of NKTR-102 in Patients With Refractory Solid Tumors; Interim Data Published in ASCO 2008 Proceedings 2Significant Anti-Tumor Activity of NKTR-102 in Patients With Refractory Solid Tumors; Interim Data Published in ASCO 2008 Proceedings 3Significant Anti-Tumor Activity of NKTR-102 in Patients With Refractory Solid Tumors; Interim Data Published in ASCO 2008 Proceedings 4Significant Anti-Tumor Activity of NKTR-102 in Patients With Refractory Solid Tumors; Interim Data Published in ASCO 2008 Proceedings 5
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: