Navigation Links
Scientists Find Clue to Aging Reversal in Mice
Date:1/31/2013

THURSDAY, Jan. 31 (HealthDay News) -- A discovery about the aging process in mice might one day help efforts to develop treatments for age-related diseases in humans, researchers report.

The biologists say they turned back the "molecular clock" in old mice by placing a "longevity" gene into their blood stem cells.

The gene, called SIRT3, belongs to a class of proteins called sirtuins, which help aged blood stem cells handle stress. Placing SIRT3 into the blood stem cells of old mice increased the formation of new blood cells, the investigators found. This, according to the researchers, is evidence of a reversal in the age-related decline in the old stem cells' function.

"We already know that sirtuins regulate aging, but our study is really the first one demonstrating that sirtuins can reverse aging-associated degeneration, and I think that's very exciting," study principal investigator Danica Chen, an assistant professor of nutritional science and toxicology at the University of California, Berkeley, said in a university news release.

The finding "opens the door to potential treatments for age-related degenerative diseases," Chen said.

The study was published online Jan. 31 in the journal Cell Reports.

Research over the past 10 to 20 years has led to breakthroughs in the understanding of aging, Chen said. Whereas aging had been previously looked upon as a random and uncontrolled process, it is now believed to be highly regulated and possibly even open to manipulation, she noted.

"Studies have already shown that even a single gene mutation can lead to lifespan extension," Chen said. "The question is whether we can understand the process well enough so that we can actually develop a molecular fountain of youth. Can we actually reverse aging? This is something we're hoping to understand and accomplish."

Experts note, however, that results from animal research are not always able to be replicated in humans.

More information

The U.S. National Institute on Aging offers healthy aging tips.

-- Robert Preidt

SOURCE: University of California, Berkeley, news release, Jan. 31, 2013


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Leading researchers warn of brain drain as scientists struggle to find funding
2. UNC scientists unveil a superbugs secret to antibiotic resistance
3. Scientists learn more about how inhibitory brain cells get excited
4. New target to stop cancers spread discovered by Georgia State scientists
5. Scientists create 1-step gene test for mitochondrial diseases
6. Scientists Complete 1st Map of Emotional Intelligence in the Brain
7. Singapore scientists led by A*STARs GIS identify 4 mechanisms that contribute to gastric cancers
8. National Cancer Centre Singapore scientists discover p53 mutation hinders cancer treatment response
9. HIV-Like Virus Arose in Primates Millions of Years Ago, Scientists Say
10. Scientists Link More Genes to Common Brain Tumor
11. Temple scientists find cancer-causing virus in the brain, potential connection to epilepsy
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Scientists Find Clue to Aging Reversal in Mice
(Date:1/18/2017)... , ... January 18, 2017 , ... ... Fischell Department of Bioengineering are collaborating on a research project focused on multiple ... the project seeks to use nanotechnology to control the disease without compromising normal ...
(Date:1/18/2017)... ... 2017 , ... A Palm Beach doctor plans to run the 2017 London ... provides free surgery to poor children suffering from cleft lip and cleft palate. , ... to support the efforts of the American Heart Association and the Leukemia and Lymphoma ...
(Date:1/18/2017)... ... January 18, 2017 , ... At Hallmark Nameplate, their commitment to quality ... achieved certification to ISO 13485. This certification is another way they are making constant ... and services that they need. , The ISO 13485 Certification is a major accomplishment ...
(Date:1/18/2017)... ... January 18, 2017 , ... The Hear ... aid project with the donation of cochlear implants. In February 2017, the first ... thus a fair chance of leading an independent life. This engagement builds on ...
(Date:1/17/2017)... , ... January 17, 2017 , ... January is National Stalking Awareness Month ... to lurk in the corners and commit the crime of stalking, a very real danger ... addiction, an often overlooked factor in stalking and other crimes. , “Stalking: know it. Name ...
Breaking Medicine News(10 mins):
(Date:1/18/2017)... 2017 Safe Rx LLC and Good Day ... Loveland, Colorado , today announced the ... Good Day locations.     "Patients with prescriptions ... secure storage," said Milton Cohen , President & ... of a cup of coffee, you can protect your ...
(Date:1/18/2017)... 2017 Invetech, the leading developer of ... therapies , has announced a collaboration agreement with ... starvation" treatments for acute leukemia and other oncology ... Invetech will develop systems to enable the commercial-scale ... technology platform, which uses a novel technology to ...
(Date:1/18/2017)... NEW YORK , January 18, 2017 ... perception of people regarding the use of cannabis both for ... not only are more Americans open to the use of ... and financial sectors. According to Arcview Market Research, the North ... 2016, up 30% from the previous year. The research projects ...
Breaking Medicine Technology: