Navigation Links
Scientists Find Clue to Aging Reversal in Mice
Date:1/31/2013

THURSDAY, Jan. 31 (HealthDay News) -- A discovery about the aging process in mice might one day help efforts to develop treatments for age-related diseases in humans, researchers report.

The biologists say they turned back the "molecular clock" in old mice by placing a "longevity" gene into their blood stem cells.

The gene, called SIRT3, belongs to a class of proteins called sirtuins, which help aged blood stem cells handle stress. Placing SIRT3 into the blood stem cells of old mice increased the formation of new blood cells, the investigators found. This, according to the researchers, is evidence of a reversal in the age-related decline in the old stem cells' function.

"We already know that sirtuins regulate aging, but our study is really the first one demonstrating that sirtuins can reverse aging-associated degeneration, and I think that's very exciting," study principal investigator Danica Chen, an assistant professor of nutritional science and toxicology at the University of California, Berkeley, said in a university news release.

The finding "opens the door to potential treatments for age-related degenerative diseases," Chen said.

The study was published online Jan. 31 in the journal Cell Reports.

Research over the past 10 to 20 years has led to breakthroughs in the understanding of aging, Chen said. Whereas aging had been previously looked upon as a random and uncontrolled process, it is now believed to be highly regulated and possibly even open to manipulation, she noted.

"Studies have already shown that even a single gene mutation can lead to lifespan extension," Chen said. "The question is whether we can understand the process well enough so that we can actually develop a molecular fountain of youth. Can we actually reverse aging? This is something we're hoping to understand and accomplish."

Experts note, however, that results from animal research are not always able to be replicated in humans.

More information

The U.S. National Institute on Aging offers healthy aging tips.

-- Robert Preidt

SOURCE: University of California, Berkeley, news release, Jan. 31, 2013


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Leading researchers warn of brain drain as scientists struggle to find funding
2. UNC scientists unveil a superbugs secret to antibiotic resistance
3. Scientists learn more about how inhibitory brain cells get excited
4. New target to stop cancers spread discovered by Georgia State scientists
5. Scientists create 1-step gene test for mitochondrial diseases
6. Scientists Complete 1st Map of Emotional Intelligence in the Brain
7. Singapore scientists led by A*STARs GIS identify 4 mechanisms that contribute to gastric cancers
8. National Cancer Centre Singapore scientists discover p53 mutation hinders cancer treatment response
9. HIV-Like Virus Arose in Primates Millions of Years Ago, Scientists Say
10. Scientists Link More Genes to Common Brain Tumor
11. Temple scientists find cancer-causing virus in the brain, potential connection to epilepsy
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Scientists Find Clue to Aging Reversal in Mice
(Date:6/24/2016)... ... June 24, 2016 , ... ... Sessions in Dallas that it will receive two significant new grants to support ... as PHA marked its 25th anniversary by recognizing patients, medical professionals and scientists ...
(Date:6/24/2016)... San Diego, CA (PRWEB) , ... June 24, 2016 , ... ... up with the American Cancer Society and the Road To Recovery® program to drive ... care to seniors and other adults to ensure the highest quality of life and ...
(Date:6/24/2016)... Norcross, Georgia (PRWEB) , ... June 24, 2016 ... ... Year” awards today at the Clinical Decision Making in Emergency Medicine conference in ... who have authored journal articles published in Emergency Medicine Practice and ...
(Date:6/24/2016)... ... June 24, 2016 , ... Strategic Capital Partners, ... economy by obtaining investment capital for emerging technology companies. SCP has delivered ... already resulted in more than a million dollars of capital investment for five ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... ... for human induced pluripotent stem (iPS) cells and other difficult to transfect cells, ... Cloning Medium. The PluriQ™ G9™ Gene Editing System is a complete ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016   Pulmatrix, Inc ... company developing innovative inhaled drugs, announced today that it ... Russell Investments reconstituted its comprehensive set of U.S. ... "This is an important milestone for Pulmatrix," said ... increase shareholder awareness of our progress in developing drugs ...
(Date:6/24/2016)...  Arkis BioSciences, a leading innovator in the ... cerebrospinal fluid treatments, today announced it has secured ... led by Innova Memphis, followed by Angel Capital ... Arkis, new financing will accelerate the commercialization of ... of its in-licensed Endexo® technology. ...
(Date:6/23/2016)... 2016 Research and Markets has announced ... Forecast to 2022" report to their offering. ... the patients with kidney failure, it replaces the function of ... patient,s blood and thus the treatment helps to keep the ... balance. Increasing number of ESRD patients & ...
Breaking Medicine Technology: