Navigation Links
Scientists Find Clue to Aging Reversal in Mice

THURSDAY, Jan. 31 (HealthDay News) -- A discovery about the aging process in mice might one day help efforts to develop treatments for age-related diseases in humans, researchers report.

The biologists say they turned back the "molecular clock" in old mice by placing a "longevity" gene into their blood stem cells.

The gene, called SIRT3, belongs to a class of proteins called sirtuins, which help aged blood stem cells handle stress. Placing SIRT3 into the blood stem cells of old mice increased the formation of new blood cells, the investigators found. This, according to the researchers, is evidence of a reversal in the age-related decline in the old stem cells' function.

"We already know that sirtuins regulate aging, but our study is really the first one demonstrating that sirtuins can reverse aging-associated degeneration, and I think that's very exciting," study principal investigator Danica Chen, an assistant professor of nutritional science and toxicology at the University of California, Berkeley, said in a university news release.

The finding "opens the door to potential treatments for age-related degenerative diseases," Chen said.

The study was published online Jan. 31 in the journal Cell Reports.

Research over the past 10 to 20 years has led to breakthroughs in the understanding of aging, Chen said. Whereas aging had been previously looked upon as a random and uncontrolled process, it is now believed to be highly regulated and possibly even open to manipulation, she noted.

"Studies have already shown that even a single gene mutation can lead to lifespan extension," Chen said. "The question is whether we can understand the process well enough so that we can actually develop a molecular fountain of youth. Can we actually reverse aging? This is something we're hoping to understand and accomplish."

Experts note, however, that results from animal research are not always able to be replicated in humans.

More information

The U.S. National Institute on Aging offers healthy aging tips.

-- Robert Preidt

SOURCE: University of California, Berkeley, news release, Jan. 31, 2013

Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Leading researchers warn of brain drain as scientists struggle to find funding
2. UNC scientists unveil a superbugs secret to antibiotic resistance
3. Scientists learn more about how inhibitory brain cells get excited
4. New target to stop cancers spread discovered by Georgia State scientists
5. Scientists create 1-step gene test for mitochondrial diseases
6. Scientists Complete 1st Map of Emotional Intelligence in the Brain
7. Singapore scientists led by A*STARs GIS identify 4 mechanisms that contribute to gastric cancers
8. National Cancer Centre Singapore scientists discover p53 mutation hinders cancer treatment response
9. HIV-Like Virus Arose in Primates Millions of Years Ago, Scientists Say
10. Scientists Link More Genes to Common Brain Tumor
11. Temple scientists find cancer-causing virus in the brain, potential connection to epilepsy
Post Your Comments:
Related Image:
Scientists Find Clue to Aging Reversal in Mice
(Date:10/13/2015)... ... October 13, 2015 , ... Purdue University announced Tuesday (Oct. ... Initiative aimed at enhancing Purdue’s life sciences research and graduate education. The initiative ... , The investment will result in cohesive efforts across several colleges and is ...
(Date:10/13/2015)... ... 13, 2015 , ... "My friend's son suffers from eczema, and he had ... an inventor from Platteville, Colo. "I came up with this kit as a way ... to prevent a child from rubbing or scratching his or her face. This protects ...
(Date:10/13/2015)... (PRWEB) , ... October 13, 2015 , ... ProText Kinetic ... X . With ProText Kinetic Panel, users can create energetic text animations in any ... preset into the Final Cut Pro X timeline and stylize the text. With intuitive ...
(Date:10/13/2015)... ... October 13, 2015 , ... Relay (, a technology ... today a significant contract that will provide its award-winning private messaging solution to ... the growing success of its Relay program, IBX Wire™, which now has over ...
(Date:10/13/2015)... ... October 13, 2015 , ... Leading Internet marketing product review ... "Publish Academy" training course . Singal's new program, in which he reveals his ... around the Internet are weighing in with reviews. , "Considering the fairly high ...
Breaking Medicine News(10 mins):
(Date:10/13/2015)... 2015  Nanomedical Diagnostics, a biotech company developing ... diagnostics, announces the completion of a Series A ... Ventures. --> ... monitoring and diagnostic platforms that empower individuals to ... will enable the company to commercially release AGILE ...
(Date:10/13/2015)... Oct. 9, 2015 Research and Markets ( ... "Kombucha Market by Types (Bacteria, Yeast, Mold, Others), Flavors ... Flowers, Others), & by Region - Forecasts to 2020" ... --> --> The global ... few years. In terms of value, the market is ...
(Date:10/13/2015)... Oct. 13, 2015   Micell Technologies , Inc. ... and II trials of its MiStent Sirolimus Eluting Absorbable ... ) were presented at the 27th Annual Transcatheter Cardiovascular ... San Francisco , October 11-15. TCT is the ... MiStent SES was designed to optimize vessel healing in ...
Breaking Medicine Technology: