Navigation Links
Rooting out recurrent breast cancer
Date:2/8/2013

Due to chemotherapy resistance and a high rate of relapse, triple negative cancers are among the most difficult breast cancers to treat. In this issue of the Journal of Clinical Investigation, researchers led by Carlos Arteaga at Vanderbilt University identified a protein, TGF-β, that is highly expressed in triple negative breast cancer cells after chemotherapy. In a mouse model of breast cancer, TGF-β both diverted cells down a path to becoming cancerous and allowed for cancer to come back after treatment. Importantly, loss of TGF-β prevented tumor recurrence in mice. These studies identify a mechanism by which cancer cells elude standard chemotherapy and provide a rationale for testing the therapeutic potential of agents that block TGF-β.


'/>"/>

Contact: Jillian Hurst
press_releases@the-jci.org
Journal of Clinical Investigation
Source:Eurekalert

Page: 1

Related medicine news :

1. Study drug is first to help patients with recurrent low-grade ovarian cancer
2. Unnecessary antimicrobial use increases risk of recurrent infectious diarrhea
3. Research shows that a prolonged fertility window can cause recurrent miscarriage
4. Common data determinants of recurrent cancer are broken, mislead researchers
5. Immune system changes may drive aggressiveness of recurrent tumors
6. Benefit of PET or PET/CT in recurrent bowel cancer is not proven
7. Mayo Clinic gets FDA approval for new imaging agent for recurrent prostate cancer
8. Daily Aspirin May Help Those at Risk for Recurrent Blood Clots
9. Study suggests new way to prevent recurrent ear infections
10. Current and former smokers at risk for recurrent hepatitis post-liver transplantation
11. Breast-Feeding Still Less Common for Black Babies: CDC
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/19/2017)... , ... January 19, 2017 , ... Next week after ... be repealed by Congressional political games that circumvent health needs of over 30 million. ... capture the human anxieties and needs government public servants were suppose to prioritize. Interviews ...
(Date:1/19/2017)... , ... January 19, 2017 , ... With the cold weather here, many people will ... blowers are efficient when clearing large amounts of snow, but they can be dangerous when ... U.S. Consumer Product Safety Commission for the proper use of snow blowers:, ...
(Date:1/19/2017)... ... 19, 2017 , ... LabRoots , the leading provider ... world, announces the launch of its newly redesigned website. The sleek new design ... and trending news, vital information on upcoming virtual events and webinars, all while ...
(Date:1/19/2017)... ... January 19, 2017 , ... Remote Medical Technologies ... impressive transportable capabilities with their iMedHD2™ Portable Teleultrasound System. Compatible ... technology that delivers HD, dynamic, streaming ultrasound images and video to one or ...
(Date:1/19/2017)... ... January 19, 2017 , ... WholeHealth is announcing their ... Alexander Paziotopoulos, Andrew Petersen and Trish Henrie-Barrus will be present Saturday and Sunday ... recovery program. , “We know it’s easy to get carried away when ...
Breaking Medicine News(10 mins):
(Date:1/19/2017)... , Jan. 19, 2017 Accuray Incorporated (Nasdaq: ... and TomoTherapy® Systems continue to set the bar for ... highest composite overall user satisfaction rating among radiation treatment ... 2016 MD Buyline Market Intelligence Briefing™. The most recent ... composite ratings among industry peers for 11 of the ...
(Date:1/19/2017)... RATON, Fla. , Jan. 19, 2017 /PRNewswire/ ... a medical device company specializing in the treatment ... such as keloids, with superficial radiation therapy, today ... and full year 2016 financial results on Thursday, February ... The Company will hold a conference call with ...
(Date:1/19/2017)... PALO ALTO, Calif. , Jan. 19, 2017 /PRNewswire/ ... scientific research, is excited to announce that the ... Project: Cancer Biology  (RP:CB) have been published in ... science, this project represents the first practical evaluation ... that result in reproducible studies. Unlike other assessments ...
Breaking Medicine Technology: